臺灣博碩士論文加值系統

本研究主要是研發溫度感覺神經系統研究中所需要的冷熱溫度刺激器 .
傳統的電生理研究常以電刺激器做為誘發神經信號的工具 ,但是不同的感
覺形式是經由不同的神經纖維所傳導 ,使用電刺激器很難產生單純特定形
式之感覺刺激 ,並且也會造成不同的感覺神經同時激發 ,所以電刺激器僅
能提供類似解剖和染色的訊息 ,因此如何誘發單一形式的感覺神經信號是
研究感覺生理最重要的課題之一 . 本刺激器可設定的溫度範圍在-10度C
到70度C之間 ,在溫度最高下降速率及溫度最高上升速率分別為每秒4.11
度C及8.31度C ,並在貼附人體手臂表面之試驗可提供穩定的溫度輸出 ,其
誤差在正負0.1度C內 . 另一方面 ,因糖尿病患者對於溫度與疼痛的感覺
有惡化的情形 ,所以我們希望本刺激器應用在臨床上的非侵入性的皮膚溫
度分辨測試 ,以作為第一型糖尿病早期診斷之先期研究上 .

The main goal of this study is to develop a temperature
stimulator forthe research of the sensory nervous system."
Peltier device",thermoelectriccooling module,is the main device
generates the source of temperature stimulusin this stimulator.
An adequate "stimulator" is very important for the study of the
sensorynervouss system. An electric stimulator is usually used
for such purpose. However, it is impossible to elicit a specific
sensory sensation by utilizing electric stimulation. The
information obtained by electric stimulation is thusmore
anatomical basis than functional ones. A precise temperature
stimulation is needed in our laboratory. Hence,we develop it.
The temperature range of this stimulator is from -10 degree C to
70 degree C.The maximum temperature falling and rising rates are
4.11 degree C/Sec and 8.31 degree C/Sec. The error of the
temperature setting of this device is -0.1 to 0.1 degree in
human skin test. Type I diabetic patients have the
deterioration of temperature and painsense. The "temperature
stimulator" provides a mean for the noninvasive cutaneous
temperature discrimination in clinical diagnosis.