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研究生:徐瑞蓮
研究生(外文):HSU, Jui-Lien
論文名稱:主動脈雙葉片人工心瓣之回流流場量測
論文名稱(外文):The Measurement of the Retrograde Flow Field of Bileaflet Artificial Heart Valves
指導教授:盧博堅盧博堅引用關係
指導教授(外文):LU Po-Chien
學位類別:碩士
校院名稱:淡江大學
系所名稱:水資源及環境工程學系
學門:工程學門
學類:環境工程學類
論文種類:學術論文
論文出版年:1998
畢業學年度:86
語文別:中文
論文頁數:85
中文關鍵詞:雙葉片人工心瓣回流雷諾應力雷射測速儀
外文關鍵詞:bileaflet artificial heart valveretrograde flowReynolds stresslaser Doppler Anemometer
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本研究針對四種已被採用的雙葉片機械人工瓣膜St. Jude Medical (SJM)
、CarboMedics (CM)、Edwards Tekna modified DuroMedics (DM)、
Sorin Bicarbon (SB)進行主動脈瓣回流流場體外量測,以雷射都卜勒測
速儀(Laser Doppler Anemometer , LDA)於心瓣間隙上游作近場速度量測
,依據試驗結果,計算平均回流速度及雷諾應力,與血球破壞力的文獻比
較,並且比較四種機械人工雙葉片心瓣設計上的差異對流場之影響。實驗
設置為一個能夠產生符合人類血壓及流量波形的左心室血管模擬循環系統
,系統控制在符合生理脈動波形範圍,維持每分鐘心臟輸出量為5升及每
分鐘心跳為70下。量測位置著重於當心瓣關閉時可能產生回流的位置,即
在雙葉片心瓣的葉片與葉片之間,葉片與心瓣環座之間以及支撐轉軸的間
隙。SJM、CM、DM及SB其心瓣關閉時回流流場之最大平均速度皆於關閉初
期發生在葉片間隙之回流射流中央點,且最大平均速度與最大雷諾應力同
時發生。SB最大軸向回流平均速度U= -0.5 m/sec,其次DM為-0.47 m/sec
,SJM為-0.45 m/sec,CM為-0.25 m/sec,SB具有最大主軸雷諾正向力與
雷諾剪應力為1950 dynes /cm2與800 dynes/cm2,其次依序是DM、SJM及
CM。此四種心瓣擾動應力與文獻比較,實驗結果發現四種心瓣之最大主軸
剪應力值300至800 dynes/cm2之間,皆已達到破壞血小板之臨界值。
A series of tests were performed on the currently used St. Jude
Medical (SJM), CarboMedics (CM), Edwards Tekna modified
DuroMedics (DM) and Sorin Bicarbon (SB) bileaflet artificial
heart valves. Flow velocity was measured with a laser Doppler
Anemometer in order to compare the four valves by their
influence towards various retrograde flow fields and as revealed
in relative documents, their relation with blood element damage.
All experiments were performed with a pulse duplicator
simulating the left side of the human circularity system under
the following condition: a cardiac out put of 5 L/min, a
constant heart rate of 70 beats/min, and pressure wave forms
within the physiological range. The measurement points were
primarily located at the gaps between the closed leaflets during
diastole, between the leaflets and housing ring, and the hinges.
Results show that the peak values of reverse velocity of all
four valves during diastole are concentrated at the center of
the gap between the leaflets Meanwhile, the peak reverse
velocity and peak Reynolds shear stress own simultaneously. The
average peak reverse velocities of SB, Dm, SJM, and CM are U =
-0.50 m/sec, -0.47 m/sec, -0.45 m/sec, and -0.25 m/sec,
respectively. SB has the highest peak Reynolds normal and shear
stress values, which are 1950 dynes/cm2 and 800 dynes/cm2,
followed by DM, SJM, and CM. The peak Reynolds shear stress
values of all four valves range from 300 to 800 dynes/cm2, which
exceeds the threshold of platelet damage.
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