臺灣博碩士論文加值系統

室溫離子溶媒(Room temperature ionic liquids; RTIL)是完全由離子組成的液體。事實上， 離子溶媒可以在室溫或室溫以下(甚至低到-90℃)保持液體，容易製造且花費不貴。離子溶媒因為易於回收、不易燃、具有不揮發的性質，跟典型的分子性溶媒相較，離子溶媒是更環保有效的反應媒介。本研究計劃利用離子溶媒進行α-azidoketones及quinoline衍生物的合成研究。

Room temperature ionic liquids (RTIL) are liquids that are composed entirely of ions. In fact, ionic liquids can now be produced which remain liquid at room temperature and below (even as low as -90℃) and can be appeared to be undemanding and inexpensive to manufacture. Ionic liquids offer an attractive alterative to conventional organic liquids for clean synthesis, as they are recycling easily, lacking flammability, and possessing no vapour pressure effectively. Comparing with classical molecular solvents, the ionic liquids are environmentally benign reaction media. In this work, the application of ionic liquid to prepare α-azidoketones and quinoline derivatives will be demostrated and discussed.

中文摘要………………………………………………………………….…………..……1
英文摘要………….……………………………………………………………………... 2
第一章 總論………...…………………………………………………………………..3
第二章 各論………………………………………………………………….11
第一節 利用aryl ketones經HDNIB處理形成α-[(2,4-dinitrobenzene)
sulfonyl]oxy ketone，再與sodium azide在離子溶媒中進行反應合成α-azidoketones…………………………………………………..11
第二節 利用2-aminobenzophenones與aryl ketones，用Amberlyst 15®當路易士酸，在離子溶媒下進行Friedländer reaction合成 quinoline衍生物…………………………………………….....…15
第三章 結論….……….……………………………………………………..21
第四章 實驗部分…..………………………………………………………..23
第一節 儀器………………………………………………………………....23
第二節 各化合物的製備……………………………………………………24
參考文獻………………………………………………………………………46

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