臺灣博碩士論文加值系統

光纖修飾金奈米生化感測器是使用定域化表面電漿共振原理，
使金奈米粒子吸收與散射光纖表面的漸逝波，進而增強光纖對折射率感測的靈敏度。為提升光纖感測器的靈敏度，不同研究團隊有不同的改善方式，在本研究中同時使用了兩種方式：(1)對光纖進行錐化，以及(2)在光纖表面修飾球狀金奈米。針對液體樣品折射率的量測，光纖拉伸錐化可改變數值孔徑、正歸化頻率與光傳播模態分布，此三項的變化有助於折射率作感測的能力增強。
在本論文中使用自組裝的電弧放電系統對多模光纖(core-400 μm 和cladding-430 μm )進行錐化拉伸，同時也在表面修飾球狀金奈米粒子。在兩種效應之下，隨著外界感測液體的折射率變化，對於光纖的光強度變化更加顯著，達到感測能力的雙重提升。錐形光纖的腰部半徑分別有300 μm與200 μm兩種，研究結果發現錐形光纖感測能力較均勻光纖佳，且對於較細的腰部半徑錐形光纖，其感測器能力較粗的腰部半徑錐形光纖為佳，此結果符合我們的預期。

A fiber biosensor modified by nano-gold particles is made according to the localized surface plasma resonance theorem. The nano-gold particles enhances the sensitivity of the sensor measuring the refractive index (RI) by absorbing and scattering the evanescent wave on the interface between the core and the liquid to be tested.
Different research teams have used different approaches to achieve the same goal. In this study, we pursue our goal by modification of the fiber with nano-gold particles. This fiber is either tapered or non-tapered in advance. Note that taper of the fiber may result in the variations of numerical aperture of the fiber, normalized frequency, and the path of propagating light.
In the practice of this work, we use an arc discharge system to pull and taper a multimode fiber (core: 400 μm and cladding: 430 μm, both in diameter) or simply remove the cladding. Afterwards, we modify the fiber with spherical nano-gold particles with a diameter of 15 nm. Consequently, when we measure refractive indices of different liquids with this tailored fiber, the light intensity variation with the refractive indices is enlarged.
When pull and taper of the abovementioned fiber yield diameters of 300 μm and 200 μm, the latter shows a better sensitivity that the former. Besides, they are both superior to the uniform fiber which is not tapered.
Keyword：nano-gold particle, refractive index, tapered fiber, evanescent wave and localized surface plasma resonance.

中文摘要…………………………………………………………………I
Abstract ………………………………………………………………II
目錄……………………………………………………………………III
圖表目錄 ………………………………………………………………VI

第一章 緒論……………………………………………………………1
1-1 研究背景……………………………………………………………1
1-1-1 光纖簡介…………………………………………………………1
1-1-2 光纖生物感測器…………………………………………………1
1-1-3 金奈米粒子簡介…………………………………………………2
1-1-4 電弧放電加工簡介………………………………………………2
1-2 研究動機與目的……………………………………………………3
1-3 本文簡介……………………………………………………………4

第二章 錐形光纖與金奈米表面電漿共振原理………………………5
2-1 光纖基本原理介紹…………………………………………………5
2-1-1 傳統光纖的基本構造……………………………………………5
2-1-2 光在光纖中傳播的原理…………………………………………6
2-1-3 光纖中的重要參數………………………………………………7
2-2 表面電漿共振原理…………………………………………………8
2-2-1 漸逝波 (Evanescent Wave)……………………………………8
2-2-2 Goos & Hanchen Shift…………………………………………9
2-2-3 表面電漿共振 (Surface Plasmon Resonance) ……………12
2-2-4 金屬奈米粒子吸收原理 ………………………………………18
2-3 錐形光纖
2-3-1 錐形光纖的數值孔徑 …………………………………………23
2-3-2 錐形光纖的傳輸原理 …………………………………………23

第三章 錐形光纖感測器製作與實驗方法……………………………26
3-1 引言 ………………………………………………………………26
3-2 自行組裝模組 ……………………………………………………26
3-2-1電弧放電控制系統組織架構……………………………………26
3-2-2感測系統儀器架設………………………………………………30
3-3 實驗流程 …………………………………………………………31

第四章 實驗結果與討論………………………………………………38
4-1 引言 ………………………………………………………………38
4-2 製作錐形光纖 ……………………………………………………38
4-2-1光纖錐化拉伸……………………………………………………38
4-2-2光纖端面研磨……………………………………………………40
4-3 修飾金奈米錐形光纖的光學特性 ………………………………41
4-4 修飾金奈米光纖錐化前後感測能力比較 ………………………42

第五章 結論與未來展望………………………………………………47
5-1 結論 ………………………………………………………………47
5-2 未來展望 …………………………………………………………48

參考文獻 ………………………………………………………………49

附錄1……………………………………………………………………52

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