臺灣博碩士論文加值系統

我們利用矽場效應電晶體進行非破壞性的偵測對甲基紅(para-methyl red)的光致異構變化。對甲基紅為一種光致異構物，如以365 nm UV光照射會導致從高能反式態(trans)到低能順式態(cis)的結構變化，而以450 nm可見光照射會導致從順式到反式的結構變化。順式或反式的結構變化會產生電子雲分佈的改變，導致分子的偶極矩產生變化。我們在真空，大氣與各種液態環境下做測試，並且發現在液態純水的環境下，此一結構轉換的重複性較其他環境中表現得更好，且結構改變所造成的電偶極矩改變量也較大。另外，以UV光照射3分鐘，對甲基紅可以被激發到順式的平衡態。此一順式態於室溫黑暗下回復到反式態的自然衰退時間約為112秒。在順式時如照射60秒可見光，回復至反式的時間可以大幅縮短為 3秒。
場效應電晶體平台是量測分子結構改變產生的電偶極距變化，因此不會對分子加以任何形式的外力。相較於其他的光學系統，為了測得分子結構，都需要施加探測光以致於對分子結構造成影響，場效應電晶體平台更能表現出分子狀態改變的本質。

We showed detection of the transition between cis and trans states of a para-methyl red using silicon field-effect-transistors. Para-methyl red is a photoisomerizable molecule: the transition from low-energy trans to high-energy cis states can be stimulated by irradiation of 365 nm UV light, and the reversed process can be accelerated by irradiation of 450 nm visible light. The structural change can produce a change in the electron cloud distribution, and hence a change in the molecular dipole moment, which can be detected by the field-effect-transistors. In this study, the photon-trigged structural transitions were conducted in vacuum, in the air and in various liquid conditions. It was found that in pure water the photon trigged molecule structural changes were most prominent and reproducible. It took about 3 minutes of UV irradiation to excite the molecules to the cis equilibrium state, and the spontaneous relaxation time from the cis equilibrium state to trans equilibrium state was found to be about 112 sec. It was also found that by irradiation of visible light for 60 sec, this relaxation process could be accelerated and shortened to 3 sec.
Since field-effect-transistors detect the molecular dipoles, and thus would not apply force of any kinds to the molecules under study. This is in contrast to the popularly used optical detection technologies in which the probe light may, to a certain extent, disturb the molecule structure. In view of that, our field-effect-transistor based detection method provides a unique approach to reveal the nature of the structural state transitions.

目錄
摘　要 vii
ABSTRACT ii
致謝 iv
目錄 vi
圖目錄 vii
第一章 前言 1
第二章 導論 2
2.1 場效應電晶體 2
2.2 矽場效應電晶體 3
2.2 光致異構物 5
2.3對甲基紅和場效應電晶體 11
第三章 實驗方法與流程 15
3.1 實驗藥品 15
3.2 實驗設備和裝置 16
3.3 實驗流程 21
3.4 修飾步驟 22
3.4 實驗步驟 23
第四章 結果與討論 26
4.1 APTES紅外光光譜分析 26
4.1 對甲基紅紫外光可見光光譜分析 27
4.1 修飾電性分析 28
4.2 偵測順式與反式對甲基紅 29
4.3順式對甲基紅於黑暗下緩解時間 37
4.4照射可見光對黑暗下緩解時間影響 39
第五章 結論 44
參考文獻 45

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