臺灣博碩士論文加值系統

本研究結合葡萄糖氧化酵素試片、全像光柵及旋光外差干涉術進行葡萄糖濃度之檢測，根據實驗裝置設計與配置完成自準直之光學架構易於量測操作。由實驗結果顯示，在低葡萄糖濃度時，當入射角為49.11°，偏振片方位角設置在20°時，可得到最佳解析度0.6688 mg/dl。本研究所製作之葡萄糖感測試片其反應時間優於2.5秒，並可重複使用50次。

In this study, we integrated an enzymatic glucose sensor and a pair of holographic grating into a circular heterodyne for measuring the glucose concentration. According to the optical configuration, the auto-collimation system can be achieved. The measurement results showed that the best sensitivity of the proposed system was approximated of 0.6688 mg/dl as the optimum measurement conditions were selected.
The response time of the proposed system can be shorter than 2.5 sec and the usage count of the proposed sensor can be more than 50 times.

目錄
書名頁 …………………………………………………………………………… ii
中文摘要 ………………………………………………………………………… iii
英文摘要 …………………………………………………………………………… iv
誌謝 ………………………………………………………………………………… v
目錄 ………………………………………………………………………………… vi
表目錄 ……………………………………………………………………………… viii
圖目錄 ……………………………………………………………………………… ix
第一章 緒論 ……………………………………………………………………… 1
1.1前言…………………………………………………………………… 1
1.2文獻探討……………………………………………………………… 1
1.3研究動機……………………………………………………………… 3
第二章 基本原理 ………………………………………………………………… 5
2.1旋光外差干涉術……………………………………………………… 5
2.2自準直葡萄糖濃度量測技術………………………………………… 9
2.2.1 Dove Prism葡萄糖濃度量測技術………………………… 9
2.2.2自準直架構之架設 ………………………………………… 11
2.2.3自準直架構之最佳化參數…………………………………… 15
第三章 實驗與結果……………………………………………………………… 19
3.1 葡萄糖感測器使用次數之活性測試……………………………… 19
3.1.1 葡萄糖氧化酵素塗層製作方式…………………………… 19
3.1.2 感測器活性檢測方式…………………………………………22
3.1.3 感測器使用次數之呈色結果…………………………………24
3.1.4葡萄糖感測器之保存期限活性測試………………………… 26
3.2 偏振片方位角與相位變化量測結果 ………………………………28
3.2.1 偏振片方位角變化與高濃度之量測結果……………………28
3.2.2 偏振片方位角變化與低濃度之量測結果……………………37
第四章 實驗結果分析與討論…………………………………………………… 42
4.1 感測器量測結果之分析……………………………………………42
4.2 系統誤差分析………………………………………………………45
4.2.1 偏振旋轉誤差……………………………………………… 45
4.2.2 偏振混合誤差……………………………………………… 48
4.2.3 入射角 誤差…………………………………………………51
4.2.4 偏振片方位角α誤差……………………………………… 53
4.2.5 系統穩定度測試…………………………………………… 55
4.2.6 系統誤差與解析度評估…………………………………… 58
4.3 小結 ……………………………………………………………… 60
第五章 結論與未來展望 ……………………………………………………… 61
參考文獻…………………………………………………………………………… viii

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