|
1.Oender K, Trost A, Lanschuetzer C et al. Cytokeratin-related loss of cellular integrity is not a major driving force of human intrinsic skin aging. Mech Ageing Dev 2008: 129: 563–571.
2.Fisher G J, Kang S, Varani J et al. Mechanism of photoaging and chronological skin aging. Arch Dermatol 2002: 138: 1462–1470.
3.Callaghan T M, Wilhelm K P. A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part I: cellular and molecular perspectives of skin ageing. Int J Cosmetic Sci 2008: 30: 313–322.
4.Makrantonaki E, Zouboulis C C. Molecular mechanisms of skin aging. Ann NY Acad Sci 2007:1119: 40–50.
5.Harman D. The free radical theory of aging. Anti-oxid. Redox Signal.2003, 5, 557–561.
6.Harman D. Free radical theory of aging: an update: increasing the functional life span. Ann. N.Y. Acad. Sci. 2006, 1067, 10–21.
7.Borlon C, Weemaels G, Godard P et al. Expression profiling of senescent-associated genes in human dermis from young and old donors. Proof-of-concept study. Biogerontology. 2008, 9:197–208.
8.Lener T, Moll PR, Rinnerthaler M et al. Expression profiling of aging in the human skin. Exp Gerontol. 2006, 387–397.
9.Quan T, Shao Y, He T et al. Reduced expression of connective tissue growth factor (CTGF/CCN2), mediates collagen loss in chronologically-aged human skin. J Invest Dermatol. 2010, 130(2): 415–424.
10.Boraldi F, Bini L, Liberatori S et al. Proteome analysis of dermal fibroblasts cultured in vitro from human healthy subjects of different ages. Proteomics. 2003, 3, 917–929.
11.Perluigi M, Di Domenico F, Blarzino C et al. Effects of UVB-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: a proteomic approach. Proteome Sci. 2010 Mar 18;8:13.
12.Gromov P, Skovgaard GL, Palsdottir H et al. Protein Profiling of the Human Epidermis from the Elderly Reveals Up-regulation of a Signature of Interferon- -induced Polypeptides That Includes anganese-superoxide Dismutase and the p85β Subunit of Phosphatidylinositol 3-Kinase. Mol Cell Proteomics. 2003, 2(2):70-84.
13.Laimer M, Kocher T, Chiocchetti A et al. Proteomic profiling reveals a catalogue of new candidate proteins for human skin aging. Exp Dermatol. 2010 Oct;19(10):912-8.
14.Uitto. The role of elastin and collagen in cutaneous aging: intrinsic aging versus photoexposure. J Drugs Dermatol. 2008 Feb;7(2 Suppl):s12-6.
15.Berdyyeva TK, Woodworth CD, Sokolov I. Human epithelial cells increase their rigidity with ageing in vitro: direct measurements. Phys. Med. Biol. 2005, 50:81–92.
16.Sokolov I, Iyer S, Woodworth CD. Recovery of elasticity of aged human epithelial cells in vitro. Nanomedicine. 2006 Mar;2(1):31-6.
17.Clarkson E, Costa CF, Machesky LM. Congenital myopathies: diseases of the actin cytoskeleton. J Pathol. 2004 Nov;204(4):407-17. Review.
18. Li P, Gao XH, Chen HD et al. Localization of haptoglobin in normal human skin and some skin diseases. Int J Dermatol. 2005 Apr;44(4):280-4.
19.Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr. 2004 Sep;92(3):347-55.
20.Theilgaard-Monch K, Jacobsen LC, Nielsen MJ, et al. Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation. Blood 2006;108:353–61.
21.Arredouani M, Matthijs P, Van Hoeyveld E, et al. Hemoglobin directly affects T cells and suppresses T helper cell type 2 cytokine release. Immunology 2003;108:144–51.
22.Asleh R, Levy AP. In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease. Vasc Health Risk Manag. 2005;1(1):19-28.
23.Sadrzadeh SM, Bozorgmehr J. Haptoglobin phenotypes in health and disorders. Am J Clin Pathol. 2004 Jun;121 Suppl:S97-104.
24.Papp M, Lakatos PL, Palatka K et al. Haptoglobin polymorphisms are associated with Crohn''s disease, disease behavior, and extraintestinal manifestations in Hungarian patients. Dig Dis Sci. 2007 May;52(5):1279-84.
25.Costa-Mallen P, Checkoway H, Zabeti A et al. The functional polymorphism of the hemoglobin-binding protein haptoglobin influences susceptibility to idiopathic Parkinson''s disease. Am J Med Genet B Neuropsychiatr Genet. 2008 Mar 5;147B(2):216-22.
26.Prentice AM, Ghattas H, Doherty C et al. Iron metabolism and malaria". Food Nutr Bull. 2007 Dec;28(4 Suppl):S524-39.
27.Fanciulli G, Delitala G. Growth hormone, menopause and ageing: no definite evidence for ‘rejuvenation’ with growth hormone. Hum Reprod Update. 2009 May-Jun;15(3):341-58..
28.Moreira LR, Miranda-Vilela AL, Silva IC et al. Antioxidant effect of haptoglobin phenotypes against DNA damage induced by hydrogen peroxide in human leukocytes. Genet Mol Res 2009;8: 284–90.
29. Ding J, Kopchick JJ. Plasma biomarkers of mouse aging. Age (Dordr). 2011 Sep;33(3):291-307.
30. Miura Y, Sato Y, Arai Y et al. Proteomic analysis of plasma proteins in Japanese semisuper centenarians. Exp Gerontol. 2011 Jan;46(1):81-5.
31.Valerio Napolioni, Paola Gianni, Francesco M. et al. Haptoglobin (HP) polymorphisms and human longevity: A cross-sectional association study in a Central Italy population Clinica Chimica Acta 412 (2011) 574–577.
32.Laimer M, Kocher T, Chiocchetti A et al. Proteomic profiling reveals a catalogue of new candidate proteins for human skin aging. Exp Dermatol. 2010 Oct;19(10):912-8.
33.Sun H., Yamamoto M., Mejillano M. et al. Gelsolin, a Multifunction Actin Regulatory Protein. J Biol Chem. 1999 Nov 19; 274 (47) :33179-82.
34.Yu F., Sun H., Janmey P. et al. Identification of a polyphosphoinositide - binding sequence in an actin monomer -binding domain of gelsolin. J Biol Chem. 1992 Jul 25; 267(21):14616-21.
35.Witke W, Sharpe A, Hartwig J et al. Hemostatic, Inflammatory, and Fibroblast Responses Are Blunted in Mice Lacking Gelsolin. Cell. 1995 Apr 7;81(1):41-51.
36.Koya R, Fujita H, Shimizu S et al. Gelsolin Inhibits Apoptosis by Blocking Mitochondrial Membrane Potential Loss and Cytochrome C Release. J Biol Chem. 2000 May 19;275(20):15343-9.
37.Kothakota S, Azuma T, Reinhard C et al. Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science. 1997 Oct 10;278(5336):294-8.
38.Kamada S, Kusano H, Fujita H et al. A cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolin. Proc Natl Acad Sci U S A. 1998 Jul 21;95
39.Ahn JS, Jang IS, Kim DI et al.Aging-associated increase of gelsolin for apoptosis resistance. Biochem Biophys Res Commun. 2003 Dec 26;312(4):1335-41.
40.Tanaka M, Mullauer L, Ogiso Y et al. Gelsolin: A candidate for suppressor of human bladder cancer. Cancer Res 1995;55:3228–3232.
41.Daiger SP, Schanfield MS, Cavalli-Sforza LL. Group-specific component (Gc) proteins bind vitamin D and 25-hydroxyvitamin D. Proc Natl Acad Sci U S A 1975;72:2076–80.
42.Van Baelen H, Bouillon R, De Moor P. Vitamin D-binding protein (Gc- globulin) binds actin. J Biol Chem 1980;255:2270–2.
43.Lee WM, Galbraith RM. The extracellular actin-scavenger system and actin toxicity. N Engl J Med 1992;326:1335–41.
44.Mc Leod JF, Kowalski MA, Haddad Jr JG. Interactions among serum vitamin D binding protein, monomeric actin, profilin, and profilactin. J Biol Chem 1989;264:1260–7
45.Dahl B, Schiodt FV, Ott P, et al. Plasma concentration of Gc-globulin is associated with organ dysfunction and sepsis after injury. Crit Care Med 2003;31:152–6.
46.Meier U, Gressner O, Lammert F, Gc-globulin: roles in response to injury. Clin Chem. 2006 Jul;52(7):1247-53.
47.Dahl B, Schiodt FV, Kiaer T et al. Serum Gc-globulin in the early course of multiple traumas. Crit Care Med 1998;26:285–9.
48.Dahl B, Schiodt FV, Nielsen M et al. Admission level of Gc-globulin predicts outcome after multiple trauma. Injury 1999;30:275–81.
49.Ena JM, Esteban C, Perez MD et al. Fatty acids bound to vitamin D-binding protein (DBP) from human and bovine sera. Biochem Int 1989;19:1–7.
50.Williams MH, Van Alstyne EL, Galbraith RM. Evidence of a novel association of unsaturated fatty acids with Gc (vitamin D-binding protein). Biochem Biophys Res Commun 1988;153:1019–24.
51.Gumireddy K, Reddy CD, Swamy N. Mitogen-activated protein kinase pathway mediates DBP-MAF-induced apoptosis in RAW 264.7 macrophages. J Cell Biochem 2003;90:87–96
52.Perez HD, Kelly E, Chenoweth D et al. Identification of the C5a des Arg cochemotaxin. Homology with vitamin D-binding protein (group-specific component globulin). J Clin Invest 1988;82:360–3.
53.Kew RR, Webster RO. Gc-globulin (vitamin D-binding protein) enhances the neutrophil chemotactic activity of C5a and C5a des Arg. J Clin Invest 1988;82:364–9.
54.McVoy LA, Kew RR. CD44 and annexin A2 mediate the C5a chemotactic cofactor function of the vitamin D binding protein. J Immunol 2005;175:4754–60.
55.Shtivelman, E, Cohen, FE, Bishop, JM: A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure. Proc Natl Acad Sci USA 1992 89: 5472–5476
56.Nie Z, Ning W, Amagai M et al. C-terminus of desmoyokin/AHNAK protein is responsible for its translocation between the nucleus and cytoplasm. J Invest Dermatol 2000 114: 1044–1049
57.Hohaus A, Person V, Behlke J et al. The carboxyl-terminal region of ahnak provides a link between cardiac L-type Ca+2 channels and the actin-based cytoskeleton. FASEB J 2002 16: 1205–1216
58.Benaud C, Gentil BJ, Assard N et al. AHNAK interaction with the annexin 2/S100A10 complex regulates cell membrane cytoarchitecture. J Cell Biol. 2004 Jan 5;164(1):133-44.
59.Gettins PG. Serpin structure, mechanism, and function. Chem Rev. 2002 Dec;102(12):4751-804.
60.Kushner, Mackiewicz A (1993). The acute phase response: an overview.. CRC Press. pp. 3–19.
61.Paczek L, Michalska W, Bartlomiejczyk I. Trypsin, elastase, plasmin and MMP-9 activity in the serum during the human ageing process. Age Ageing. 2008 May;37(3):318-23. Epub 2008 Mar 10.
62.Mohacsi A, Fulop T Jr, Kozlovszky B. Sera and leukocyte elastase-type protease and antiprotease activity in healthy and atherosclerotic subjects of various ages. J Gerontol. 1992 Sep;47(5):B154-8.
63.Chao J, Chen LM, Chai KX. Expression of kallikrein-binding protein and alpha 1-antitrypsin genes in response to sex hormones, growth, inflammation and hypertension. Agents Actions Suppl. 1992;38 ( Pt 1):174-81.
64.Santos-Gonzalez M, Gomez Diaz C, Navas P et al. Modifications of plasma proteome in long-lived rats fed on a coenzyme Q10-supplemented diet. Exp Gerontol. 2007 Aug;42(8):798-806.
65.Suwabe H, Serizawa A, Kajiwara H. Degenerative processes of elastic fibers in sun-protected and sun-exposed skin: immunoelectron microscopic observation of elastin, fibrillin-1, amyloid P component, lysozyme and alpha1-antitrypsin. Pathol Int. 1999 May; 49(5):391-402.
66.Hart F,Hlodan R, Langer T. Molecular chaperones in protein folding: The art of avoiding sticky situations. Trends Biochem. Sci. 1994, 19, 20-25.
67.Guimaraes AJ, Frases S, Gomez FJ et al. Monoclonal antibodies to heat shock protein 60 alter the pathogenesis of Histoplasma capsulatum. Infect. Immun. 2009, 77, 1357-1367.
68.Creagh EM, Sheehan D, Cotter TG. Heat shock proteins – modulators of apoptosis in tumor cells. Leukemia 2000, 14,111-1173.
69.He L, Lemasters JJ. Heat shock suppresses the permeability transition in rat liver mitochondria. J. Biol. Chem. 2003, 278, 16755–16760.
70.Ghosh J, Dohi T, Kang B et al. Hsp60 regulation of tumor cell apoptosis. J. Biol. Chem. 2008, 283, 5188–5194.
71.Kindas-Mu ‥ gge, I. and Trautinger, F. Increased expression of the 27 kD heat shock protein (hsp27) in in vitro differentiated normal human keratinocytes. Cell Growth Differ. 1994. 5, 777–781.
72.Trautinger F, Kindas-Mu ‥gge I, Dekrout B. et al. Expression of the 27-kDa heat shock protein in human epidermis and in epidermal neoplasms: an immunohistological study. Brit. J. Dermatol. 1995: 133, 194–202.
73.Kaur P, Welch WJ, Saklatvala J. Interleukin 1 and tumor necrosis factor increase phosphorylation of the small heat shock protein. Effect in fibroblasts, Hep G2 and U937 cells. FEBS Lett. 1989: 227, 175–178.
74.Kindas-Mu ‥gge I, Herbacek I, Jantschitsch C et al. Modification of growth and tumorigenicity in epidermal cell lines by DNA-mediated gene transfer of heat shock protein 27 kD (hsp27). Cell Growth Differ.1996: 7, 1167–1174.
75.Young-Hee Lee, Jung-Chang Lee, Hyun-Ju Moon et al. Differential effect of oxidative stress on the apoptosis of early and late passage human diploid fibroblasts: implication of heat shock protein 60. Cell Biochem Funct 2008; 26: 502–508.
76.Sedelnikova OA, Redon CE, Dickey JS et al. Role of oxidatively induced DNA lesions in human pathogenesis. Mutat Res. 2010; 704:152-159.
77.Juan Ding, John Kopchick. Plasma biomarkers of mouse aging. AGE. Volume 33, Number 3 (2011), 291-307
78.Wang W, Gou L, Xie G et al. Proteomic analysis of interstitial fluid in bone marrow identified that peroxiredoxin 2 regulates H2O2 level of bone marrow during aging. J Proteome Res. 2010 Aug 6;9(8):3812-9.
79.Olahova M, Taylor SR, Khazaipoul S et al. A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance. Proc Natl Acad Sci U S A. 2008 December 16; 105(50): 19839–19844.
80.Wondrak GT, Jacobson MK, Jacobson EL. Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection. Photochem Photobiol Sci 2006; 5: 215-37.
81.Vile GF, Tyrrell RM. UVA radiation-induced oxidative damage to lipids and proteins in vitro and in human skin fibroblasts is dependent on iron and singlet oxygen. Free Radic Biol Med 1995; 18: 721-30.
82. Guipaud O, Holler V, Buard V et al. Time-course analysis of mouse serum proteome changes following exposure of the skin to ionizing radiation. Proteomics. 2007 Nov;7(21):3992-4002.
83.Strange RC, Fryer AA. The glutathione S-transferases: influence of polymorphism on cancer susceptibility. IARC Sci Publ. 1999;(148):231-49.
84.Kellen E, Hemelt M, Broberg K et al. Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review. Am. J. Epidemiol. 2007; 65 (11): 1221–30.
85.Sekine I, Minna JD, Nishio Ket al. A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with lung cancer. J Thorac Oncol. 2006 Jan;1(1):31-7.
86.Boraldi F, Bini L, Liberatori S. Proteome analysis of dermal fibroblasts cultured in vitro from human healthy subjects of different ages. Proteomics. 2003 Jun;3(6):91
87.Khalkhali-Ellis Z. Maspin: the new frontier. Clin Cancer Res. 2006 Dec 15;12(24):7279-83.
88.Sager R, Sheng S, Pemberton P et al. Maspin: a tumor suppressing serpin. Curr. Top. Microbiol. Immunol. 1996; 213 (1): 51–64.
89.Lonardo F, Li X, Kaplun A, Soubani A et al. The natural tumor suppressor protein maspin and potential application in non small cell lung cancer. Curr. Pharm. Des. 2010; 16 (16): 1877–81.
90.Sager R, Sheng S, Pemberton P et al. Maspin. A tumor suppressing serpin. Adv. Exp. Med. Biol. 1997; 425: 77–88.
91.Lee H, Greeley GH, Englander EW. Age-associated changes in gene expression patterns in the duodenum and colon of rats. Mech Ageing Dev 2001;122:355–71.
92.Brian J. Nickoloff, Mark W. Lingen, Bey-Dih Chang, et al. Tumor suppressor maspin is up-regulated during keratinocyte senescence, exerting a paracrine antiangiogenic activity. Cancer Res. 2004 May 1;64(9):2956-61.
93.Eckhart L, Declercq W, Ban J et al. Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation. J Invest Dermatol. 2000 Dec; 115(6):1148-51.
94.Smith FJ, Irvine AD, Terron-Kwiatkowski A . Loss-of-function mutations in the gene encoding fi laggrin cause ichthyosis vulgaris. Nat Genet. 2006 Mar;38(3):337-42. Epub 2006 Jan 29.
95.Schuttelaar ML, Kerkhof M, Jonkman MF et al. Filaggrin mutations, atopic eczema, hay fever, and asthma in children. Allergy. 2009 Dec;64(12):1758-65.
96.Denecker G, Hoste E, Gilbert BCaspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol. 2007 Jun;9(6):666-74.
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