臺灣博碩士論文加值系統

台灣，位於熱帶與亞熱帶氣候區的交界。近年來由於溫室效應的影響使得平均氣候溫度越來高，尤其在夏天中，台灣人們更感覺到酷熱難耐。本研究利用氣相層析儀來偵測自製清涼劑液態皂中薄荷醇和冰片成分
本研究建立的氣相層析分法:管柱為HP-50+ (30m×0.25mm×0.25mm)，注入口溫度為230 ℃，注射量為1μL，偵測器為火焰離子偵測器，偵測器溫度為250 ℃。
在確效實驗裡，薄荷醇的相對標準偏差為1.46%~3.59%，回收率為98.87%，線性迴歸R2=0.999，偵測極限4.48 ppm，定量極限14.9ppm。而冰片的相對標準偏差為0.81%~2.31%，回收率為98.69%，線性迴歸R2=0.9999，偵測極限3.30ppm，定量極限11.0ppm。
在安定性試驗中，用自製的清涼劑液態皂分別在25℃和40℃的條件下放置六個月後，發現兩種條件溫度下皆無明顯外觀的改變。清涼劑液態皂放置在25 OC六個月後薄荷醇含量為96.4%，冰片含量為96.1%。清涼劑液態皂放置在40OC六個月後薄荷含量為95.1%，冰片含量為94.6%，由此可見清涼劑液態皂安定性很好。

Taiwan's climate zones is located between the tropics and subtropics. For the past few years, due to the average climate increasingly high temperatures lead by greenhouse effect. Especially at summer, Taiwan people more felt unbearably hot. The GC method to analyze these two of Borneol and Menthol in the refreshing liquid soap.

The developed GC method was performed with the conditions: =HP-50+ column(30 m×0.25mm×0.25mm), injection temperature is 230 ℃,injection amount is 1µL, FID detection temperature 250 ℃.

In the results of validation experiment ,the relative standard deviation (RSD) of Menthol is ranged form 1.46%~3.59%, the average recovery was 98.87%, the linear regression coefficient R2=0.999, and the limits of detection (LOD) and quantification (LOQ) were 4.48 ppm and 14.9ppm,respectively. The relative standard deviation (RSD) of Borneol is ranged form 0.81%~2.31%, the average recovery was 98.69%, the linear regression coefficient R2=0.9999, and the limits of detection (LOD) and quantification (LOQ) were 3.30ppm and 11.0ppm,respectively.

In the stability tests, refreshing liquid soap was placed in the room temperature condition 25℃ and the accelerated condition 40℃ for six-month stability test.The appearance of product did not significantly change. The product is put at 25℃condition for six-month, Menthol content remained at 96.4%, Borneol content remained at 96.1%. The product is put at 40℃condition for six-month, Menthol content remained at95.1%, Borneol content remained at94.6%.

中文摘要……………………………………………………………... Ι
英文摘要……………………………………………………………... ΙΙ
誌謝…………………………………………………………………... ΙΙΙ
目錄…………………………………………………………………... IV
表目錄………………………………………………………………... VI
圖目錄………………………………………………………………... VΙΙ
第一章 緒論…………………………………………………………. 1
1-1 前言……………………………………………………………… 1
1-2 研究目的………………………………………………………… 2
1-3 主要成份介紹…….…………………………………………….. 3
1-4 氣相層析儀器介紹…….……………………………………….. 6
第二章 實驗方法……………………………………………………. 13
2-1 藥品……………………………………………………………… 13
2-2 儀器設備………………………………………………………… 14
2-3 分析條件………………………………………………………… 15
2-4 標準貯存溶液…………………………………………………… 16
2-5 清涼劑液態皂的製備…………………………………………… 16
2-6 不同溫度及時間對於清涼劑液態皂之安定性試驗…………… 18
2-7 GC分析方法之確效……………………………………………... 18
第三章 結果與討論…………………………………………………. 21
3-1 不同溫度及時間對於清涼劑液態皂之安定性研究…………… 21
3-2 不同溫度及時間對於清涼劑液態皂外觀試驗………………… 23
3-3 分析方法之確效……..………………………………………….. 24
第四章 結論…………………………………………………………. 37
第五章 參考文獻……………………………………………………. 38

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