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The aim of this study was to evaluate the association between postmenopausal osteoporosis and kidney-vacuity syndrome. Eighty- one postmenopausal females were enrolled and their age were within 40 to 65 years. Bone density examination was performed by DEXA technique and received questionnaire. The diagnosis of osteoporosis was made by 2.5 standard deviation below the bone density of the youth. Kidney-vacuity syndrome was deduced according to the diagnostic criteria developed in National Congress on Chinese Medicine and Sino-Western Combined Geriatric Medicine held in Mainland China in 1986. The mean age of non- osteoporosis group was 54.0±4.8 years old and the osteoporosis group was 58.9±5.9 years old. The results showed that the patients with kidney-qi-vacuity and kidney-yin-vacuity were more likely to have osteoporosis than those who were not. There was no significant difference between kidney-yang-vacuity group and non-kidney-yang-vacuity group in their rates of osteoporosis. Also the group with kidney-qi-yin-vacuity had higher probability to get osteoporosis than those kidney-qi-vacuity or kidney-yin- vacuity. By logistic regression analysis the patients with kidney-qi-vacuity or kidney-yin-vacuity were more likely to get osteoporosis than those with non-kidney-qi-vacuity or non- kidney-yin-vacuity. In conclusion, there were marked association between kidney-vacuity syndrome and postmenopausal osteoporosis. Patients with kidney-qi-yin-vacuity syndrome were more likely to get osteoporosis than those with kidney-qi- vacuity syndrome or kidney-yin-vacuity syndrome.
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