|
Andres, J.L., Fan, S., Turkel, G.J., Wang, J.A., Twu, N.F., Yuan, R.Q., Lamszus, K., Goldberg, I.D., Rosen, E.M., Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents. Oncogene 16, 2229 – 2241. (1998)
Arap, W., Knudsen, E., Sewell, D.A., Sidransky, D., Wang, J.Y., Huang, H.J., Cavenee W.K., Functional analysis of wild-type and malignant glioma derived CDKN2Ab alleles: Evidence for an RB-independent growth suppressive pathway. Oncogene 15, 2013 – 2020. (1997)
Bargonetti, J., Manfredi, J.J., Multiple roles of the tumor suppressor p53. Curr. Opin. Oncol. 14, 86 – 91. (2002)
Brugarolas, J, Chandrasekaran, C, Gordon, J.I., Beach, D., Jacks, T., Hannon G.J., Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377, 552 – 557. (1995)
Brune, B., von Knethen, A., Sandau, K.B., Nitric oxide (NO): an effector of apoptosis. Cell Death Differ. 6, 969 – 975. (1999)
Cayrol, C., Knibiehler M., Ducommun B., p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53- deficient cells. Corinne Cayrol, Martine Knibiehler and Bernard Ducommun. Oncogene 16, 311 – 320. (1998)
Chang, G.J., Wu, M.H., Wu, Y.C., Su, M.J., Electrophysiological mechanisms for antiarrhythmic efficacy and positive inotropy of liriodenine, a natural aporphine alkaloid from Fissistigma glaucescens. Br. J. Pharmacol. 118, 1571 – 1583. (1996)
Chassot, A.A., Lossaint G., Turchi L., Meneguzzi G., Fisher D., Ponzio G., Dulic V., Confluence-induced cell cycle exit involves pre-mitotic CDK inhibition by p27(Kip1) and cyclin D1 downregulation. Cell cycle 7, 2038 – 2046. (2008)
Chen, Y.C., Lin-Shiau, S.Y. and Lin, J.K., Involvement of reactive oxygen species and caspase 3 activation in arsenite induce apoptosis. J Cell Physiol. 177, 324 – 333. (1998)
Chen, J., Jackson, P. K., Kirschner, M.W., Dutta, A., Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature 374, 386 – 388. (1995)
Choi, H.J., Lim, do Y., Park, J.H., Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells. BMC Gastroenterology 9, 39 – 50. (2009)
Datto, M.B., Yu, Y., Wang, X-F., Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter. J. Biol. Chem. 270, 28623 – 28628. (1995)
Deep, G., Singh, R.P., Agarwal, C., Kroll, D.J., Agarwal, R., Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin. Oncogene 25, 1053 – 1069. (2006)
el-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin,D., Mercer,W. E., Kinzler, K.W., Vogelstein, B., WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817 – 825. (1993)
el-Deiry, W.S., Harper, J.W., O’Connor, P.M., Velculescu, V.E., Canman, C.E., Jackman, J., Pietenpol, J.A., Burrell, M., Hill, D.E., Wang, Y. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res 54, 1169 – 1174. (1994)
Deng, C., Zhang, P., Harper, J.W., Elledge, S.J., Leder, P., Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82, 675 – 684. (1995)
Dulic, V., Kaufmann, W., Wilson, S., Tlsty, T., Lees, E., Harper, W., Elledge, S., Reed, S., p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 75, 1013 – 1023. (1994)
Elledge, S.J., Cell cycle checkpoints: preventing an identity crisis. Science 274, 1664 – 72. (1996)
Fero, M.L., Rivkin, M., Tasch, M., Porter, P., Carow, C.E., Firpo, E., Polyak, K., Tsai, L.H., Broudy, V., Perlmutter, R.M., Kaushansky, K., Roberts, J.M., A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell 85, 733 – 744. (1996)
Firth, L.C., Baker, N.E., Extracellular signals responsible for spatially regulated proliferation in the differentiating Drosophila eye. Dev Cell 8, 541 – 551. (2005)
Gartel, A.L., Tyner, A.L., Transcriptional regulation of the p21(WAF1/CIP1)Gene. Experimental Cell Research 246, 280 – 289. (1999)
Geller, D.A, Billiar, T.R., Molecular biology of nitric oxide synthases. Cancer Metastasis Rev. 17, 7 – 23. (1998)
Giaccia, A.J., Kastan, M.B., The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12, 2973 – 2983. (1998)
Goodman, J.E., Hofseth, L.J., Hussain, S.P., Harris, C.C., Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease. Environ. Mol. Mutagen. 44, 3 – 9. (2004)
Harper, J.W., Adami, G..R., Wei, N., Keyomarsi, K., Elledge, S.J., The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805 – 816. (1993)
Harper, J.W., Elledge, S. J., Keyomarsi, K.,Dynlacht, B., Tsai, L. H., Zhang, P., Dobrowolski, S., Bai, C., Connell-Crowley, L., Swindell, E., Fox, M. P., Wei. N. Inhibition of cyclin-dependent kinases by p21. Mol. Biol. Cell 6, 387 – 400. (1995)
Haupt, S., di Agostino, S., Mizrahi, I., Alsheich-Bartok, O., Voorhoeve, M., Damalas, A., Blandino, G., Haupt, Y., Leukemia Protein is Required for Gain of Function by Mutant p53. Cancer Res. 69, 4818 – 4826. (2009)
He, G., Siddik, Z. H., Huang, Z., Wang, R., Koomen, J., Kobayashi, R., Khokhar, A. R. and Kuang, J., Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities. Oncogene 24, 2929 – 2943. (2005)
Hofseth, L.J., Saito, S., Hussain, S.P., Espey, M.G., Miranda, K.M., Araki, Y., Jhappan, C., Higashimoto, Y., He, P., Linke, S.P., Quezado, M.M., Zurer, I., Rotter, V., Wink, D.A., Appella, E., Harris, C.C., Nitric oxide induced cellular stress and p53
activation in chronic inflammation. Proc. Nat. Acad. Sci. USA 100, 143 – 148. (2003)
Holy, J., Lamont, G., Perkins, E. Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine. BMC Cell Biol. 7, 13 – 25. (2006)
Hsieh, T.J., Liu, T.Z., Chern, C.L., Tsao, D.A., Lu, F.J., Syu, Y.H., Hsieh, P.Y., Hu, H.S., Chang, T.T., Chen, C.H., Liriodenine inhibits the proliferation of human hepatoma cell lines by blocking cell cycle progression and nitric oxide-mediated activation of p53 expression. Food Chem. Toxicol. 43, 1117 – 1126. (2005)
Hsu, S.P., Ho, P.Y., Juan, S.H., Liang, Y.C., Lee, W.S., Progesterone inhibits human endothelial cell proliferation through a p53-dependent pathway. Cell Mol. Life Sci. 65, 3839 – 50. (2008)
Hufford, C.D., Sharma, A.S., Oguntimein, B.O., Antibacterial and antifungal activity of liriodenine and related oxoaporphine alkaloids. J. Pharm. Sci. 69, 1180 – 1183. (1980)
Igata, M., Motoshima, H., Tsuruzoe, K., Kojima, K., Matsumura, T., Kondo, T., Taguchi, T., Nakamaru, K., Yano, M., Kukidome, D., Matsumoto, K., Toyonaga, T., Asano, T., Nishikawa, T., Araki, E., Adenosine monophosphate- activated protein kinase suppresses vascular smooth muscle cell proliferation through the inhibition of cell cycle progression. Circ. Res. 97, 837 – 844. (2005)
Jemal, A., Siegel, R., Ward, E., Hao, Y., Xu, J., Murray, T., Thun, M.J., Cancer statistics, CA Cancer J Clin 58, 71 – 96. (2008)
Jemal, A., Siegel, R., Ward, E., Hao, Y., Xu, J., Thun, M.J., Cancer statistics, 2009. CA Cancer J Clin 59, 225 – 249. (2009)
Johnson, P.F. Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors. J.Cell Sci. 118, 2545 – 2555. (2005)
Khan, M.R., Kihara, M., Omoloso, A.D. Antimicrobial activity of Michelia champaca. Fitoterapia 73, 744 – 748. (2002)
Kiang, L., Heichinger, C., Watt, S., Bähler, J. Nurse P. Cyclin-dependent kinase inhibits reinitiation of a normal S-phase program during G2 in fission yeast. Mol. Cell. Biol. 29, 4025 – 4032. (2009)
Kim, P.K., Zamora, R., Petrosko, P., Billiar, T.R. The regulatory role of nitric oxide in apoptosis. Int. Immunopharmacol. 1, 1421 – 1441. (2001)
Kiyokawa, H., Kineman, R.D., Manova-Todorova, K.O., Soares, V.C., Hoffman, E.S., Ono, M., Khanam, D., Hayday, A.C., Frohman, L.A., Koff, A. Enhanced growth of mice lacking the cyclindependent kinase inhibitor function of p27Kip1. Cell 85, 721 – 732. (1996)
Lane, M.E, Sauer, K., Wallace, K., Jan, Y.N., Lehner, C.F., Vaessin, H. Dacapo, a cyclin- dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell 87, 1225 – 1235. (1996)
Lecanda, J., Ganapathy, V., D'Aquino-Ardalan, C., Evans, B., Cadacio, C., Ayala, A., Gold, L.I. TGF beta prevents proteasomal degradation of the cyclin-dependent kinase inhibitor p27kip1 for cell cycle arrest. Cell Cycle. 8, 742 – 56. (2009)
Levine, A.J. p53, the cellular gatekeeper for growth and division. Cell 88, 323 – 331. (1997)
Lowe, S.W., Ruley, H.E., Jacks, T., Housman, D.E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74, 957 – 967. (1993)
Luo, Y., Hurwitz, J., Massague, J. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Nature 375, 159 – 161. (1995)
Maekawa, H., Iwabuchi, K., Nagaoka, I., Watanabe, H., Kamano, T., Tsurumaru, M. Activated peritoneal macrophages inhibit the proliferation of rat ascites hepatoma AH-130 cells via the production of tumor necrosis factor-a and nitric oxide. Inflamm. Res. 49, 541 – 547. (2000)
Mahyar-Roemer, M., Fritzsche, C., Wagner, S., Laue, M., Roemer, K. Mitochondrial p53 levels parallel total p53 levels independent of stress response in human colorectal carcinoma and glioblastoma cells. Oncogene 23, 6226 – 6236. (2004)
Matsui, T., Omura, K., Kawakami, K., Morita, S., Sakamoto, J. Genotype of thymidylate synthase likely to affect efficacy of adjuvant 5-FU based chemotherapy in colon cancer. Oncol. Rep. 16, 1111 – 1115. (2006)
Mazzanti, R., Platini, F., Bottini, C., Fantappiè, O., Solazzo, M., Tessitore, L. Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line. Biochem Pharmacol. 78, 21 – 32. (2009)
Messmer, U.K., Brune, B. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. Biochem. J. 319, 299 – 305. (1996)
Mitra, P., Ghule, P.N., van der Deen, M., Medina, R., Xie, R.L., Holmes, W.F., Ye, X., Nakayama, K.I., Harper, J.W., Stein, J.L., Stein, G.S., van Wijnen, A.J. CDK Inhibitors Selectively Diminish Cell Cycle Controlled Activation of the Histone H4 Gene Promoter by p220NPAT and HiNF-P. J. Cell. Physiol. 219, 438 – 48. (2009)
Mullany, L.K., Nelsen, C.J., Hanse, E.A., Goggin, M.M., Anttila, C.K., Peterson, M., Bitterman, P.B., Raghavan, A., Crary, G.S., Albrecht, J.H. Akt-mediated liver growth promotes induction of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest. J. Biol. Chem. 282, 21244 – 21252. (2007)
Murray, A.W. Recycling the cell cycle: cyclins revisited. Cell 116, 221 – 234. (2004)
Musgrove, E.A., Davison E.A., Ormandy C.J. Role of the CDK inhibitor p27 (Kip1) in mammary development and carcinogenesis: insights from knockout mice. J. Mammary Gland Biol. Neoplasia. 9, 55 – 66. (2004)
Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I., Loh, D.Y., Nakayama, K. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85, 707 – 720. (1996)
Nguyen, H., Gitig, D.M., Koff, A. Cell-free degradation of p27Kip1, a G1-cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome. Mol. Cell. Biol. 19, 1190 – 1201. (1999)
Niculescu, A.B. 3rd, Chen, X., Smeets, M., Hengst, L., Prives, C. and Reed, S.I. Effects of p21 (Cip1/WAF1) at both the G1/S and the G2/M cell cycle transitions：pRb is a critcal determinant in blocking DNA replication and in preventing endoreduplication. Mol. Cell. Biol. 18, 629 – 643. (1998)
Nissanka, A.P., Karunaratne, V., Bandara, B.M., Kumar, V., Nakanishi, T., Nishi, M., Inada, A., Tillekeratne, L.M., Wijesundara, D.S., Gunatilaka, A.A. Antimicrobial alkaloids from Zanthoxylum tetraspermum and caudatum. Phytochemistry 56, 857 – 861. (2001)
Nozaka, T., Watanabe, F., Tadaki, S., Ishino, M., Morimoto, I., Kunitomo, J., Ishii, H., Natori, S. Mutagenicity of isoquinoline alkaloids, especially of the aporphine type. Mutat. Res. 240, 267 – 279. (1990)
Oehler, C., Ciernik, I.F. Radiation therapy and combined modality treatment of gastrointestinal carcinomas. Cancer Treat. Rev. 32, 119 – 138. (2006)
Ogryzko, V.V., Wong, P., Howard, B.H. WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases. Mol. Cell. Biol. 17, 4877 – 4882. (1997)
Ogura, M., Cordell, G.A., Farnsworth, N.R. Anticancer sesquiterpene lactones of Michelia compressa (Magnoliaceae). Phytochemistry 17, 957 – 961. (1978)
Perner, A., Andresen, L., Normark, M., Rask-Madsen, J. Constitutive expression of inducible nitric oxide synthase in the normal human colonic epithelium. Scand J Gastroenterol. 37, 944 – 948. (2002)
Poon, M.A., Oconnell, M.J., Moertel, C.G., Wieand, H.S., Cullinan, S.A., Everson, L.K., Krook J.E., Mailliard J.A., Laurie J.A., Tschetter L.K. Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. J. Clin. Oncol. 7, 1407 – 18. (1989)
Poon, M.A., Oconnell, M.J., Wieand, H.S., Krook, J.E., Gerstner, J.B., Tschetter, L.K. Biochemical modulation of fluorouracil with leucovorin: confirmatory evidenceevidence of improved therapeutic efficacy in advanced colorectal cancer. J. Clin. Oncol. 9, 1967 – 72. (1991)
Prives, C. Signaling to p53: breaking the MDM2-p53 circuit. Cell 95, 5 – 8. (1998)
Pyo, M.K., Yun-Choi, H.S., Hong, Y.J. Antiplatelet activities of aporphine alkaloids isolated from leaves of Magnolia obovata. Planta Med. 69, 267 – 269. (2003)
Ramachandran, V., Matzkies, M., Dienemann, A., Sprenger, F. Cyclin a degradation employs preferentially used lysines and a cyclin box function other than cdk1 binding. Cell Cycle 6, 171 – 181. (2007)
Reis, T., Edgar, B.A. Negative regulation of dE2F1 by cyclin dependent kinases controls cell cycle timing. Cell 117, 253 – 264. (2004)
Renaudo, A., Watry, V., Chassot, A.A., Ponzio, G., Ehrenfeld, J., Soriani, O. Inhibition of tumor cell proliferation by sigma ligands is associated with K+ Channel inhibition and p27kip1 accumulation. J. Pharmacol. Exp. Ther. 311, 1105 – 1114. (2004)
Ren, Z., Kar, S., Wang, Z., Wang, M., Saavedra, J.E., Carr, B., JS-K. a novel non-ionic diazeniumdiolate derivative, inhibits Hep 3B hepatoma cell growth and induces c-Jun phosphorylation via multiple MAP kinase pathways. J. Cell Physiol. 197, 426 – 434. (2003)
Roy, S., Gu, M., Ramasamy, K., Singh, R.P., Agarwal, C., Siriwardana, S., Sclafani, R.A., Agarwal, R. p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer. Cancer Res. 69(3), 1166 – 1173. (2009)
Sanchez-Margalet, V., Gonzalez-Yang, C., Najib, S. Pancreastatin, a chromogranin A-derived peptide, inhibits DNA and protein synthesis by producing nitric oxide in HTCrat hepatoma cells. J. Hepatology 30, 80 – 85. (2001)
Satomi, Y., Nishino, H. Implication of mitogen-activated protein kinase in the induction of G1 cell cycle arrest and gadd45 expression by the carotenoid fucoxanthin in human cancer cells. Biochim. Biophys. Acta. 1790, 260 – 266. (2009)
Schwartz, G.K., Shah, M.A. Targeting the cell cycle: a new approach to cancer therapy. J Clin Oncol 23(36), 9408 – 9421. (2005)
Sgambato, A., Cittadini, A., Faraglia, B. Weinstein IB.Multiple functions of p27Kip1 and its alterations in tumor cells: a review. J. Cell. Physiol. 183, 18 – 27 (2000)
Shah, J.V., Cleveland D.W. Waiting for anaphase: Mad2 and the spindle assembly checkpoint. Cell 103, 997 – 1000. (2000)
Sheaff, R.J., Groudine, M., Gordon, M., Roberts, J.M. Clurman B.E. Cyclin E-CDK2 is a regulator of p27Kip1. Genes Dev. 11, 1464 – 1478. (1997)
Sheng, Y. L., Shih, W. C., Fuh, J. P. A New Variety from Taiwan: Michelia compressa var. lanyuensis (Magnoliaceae). 臺灣林產科學 15(4), 521 – 524. (2000)
Sodha, N.R., Clements, R.T., Sellke, F.W. Vascular changes after cardiac surgery: role of NOS, COX, kinases, and growth factors. Front Biosci. 14, 689 – 698. (2009)
Soria, G., Speroni, J., Podhajcer, O.L., Prives, C., Gottifredi, V. p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation. J. Cell Sci. 121, 3271 – 3282 (2008)
Stein, G.S., van Wijnen, A.J., Stein, J.L., Lian, J.B., Montecino, M., Zaidi, S.K., Braastad, C. An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition. J. Cell. Physiol. 209, 706 – 710 (2006)
Sukhanova, M.J., Du, W. Control of cell cycle entry and exiting from the second mitotic wave in the Drosophila developing eye. BMC Dev. Biol. 8, 7 – 16. (2008)
Sun, D., Ren, H., Oertel, M., Sellers, R.S., Shafritz, D.A., Zhu, L. Inactivation of p27Kip1 promotes chemical mouse liver tumorigenesis in the resistant strain C57BL/6J. Mol. Carcinog. 47(1), 47 – 55. (2008)
Toyoshima, H., Hunter, T. P27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78, 67 – 74. (1994)
Vickers, A. Botanical medicines for the treatment of cancer: rationale, overview of current data, and methodological considerations for phase I and II trials. Cancer Invest. 20, 1069 – 1079. (2002)
Waldman, T., Kinzler, K.W., Vogelstein, B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55, 5187 – 5190. (1995).
Wang, C.Z., Li, X.L., Wang, Q.F., Mehendale, S.R., Fishbein, A.B., Han, A.H., Sun, S., Yuan, C.S. The mitochondrial pathway is involved in American ginseng-induced apoptosis of SW-480 colon cancer cells. Oncol. Rep. 21(3), 577 – 584. (2009)
Wink, D.A., Vodovotz, Y., Laval, J., Laval, F., Dewhirst, M.W., Mitchell, J.B., The multifaceted roles of nitric oxide in cancer. Carcinogenesis 19, 711 – 721. (1998)
Woo, S.H., Reynolds, M.C., Sun, N.J., Cassady, J.M., Snapka, R.M., Inhibition of topoisomerase II by liriodenine. Biochem. Pharmacol. 54, 467 – 473. (1997)
Wu, H., Yang, F., Cui, S., Qin, Y., Liu, J., Zhang, Y. Hematopoietic effect of fractions from the enzymedigested colla corii asini on mice with 5-fluorouracil induced anemia. Am. J. Chin. Med. 35, 853 – 866. (2007)
Yagihashi, N., Kasajima, H., Sugai, S., Matsumoto, K., Ebina, Y., Morita, T., Murakami, T., Yagihashi, S. Increased in situ expression of nitric oxide synthase in human colorectal cancer. Virch. Arch. 436, 109 – 114. (2000)
Yamasaki, M., Kang, H.R., Homer, R.J., Chapoval, S.P., Cho, S.J., Lee, B.J., Elias, J.A., Lee, C.G.. P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway. Am. J. Respir. Cell Mol. Biol. 38, 346 – 353. (2008)
Yerushalmi, H.F., Besselsen, D.G., Ignatenko, N.A., Blohm-Mangone, K.A., Padilla- Torres, J.L., Stringer, D.E., Cui H., Holubec H., Payne C.M., Gerner E.W. The role of NO synthases in argininedependent small intestinal and colonic carcinogenesis. Mol. Carcinogen. 45, 93 – 105. (2006)
Zhang M., Yang H. Negative growth regulators of the cell cycle machinery and cancer. Pathophysiology xxx, xxx – xxx. Review (2009)
|