臺灣博碩士論文加值系統

第一部份、我們研發出了一個新型人工感測劑 1，可自其可見光及螢光的光譜來偵測金屬離子。感測劑 1 特別對於汞和銅離子有優異的靈敏性及選擇性之偵測效果。在混合溶液 （二甲亞楓與水的體積比為 4：1） 中，此感測劑除了可藉由不同的顏色變化來作選擇性地辨識汞和銅離子之外，同時也能與其他金屬陽離子做區辨。除此之外，感測劑 1 會與汞離子可產生紫色螢光，而與銅離子則會產生強烈的藍色螢光。

第二部份、合成兩種具有肉眼辨識功能之旋光感測劑 1 和 2，並藉由可見光以及 1H NMR 光譜來檢驗它們對旋光性雙酸陰離子 (D 及 L 型天門冬胺酸離子，和 D 及 L 型蘋果酸離子) 的對掌選擇性之區辨能力。當感測劑 1 和 2 分別加入天門冬胺酸離子和蘋果酸離子的對掌異構物時，其溶液顏色有顯著變化可直接由肉眼區辨出來。因為顏色的區別性很大，所以感測劑 1 和 2 不只可以用來區辨 D 及 L 型天門冬胺酸離子，且可以用來區辨 D 及 L 型蘋果酸離子。除此之外，感測劑 1 對天門冬胺酸離子有極高的 D/L 選擇性 (Ka(D)/Ka(L) = 12.15)。

part 1. A new artificial receptor 1 was developed, and its chromogenic and fluorogenic behaviors toward various metal ions were investigated. Receptor 1 shows exclusively responses toward Hg2+ and Cu2+ ions. It selectively senses Hg2+ and Cu2+ ions through two different color changes in aqueous solution (DMSO/H2O = 4/1) and also distinguishes them from other metal ions. In addition, receptor 1 also exhibits pronounced enhancements of the fluorescence, which can visually be discernible by an orchid fluorescence in the presence of Hg2+ ions and a strong blue fluorescence in the presence of Cu2+ ions.

part 2. Two chiral colorimetric sensors, 1 and 2, were synthesized and characterized. Their enantioselective recognition for chiral dicarboxylic anions (D/L aspartate and D/L malate, ) was examined by UV-vis and 1H NMR spectroscopy. When the receptors 1 and 2 interact with enantiomers of aspartate or malate, respectively, the obvious different color changes are observed. Thus for distinct color changes, 1 and 2 can not only act as optical chemosensors for recognition of D-aspartate vs. L-aspartate but also for recognition of D-malate vs. L-malate. Besides that, the receptor 1 exhibited highly enantioselective binding for aspartate anions [KA(D) / KA(L) = 12.15].

第一部份
中文摘要
英文摘要
壹、緒論
貳、實驗部份
貳、一、測試儀器
貳、二、實驗試藥與溶劑
叁、實驗結果與討論
肆、結論
伍、合成步驟與光譜數據
陸、文獻資料

第二部份
中文摘要
英文摘要
壹、緒論
貳、實驗部份
貳、一、測試儀器
貳、二、實驗試藥與溶劑
叁、實驗結果與討論
肆、結論
伍、合成步驟與光譜數據
陸、文獻資料

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