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The main purpose of this study is to develop an algorithm to solve the interaction and nonlinear problems in chemical processes. The other purpose is to develop a method for determination of the optimal operation in a complicate process. The temperature control exhibits poor performance in a high purity distillation column. The on-line analysis control poses difficulties due to the presence of the long dead-time. A dynamic state variable estimator (DSVE) is proposed in this study. We demonstrate the potential and versatility of NNM for developing DSVE particularly useful for inferential product composition estimation and control in a high purity distillation column. A nonlinear simplified decoupler is developed based on a neural network model(NNM). The NNM decoupler is applied to a simulated CSTR and distillation column, respectively. The results of the simulation study show the good capability of the NNM decoupler for multivariable systems.The crude fractionation column is a complicate process. It contains 13 manipulated variables and 7∼8 controlled variables. In this study, a crude fractionation column model is developed based on a neural network. The predicted results of neural network model match the plant operating data well. A combination of the neural network model and a successive quadratic programming (SQP) algorithm is employed to determine the optimal operating conditions of the crude fractionation column.Many control strategies applied to a high purity distillation column with a sidestream are illustrated in this study. We compare the differential temperature control and double differential temperature control, the direct internal reflux control and indirect internal reflux control.The simulation results show the excellent capability of the feed-forward control to disturbance rejection. An indirect model-base control strategy applied to product composition control of a high purity distillation column is also developed. The indirect internal reflux control, feed-forward control, and indirect model-base control strategies are successfully implemented to a commercial distillation column.
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