臺灣博碩士論文加值系統

目的：探討清酒粕蛋白補充劑 (Sake Protein supplementation, SP) 對於本實驗所設計之肌力訓練 (Power Exercise Training, PET) 計畫改善身體疲勞和增強運動表現效果以及產品定位之研究。方法：本實驗透過小鼠平台針對 SP 對於小鼠運動表現以及運動疲勞相關之血液生化指標之影響。隨機分成三組 (每組 n=8)：(1) 空白對照組 (Vehicle)、(2) 肌力訓練組 (PET) 以及 (3) 餵食清酒粕蛋白補充劑合併肌力訓練組 (PET+SP)。SP 經口管餵食方式連續餵食 4 週後，進行下列測試包括：前肢抓力 (肌力測試)、5% 負重游泳力竭時間 (有氧耐力) 以及運動 15 分鐘後血液中疲勞指標血乳酸 (Lactate)、血氨 (Ammonia) 以及肌肉損傷指標 (Creatine Kinase,CK) 之變化，測試期間仍繼續補充 SP。收集之數據以 SAS 統計軟體進行單因子變異數分析，並以 P<0.05 表示具有統計上意義。結果：4 週的 PET 計畫顯著增加握力和游泳運動耐力表現和降低副睾脂肪 (EFP) 的重量和面積。PET 計畫下合併補充 SP 在運動後 15 分鐘測試的血液生化表現部分，Lactate、Ammonia 和 CK 活性顯著下降，在臨床血液生化值的部分，天門冬胺酸轉胺酶 (AST)、丙胺酸轉胺酶 (ALT)、肌酸酐 (Creatinine) 和尿酸 (UA) 均顯著下降。結論：研究成果證實在 PET 計畫下可以提升運動表現和調控身體組成，而 PET 計畫下補充 SP 具有抗疲勞之功效及改善生化概況。在產品定位的部分，本研究之 SP 經由後續加工程序成本可能不貴，而許多國內青少年運動員因經濟能力而無法額外補充進口的乳清蛋白相關營養補充品。因此若能提供國內青年選手使用，勢必能提高其未來之發展。

關鍵字：清酒粕、肌力訓練、運動表現、抗疲勞、產品定位

Purpose: In this study, we designed a power exercise training (PET) program with a mouse model based on a strength and conditional training protocol for humans. We tested the effect of supplementation with functional branched-chain amino acid (BCAA)-rich sake protein (SP) to determine whether the supplement had a synergistic effect during PET and enhanced athletic performance and resistance to fatigue and Product Positioning Research. Methods: Male ICR mice were divided into 3 groups (n = 8 per group) for 4-week treatment: vehicle , PET and PET groups with SP supplementation (PET+SP). Exercise performance was evaluated by forelimb grip strength and exhaustive swimming time as well as changes in body composition and anti-fatigue activity levels of serum lactate, ammonia, glucose, and creatine kinase (CK) after a 15-min swimming exercise. The biochemical parameters were measured at the end of the experiment. Results: 4-week PET significantly increased grip strength and exhaustive swimming time and decreased epididymal fat pad (EFP) weight and area. PET+SP supplementation significantly decreased serum lactate, ammonia and CK levels after 15-min swimming exercise. The resting serum levels of AST, ALT, CREA and UA were all significantly decreased with PET+SP. Conclusion: The PET program could increase the exercise performance and modulate the body composition of mice. PET with SP conferred better anti-fatigue activity, improved biochemical profiles, and may be an effective ergogenic aid in strength training. For the product positioning of SP, we suggest that this product could be a potential ergogenic aid and accepted by young athletes by the cost and value compared to the commercial product-whey protein.

Keywords: sake protein; power exercise training; exercise performance; anti-fatigue; Product Positioning

目錄

中文摘要 I
英文摘要 II
致謝詞 IV
目錄 V
圖目錄 VII
表目錄 VIII

第壹章 緒論 1
第一節 研究背景 1
第二節 研究目的 3
第貳章 文獻探討 4
第一節 酒粕介紹 4
第二節 BCAAs 對運動之功效 7
第三節 文獻小節 9
第四節 產品市場定位 10
第五節 文獻小節 15
第參章 材料與方法 16
第一節 實驗測試樣品 16
第二節 實驗動物分組、飼養及實驗流程 18
第三節 血液與組織樣本之收集及前處理 25
第四節 統計分析 26
第肆章 結果與討論 27
第一節 體重、骨骼肌及代謝器官重量 27
第二節 前肢抓力表現 31
第三節 運動耐力表現 32
第四節 15分鐘運動挑戰後血液生化變化之情形 33
第五節 組織中肝醣含量 36
第六節 臨床血液生化質的變化情形 38
第七節 組織病理切片觀察結果 40
第八節 產品市場定位 42
第伍章 結論 44
參考文獻 45
附件一、國立體育大學動物實驗審查同意書 57
附件二、營養成分檢驗標示 58
 

圖目錄
圖 2- 1、產品定位之規劃流程 15
圖 3- 1、PET模式 19
圖 3- 2、PET模式 20
圖 3- 3、實驗流程 21
圖 3- 4、小鼠前肢抓力測量方法 22
圖 3- 5、小鼠運動力竭時間測量方法 23
圖 4- 1、4 週的 SP 補充和 PET 計畫對於體重變化之影響 28
圖 4- 2、4 週的 SP 補充和 PET 計畫於 (a) EFP面積、(b) EFP型態所呈現 30
圖 4- 3、4 週的 SP 補充和 PET 計畫對於前肢握力之影響 31
圖 4- 4、4 週的 SP 補充和 PET 計畫對於小鼠運動耐力表現之影響 32
圖 4- 5、4 週的 SP 補充和 PET 計畫對於小鼠運動挑戰後血液生化影響 35
圖 4- 6、4 週的 SP 補充和 PET 計畫對於小鼠肝醣含量之影響 37
圖 4- 7、4 週的 SP 補充和 PET 計畫對於小鼠組織之影響 40
圖 4- 8、4 週的 SP 補充和 PET 計畫對於小鼠組織之影響 41
圖 4- 9、產品定位 42


表目錄
表 2- 1、植物與動物性蛋白質所含胺基酸成分比較一覽表 13
表 2- 2、競爭者產品市場調查表 14
表 4- 1、各組實驗期間體重與食物攝取以及實驗末各組織臟器重量之紀錄 29
表 4- 2、4週的SP補充和PET計畫對於一般臨床血液生化數值之影響 39
 

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