臺灣博碩士論文加值系統

本研究主要係藉由光學顯微鏡、掃描式電子顯微鏡、X光繞射儀、穿透式電
子顯微鏡、硬度測試、接觸角測試及生物檢測等設備進行分析Ti-25Ta之β型生醫
鈦合金高溫顯微結構、機械特性與生物相容性之關係性。研究結果發現；針狀?恁?
麻田散鐵相之體積分率會隨熱處理溫度上升而減少，當合金被熱處理於700°C至
1000°C持溫30分鐘後，其結構本質為一(?? + ?恁?)相結構。TTa-3試片呈現最大之為
硬度約為Hv743。而TTa-3與TTa-4試片則具較親水性表面，其接觸角各別為
73°與69°。此外，MTT檢測結果亦顯示；經熱處理過後之合金試片並不會釋出具
有毒性之金屬離子至細胞中，而這些結果與特徵有助於進一步了解此合金之顯微
結構、機械性質與生物相容性之間關係，可發展成一具潛力之醫用合金以供牙科
醫療器材產業應用。

The Ti-25Ta alloy was characterized via optical microscopy, scanning electron
microscopy, X-ray diffraction, transmission electron microscopy, hardness test,
contact angle test and biological assay. It was found that the volume fraction of the
needle-like ?恁? martensite phase decreased with increasing the heat treatment
temperature. When the alloy underwent heat treatment at temperatures between 700°C
and 1000°C, its microstructure was essentially a (?? + ?恁?) phase structure. The
hardness test results for the TTa-3 sample exhibits the maximum Hv value to those
samples around Hv743. For the TTa-3 and TTa-4 samples, they exhibit a relatively
hydrophilicity surfaces. The average contact angles of the TTa-3 and TTa-4 samples
are 73° and 69°, respectively. Moreover, the MTT assay results also indicated that the
heat treated samples were not released toxic metallic ions to cells. These results and
features can be useful in further understanding the relationship between the
microstructure, mechanical behavior and biocompatibility of the alloy, to
development as a potential biomedical alloy.

中文摘要...............................................Ⅰ
Abstract............................................. Ⅱ
總目錄.................................................Ⅲ
Figure captions.......................................IV
Table captions........................... ............VII
CHAPTER 1 INTRODUCTION…………………………………………………..1
1.1 Research motivation.………………………………………..…………………...1
1.2 Literature review………….……………………………………………………5
1.2.1 Properties of Ti and Ti-based alloys…………..…………………………………5
1.2.2 Classifications of Ti-based alloys…………………….………..………………..7
1.2.3 Phase transformations of Ti-based alloys……………………………………….8
CHAPTER 2 MATERIAL AND METHORDS……………………………………..10
2.1 Casting of the investigated alloy………………………………..……………..10
2.2 Heat treatment procedures…………………………………………………….….10
2.3 Optical microscopy (OM)……………………………………….……………….10
2.4 Scanning electron microscopy (SEM)………………..…………...……………...11
2.5 X-Ray diffraction (XRD)……….………………………………………………..13
2.6 Transmission electron microscopy (TEM)……………………………………….13
2.7 Nano-indentation……………………………………………………………….15
2.8 Wettability………………………………………………………………………16
2.9 Cell response and proliferation assay…………………………………………….16
CHAPTER 3 RESULTS AND DISSCUSSION…………………………………18
CHAOTER 4 CONCLUSION……………………………………………………..22
REFERENCES………………………………………………………………..25

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