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研究生:黃煌文
研究生(外文):Huang-Wen Huang
論文名稱:ComparisonbetweenNetworkComponentAnalysisandIndependentComponentAnalysis
論文名稱(外文):Comparison between Network Component Analysis and Independent Component Analysis
指導教授:黃郁芬黃郁芬引用關係
指導教授(外文):Yu-Fen Huang
學位類別:碩士
校院名稱:國立中正大學
系所名稱:統計科學所
學門:數學及統計學門
學類:統計學類
論文種類:學術論文
論文出版年:2007
畢業學年度:95
語文別:英文
論文頁數:43
中文關鍵詞:independent、entropy、nongaussian、kurtosis
外文關鍵詞:nongaussian、kurtosis、independent、entropy
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Network component analysis (NCA) and independent component analysis (ICA) both are the ways of redundancy reduction. These statistical methods are for transforming an observed multidimensional random vector into lowerdimension. In this thesis, we use two different algorithms for linear ICA: fast fixed-point algorithm and joint approximate diagonalization of eigenmatrices algorithm. We compare these three techniques that the ability of
reconstructing the hidden regulatory layers, via the simulation studies and a real data examples. We also investigate the sensitivity of the reconstructed signals to inaccuracies in the strength of network connectivity.
Network component analysis (NCA) and independent component analysis (ICA) both are the ways of redundancy reduction. These statistical methods are for transforming an observed multidimensional random vector into lowerdimension. In this thesis, we use two different algorithms for linear ICA: fast fixed-point algorithm and joint approximate diagonalization of eigenmatrices algorithm. We compare these three techniques that the ability of
reconstructing the hidden regulatory layers, via the simulation studies and a real data examples. We also investigate the sensitivity of the reconstructed signals to inaccuracies in the strength of network connectivity.
1 Introduction 1
2 Independent Component Analysis 2
2.1 Independent Component Analysis by Negentropy . . . . . . . 4
2.2 Independent Component Analysis by Kurtosis . . . . . . . . . 6
2.3 Fast Fixed-Point Algorithm . . . . . . . . . . . . . . . . . . . 8
2.3.1 The Algorithm for one unit . . . . . . . . . . . . . . . 8
2.3.2 The Algorithm for several units . . . . . . . . . . . . . 9
2.4 Joint Approximate Diagonalization of Eigen-matrices Algorithm 9
2.4.1 The Algorithm . . . . . . . . . . . . . . . . . . . . . . 10
3 Network Component Analysis 11
3.1 The Network Component Analysis Model . . . . . . . . . . . . 12
3.2 Criteria for NCA . . . . . . . . . . . . . . . . . . . . . . . . . 13
3.3 The Algorithm of NCA . . . . . . . . . . . . . . . . . . . . . . 17
4 Examples 18
4.1 Synthetic Data of Two Sources . . . . . . . . . . . . . . . . . 18
4.2 Synthetic Data of Three Sources . . . . . . . . . . . . . . . . . 20
4.3 Real Data of Three Sources . . . . . . . . . . . . . . . . . . . 22
5 Conclusion 23
1. K. C. Kao, Y. L. Yang, R. Boscolo, C. Sabatti, V. Roychowdhury, and J. C. Liao (2004), Transcriptome-based determination of multiple transcription regulator activities in Escherichia coli by using network component analysis,
Proceedings of the National Academy of Sciences (PNAS), 101, 641-646.
2. R. Boscolo, C. Sabatti, J. C. Liao, and Vwani P. Roychowdhury (2005), Reconstructing hidden regulatory layers by network component analysis: theory and application, IEEE Trans. Comput. Biol. Bioinf. in press
3. J. C. Liao, et al. (2003), Network component analysis: reconstruction of regulatory signals in biological systems, Proceedings of the National Academy of Sciences (PNAS), 100, 15522-15527.
4. L. M. Tran et al., and J. C. Liao. (2005), gNCA: A framework for determining transcription factor activity based on transcriptome: identifiability and numerical implementation, Metab. Engin, 7, 128-141.
5. R. Boscolo, C. Sabatti, J. C. Liao, and Vwani P. Roychowdhury (2005), A generalized framework for network component analysis, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2, 289-301.
6. Cardoso, J. F. (1999), High-order contrasts for independent component analysis, Neural Computation, 11, 157-192.
7. Hyvarinen and Oja, A. Hyvarinen and E. Oja. (1997), A fast fixed-point algorithm for independent component analysis, Neural Comput., 9, 1483-1492.
8. Hyvarinen A. (1997), Fast and robust fixed-point algorithms for independent component analysis, IEEE Transactions on Neural Networks, 10, 626-634.
9. J. F. Cardoso and A. Souloumiac (1993), Blind beamforming for non Gaussian signals, IEE-Proceedings-F, 140, 362-370.
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