臺灣博碩士論文加值系統

PLA (Poly Lactic acid)具有無毒、生物可分解性與生物可相容性，但熱性質與機械性質較差，所以其應用範圍著實受到限制，而本研究先以MOI (2-Methacryloyloxyethyl Isocyanate)改質PLA，透過矽烷偶合劑之選擇來導入，再經由溶膠-凝膠法（Sol-gel）製成有機∕無機奈米混成材料，經FT-IR、29Si-NMR與13C-NMR來確定其反應機構，以TGA、DSC、HDT與MI來觀察改質前後熱性質差別，其Td-10%、Xc與Tm等熱性質，隨silica添加增加成比例上升，而MI值則變小， 再由拉力機與耐衝擊試驗來測試其機械性質，觀察經MOI改質後之韌性增加，而機械強度降低，但添加silica則反之，可透過silica添加量來控制改質後之韌性與機械強度，並由SEM圖觀察得知改質前後，與添加silica後之表面變化情形，其表面結構由MOI改質後變為孔洞狀，添加silica後使其粒子填入孔洞內，造成其韌性、力學性質與結晶性改變，最後利用靜電紡絲來研究奈米纖維紡絲的可行性。

PLA are used as biomedical materials because they are biodegradable, but the vast majority of biodegradable polymers in clinical use are composed of rather stiff materials that exhibit limited extendibility, weak mechanical strength and poor thermal stability, they are unsuitable for use in numerous applications. We modified PLA with 2-methacryloyloxy- ethyl isocyanate (MOI) to prepare ductile PLA materials. By utilizing the sol-gel process, novel PLA nanocomposites were further prepared with improved thermal stability and mechanical properties. The 10% thermal decomposition temperature for PLA modified with 5% MOI and contained 5-10% silica is 31-36oC higher than that of original pristine PLA. Elongation at break increases by 5-14 times when compared to neat PLA, while the tensile strength maintained at 30-40 MPa. These synthesized PLA nanocomposites can be applied as biomaterials with better mechanical and thermal properties.

中文摘要 I
ABSTRACT II
謝 誌 III
目 錄 V
表目錄 X
圖目錄 XI
第一章 緒論 1
1.1 前言 1
1.2 研究背景 3
第二章 文獻回顧 6
2.1.1 生物可分解性高分子聚乳酸(Poly Lactic acid；PLA)簡介 6
2.1.2 聚乳酸(Poly Lactic acid；PLA)之優勢 7
2.1.3 聚乳酸(Poly Lactic acid；PLA)之合成 9
2.2有機∕無機奈米混成材簡介 11
2.2.1有機粘土 11
2.2.2 溶凝膠法 13
2.2.3 POSS 14
2.2.4奈米碳管 15
2.3.1 二氧化矽(SiO2)之簡介 17
2.3.2 溶膠-凝膠法（Sol-gel）之進程發展 20
2.3.3 溶膠-凝膠法（Sol-gel）之定義 22
2.3.4 溶膠-凝膠法（Sol-gel）反應機構與因素 23
2.3.4.1含水量之影響 23
2.3.4.2 pH值之影響 24
2.3.4.3 溶劑之影響 26
2.3.4.4 溫度之影響 26
2.4實驗目的 26
第三章 實驗方法與步驟 28
3.1.1實驗藥品與原料 28
3.1.2使用檢測之儀器 29
3.1.2.1 傅立葉紅外線轉換光譜儀 (Fourier transform Infrared Spectroscopy，FT-IR)分析 29
3.1.2.2 超導核磁共振儀(nuclear magnetic resonance，NMR)分析 29
3.1.2.3 熱重量分析儀 (Thermogravimetric Analyzer，TGA) 30


3.1.2.4低溫調幅式示差掃描熱卡計(Low-Temperature-Modulate Differential Scanning Calorimeter，MDSC)分析 30
3.1.2.4 熱變形溫度 (Heat deflection temperature，HDT)測試分析 30
3.1.2.5 凝膠色譜分析儀 (Gel Permeation Chromatography，GPC)分析 31
3.1.2.6 萬能試驗拉力機 (universal testing machine)測試分析 31
3.1.2.7 熔融流動指數 (Melt Flow Index，MI) 分析 32
3.1.2.8 擺錘式衝擊 (Pendulum Impact Tester)試驗 32
3.1.2.9 X光繞射分析儀 (X-ray Diffraction, XRD)分析 32
3.1.2.10 掃瞄電子顯微鏡 (Scanning electron microscope，SEM) 33
3.1.2.12 電紡(Electrospinning)之分析 33
3.1.1. 改質實驗步驟 35


第四章 結果分析與討論 38
4.1 傅立葉轉換紅外線光譜儀 (Fourier transform Infrared Spectroscopy FT-IR)分析 38
4. 2 NMR（nuclear magnetic resonance）分析 48
4.3熱重量分析儀(Thermogravimetric Analyzer，TGA)分析 52
4.4 熱示差掃瞄卡量計（Differential Scanning Calorimeter，DSC）分析 55
4.4熱變形溫度測試分析 58
4.5凝膠色層分析儀(Gel Permeation Chromatography，GPC)分析 59
4.6 抗拉強度分析 61
4.7擺錘式衝擊試驗 64
4.8 PLA改質前後熔融流動指數 65
4.9 X-ray繞射分析 66
4.10 SEM分析 67
4.11 電紡(Electrospinning)之分析 71
結論 78
參考文獻 81

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