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研究生:陳德升
研究生(外文):De-Sheng Cheng
論文名稱:農藥水懸劑技術之研究與開發
論文名稱(外文):The Research and Development of the Technology for Suspension Concentrate of Pesticides
指導教授:陳家鐘陳家鐘引用關係
指導教授(外文):Chia-Chung Chen
學位類別:碩士
校院名稱:朝陽科技大學
系所名稱:應用化學系碩士班
學門:自然科學學門
學類:化學學類
論文種類:學術論文
論文出版年:2001
畢業學年度:89
語文別:中文
論文頁數:72
中文關鍵詞:水懸劑球磨機研磨配方理化安定性
外文關鍵詞:Suspension concentrateBall millmillingformulationphysical and chemical stabilities
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中文摘要
水懸劑(Suspension concentrate)使用時比起粉劑或可濕性粉劑較為方便安全,本實驗將國內之可濕性粉劑生產量較高者的四氯異苯、賓克隆、加保利、草殺淨、免賴得、納乃得等六種之農藥原體配製為較安全的水懸劑劑型。
在水懸劑製劑流程中,研磨為非常重要的步驟,本實驗使用振盪搖瓶機研磨,以適合實驗室小量製劑配方的研究及使用球磨機(Ball mill)、溼式研磨機(Dyno mill)研磨,以模擬工廠量產製程。另外配方調製上,調整各主成份含量,依其性質不同,分別為18﹪~40﹪之間。依據成品的自動分散性,選擇適當界面活性劑及觀察成品的黏度、流動性及懸浮性等物理狀態,調整增黏劑或其他添加物的含量,選擇出最佳的配方。
最後這些水懸劑成品的顆粒粒徑分佈、黏稠度、自動分散性、懸浮率、流動度及儲存安定性等檢測結果,除免賴得外,其餘各項理化安定性數值均合乎國內標準。免賴得雖然在本實驗中得到好的配方,但該原體在水中極易水解,故免賴得不適合應用水懸劑。

Abstract
The suspension concentrate is more convenient and safer to use than dustable powder and wettable powder as formulation forms. In this study, six active ingredients of pesticide such as chlorothalonil, pencycuron, benomyl, methomyl, carbaryl and ametryne were used in the formulation research. Currently these six pesticides are used in large quantity as wettable powder in Taiwan and should be converted into safer formulation-suspension concentrate.
In the preparation process for suspension concentrate, milling is a very important step. In this study, laboratory shake-machine was used for grinding for small-quantity formulation in laboratory. For different scales, ball mill and Dyno mill were used for grinding to simulate large-quantity formulation process in plants.
In the formulation study, the concentrations of active ingredients are adjusted in the range of 18%~40% and the selection of surfactants were carried out according to their physical properties. After the proper formulations were defined, the suspension concentrates were tested on their particle size distribution, spontaneity in water, suspensibility in water, viscosity and storage stability. Modifications in formulation additives were carried out based on the above test results to obtain the best formulations.
Except benomyl, all the suspension concentrates have good physical and chemical stabilities according to the regulations approved by the Council of Agriculture in Taiwan. This formulation technology is ready for transferring to the domestic agrochemical manufacturers. Benomyl active ingredient decomposes completely after storage test due to its rapid hydrolysis rate. Therefore, suspension concentrate is not a good formulation for benomyl.

第一章 簡介
第一節 實驗緣由及目的…………………………………………1
第二節 前人研究…………………………………………………4
第三節 配方內容簡介……………………………………………7
第四節 製程………………………………………………………9
第五節 未來展望…………………………………………………10
第二章 實驗材料與方法
第一節 材料和儀器 ……………………………………………11
第二節 實驗方法 ………………………………………………16
第三章 結果與討論………………………………………………… 29
第四章 結論………………………………………………………… 35
參考文獻……………………………………………………………… 36
表、圖………………………………………………………………… 43

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