臺灣博碩士論文加值系統

審定書 ii
碩士論文電子檔案上網授權書 iii
臺北醫學大學電子暨紙本學位論文書目同意公開申請書 iv
臺北醫學大學學位考試保密同意簽到表 v
誌 謝 vi
目錄 viii
表目錄 x
圖目錄 xi
論 文 摘 要 xii
Abstract xiv
第一章 緒論 1
第二章 文獻探討 3
2.1 呼吸器脫離程序 3
2.2 呼吸器脫離的評估 5
2.3 呼吸器脫離指標(weaning indices) 7
2.4 類神經網路 10
2.4.1 類神經網路的原理 10
2.4.2 類神經網路於臨床上的運用 13
2.5 影響呼吸器脫離的相關因子 15
第三章 研究材料與方法 19
3.1 實驗設計 19
3.1.1 預測模型建立的收案流程 19
3.1.2 特徵選擇(feature selection) 22
3.1.3 類神經網路架構 23
3.1.4 前瞻性驗證的收案流程 25
3.2 統計方法 28
第四章 結果 29
4.1 以回顧性收案病患資料建立類神經網路預測模型 29
4.1.1 回顧性收案病患分析 29
4.1.2 利用5倍交叉驗證尋找最佳隱藏層神經元個數 32
4.2 以前瞻性收案病患資料測試類神經網路模型 34
4.2.1 前瞻性收案病患分析 34
4.2.2 以前瞻性個案驗證類神經網路預測模型 36
4.3 匯集前瞻性與回顧性個案資料後的類神經網路模組再驗證 37
4.3.1 分析建立的預測模型其預測能力不良的原因 37
4.3.2 匯集兩階段收案病患的資料分析 41
4.3.3 匯集兩階段收案病患的資料集後進行類神經網路模組的再驗證 43
第五章 討論與結論 47
5.1 討論 47
5.1.1 研究病患族群分析 47
5.1.2 分析前瞻性驗證結果不佳的原因 48
5.1.3 以壓力支持型通氣模式作為自發性呼吸測試的原因 50
5.1.4 與過去相關研究之比較 52
5.2 研究限制 53
5.3 結論與未來展望 54
參考資料 55
附錄
附錄1：第一組5倍交叉驗證測驗組與訓練組各項類神經網路輸入參數比較 63
附錄2：第二組5倍交叉驗證測驗組與訓練組各項類神經網路輸入參數比較 64
附錄3：第三組5倍交叉驗證測驗組與訓練組各項類神經網路輸入參數比較 65
附錄4：第四組5倍交叉驗證測驗組與訓練組各項類神經網路輸入參數比較 66
附錄5：第五組5倍交叉驗證測驗組與訓練組各項類神經網路輸入參數比較 67

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