臺灣博碩士論文加值系統

使用台積電 90 nm CMOS製程的非侵入式血糖量測系統。系統由操作在28至30 GHz的發射機、接收機和平板天線組成。藉由毫米波訊號通過不同的血糖濃度的耳垂組織會造成不同的衰減來判斷血糖值高低。仿生組織的成分使用介電係數測量儀器確認其與人體相似度。毫米波訊號 (28~30 GHz) 由發射機生成，訊號經過厚度為5.5毫米且葡萄糖濃度為100和200 mg/dl的仿生耳垂組織後被接收機接收，由接收機分別將不同濃度的訊號轉換為10位數的數位輸出 0011111001 和 0101111000。量測系統包含發射機與接收機的總功耗為156 mW。 PCB的尺寸為36.1×28.3 mm2。考慮到電池轉換效率後(85%)，容量為45 mAh的聚合物鋰電池(16×10×4mm3)可使系統運行860秒，如果每天測量8次，每次測量需要1秒，則該系統可以使用約108天。根據2013年版的ISO 15197，血糖在100至200 mg / dl之間的允許誤差為15 mg / dl。該系統可檢測的最低血糖值為0.64 mg / dl，符合ISO 15197的標準。

A non-invasive glucose measurement system is fabricated using TSMC 90-nm CMOS technology. The measurement system consists of a transmitter, a receiver and patch antennas that works from 28 to 30 GHz. The blood glucose level is determined by the measurement attenuation caused by earlobe tissues of different glucose concentrations. The permittivity of mimicking phantoms is verified by the dielectric probe kit to confirm its similarity to human body. The millimeter wave (MMW) signal is generated by the transmitter. After being passed through the 5-mm earlobe mimicking phantoms with glucose concentrations of 100 and 200mg/dl, the signal is converted by the receiver to the 10-bit digital out-put 0011111001 and 0101111000, respectively. The total power consumption of the measurement system is 156 mW. The size of PCB is 36.1 × 28.3 mm2. The measurement gain of receiver is 26.6 dB at 27.5 GHz. A polymer lithium battery (16×10×4mm3) with a capacity of 45 mAh can let the system operate for 860 seconds after considering the battery conversion efficiency (85%), so that this system can be used for 108 days, if we measure 8 times a day and each measurement takes 1 second. According to the 2013 edition of ISO 15197, the allowable error of the blood glucose range between 100 to 200 mg/dl is 15 mg/dl. The minimum detectable blood glucose level by this system is 0.64 mg / dl, which meets the standard of ISO 15197.

摘要 III
Abstract IV
誌謝 V
Table of Contents VI
List of Figures VII
List of Tables X
Chapter 1 : Introduction 1
1.1 Background and Motivation 1
1.2 Organization of Thesis 2
Chapter 2 : Mimicking Phantom 3
Chapter 3 : System Architecture 8
3.1 System Illustration Diagram 8
3.2 System Requirement and Receiver Block Diagram 9
3.3 Receiver Circuit Design 11
3.3.1 Programmable-gain LPF 11
3.3.2 Peak Detector 13
3.3.3 10-bit Successive approximate register analog-to-digital converter (SAR-ADC) 14
3.4 Simulation Results of Receiver 21
3.4.1 Programmable-gain LPF 21
3.4.2 Peak detector 25
3.4.3 10-bit SAR ADC 27
Chapter 4 : Measurement Result 31
4.1 Chip Layout and Microphotograph 31
4.2 Receiver Building Block Measurement Results 34
4.2.1 Programmable-gain LPF 34
4.2.2 Peak Detector 36
4.3 Receiver Measurement Results with NA 38
4.3.1 Measurement Results without phantom 38
4.3.2 Measurement Results with phantom 41
Chapter 5 : Conclusion & Future Work 43
Reference 46

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