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Effects of menstrual cycle on metabolic responsesto high-
intensity exercise were studied in exercising females. Eight
female subjects during follicular (6-9 days after menses) and
luteal (5-9 days after ovulation) phases of the menstrual cycle
were investigated. They received no contraceptives . They were
18.6±0.6 yr of age,163.1±1.3 cm of height,55.3±2.2 kg of
Weight,and 2.3 ±0.1 L/min of VO2peak. They were investigated
at 90% VO2peak to exhausting. Occurrence of ovulation was con-
firmed in all subjects by measurement of oral temperature and
progesterone concentration. The concentration of serum proges-
terone increased from 1.29±0.29 ng/ml in follicular phase to
4.86±1.35ng/ml in luteal phase. Exhausting time、 serum pro-
gesterone concentration and serum estradiol concentration at 5
min after exhausting were higher in luteal phase than in folli-
cular phase (p<0.01,p<0.05,and p<0.05). The blood glucose level
was lower in luteal phase than in follicular phase (p<0.05).
There was no significant difference in serum testosterone and
blood lactate concentrations between follicular and luteal pha-
ses. Negative correlation between serum estradiol and blood
glu- cose concentrations in luteal phase (r=-0.336,p=0.054) was
obser- ved. There was no significant correlation among blood
lactate、 serum estradiol and serum progesterone
concentrations. These results indicate that the increased
exhausting time du- ring luteal phase is associated with an
increase of the serum levels of both estradiol and
progesterone. These data suggest that exercise performance can
be stimulated by an additive sy- nergistic effect between
estradiol and progesterone.
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