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研究生:連政平
研究生(外文):Cheng-Ping Lain
論文名稱:高雄地區勞工口腔黏膜異常影響因子之探討
論文名稱(外文):The Analysis of Influence in Affecting Factors about Oral Mucosal Lesions of the Labors in Kaohusiung District
指導教授:謝天渝謝天渝引用關係楊奕馨楊奕馨引用關係
學位類別:碩士
校院名稱:高雄醫學大學
系所名稱:口腔衛生科學研究所
學門:醫藥衛生學門
學類:牙醫學類
論文種類:學術論文
論文出版年:2001
畢業學年度:89
語文別:中文
論文頁數:52
中文關鍵詞:口腔黏膜下纖維化症口腔白斑症口腔黏膜異常
外文關鍵詞:OSF
相關次數:
  • 被引用被引用:11
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中文摘要
本次研究之目的,乃是分析高雄地區勞工口腔黏膜異常與嚼食檳榔、抽菸、喝酒、職業類別、性別以及年齡組別之相對關係。於1999年5月至6月共檢查成年勞工3928人,平均年齡44.8歲。其中,嚼食檳榔、抽菸、喝酒之盛行率分別為9.55%、28.11%以及15.58%。此外,男性嚼食檳榔者有11.00%、抽菸者有32.10%、以及喝酒者有17.90%。
根據近年來的研究顯示,台灣地區之報告偏重於口腔癌之病歷對照分析及其與檳榔、菸、酒之加成相關性。而其他嗜嚼食檳榔的東南亞國家,其主要以口腔黏膜疾病為流行病學研究其疾病形態,而較少探討檳榔、菸、酒之加成相關問題。
在本研究中可發現,陽性個案比率以31歲至45歲較高,且男性高於女性,技術類勞工高於工管類勞工。同時,檳榔、抽菸習慣數量大之勞工於此次檢查中,其陽性個案百分率高達百分之三十。
從本研究之結果,嚼食檳榔與口腔黏膜異常有其相關性。沒有嚼食檳榔習慣的人,其陽性個案百分比為1.49,而且沒有口腔黏膜下纖維化。而且,嚼食檳榔已被視為口腔黏膜病變最主要之危險因子,與不抽菸、不吃檳榔、不喝酒的人相比,其危險對比值(OR)為29.25。在研究中,經卡方檢定顯示:白斑之部位與抽菸量有關,但與吃檳榔、喝酒之用量則沒有顯著性相關。同時亦由卡方檢定得知,疾病組別與檳榔、抽菸、和酒習慣組合有關。
相較於東南亞國家之大規模口腔黏膜病變篩檢,台灣地區於1999年開始,衛生署亦進行一項三年五十萬人之口腔黏膜病變之篩檢工作。本次研究於此篩檢活動之際,希望在相關法令配合之下,勞工之健康檢查中口腔檢查列入常規項目,在三年之計畫結束之後,應以勞工健康檢查為目標,繼續五年至十年之後續追蹤工作,如此台灣地區之口腔癌及相關疾病之防制工作能更趨完整,相信必有助於降低口腔癌之發生率。
ABSTRACT
The purpose of this study was to analysize labors in Kaohsiung district s the correlation between oral mucosal lesions and betel quid chewing, smoking, alcohol drinking habits, occupation, sex and age group. Through hospital oral mucosa survey in Kaohsiung city, 3928 persons with average age of 44.8 were screened within 2 months.
The prevalence of betel quid chewing, smoking and alcohol drinking were 9.55%, 28.11%, and 15.58%, respectively. For men, on the other hand, the data are 11.00%, 32.10% and 17.90%.
According to the researches in recent years, most of the Taiwanese papers focused on the hospital study about oral cancer patients and discussed the additive effects of betel quid chewers with smoking or alcohol drinking. In other countries with betel quid chewers, researches were mainly studied on oral mucosal diseases, and were seldom discussed on the additive effects of betel quid chewers with smoking or alcohol drinking
In this oral mucosal survey of the labors in Kaohsiung district, the percentage of positive case is higher at the age group of 31-45; besides, the percentage of positive case is also higher in the male and
technological labors. Furthermore, we found that the percentage of positive case is over 30% in the labors who have more amounts in betel quid chewing or cigarette smoking.
From the result of this oral health survey, it showed us that there were correlations between betel quid chewing habit and oral mucosal lesions. Only 1.49% of those, who did not have betel quid chewing habit, had oral mucosal lesions, and none of them had oral submucosa fibrosis. Furthermore, the betel quid chewing habit was considered as the greatest risk factor among all factors. The OR was 29.25 for betel quid chewers to have oral mucosal lesions as compared to those who did not have betel-quid chewing, smoking and alcohol drinking habits.
In this research, based on the Chi-square test we made, there is a significant difference among the locations of leukoplakia due to the amount in cigarette smoking, but there is no significant difference among the locations of leukoplakia due to the amount in betel quid chewing and alcohol drinking.
Comparing to the oral mucosal lesions survey in southeast Asian nations, the National Health Administration in Taiwan held a survey from 1999 to 2001. It is working on examining five hundred thousand people who chew betel quid. The research, cooperating with rules and laws, is expected that oral health surveys could be a routine examination. As the plan ending in 2001, we should continue the tracing work for five to ten years by means of the labor-health-examination. Therefore ,it is believed that the preventions of oral cancer and oral mucosal lesions could get more complete, and then we could decrease the incidence of oral cancer.
目 錄
中文摘要
英文摘要
頁碼
第一章緒論………………………………………………..1
第二章文獻探討…………………………………………..3
第三章材料與方法
(1)研究對象……………………………………………11
(2)研究方法……………………………………………11
(3)分析方法……………………………………………12
第四章研究結果………………………………………….14
第五章討論……………………………………………….22
參考文獻……………………………………………………...26
表(表1~21)
附件(附件一~六)
參考文獻
1.衛生統計(一)公務統計,行政院衛生署,41-50,1999.
2.衛生統計(一)公務統計,行政院衛生署,71-79,1999.
3.王東堯:談「口腔檳榔癌」。防癌雜誌,26-27;6,1993.
4.國際口腔保健研討會論文集。行政院衛生署中部辦公室,122,1999。
5.郭彥彬:有關檳榔嚼塊引發口腔疾病的研究。健康世界,31-34;9,1997.
6.賴德榮:口腔黏膜下纖維化症之臨床療法評估與實驗性誘導病灶
之研究。高雄醫學院,博士論文;371995.
7.PINDBORG JJ SIRSAT SM. Oral submucous fibrosis. Oral Surg Oral Med Oral Pathol.22:764-79;1996.
8.SHIAU YY, KWAN HW. Submucous fibrosis in Taiwan. Oral Surg. 47:453-7;1979.
9.MURTI PR, BHONSLE RB, GUPTA PC. Etiopathogenesis of oral submucous fibrosis. Symposium on betel quid chewing and its health effect. Abstr 4:Kaohsiung, Taiwan;1993.
10.IARC.:Betel-quid and areca-nut chewing. International Agency for research Cancer. Lyon, Monographs. 12:634-640; 1986.
11.Vigneswarn N, Tilashalsik K, Rodu B, Cole P.: Tobacco use and cancer. A reappraisal, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontics.80:178-82;1995.
12.Hecht SS, Peterson LA,, Spratt TE: Tobacco-Specific nitrosamines, IARC Scientific Publications.125:73-89;1994.
13.Thomas SJ, MacLennan R.: Slaked Lime and Betel nut cancer in Papua New Guinea. Lancer.340(8819):577-8;1992.
14.Dave BJ, Trivedi AH, Adhvaryu SG.: Tole of areca nut consumption in the cause of oral cancers. A cytogeneic assessment. Cancer.70:1017-23;1992.
15.IARC.:Betel-quid and areca-nut chewing. International Agency for research Cancer. Lyon, Monographs. 37:141-291; 1985.
16.韓良俊。紅唇心事─檳榔危害知多少。806-811;10,1997.
17.LU CT, Lan SJ, Hsieh CC, Yang MJ, Ko YC, Tsai CC, Yen YY: Prevalence and characteristics of areca nut chewers among junior high school students in Changhua county, Taiwan. Community Dent Oral Epidemiol 21:261-264,1992.
18.李蘭,晏涵文,劉潔心,關學婉,季瑋珠,林瑞雄:嚼檳榔預防
教育先驅研究(I)-國中生嚼檳榔現況及影響因素之初探。中華
醫誌。11:285-94;1992.
19.李蘭,晏涵文,劉潔心,陳麗鳳:嚼檳榔預防教育先驅研究(II)
-國中生嚼檳榔現況及影響因素之初探。中華醫誌。11:295-303; 1992.
20.嚴道:台灣地區青少年對吸菸、飲酒、嚼檳榔之認知、態度、行
為與其心裡特質調查研究。行政院衛生署研究計畫成果報告,台
北,1994.
21.Ko YC, Chiang TA, Chang SJ, Hsieh SF: Prevalence of betel
quid chewing habit in Taiwan and related sociodemographic
factors. J Oral Pathol Med 25:261-64;1992.
22.劉碧華:台灣某山地鄉原住民吸菸、喝酒及吃檳榔之盛行率調查與相關因素之探討。高雄醫學院,碩士論文,79-92,1993.
23.李秀玉;牡丹鄉鄉民嚼食檳榔、抽菸、喝酒之現況及口腔黏膜病
變之研究。高雄醫學院,碩士論文;16-26,1998.
24.陳碧玉:台灣中部地區中老年人口腔健康相關因素探討。高雄醫學院,碩士論文;68,1994.
25.張家豪:台灣北、東地區中老年人口腔健康調查狀況與分析。高雄醫學院,碩士論文;14-15,1997.
26.Mani NJ:Studies on oral submucous fibrosis. IV. Connective tissue changes. Journal of Oral Medicine, 32:70-74,1997.
27.Hammen III JE, Mehta FS, Pindborg JJ and Daftany DK: Altered staining reaction of connective tissue in 53 submucous fibrosis patients, Journal of Dental Research, 50,1971.
28.Sirsat SM and Pindborg JJ: Subepthelial changes in oral submucous fibrosis. Acta Pathologica et Microbiologica Scandinavica, 70,1967.
29.Mani NJ, Singh B: Studies on oral submucous fibrosis. Oral Surgery, Oral Medicine and Oral Pathology, 41,1976.
30.周明哲:臨床口腔診斷篇。臨床牙科寶鑑。(4),6-32;台北市牙醫師公會。12,1995.
31.黃湧澧:檳榔粹取液對誘癌劑(DMBA)誘發倉鼠頰黏膜鱗狀上皮
細胞癌之研究。高雄醫學院,碩士論文;4-6,1989.
32.Sinor PN, Gupta PC Murti PR, Bhonsle RB, Daftary DK, Mehta
FS, Pindborg JJ:A case-control study of oral submucous
fibrosis with special reference to the etilolgic role of
areca nut. J Orla Pathol Med.19: 94-8;1990.
33.國際口腔保健研討會論文集。行政院衛生署中部辦公室,117-124,1999.
34.Meghji S, Scutt A, Harvey W and Canniff JP: An in-vitro comparison of human fibroblast, from normal and oral submucous fibrosis tissue. Archives of Oral Biology, 32, 1987.
35.Harvey W, Scult A, Meghji S and Caff JP: Stimulation of human buccal mucosa fibroblasts in vitro by betel-nut alkaloids. Archives of Oral Biology, 31, 1986.
36.賴德榮:倉鼠之口腔頰袋黏膜癌化過程中致癌與促癌作用之研究。高雄醫學院牙醫學研究所碩士論文。1998.
37.林立民、陳玉昆、黃湧灃:適當濃度之Arecaidine對誘癌劑(DMBA)誘發倉鼠頰黏膜鱗狀上皮細胞過程中促癌效應之研究。第一屆嚼食檳榔之健康影響國際研討會論文摘要。1993.
38.Holmstrup P,Thorn JJ, Tindum,et al: Malignant development of lichen planus affected oral mucosa. J Oral Pathol; 17:219-225, 1988.
39.中華民國家庭牙醫學會:社區口腔健康照顧與發展。台灣省政府
衛生處;117-137,1998.
40.楊奕馨:檳榔相關口腔癌前病變之流行病學研究。論壇健康促進與疾病預防委員會文獻回顧研析計畫。國家衛生研究院論壇健康促進與疾病預防委員會,9-18;5,2000.
41.Gupta PC, Mehta FS, Pindborg JJ, Aghi MB, Bhonsle RB, Daftary
DK, Murti PR, Shah HT: Intervention study for primary
prevention fo oral cancer among 36000 Indian tobacco user.
Lancet.1: 1235-8;1986.
42.Gupta PC, Mehta FS, Pindborg JJ, Aghi MB, Bhonsle RB,
Daftary DK, Murti PR: Primay prevention trial of orla cancer
in India: a 10-year follow-up study, J Oral Pathol Med.21: 433-9;1992.
43.Chang KM: Betel nut Chewing and mouth cancer in Taiwan. J
Formosan Med Assoc.63: 437-48;1964.
44.Kwan HW: A statistical study on oral carcinomas in Taiwan
with cmphasis on the relationship with betel nut chewing: a
preliminary report. J Formosan Med Assoc. 75: 497-505;1976.
45.陳至興,林清榮,張斌:234例口腔癌的統計與分析。中華民國
耳鼻喉科醫學會雜誌,19:20-5;1984.
46.李果,黃穰基,張佑良,張哲壽:口腔鱗狀上皮細胞轉移之分析
研究。中華醫誌。48:445-50;1991.
47.Lu CT, Yen YY, Ho CS, Ko YC, Tsai CC, Hsieh CC, Lan SJ: A
case-control study of orla cancer in Changhua County, Taiwan.
J Oral Pathol Med. 25: 245-8;1996.
48.Huang YL, Lin LM, Lin CC, Shieh YT: Oral submucous fibrosis
(precancerouslesion) in sounthern Taiwan. Abstracts of the
14th Annual Session Associ for Dent Sci;9:27,1990.
49.Chen CH: An Epidemiological study of oral squamous cell
carcinoma in southern Taiwan.J Formosan Dent Assoc ; 10:
268-74;1987.
50.陳金勝,陳中和:口腔鱗狀上皮細胞癌之統計分析報告。高醫雜
誌。11:582-8;1995.
51.Chen YK, Huang HC, Lin LM, Lin CC: Primary oral squamous cell
carcinoma: an analysis of 703 cases in Southern Taiwan. Oral
Oncology. 35:173-9;1999.
52.Ko YC, Huang YL, Lee CH, Chen MJ, Lin LM, Tsai CC: Betel quid
chewing, cigarette smoking and alcohol consumption related
of oral cancer in Taiwan. J OralPathol Med. 24:450-3;1995.
53.黃顯成:高雄醫學院口腔組織病理標本分析研究(1985-1996)--含口腔癌病患之存活率及放射線影像相關分析。高雄醫學院,碩士論文,1998.
54.Zain RB, Ikeda N, Razak, IA, Axell, T, Majid, ZA, Gupta, PC, Yaacob, M: A national epidemiological survey of oral mucosal lesions in Malaysis. Community Dent Oral Epidemiol, 25:377-393,1997.
55.World Health Organization: Oral Health Surveys-Basic
Mehtods. 4th ed. Geneva, 1997.
56.勞工安全衛生法,勞工健康保護規則;1-9.
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