跳到主要內容

臺灣博碩士論文加值系統

(216.73.216.230) 您好!臺灣時間:2026/10/26 11:52
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果 :::

詳目顯示

: 
twitterline
研究生:朱奐勤
研究生(外文):Huan-Chin Chu
論文名稱:飼糧中不同濃度或鏈長之中鏈三酸甘油酯對肉雞體脂蓄積、脂肪酸組成、血液性狀及葡萄糖耐受性之影響
論文名稱(外文):Effects of Different Levels or Chain Lengths of Medium-Chain Triglycerides in Diet on Fat Deposition, Fatty Acid Composition, Blood Parameters and Glucose Tolerance of Broilers
指導教授:姜樹興姜樹興引用關係
指導教授(外文):Shu-Hsing Chiang
口試委員:姜樹興、余碧、李恒夫、陳珠亮
口試委員(外文):Shu-Hsing Chiang、Bi Yu、Herng-Fu Lee、Chu-Liang Chen
口試日期:2013-06-21
學位類別:碩士
校院名稱:東海大學
系所名稱:畜產與生物科技學系
學門:農業科學學門
學類:畜牧學類
論文種類:學術論文
論文出版年:2013
畢業學年度:101
語文別:中文
論文頁數:102
中文關鍵詞:體脂蓄積、脂肪酸組成、葡萄糖耐受性、中鏈三酸甘油酯
外文關鍵詞:Fat deposition、Fatty acid composition、Glucose tolerance、Medium-chain triglyceride
相關次數:
  • 被引用被引用:3
  • 點閱點閱:936
  • 評分評分:
  • 下載下載:14
  • 收藏至我的研究室書目清單書目收藏:0
本試驗旨在探討飼糧中不同濃度或鏈長之中鏈三酸甘油酯(medium chain triglycerides;MCT)對肉雞體脂蓄積、脂肪酸組成、血液性狀及葡萄糖耐受性之影響。試驗一,600隻初生肉雞,逢機分配至四處理組,每處理六重複,每重複25隻,分別飼予含MCT(含C6:0,C8:0及C10:0)(1)0;(2)1.6;(3)4.0或(4)6.4%之玉米-大豆粕飼糧。試驗二,300隻初生肉雞,逢機分配至三處理組,每處理四重複,每重複25隻,分別飼予含4%大豆油、椰子油(含C12:0)或C6油(含C6:0)之玉米-大豆粕飼糧,試驗為期36日。測定肉雞之生長性能,腹脂蓄積,血漿中葡萄糖及膽固醇濃度,腹脂、胸肉及腿肉(帶皮)中總脂肪含量與脂肪酸組成及葡萄糖耐受性。試驗一結果顯示,飼糧中含6.4% MCT時,降低0-36日齡間增重及飼料採食量,腹脂蓄積及腿肉(帶皮)脂肪含量(P<0.05)。飼料利用效率及死亡率則各組間並無顯著差異。C6:0無法蓄積於組織中,C8:0及C10:0可蓄積於組織中,而以C10:0蓄積率較C8:0為佳,且以腿肉(帶皮)中蓄積率最高,胸肉最低。飼糧中含6.4% MCT時,肉雞血漿中膽固醇及HDL-膽固醇濃度顯著高於對照組(P<0.05)。葡萄糖濃度則未受飼糧中MCT濃度之影響。飼糧中不同濃度MCT皆改善肉雞葡萄糖耐受性(P<0.05)。試驗二結果顯示,飼糧中椰子油或C6油皆不影響肉雞0-36日齡間生長性能及體脂蓄積。C6:0無法蓄積於組織中,C12:0則可蓄積於組織中。飼糧中椰子油或C6油皆不影響肉雞血漿中膽固醇、葡萄糖濃度及葡萄糖耐受性。綜合以上, 飼糧中含C8:0及C10:0,可降低肉雞體脂肪蓄積,增加血漿中膽固醇及HDL-膽固醇濃度,並改善葡萄糖耐受性,C6:0及C12:0則否。C8:0,C10:0及C12:0可蓄積於體組織中,而C6:0則否。

Two trials were conducted to examine the effects of different levels or chain lengths of medium-chain triglycerides in diet on fat deposition, fatty acid composition, blood parameters and glucose tolerance of broilers. Trial 1, 600 newly hatched Arbor Acres chicks were allotted to four treatments, six replicates per treatment and 25 chicks per replicate. Chicks were fed diets containing (1) 0; (2) 1.6; (3) 4.0 or (4) 6.4% MCT (containing C6:0, C8:0 and C10:0) for 36 days. Trial 2, 300 newly hatched Arbor Acres chicks were allotted to three treatments, four replicates per treatment and 25 chicks per replicate. Chicks were fed diets containing 4% of (1) soybean oil; (2) coconut oil (containing C12:0) or (3) C6 oil (containin C6:0) for 36 days. Growth performances, abdominal fat deposition, plasma glucose and cholesterol levels, fat content and fatty acid composition of abdominal fat, breast and thigh meat (with skin), and glucose tolerance were measured.Results of trial 1 showed that diet containing 6.4% MCT decreased day 0-36 weight gain and feed intake, abdominal fat deposition and fat content of thigh (with skin) (P<0.05). Feed efficiency and mortality were not affected by the dietary MCT. C8:0 and C10:0 but not C6:0 could be deposited in the tissues. C10:0 had a better deposition efficiency than C8:0 had. Thigh (with skin) had a better deposition efficiency than breast had. Diet containing 6.4% MCT increased plasma total and HDL cholesterol content (P<0.05). Plasma glucose content was not affected but the glucose tolerance was improved (P<0.05) by the dietary MCT.Results of trial 2 showed that diet containing coconut oil or C6 oil did not affect day 0-36 growth performances and abdominal fat deposition. C12:0 but not C6:0 could be deposition in the tissues. Diet containing coconut oil or C6 oil did not affect plasma glucose, cholesterol levels, and glucose tolerance.In conclusion, diet containing C8:0 and C10:0 but not C6:0 or C12:0 could decrease the body fat deposition, increase plasma cholesterol and HDL-cholesterol, and improve the glucose tolerance in broilers. C8:0, C10:0 and C12:0 but not C6:0 could be deposited in the tissues of broilers.
目次--------------------------------------------------I
表次索引----------------------------------------------IV
圖次索引----------------------------------------------VI
文獻檢討-----------------------------------------------1
一、脂質之定義------------------------------------------1
二、脂質之分類------------------------------------------1
三、中鏈三酸甘油酯---------------------------------------8
摘要--------------------------------------------------37
前言--------------------------------------------------39
材料與方法---------------------------------------------42
結果--------------------------------------------------53
討論--------------------------------------------------74
結論--------------------------------------------------82
參考文獻-----------------------------------------------83
英文摘要-----------------------------------------------97
附錄--------------------------------------------------99

李德南、呂効儒、陳保基及楊天樹。2012。比較不同SAS程序分析動物試驗重複測量資料之差異。中畜會誌 41:177-186。

林玟君。2009。辛酸抑制雞前脂肪細胞之分裂。東海學報 50:9-15。

姜樹興、黃國雄及李恆夫。1990。中鏈三酸甘油酯對肉雞能量代謝、生長性能及體脂含量之影響。中畜會誌 19:11-18。

姜樹興編著。2009。動物營養學原理。華香園出版社。台北市。

黃玫僑。2011。飼糧中添加不同含量或來源中鏈三酸甘油酯對肉雞生長性能、腸道菌相及脂肪蓄積之影響。碩士論文。東海大學畜產研究所。

賴韋綱。2010。飼糧中添加中鏈三酸甘油酯對仔豬生長性能、腸道菌相或脛骨強度之影響。碩士論文。東海大學畜產研究所。

Agnew, J. E. and C. D. Holdsworth. 1971. The effect of fat on calcium absorption from a mixed meal in normal subjects, patients with malabsorptive disease, and patients with a partial gastrectomy. Gut 12:973-977.

Akoh, C. C. 2006. Handbook of Functional Lipids. CRC Press, Taylor & Francis Group LLC. Boca Raton, FL, USA.

Allee, G. L., D. R. Romsos, G. A. Leveille and D. H. Baker. 1972. Metabolic consequences of dietary medium-chain triglycerides in the pig. Proc. Biol. Med. 139:422-431.

Aoyama, T., N. Nosaka and M. Kasai. 2007. Research on the nutritional characteristics of medium-chain fatty acids. J. Med. Invest. 54:385-388.

Asakura, L., A. M. P. Lottenberg, M. Q. T. S. Neves, V. S. Nunes, J. C. Rocha, M. Passarelli, E. R. Nakandakare and E. C. R. Quintão. 2000. Dietary medium-chain triacylglycerol prevents the postprandial rise of plasma triacylglycerols but induces hypercholesterolemia in primary hypertriglyceridemic subjects. Am. J. Clin. Nutr. 71:701-705.

Baba, N., E. F. Bracco and S. A. Hashim. 1982. Enhanced thermogenesis and diminished deposition of fat in response to overfeeding with diets containing medium chain triglyceride. Amer. J. Clin. Nutr. 35:678-682.

Baba, N., E. F. Bracco and S. A. Hashim. 1987. Role of brown adipose tissue in thermogenesis induced by overfeeding a diet containing medium chain triglyceride. Lipids 22:442-444.

Bach, A. 1978. Oxaloacetate deficiency in MCT-induced ketogenesis. Arch. Int. Physiol. Biochem. 86:1133-1142.

Bach, A. C. and V. K. Babayan. 1982. Medium-chain triglycerides: An update. Am. J. Clin. Nutr. 36:950-962.

Barbera, R., M. Peracchi, F. Brighenti, B. Cesana, P. A. Bianchi and G. Basilisco. 2000. Sensations induced by medium and long chain triglycerides: role of gastric tone and hormones. Gut 46:32-36.

Bergman, R. N., S. P. Kim, I. R. Hsu, K. J. Catalano, J. D. Chiu, M. Kabir, J. M. Richey, and M. Ader. 2007a. Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. Am. J. Med. 120:S3-S8.

Bergman, B. C., Marc-Andre Cornier, T. J. Horton and D. H. Bessesen. 2007b. Effects of fasting on insulin action and glucose kinetics in lean and obese men and women. Am. J. Physiol. Endocrinol. Metab. 293:E1103-E1111.

Beynen, A. C., H. J. Kappert, A. G. Lemmens and A. M. van Dongen. 2002. Plasma lipid concentrations, macronutrient digestibility and mineral absorption in dogs fed a dry food containing medium-chain triglycerides. J. Anim. Physiol. Anim. Nutr. 86:306-312.

Bremer, J. 1980. Carnitine and its role in fatty acid metabolism. Trends Biochem. Sci. 2:207-209.

Chiang, S. H., J. E. Pettigrew, S. D. Clarke and S. G. Cornelius. 1990. Limits of medium-chain and long-chain triacylglycerol utilization by neonatal piglets. J. Anim. Sci. 68:1632-1638.

Costarelli, V. and T. A. B. Sanders. 2001. Acute effects of dietary fat composition on postprandial plasma bile acid and cholecystokinin concentrations in healthy premenopausal women. Br. J. Nutr. 86:471-477.

Dierick, N. A., J. A. Decuypere, K. Molly, E. Van Beek and E. Vanderbeke. 2002. The combined use of triacylglycerols containing medium-chain fatty acids (MCFAs) and exogenous lipolytic enzymes as an alternative for nutritional antibiotics in piglet nutrition: II. In vivo release of MCFAs in gastric cannulated and slaughtered piglets by endogenous and exogenous lipases; effects on the luminal gut fiora and growth performance. Livest. Prod. Sci. 76:1-16.

Folch, J., M. Lees and G. H. Sloane Stanley. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226:497-509.

Friedman, M. I., R. B. Harris, H. Ji, I. Ramirez and M. G. Tordoff. 1999. Fatty acid oxidation affects food intake by altering hepatic energy status. Am. J. Physiol. Regul. Integr. Comp. Physiol. 276:R1046-R1053.

Furuse, M., R. T. Mabayo, K. Kita and J. Okumura. 1992a. Effect of dietary medium chain triglyceride on protein and energy utilization in growing chicks. Br. Poult. Sci. 33:49-57.

Furuse, M., Y. H. Choi, R. T. Mabayo and J. Okumura. 1992b. Feeding behavior in rats fed diets containing medium chain triglyceride. Phys. Beh. 52:815-817.

Furuse, M., R. T. Mabayo, Y. H. Choi, D. M. Denbow and J. Okumura. 1993. Feeding behaviour in chickens given diets containing medium chain triglyceride. Br. Poult. Sci. 34:211-217.

Gallo-Torres, H. E., J. Ludorf and M. Brin. 1978. The effect of medium chain triglycerides on the bioavailability of vitamin E. Int. J. Vitam. Nutr. Res. 48:240-241.

Galluser, M., B. Czernichow, H. Dreyfus, F. Gosse, B. Guerold, J. Kachelhoffer, M. Doffoel and F. Raul. 1993. Comparison of different lipid substrates on intestinal adaptation in the rat. Gut 34:1069-1074.

Garcia-Lopez, S. and G. D. Miller. 1991. Bioavailability of calcium from four different sources. Nutr. Res. 11:1187-1196.

Guo, W., T. Lei, T. Wang, B. E. Corkey and J. Han. 2003. Octanoate inhibits triglyceride synthesis in 3T3-L1 and human adipocytes. J. Nutr. 133:2512-2518.

Guyton, A. C. 1982. Dietary balances, regulation of feeding, obesity, and vitamins. In: A. C. Guyton (Ed.) Human Physiology and Mechanisms of Disease, pp. 558-567. Saunders, Philadelphia, USA.

Hallebeek, J. M. and A. C. Beynen. 2003. Production and clearance of plasma triacylglycerols in ponies fed diets containing either medium-chain triacylglycerols or soya bean oil. J. Anim. Physiol. Anim. Nutr. 87:188-195.

Han, J. R., J. A. Hamilton, J. L. Kirkland, B. E. Corkey and W. Guo. 2003. Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats. Obes. Res. 11:734-744.

Han, J. R., B. Deng, J. Sun, C. G. Chen, B. E. Corkey, J. L. Kirkland, J. Ma and W. Guo. 2007. Effects of dietary medium-chain triglyceride on weight loss and insulin sensitivity in a group of moderately overweight free-living type 2 diabetic Chinese subjects. Metabolism 56:985-991.

Hashim, S. A. and P. Tantibhedyangkul. 1987. Medium chain triglyceride in early life: effects on growth of adipose tissue. Lipids 22:429-434.

Henderson, S. T. 2002. Use of medium chain triglycerides for the treatment and prevention of Alzheimer’s disease and other diseases resulting from reduced neuronal metabolism. US Patent Application US 2002/0006959 A1.

Hill, J. O., J. C. Peters, D. Yang, T. Sharp, M. Kaler, N. N. Abumrad and H. L. Greene. 1989. Thermogenesis in humans during overfeeding with medium-chain triglycerides. Metabolism 38:641-648.

Hoeks, J., M. Mensink, M. K. C. Hesselink, K. Ekroos and P. Schrauwen. 2012. Long- and medium-chain fatty acids induce insulin resistance to a similar extent in humans despite marked differences in muscle fat accumulation. J. Clin. Endocrinol. Metab. 97:208-216.

Holtzapple, P., W. Berman and S. Segal. 1972. Enhancement of non-electrolyte transport in jejunal mucosa by fatty acids. Gastroenterology 62:849 (Abstr.).

Jensen, G. L., E. A. Mascioli, D. L. Seidner, N. W. Istfan, A. M. Domnitch, K. Selleck, V. K. Babayan, G. L. Blackburn and B. R. Bistrian. 1990. Parenteral infusion of long- and medium-chain triglycerides and reticuloendothelial system function in man. J. Parenter. Enteral. Nutr. 14:467-471.

Johnson, R. C. and R. Cotter. 1986. Metabolism of medium chain triglyceride emulsion. Nutr. Int. 2:150-158.

Kasai, M., N. Nosaka, H. Maki, Y. Suzuki, H. Takeuchi, T. Aoyama, A. Ohra, Y. Harada, M. Okazaki and K. Kondo. 2002. Comparison of diet-induced thermogenesis of foods containing medium-versus long-chain triacylglycerols. J. Nutr. Sci. Vitaminol. 48:536-540.

Kasai, M., H. Maki, N. Nosaka, T. Aoyama, K. Ooyama, H. Uto, M. Okasaki, O. Igarashi and K. Kondo. 2003a. Effect of medium-chain triglycerides on postprandial triglyceride concentrations in healthy men. Biosci. Biotechnol. Biochem. 67:46-53.

Kasai, M., H. Maki, Y. Suzuki, N. Nosaka, T. Aoyama, H. Inuzaka, M. Okazaki, O. Igarashi and K. Kondo. 2003b. Effect of medium-chain triglycerides on postprandial concentrations of remnant-like particles (RLP) in healthy men. J. Oleo Sci. 52:197-204.

Kasai, M., N. Nosaka, H. Maki, S. Negishi, T. Aoyama, M. Nakamura, Y. Suzuki, H. Tsuji, H. Uto, M. Okazaki and K. Kondo. 2003c. Effect of dietary medium- and long-chain triacylglycerols (MLCT) on accumulation of body fat in healthy humans. Asia. Pac. J. Clin. Nutr. 12:151-160.

Kim, S. P., K. J. Catalano, I. R. Hsu, J. D. Chiu, J. M. Richey and R. N. Bergman. 2007. Nocturnal free fatty acids are uniquely elevated in the longitudinal development of diet-induced insulin resistance and hyperinsulinemia. Am. J. Physiol. Endocrinol. Metab. 292:E1590-E1598.

Kimoto, Y., Y. Tanji, T. Taquchi, T. Suqimoto, T. Watanabe, F. Tsukamoto, S. Kim, K. Yoneda, Y. Takamura, M. Izukura, E. Shiba and S. Takai. 1998. Antitumor effect of medium-chain triglyceride and its influence on the self-defense system of the body. Cancer Detect. Prev. 22:219-224.

Kouba, M. and J. Mourot. 1998. Effect of a high linoleic acid diet on delta 9-desaturase activity, lipogenesis and lipid composition of pig subcutaneous adipose tissue. Reprod. Nutr. Dev. 38:31-37.

Krogdahl, A. 1985. Digestion and absorption of lipids in poultry. J. Nutr. 115:675-685.

Lavau, M. M. and S. A. Hashim. 1978. Effect of medium chain triglyceride on lipogenesis and body fat in the rat. J. Nutr. 108:613-620.

Likhodii, S. S., K. Musa, A. Mendoca, C. Dell, W. M. Burnham and S. C. Cunnane. 2000. Dietary fat, ketosis, and seizure resistance in rats on the ketogenic diet. Epilepsia 41:1400-1410.

Lin, C. L., S. H. Chiang and H. F. Lee. 1995. Causes of reduced survival of neonatal pigs by medium-chain triglycerides: blood metabolite and behavioral activity approaches. J. Anim. Sci. 73:2019-2025.

Mabayo, R. T., F. Mitsuhiro, Y. Sungik and O. Junichi. 1992. Medium-chain tricylglycerols enhance release of cholecystokinin in chicks. J. Nutr. 122:1702-1705.

Mabayo, R. T., F. Mitsuhiro, K. Kita and O. Junichi. 1993. Improvement of dietary protein utilization in chicks by medium chain triglyceride. Br. Poult. Sci. 34:121-130.

Mabayo, R. T., J. Okumura, A. Hirao, S. Sugita, K. Sugahara and M. Furuse. 1996. The role of olfaction in oil preference in the chicken. Physiol. Behav. 59:1185-1188.

Marten, B., M. Pfeuffer and J. Schrezenmeir. 2006. Medium-chain triglycerides: Review. Int. Dairy J. 16:1374-1382.

Matsuo, T. and H. Takeuchi. 2004. Effects of structured medium- and long-chain triacylglycerols in diets with various levels of fat on body fat accumulation in rats. Br. J. Nutr. 91:219-225.

Matulka, R. A., D. V. M. Larry Thompson and G. A. Burdock. 2009. Lack of toxicity by medium chain triglycerides (MCT) in canines during a 90-day feeding study. Food Chem. Toxicol. 47:35-39.

McCandeless, D. W. 1985. Octanoic acid-induced coma and reticular formation energy metabolism. Brain Res. 335:131-137.

McGarry, J. D. and D. W. Foster. 1980. Regulation of hepatic fatty acid oxidation and ketone body production. Ann. Rev. Biochem. 49:395-420.

Miles, J. M., M. Cattalini, F. W. Sharbrough, L. E. Wold, R. E. Wharen, J. E. Gerich and M. W. Haymond. 1991. Metabolic and neurologic effects of an intravenous medium-chain triglyceride emulsion. J. Parenter. Enteral. Nutr. 15:37-41.

Nagao, K. and T. Yanagita. 2010. Medium-chain fatty acids: Functional lipids for the prevention and treatment of the metabolic syndrome. Pharmacol. Res. 61:208-212.

Newport, M. J., J. E. Storry and B. Tuckley. 1979. Artificial rearing of pigs. 7. Medium chain triglycerides as a dietary source of energy and their effect on live-weight gain, feed:gain ratio, carcass composition and blood lipids. Br. J. Nutr. 41:85-93.

Nishi, Y., H. Hiejima, H. Hosoda, H. Kaiya, K. Mori, Y. Fukue, T. Yanase, H. Nawata, K. Kangawa and M. Kojima. 2005. Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin. Endocrinology 146:2255-2264.

Nosaka, N., M. Kasai, M. Nakamura, I. Takahashi, M. Itakura, H. Takeuchi, T. Aoyama, H. Tsuji, M. Okazaki and K. Kondo. 2002. Effects of dietary medium-chain triacylglycerols on serum lipoproteins and biochemical parameters in healthy men. Biosci. Biotechnol. Biochem. 66:1713-1718.

Nosaka, N., H. Maki, Y. Suzuki, H. Haruna, A. Ohara, M. Kasai, H. Tsuji, T. Aoyama, M. Okazaki, O. Igarashi and K. Kondo. 2003. Effects of margarine containing medium-chain triacylglycerols on body fat reduction in humans. J. Atheroscler. Thromb. 10:290-298.

NRC. 1994. Nutrient Requirements of Poultry. 9th rev. ed. National Academy Press, Washington, DC.

Odle, J., N. J. Benevenga and T. D. Crenshaw. 1992. Evaluation of [1-14c]-medium-chain fatty acid oxidation by neonatal piglets using continuous-infusion radiotracer kinetic methodology. J. Nutr. 122:2183-2189.

Ogawa, A., N. Nosaka, M. Kasai, T. Aoyama, M. Okazaki, O. Igarashi and K. Kondo. 2007. Dietary medium- and long-chain triacylglycerols accelerate diet-induced thermogenesis in humans. J. Oleo Sci. 56:283-287.

Ooyama, K., K. Keiichi, A. Toshiaki and T. Hiroyuki. 2009. Decrease of food intake in rats after ingestion of medium-chain triacylglycerol. J. Nutr. Sci. Vit. 55:423-427.

Papamandjaris, A. A., D. E. MacDougall and P. J. Jones. 1998. Medium chain fatty acid metabolism and energy expenditure: obesity treatment implications. Life Sci. 62:1203–1215.

Papamandjaris, A. A., M. D. White, M. Raeini-Sarjaz and P. J. Jones. 2000. Endogenous fat oxidation during medium chain versus long chain triglyceride feeding in healthy women. Int. J. Obes. Relat. Metab. Disord. 24:1158-1166.

Papavassilis, C. 2000. Use of medium-chain triacylglycerols in parenteral nutrition of children. Nutrition 16:460-461.

Ramirez, I. 1993. Role of olfaction in starch and oil preference. Am. J. Physiol. 265: 1404-1409.

Robinson, A. M. and D. H. Williamson. 1980. Physiological roles of ketone bodies as substrates and signals in mammalian tissues. Physiol. Rev. 60:143-187.

Roels, O. A. and S. A. Hashim. 1962. Influence of fatty acids on serum cholesterol. Fed. Proc. 21:71-76.

Ruppin, D. C. and W. R. J. Middleton. 1980. Clinical use of medium chain triglycerides. Drugs 20:216-224.

Ryo, M., T. Nakamura, S. Kihara, M. Kumada, S. Shibazaki, M. Takahashi, M. Nagai, Y. Matsuzawa and T. Funahashi. 2004. Adiponectin as a biomarker of the metabolic syndrome. Circ. J. 68:975-981.

Samson, F. E., N. Dahl and D. R. Dehl. 1956. A study on the narcotic action of short-chain fatty acids. J. Clin. Invest. 35:1291-1298.

SAS, 2000. SAS User’ s Guide: Statistical, SAS Inst., Inc., Cary, NC, USA.

Scalfi, L., A. Coltorti and F. Contaldo. 1991. Postprandial thermogenesis in lean and obese subjects after meals supplemented with medium-chain and long-chain triglycerides. Am. J. Clin. Nutr. 53:1130-1133.

Seaton, T. B., S. L. Welle, M. K. Warenko and R. G. Campbell. 1986. Thermic effect of medium-chain and long-chain triglycerides in man. Am. J. Clin. Nutr. 44:630-634.

Shinohara, H., J. Wu, M. Kasai and T. Aoyama. 2006. Randomly interesterified triacylglycerol containing medium- and long-chain fatty acids stimulates fatty acid metabolism in white adipose tissue of rats. Biosci. Biotechnol. Biochem. 70:2919-2926.

Shinohara, H., J. Wu and T. Aoyama. 2010. Effect of randomly interesterified triacylglycerol containing medium- and long-chain fatty acids on hepatic fatty acid oxidation after a single administration to rats. Biosci. Biotechnol. Biochem. 74:2336-2338.

Shulman, G. I. 2000. Cellular mechanisms of insulin resistance. J. Clin. Invest. 106:171-176.

Simoens, C. M., R. J. Deckelbaum, J. J. Massaut and Y. A. Carpentier. 2008. Inclusion of 10% fish oil in mixed medium-chain triacylglycerol–long-chain triacylglycerol emulsions increases plasma triacylglycerol clearance and induces rapid eicosapentaenoic acid (20:5n-3) incorporation into blood cell phospholipids. Am. J. Clin. Nutr. 88:282-288.

Sinsigalli, N. A., J. P. McMurtry, J. A. Cherry and P. B. Siegel. 1987. Glucose tolerance, plasma insulin and immunoreactive glucagon in chickens selected for high and low body weight. J. Nutr. 117:941-947.

Skrivanova, V. and M. Marounek. 2002. Effects of caprylic acid on performance and mortality of growing rabbits. Acta Vet. Brno 71:435-439.

Skrivanova, V. and M. Marounek. 2006. A note on the effect of triacylglycerols of caprylic and capric acid on performance, mortality, and digestibility of nutrients in young rabbits. Anim. Feed Sci. Technol. 127:161-168.

Skrivanova, E. Z. Molatova, V. Skrivanova and M. Marounek, 2009. Inhibitory activity of rabbit milk and medium-chain fatty acids against enteropathogenic Escherichia coli O128. Vet. Micro. 135:358-362.

Smink, W., W. J. Gerrits, R. Hovenier, M. J. Geelen, M. W. Verstegen and A. C. Beynen. 2010. Effect of dietary fat sources on fatty acid deposition and lipid metabolism in broiler chickens. Poult. Sci. 89:2432-2440.

St-Onge, M. P. and P. J. Jones. 2002. Physiological effects of medium-chain triglycerides: potential agents in the prevention of obesity. J. Nutr. 132:329–332.

St-Onge, M. P. and P. J. Jones. 2003. Greater rise in fat oxidation with medium-chain triglyceride consumption relative to long-chain triglyceride is associated with lower initial body weight and greater loss of subcutaneous adipose tissue. Int. J. Obes. Relat. Metab. Disord. 27:1565-1571.

St-Onge, M. P. and A. Bosarge. 2008. Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil. Am. J. Clin. Nutr. 87:621-626.

St-Onge, M. P., C. Bourque, P. J. Jones, R. Ross and W. E. Parsons. 2003a. Medium-versus longchain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. Int. J. Obes. Relat. Metab. Disord. 27:95-102.

St-Onge, M. P., R. Ross, W. D. Parsons and P. J. Jones. 2003b. Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men. Obes. Res. 11:395-402.

Studzinski, C. M., W. A. MacKay, T. L. Beckett, S. T. Henderson, M. P. Murphy, P. G. Sullivan and W. M. Burnham. 2008. Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-β precursor protein (APP) levels in the aged dog. Brain Res. 1226:209-217.

Sukhija, P. S., and D. L. Palmquist. 1988. Rapid method for determination of total fatty acid content and composition of feedstuffs and feces. J. Agric. Food Chem.36:1202-1206.

Sulkers, E. J., H. N. Lafeber, H. J. Degenhart, J. Lindemans and P. J. J. Sauer. 1992. Comparison of two preterai formulas with or without addition of medium-chain triglycerides (MCTs). II: effects on mineral balance. J. Pediatr. Gastroenterol. Nutr. 15:42-47.

Swift, L. L., J. O. Hill, J. C. Peters and H. L. Greene. 1992. Plasma lipids and lipoproteins during 6 d of maintenance feeding with long-chain, medium-chain, and mixed-chain triglycerides. Am. J. Clin. Nutr. 56:881-886.

Taha, A. Y., M. A. Ryan and S. C. Cunnane. 2005. Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats. Metabolism 54:1127-1132.

Taha, A. Y., S. T. Henderson and W. M. Burnham. 2009. Dietary enrichment with medium chain triglycerides (AC-1203) elevates polyunsaturated fatty acids in the parietal cortex of aged dogs: implications for treating age-related cognitive decline. Neuro. Chem. Res. 34:1619-1625.

Takahashi, Y. I. and B. A. Underwood.1974. Effect of long and medium chain length lipids upon aqueous solubility of α-tocopherol. Lipids 9:855-859.

Takase, S. and T. Coda. 1990. Effects of medium-chain triglycerides on brush border membrane-bound enzyme activity in rat small intestine. J. Nutr. 120:969-976.

Takeuchi, H., F. Kubota, M. Itakura and N. Taguchi. 2001. Effect of triacylglycerols containing medium- and long-chain fatty acids on body fat accumulation in rats. J. Nutr. Sci. Vitaminol. 47:267-269.

Takeuchi, H., O. Noguchi, S. Sekine, A. Kobayashi and T. Aoyama. 2006. Lower weight gain and higher expression and blood levels of adiponectin in rats fed medium-chain TAG compared with long-chain TAG. Lipids 41:207-212.

Tantibhedhyangkul, P. and S. A. Hashim. 1975. Medium-chain triglyceride feeding in premature infants: effects of fat and nitrogen absorption. Pediatrics 55:359-369.

Tantibhedhyangkul, P. and S. A. Hashim. 1978. Medium-chain triglyceride feeding in premature infants: effects on calcium and magnesium absorption. Pediatrics 61:537-545.

Terada, S., S. Yamamoto, S. Sekine and T. Aoyama. 2012. Dietary intake of medium- and long-chain triacylglycerols ameliorates insulin resistance in rats fed a high-fat diet. Nutrition 28:92-97.

Thavendiranathan, P., A. Mendonca, C. Dell, S. S. Likhodii, K. Musa, C. Iracleous, S. C. Cunnane and W. M. Burnham. 2000. The MCT ketogenic diet: effects on animal seizure models. Exp. Neurol. 161:696-703.

Tholstrup, T., C. Ehnholm, M. Jauhiainen, M. Petersen, C. E. Høy, P. Lund and B. Sandström. 2004. Effects of medium-chain fatty acids and oleic acid on blood lipids, lipoproteins, glucose, insulin, and lipid transfer protein activities. Am. J. Clin. Nutr. 79:564-569.

Travis, D., A. Minenna and H. Frier. 1979. Effects of medium-chain triglyceride on energy metabolism and body composition in the rat. Fed. Proc. 38:561 (Abstr.).

Tsuji, H., M. Kasai, H. Takeuchi, M. Nakamura, M. Okazaki and K. Kondo. 2001. Dietary medium-chain triacylglycerols suppress accumulation of body fat in a double-blind, controlled trial in healthy men and women. J. Nutr. 131:2853-2859.

Tucci, S., U. Flogel, M. Sturm, E. Borsch and U. Spiekerkoetter. 2011. Disrupted fat distribution and composition due to medium-chain triglycerides in mice with a β-oxidation defect. Am. J. Clin. Nutr. 94:439-449.

Turner, N., K. Hariharan, J. TidAng, G. Frangioudakis, S. M. Beale, L. E. Wright, X. Y. Zeng, S. J. Leslie, J.Y. Li, E. W. Kraegen, G. J. Cooney and J. M. Ye. 2009. Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids. Diabetes 58:2547-2554.

Walker, C. O., D. W. McCandless and I. D. McGarry. 1970. Cerebral energy metabolism in short-chain fatty acid induced coma. J. Lab. Clin. Med. 76:569-583.

Wang, H., A. W. Dudley, J. Dupont, P. J. Reeds, D. L. Hachey and M. A. Dudley. 1996. The duration of medium-chain triglyceride feeding determines brush border membrane lipid composition and hydrolase activity in newly weaned rats. J. Nutr. 126:1455-1462.

Wein, S., S. Wolffram, J. Schrezenmeir, D. Gasperikova, I. Klimes and E. Sebokova. 2009. Medium-chain fatty acids ameliorate insulin resistance caused by high-fat diets in rats. Diabetes Metab. Res. Rev. 25:185-194.

Wieland, T. M., X. Lin and J. Odle. 1993. Utilization of medium-chain triglycerides by neonatal pigs: effect of emulsification and dose delivered. J. Anim. Sci. 71:1863-1870.

Xue, C., Y. Liu, J. Wang, Z. Zheng, Y. Zhang, Y. Zhang, R. Zhang, X. Yu, H. Jin, N. Nosaka, C. Arai, M. Kasai, T. Aoyama and J. Wu. 2009. Chinese hypertriglycerideamic subjects of different ages responded differently to consuming oil with medium- and long-chain fatty acids. Biosci. Biotechnol. Biochem. 73:1711-1717.

Yeh, Y. Y. and P. Zee. 1976. Relation of ketosis to metabolic changes induced by acute medium-chain triglyceride feeding in rats. J. Nutr. 106:58-67.

Zhang, Y., Y. Liu, J. Wang, R. Zhang, H. Jing, X. Yu, Y. Zhang, Q. Xu, J. Zhang, Z. Zhang, N. Nosaka, C. Arai, M. Kasai, T. Aoyama, J. Wu and C. Xue. 2010. Medium- and long-chain triacylglycerols reduce body fat and blood triacylglycerols in hypertriacylglycerolemic, overweight but not obese, Chinese individuals. Lipids 45:501-510.

連結至畢業學校之論文網頁點我開啟連結
註: 此連結為研究生畢業學校所提供,不一定有電子全文可供下載,若連結有誤,請點選上方之〝勘誤回報〞功能,我們會盡快修正,謝謝!
QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top