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研究生:王文郁
研究生(外文):Wen-Yu Wang
論文名稱:不同活動量社區老人其骨質密度代謝指標及體適能情形之探討
論文名稱(外文):Investigation of bone metabolic indices and physical fitness in different activity community old people
指導教授:李淑玲李淑玲引用關係
口試委員:蔡英美何應志
口試日期:2013-07-22
學位類別:碩士
校院名稱:中州科技大學
系所名稱:保健食品系
學門:農業科學學門
學類:食品科學類
論文種類:學術論文
論文出版年:2014
畢業學年度:101
語文別:中文
論文頁數:89
中文關鍵詞:骨質疏鬆症身體活動量骨質密度骨質代謝指標功能性體適能
外文關鍵詞:Osteoporosisphysical activitybone mineral densitybone metabolismfunctional fitness
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本研究以65歲以上社區老人做為研究對象(N=177),探討社區中不同運動量的老人其身體活動量對於骨質疏鬆代謝指標、骨質密度、功能性體適能及、健康相關生活品質問卷的差異性,以台灣老人身體活動量表(Physiccal Activity Scale for the Elderly,PASE)做為活動量分類依據(PASE分數大於125.9為高活動量者;67.6至125.9為中活動量者;小於67.6為低活動量者),每位受試者須完成PASE、健康生活品質(SF-36)問卷填寫、骨質密度檢測、血液採集及功能性體適能測驗,進行不同活動量之間骨質密度、骨質代謝指標、SF-36、功能性體適能之比較,統計分析採單因子變異係數進行檢定。研究結果發現三種不同活動量骨質密度(T值)結果為:高活動量(-1.84)、中活動量(-1.91)、低活動量(-2.41),三組之間並無顯著性差異,然而,高活動量與低活動兩組間比較(p=0.051)趨近於統計上顯著性差異(p<0.05),SF-36項目:生理總分、一般自覺健康、活力狀態、社會功能、角色限制-情緒,高活動量與低活動量呈現顯著性差異(p<00.5);功能性體適能顯示:下肢體前彎、平衡、上肢肌力、下肢肌力項目,高活動量組與低活動量組呈現顯著性差異(p<0.05),由以上結果顯示,老年人平時有較高身體活動量者,將可正面影響骨質密度、骨質代謝指標、生活品質及功能性體適能,達到促進健康生理效益。
關鍵字:骨質疏鬆症、身體活動量、骨質密度、骨質代謝指標、功能性體適能

The purpose ofthis study is toexplore the different activity levels of the elderly in different communities impact on their bone density geriatric metabolism and fitness situations.The experiments focused on the elderly over 65 in the communities in central Taiwan (N = 177). Physical activity in elderly Taiwanese scale (Physiccal Activity Scale for the Elderly, PASE is used) were as an activity basis (PASE score higher than 125.9 belongs to high activity levels; 67.6 to 125.9 belongs to middle amount of activity; less than 67.6 belongs to low activity).Each subject required to complete the PASE, healthy quality of life questionnaires (SF-36), bone density testing, blood collection and functional physical fitness test.The amount of bone density, bone metabolic markers, SF-36, and the functional fitness of different amount of activitity inelderly wasanalysised by one-way AVONA. The results showed that the amount of bone density in three different events (T value): high activity (-1.84), the middle activity level (-1.91), low activity (-2.41),and there were no significantly difference between groups.However, the bone density in high activity group was higher than in low activity group.High activity and low activity levels showed a significant difference in SF-36 project of physiology score, general health perception, vitality status, social functioning, role limitations – emotional(p<0.05).The above results showed that the elderly person with a high amount of physical activity have a positive impact on bone density,bone metabolic markers, quality of life and functional fitness.
Key Words :Osteoporosis, physical activity,bone mineral density,bone metabolism, functional fitness

中文摘要                    Ⅰ
英文摘要                  Ⅱ
誌謝                     Ⅲ
目錄                     Ⅳ
表目錄                    Ⅶ
圖目錄                    Ⅷ

第一章 緒論…….………………………………………………………..1
第一節 研究背景與動機……………………………………………...1
第二節 研究目的……………………………………………………...2
第三節 研究問題……………………………………………………...3
第四節 名詞解釋……………………………………………………...3
第五節 研究限制……………………………………………………...4
第二章 文獻回顧…………………………………………………….…..5
第一節 人體骨質的介紹………………………………………….…..5
一、骨質架構………………………………………………………5
二、骨質組成………………………………………………………5
三、骨質代謝………………………………………………….……5
第二節 骨質疏鬆介紹…………………………………………….7
一、骨質疏鬆定義………………………………………………….7
二、骨質疏鬆分類………………………………………………….7
三、骨質疏鬆影響因子…………………………………………..8
1.不可控制因子…………………………………………………..8
(1)年齡…………………………………………………………..8
(2)性別…………………………………………………………..9
(3)種族…………………………………………………………..9
2.可控制因子……………………………………………………10
(1)飲食…………………………………………………………10
(2)活動量………………………………………………………11
第三節 骨質代謝的偵測指標……………………………………….13
一、直接檢測……………………………………………………...13
二、T值……………………………………………………………14
三、生化檢驗…………………………………………………….15
1.骨質代謝生成指標分項敘述………………………………17
(1)骨鹼性磷酸酶……………………………………………17

(2)骨鈣素……………………………………………………17
(3)C型膠原蛋白延長胜肽………………………………….17
(4)N型膠原蛋白延長胜肽………………………………….18
2.骨質代謝指標………………………………………………18
(1)交互連結分子……………………………………………18
(2)骨膠原蛋白C端片段、N端片段.........18
(3) I型膠原蛋白羧基末端肽……………………………….19
(4)抗酒石酸磷酸酶…………………………………………20
第四節 老人骨質健康之概述……………………………………….21
第五節 身體活動量與骨質之相關性探討………………………….23
一、活動量對骨質密度之研究…………………………………...23
二、運動對骨質代謝指標之研究……………………………….24
三、老人參與運動對於骨質的影響……………………………..25
第三章 研究方法..............................26
一、研究對象............................26
二、實驗設計與架構.......................26
三、研究流程............................27
四、研究工具............................29

五、資料分析............................32
第四章 結果與討論.............................33
表一、WHO定義骨質密度之標準.....................15
表二、常用的骨質代謝生化指標.....................16
表三、受試者基本資料...........................33
表四、身體活動量,高、中、低組間,骨質密度與代謝指標分析…37
表五、身體活動量高、中、低組間SF-36問卷的結果…………………41
表六、老人身體活動量高、中、低組間功能性體適能的結果………44
圖一、骨質膠原蛋白代謝路徑圖……………………………………….19
圖二、實驗架構圖……………………………………………………….27
圖三、實驗流程圖………………………………………………………28

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