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研究生:孫海倫
研究生(外文):Helen-Sun
論文名稱:中部地區氣喘病童家中塵璊調查
論文名稱(外文):Prevalence and Distribution of House Dust Mite in Taichung
指導教授:呂克桓呂克桓引用關係
學位類別:碩士
校院名稱:中山醫學院
系所名稱:醫學研究所
學門:醫藥衛生學門
學類:醫學學類
論文種類:學術論文
論文出版年:1999
畢業學年度:87
語文別:中文
論文頁數:49
中文關鍵詞:塵璊氣喘
外文關鍵詞:MiteAsthma
相關次數:
  • 被引用被引用:1
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摘要
隨著盛行率的提高,因氣喘而致死的病例也時有所聞,如何治療及做好環境控制來防治氣喘,是醫界一直以來的努力方向,塵璊是所有過敏原中最多也最常見的一種;在世界各地都陸續有塵璊的調查研究,在台灣的調查僅限於台北地區,其他地區的資料則是十分有限。
本研究依前人的模式,在中部氣喘病童家中在四個不同部位:客廳地板,客廳沙發,臥室地板,臥室床舖,為期一年每隔兩個月採樣一次,同時與對照組做比較,並對所採得璊類做進一步的種類鑑定,共有8名實驗組及4名對照組。
研究結果顯示:以實驗組及對照組一年的塵璊分佈來說,並沒有明顯的差異。隨著溫度的降低,塵璊量在冬季(1月份)時最少,之後,隨著溫度升高而增加,以分佈部位而言,在臥室床墊的含量最高,且與對照組相較有統計學上的意義。可是在與氣喘發作的頻率而言,和塵璊量並沒有正相關的發現。至於璊類的族群仍是以歐洲室塵璊佔最大部份(77%),美洲室塵璊次之(13%),至於熱帶無爪璊則只佔1%。
氣喘是一個多因子誘發的疾病,除了在藥物治療外,環境控制更是治療的第一步。由本研究可知,在中部地區,病童長時間密切接觸的床墊,更是防治的重點。
Abstract
Many studies including skin test and radioallergosorbent test (RAST) strongly suggested that house dust mite are the most important allergen in Taiwan, especially in asthmatic children. Taiwan is a subtropical island. The high temperature and relative humidity throughout the year and overcrowding are ideal condition for mite growth. There were few reports about distribution of mite in Taiwan especially in Taichung.
We collected every two months between June 1998 and May 1999 from eight houses of mite-allergic patients and four normals. About 1m surface area, each of living room, floor, sofa, bed room and mattress was vacuumed for one minute. The floating method was used to collect mites in dusts and the mites were countered under stereo-microscope. House dust mites species were identified, too.
The results showed the following five points. First, the average number of mites in patients’ houses was not different that in normal’s houses. Second, the total mite amounts were greater in July to November and lowest in January. It was compatible with the lowest temperature in January with constant relative humidity all the year. Third, the mattress was the largest mite amount among four different vacuumed areas. Forth, the total amount of mites was not correlated with the frequency of asthma attacks. Fifth, the Dermatophagoides pteronyssinus (DP) was the dominant specie (77%) of house dust mites found in Taichung and Dermatophagoides farinae (DF) was the second (13%).
Environmental control of house dust mites is the first line management for mite-sensitive asthmatic patients. Mattress is a very important area to reduce the mite amounts according to our study.
目 錄
中文摘要
英文摘要
第一章 研究問題的發展
第一節 研究背景…………………………….1
第二節 研究動機…………………………….3
第三節 研究目的…………………………….5
第四節 研究假設…………………………….6
第二章 文獻回顧
第一節 塵璊的分佈………………………….7
第二節 璊類的分離與鑑定………………….13
第三章 研究方法
第一節 研究設計…………………………….16
第二節 研究工具…………………………….17
第三節 研究實施步驟……………………….18
第四章 研究結果
第一節 研究對象基本資料…………………..21
第二節 一年中塵璊分佈情形………………..23
第三節 塵璊分佈與溫度及相對濕度的關係..32
第四節 不同採樣部位的塵璊分佈…………..33
第五節 一年中氣喘發作次數………………..34
第六節 塵璊的鑑定 ………………………….35
第五章 討論
第一節 一年中塵璊的分佈情形……………..36.
第二節 塵璊分佈與溫度及相對濕度的關係..38
第三節 不同採樣部位的塵璊分佈…………..39
第四節 塵璊分佈與氣喘發作………………..41
第五節 塵璊的種類…………………………..42
第六節 結論…………………………………..43
第七節 研究限制及建議……………………..44
參考文獻…………………………………………45
附圖………………………………………………48
參考文獻
1. A. Fain, B Guerin, B. J. Hart. Mites and Allergic Disease. F-55270 Varennes En Argonne , France. 1990.
2. Arlian LG, Bernstein D, Bernestein ZL, et al. Prevalence of dust mites in the houses of people with asthma living in eight different geographic area of United States. J. Allerg Clin Immunol 1992;90:292-300
3. Carswell F. The relationship between mite allergy exposure and asthma severity. Clin Exp allergy 1995;25;99-101.
4. Chih-Shan Li, Gwo-Hwa Wan, et al. Seasonal variation of house dust mite allergen (Der p 1) in a subtropical climate. J. Allergy Clin. Immunol. 1994;94:131-134
5. Domrow R: Seasonal variation in numbers of the house dust mite in Brisbane. Med J Aust 1970;2:1248.
6. Guy B Marks, Eurar R. Tovey et al. Mite allergen (Der p 1) concentration in houses and its relation to the presence and severity of asthma in a population of Sydney schoolchildren. J. Allerg Clin. Immunol 1995;96:41-448
7. Hayden ML, Rose G, Kent B, et al. Benzyl benzoate moist power: investigation of acarical activity in cultures and reduction of dust mite allergens in carpets. J Allergy Clin Immunol 1992;89:536-45.
8. Hughes MA, Maunsell K: A study of population of house dust mites in its nature environment. Clin Allergy 1973;3:127.
9. Kenneth S Babe, Larry G, Arlian et al. House dust mites (Dermatophagoides farinae and Dermatophagoides pteronyssinus) prevalence in the roons and hallways of a tertiary care hospital. J. Allerg Clin Immunol 1995;95:801-805
10. Korsgaard J, Iversen M. Epidermiology of house dust mite allergy. Allergy 1991;46 (suppl) 11:15-8.
11. Leonardo Puerta MS et al. Sequential determinations of Blomia tropicalis allergens in mattress and floor dust samples in a tropical city. J Allergy Clin Immunol 1996;97:689-91.
12. Lintner TJ, Brame KA. The effects of season, climate, and air-condition on the prevalence of Dermatophagoides mite allergens in household dust. J Allergy Clin Immunol 1993;91:862-7.
13. L. Zhang, F. T. Chew et al. Prevalence and distribution of indoor allergens in Singapore. Clinical and Exp. Allergy 1997;27:876-885
14. M. Chan-Yeung, A backer, et al. House dust mite allergen levels in two cities in Canada: effects of season, humidity, city and home characteristics. Clinical and Experiential Allergy, 1995;25:240-246
15. Moyer DB, Nelson HS, Arlian LG: House dust mites in Colorado. Ann Allergy 1985;55:680-2.
16. Murray AB, Ferguson AC ,Morrison B: The seasonal variation of allergic respiratory symptoms induces by house dust mites. Ann Allergy 1980;45:347-350
17. Murry AB, Zuk P: The seasonal variation in a population of house dust mite in a North American City. J Allergy Clin Immunol 1979;64:266-9.
18. Platts-Mills TAE, de Weck AL. Dust mite allergens and asthma- a world wide problem. J Allergy Clin Immunol 1989;83:416-27.
19. Platts-Mills TAE, Hayden ML, Chapman MD, et al: seasonal variation in dust mite and grass-pollen allergens in dust from house of a patient with asthma. J Allergy Clin Immunol 1987;79:781-91.
20. Pong-Ho Nahm, Hae-Sim Pank, et al. Seasonal variation of skin reactivity and specific IgE antibody to house dust mite. Annals of Allergy, Asthma & Immunology 1997;78:589-593
21. Sakaguchi M, Inouye S et al. Seasonal changes in mite allergen concentrations in Japanese homes. Ann Allergy Asthma Immunol 1996;76:170-4.
22. Sorrik R, chapman MD, Platta-Mills TAE. House dust mite exposure as a cause of asthma. Clin Exp Allergy 1992;22:897-906.
23. S. Van der Heide et al. Seasonal difference in airway hyperresposiveness in asthmatic patients : relationship with allergen exposure and sensitization to house dust mites. Clinical and Exp Allergy .1997;27:627-633.
24. Tovey Er, Chapman MD, Platts Mills TAE :Mite feces are a major source of house of house dust allergens. Nature 1981;289:582-3.
25. Von Brownijk JEMH: Dermatophagoidoes pteronyssinus (Troussart 1897) in mattress and floor dust in a temperate climate. J Zool Entomol 1973;10:63.
26. Voohorse,R,F. Th. M. Spieksma, H. Verekamp. 1967. The house - dust mite and the allergens it produces. Identity with the house-dust allergen. J. Allergy 39(6):325-339.
27. Woolcock AJ. Peat JK, Trevillion LM. Is the increase in asthma prevalence linked to increase in allergen load? Allergy 1995;50:935-40.
28. Yi-Chung Chang and Kue-Hsiung Hsieh. The study of house dust mites in Taiwan. Annals of Allergy. 1989;62:101-106.
29. 吳懷慧博士論文: 臺灣塵璊生物學與致敏性之研究. 1996
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