臺灣博碩士論文加值系統

氫氧基磷灰石(HA)其擁有高度的生物相容性,凝固時泥狀物的ph值接近
人體,植入人體後可與骨骼組織形成鍵結,不引起毒性,不刺激組織,而且兼
具引導骨骼向內生長的能力等優點.然而大部份的生醫陶瓷皆具有脆性,不
易成型,低破壞性等缺點.由於金屬具有高比強度及優異生物相容性,因此
本研究希望利用兩者之優點,來製作一高強度及高生物相容性的複合材料,
並探討氫氧基磷灰石與金屬之反應性研究.本實驗的條件如下:(1)純金
屬.(2)HA體積佔5%.(3)HA體積佔10%.實驗結果顯示,由XRD圖得知,其HA體
積佔10%的試片,當燒結溫度在T1以下時,其HA相仍然存在,且隨著燒結溫度
的提高,HA的含量亦隨之減少.而由彎曲強度結果得知,純金屬的彎曲強度
值隨燒結溫度的提高而增加,且彎曲強度最大值約為P1.在HA體積佔5%的條
件下,彎曲強度的最大值發生在T2時,其值約為P2.在HA體積佔10%的條件
下,彎曲強度最大值發生在T3時,其值約為P3.而從金相觀察結果方面,在燒
結溫度為T4,T5,T6的這三組試片中,金屬顆粒並未完全燒結在一起,而在燒
結溫度T7,T8以上時,其金屬顆粒開始大量地燒結在一起,且顆粒與顆粒之
間開始形成類似頸部的接合形狀.

Many reports are now available of clinical results with
solid hydroxyapatite used for jaw augmentation,tooth
replacement,bone substitution and middle ear reconstruction.
Hydroxyapatite is a particularly attractive material for bone
and tooth implants because its chemical and crystallographic
properties closely resemble those of bone and tooth minerals,and
the sintered material has superior compatibility with these
tissues.The principal limitation of this material is that it is
brittle and weak,which restricts the clinical orthopaedic and
dental applications.Metal has received special attention,
primarily because of its high strength and high resistance to
fracture. The incorporation of metal into hydroxyapatite
material may enhance its mechanical properties and will not
affect its biocompatibility.Thus it is desirable to study the
hydroxyapatite-metal composite materials.In the present paper
sintering of hydroxyapatite and metal composite materials is
reported.