在醫學及生物力學的應用上，腳底壓力的分佈是個辨別疾病的重要特徵；人類的步態會因為個體特性的差異而有所不同，醫師便可藉由步態的生理訊號分析以瞭解發病的原因，並診斷患者的狀況。大多數的步態研究，都是由醫院或專業的步態分析研究室應用市面上的腳底壓力量測系統商品，來分析腳底壓力與病症間的關係；但系統價格過於昂貴，並無法普遍地讓一般大眾擁有及使用。另外，在參考文獻上所提及的腳底壓力量測系統，其壓力點的解析度都過低，每腳僅量測7或12個壓力點，並無法完整地監測腳底壓力資料。在成本及高解析度的考量下，採用越來越普及的個人數位助理以及高解析度的腳壓墊來建立此系統。
因此，本論文的主要目的，在於建立一套以個人數位助理為基礎的腳底壓力量測系統。本系統使用TrgPro Palm Pilot當作系統的控制以及儲存單元，此個人數位助理的CPU時脈速度為20MHz，透過其內建的CompactFlash介面輸出控制碼，驅控CF_8255 IO卡對擷取電路進行控制及訊號擷取的動作；擷取電路是使用多工器、放大器以及類比/數位轉換電路來建構，透過多工器選擇所要量測的腳底壓力點，此壓力點的足底壓力資料便經腳壓墊換能器轉換為電阻值，再經過放大器、類比/數位轉換電路的處理而成為數位訊號，最後讀回個人數位助理內儲存。
本論文的研究成果，建立了可攜式、低成本、高解析度的腳底壓力量測系統：(1)以電池供應系統電源，配合個人數位助理小巧的特性，可以克服地形上的限制；(2)採用Tekscan Inc.的腳壓墊換能器，其解析度最高為每腳960個壓力點，配合並列埠進行大量的資料傳輸，建立高解析度的機制；(3)扣除了個人數位助理以及軟體的費用，可建立低成本的腳底壓力量測系統。此外，本系統的擷取速度可達到每秒11,520個壓力點數值的量測。研究的結果顯示，以個人數位助理為基礎，來建立一可攜式的生理訊號擷取裝置是可行的方式；利用個人數位助理本身的輕便、可攜、實用等特性，以及其並列埠介面，再加上低成本建立的硬體電路，便可發展出經濟實用的可攜式生理訊號擷取裝置，讓大多數的人都可以容易地擁有及使用。

The distribution of plantar pressure is an important characteristic to identify diseases such as peripheral neuropathy, plantar ulcer, varus, talipes valgus, flat-footed, etc. Patients with polyneuropathy often lose sensation of pain at their feet. They are high-risk groups for developing neuropathic ulcers on the plantar surface of their feet. That may lead to lower extremity amputation. Using plantar pressure evaluation system, physicians are able to monitor the improvement of patient’s illness. Furthermore, most researchers in gait study utilize the plantar pressures acquisition systems to identify the relationship between plantar pressures and diseases. These commercial plantar pressures acquisition are expensive. In addition, the existing plantar pressures acquisition systems also have the problem of low resolution. These systems only can detect 7 or 12 pressure points at one foot.
Considering the cost and the resolution, the purpose of this research is to develop a PDA-based plantar pressures acquisition system. The designed system utilizes the TrgPro Palm PilotTM as the unit of controlling system and storing data. The device operates at a crystal clock frequency of 20MHz. The CompactFlashTM interface of PDA is utilized to output control code and acquire data. The plantar pressure sensor insole has 960 independent pressure points. The applied pressure to the sensor of insole decreases its resistance, which causes the output voltage of the amplifier circuit to increase. A set of multiplexer is used to activate the selected pressure point at insole for acquisition. The PDA acquires digital voltage data from the A/D converter and stores the data into database. A software program that will evaluate the serial gait patterns with distribution and magnitudes of plantar pressure. The program also calculates the parameters for gait analysis, such as gait cycle, peak value of pressure, center of pressure, etc.
In summary, this thesis has developed a portable, low-cost and high-resolution plantar pressures acquisition system. This system utilizes batteries for power supply. And, the system also utilizes the characteristics of lightweight PDA as a portable system. The design takes advantage of CompactFlashTM interface as parallel port for transporting a large quantity of data to establish the characteristic of temporal high resolution. As well as high spatial resolution, the sampling rate of a pressure point is 11,520Hz. The future development should be focused on improving the sampling rate of a pressure point, reducing the size of acquisition system and the weight of batteries. Then, the designed PDA-based plantar pressures acquisition system can be commercialized and meet the clinical requirement to aid patients and the general of people.

第一章 緒論
1.1 前言
1.2 研究動機與目的
1.3 論文架構
第二章 背景
2.0 本章概述
2.1 生理訊號擷取儀器的架構
2.2 腳底壓力量測方法
2.3 壓力感測裝置
2.4 腳底壓力量測系統
2.5 PDA的發展簡史
2.6 PDA在醫學上的應用與介面
2.7 腳底壓力的起源與研究
2.7.1 步態研究的起源
2.7.2 腳底壓力的步態研究
第三章 系統架構及方法
3.0 本章概述
3.1 系統組成
3.2 硬體的規劃
3.3 個人數位助理與CF介面
3.3.1 個人數位助理
3.3.2 CF介面
3.4 腳壓墊換能器
3.5 CF_8255 IO 電路
3.5.1 8255 IC
3.5.2 位址解碼器
3.5.3 資料緩衝器
3.6 選擇與訊號處理電路
3.6.1 選擇電路
3.6.2 訊號擷取電路
3.6.3 類比/數位轉換電路
3.6.4 取樣率產生器
3.7 軟體的規劃
3.8 腳底壓力訊號擷取程式架構
3.8.1 腳底壓力訊號擷取程式開發平台
3.8.2 Palm與CF介面的連結
3.8.3 CF Slot介面的位址換算
3.8.4 訊號的輸出、讀取與儲存
3.9 腳底壓力訊號處理程式架構
3.9.1 開檔
3.9.2 繪圖
3.9.3 影像處理
3.9.4 正規化
3.9.5 C.O.P (Center Of Pressure)
第四章 系統校準及測試結果
4.0 本章概述
4.1 儀器設備
4.2 系統校準
4.3 系統實際測試
4.4 實驗設計
4.5 實驗結果
5.1 量測壓力的範圍
5.2 擷取速度的討論
5.3 腳底壓力的參數
第六章 結論與未來展望
6.0 本章概述
6.1 結論
6.2 未來展望
參考文獻
附錄一

[1] MacWilliams, B.A.; Armstrong, P.F., ”Clinical applications of plantar pressure measurement in pediatric orthopedics,” Pediatric Gait, 2000 Page(s): 143 -150[2] Sacco, I.C.N.; Amadio, A.C., “A study of biomechanical parameters in gait analysis and sensitive cronaxie of diabetic neuropathic patients.” Clinical Biomechanics , Volume:15, Issue:3, March, 2000, pp. 196-202[3]行政院衛生署網頁資料, http://www.doh.gov.tw/ ,2001 [4] Scarlet, J.J.; Blais, M.R., “Statistics on the diabetic foot.” J Am Podiatric Medical Association 1989;79:306-7.[5] Levin, M.E., “Medical evaluation and treatment,” The Diabetic Foot, M.E. Levin and L.W. O’Neil, Eds. St. Louis, MO: C. V. Mosby Co., 1983, pp.1-61.[6] Siitonen, O.I.; Niskanen, L.K.; Laakso, M., “Lower extremity amputation in diabetic and non diabetic patients: a population-based study in eastern Finland.” Diabetic Care 16, 16-20, 1993.[7] Most, R.; Sinnock, P., “The epidemiology of lower extremity amputations in diabetic individuals.” Diabetes Care 1, 185-191, 1983.[8]世界衛生組織(WHO)網頁資料，http://www.who.int/home-page/ , 2001.[9] Boulton, A.J.M.; Franks, C.I.; Betts, R.P. et al., “Reduction of abnormal foot pressures in diabetic neuropathy using a new polymer insole material.” Diabetes Care 7,42, 1984.[10] Fleischli, J.G.; Lavery, L.A.; Vela, S.A.; Ashry, H.; Lavery, D.C., “Comparison of strategies for reducing pressure at the site of neuropathic ulcers.” Journal of Amreican Podiatric Medical Assocication 87, pp. 466-472, 1997.[11] Zhu, H.; Haris, G.F.; Wertsch, J.J.; Tompkins, W.J.; Webster, J.G., “A microprocessor-based data-acquisition system for measuring plantar pressures from ambulatory subjects”, IEEE Trans. Biomed. Eng., vol. 38, pp. 710-714, July 1991.[12] Zou, Yonging; Guo, Zhenyu, “A Palm Pilot Based Pocket ECG Recorder”, IEEE International Conference on EMBS, 2000, Page(s): 110 —112[13]黃炳璋”人體平衡控制定量評估、系統鑑別及可攜帶式動態腳壓量測系統實體開發”，長庚大學機械工程研究所碩士論文，民國87年。[14]余能堅,”生理訊號擷取分析系統模組化之設計”，中原大學醫學工程所碩士論文，民國89年。[15] Welton, E.A., “The Harris and Beath footprint: interpretation and clinical value.” Foot Ankle, vol. 13, pp. 462-268, Oct, 1992.[16] Acor orthopaedic, Inc. http://www.acor.com/ ,2001.[17] Zhu, H.; Maalej, N.; Webster, J.G.; Tompkins, W.J.; Bach-y-Rita, P.; Wertsch, J.J., “An umbilical data-acquisition system for measuring pressures between the foot and shoe,” IEEE Trans. Biomed. Eng., vol. 37, pp. 908-911, Sept. 1990.[18] Novel electronics inc. http://www.novel.de/ ,2001.[19] Interlink Electronics, Inc. http://www.interlinkelec.com/indexf.html, 2001[20] Yip, S.W.; Prieto, T.E., “A system for force distribution measurement beneath the feet.” Biomedical Engineering Conference, 1996., Proceedings of the 1996 Fifteenth Southern , 1996 Page(s): 32 -34[21] Tekscan, Inc. http://www.tekscan.com/ , 2001.[22] Steadlands International Marketing Ltd. http://www.steadlands.com/fsr.htm, 2001.[23] Morley, R.E., Jr.; Richter, E.J.; Klaesner, J.W.; Maluf, K.S.; Mueller, M.J. “In-shoe multisensory data acquisition system.” Biomedical Engineering,” IEEE Transactions on Volume: 48 Issue: 7, July 2001, Page(s): 815 —820.[24] Zhu, H.; Harris, G.F.; Wertsch, J.J.; Tompkins, W.J.; Webster, J.G., “A microprocessor-based data-acquisition system for measuring plantar pressures from ambulatory subjects.” Biomedical Engineering, IEEE Transactions on , Volume: 38 Issue: 7 , July 1991 Page(s): 710 —714[25] Zhu, H.; Wertsch, J.; Harris, G.F.; Price, M.B.; Alba, H.M. “Pressure distribution beneath sensate and insensate feet.” Engineering in Medicine and Biology Society, 1989. Images of the Twenty-First Century., Proceedings of the Annual International Conference of the IEEE Engineering in , 1989 Page(s): 822 -823 vol.3[26] Zhu, H.; Maalej, N.; Webster, J.G.; Tompkins, W.J.; Bach-y-Rita, P.; Wertsch, J.J., “A microprocessor-based data-acquisition system for monitoring foot pressures.” Engineering in Medicine and Biology Society, 1988., Proceedings of the Annual International Conference of the IEEE , 1988 Page(s): 1599 -1600 vol.4[27] Abu-Faraj, Z.U.; Harris, G.F.; Wertsch, J.J.; Abler, J.H.; Vengsarkar, A.S., ”Holter system development for recording plantar pressures: design and instrumentation.” Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers., Proceedings of the 16th Annual International Conference of the IEEE , 1994 Page(s): 934 -935 vol.2[28] Vengsarkar, A.S.; Abler, J.H.; Abu-Faraj, Z.U.; Harris, G.F.; Wertsch, J.J. “Holter system development for recording plantar pressures: software development.” Engineering in Medicine and Biology Society, 1994. Engineering Advances: New Opportunities for Biomedical Engineers., Proceedings of the 16th Annual International Conference of the IEEE , 1994, Page(s): 936 -937 vol.2[29] Wervey, R.A.; Abler, J.H.; Abu-Faraj, Z.U.; Harris, G.F.; Wertsch, J.J,. “Data preview software for interactive review of Holter type plantar pressure data.” Engineering in Medicine and Biology Society, 1995., IEEE 17th Annual Conference , Volume: 2 , 1995 Page(s): 1279 -1280 vol.2[30] Abu-Faraj, Z.O.; Harris, G.F.; Abler, J.H.; Wertsch, J.J.; Smith, P.A. “A Holter-type microprocessor-based rehabilitation instrument for acquisition and storage of plantar pressure data in children with cerebral palsy,” Rehabilitation Engineering, IEEE Transactions on , Volume: 4 Issue: 1 , March 1996 Page(s): 33 —38[31] Abu-Faraj, Z.O.; Harris, G.F.; An-Hsiung Chang; Shereff, M.I. “Evaluation of a rehabilitative pedorthic: plantar pressure alterations with scaphoid pad application.” Rehabilitation Engineering, IEEE Transactions on [see also IEEE Trans. on Neural Systems and Rehabilitation Engineering] , Volume: 4 Issue: 4 , Dec. 1996 Page(s): 328 —336[32] Abu-Faraj, Z.O.; Harris, G.F.; Smith, P.A. “Surgical rehabilitation of the planovalgus foot in cerebral palsy.” Neural Systems and Rehabilitation Engineering, IEEE Transactions on [see also IEEE Trans. on Rehabilitation Engineering] , Volume: 9 Issue: 2 , June 2001 Page(s): 202 —214[33] Pataky, Zoltan; Faravel, Luc; Da Silva, José; Assal, Jean-Philippe “A new ambulatory foot pressure device for patients with sensory impairment.” Journal of Biomechanics, Volume: 33, Issue: 9, September, 2000, pp. 1135-1138.[34]張致仁編著， “Palm OS 3.5 程式設計速成”,儒林圖書有限公司,台北市, 2000.[35]張世雄，”利用個人數位助理之平行埠擷取生理訊號之研發”，中原大學醫學工程所碩士論文，民國90年。[36]林啟禎醫師，腦性麻痺之家網頁資料，http://140.116.60.95/~mark/index.htm , 2002.[37]呂東武，”步態分析技術發展現況與未來趨勢” ，國立台灣大學生物技術研究中心-生物醫學報導第五期，January 2001.[38]李明義，”人體步行動態平衡反應評估-蝴蝶狀重心晃動曲線分析比較”，中華醫學工程學刊，Vol.20 No.3, September 2000. pp.167-176.[39]詹益坤， ”義足型式與校準量的選擇研究”，國立陽明大學醫學工程研究所碩士論文，民國86年。[40]李志韋，” 穿鞋行走時足部之生物力學探討”， 國立成功大學醫學工程研究所碩士論文，民國88年。[41]龍希文、羅致遠、楊世偉，”轉彎型態對於足底壓力的影響”，中華醫學工程學刊，Vol.19 No.2, June 1999.[42]張名凱，”下肢截肢者之步態與義肢校正量分析”， 國立陽明大學醫學工程研究所碩士論文，民國84年。[43]劉心儀， ”以足底壓力參數評估痙攣型腦性麻痺孩童穿著鞋墊式矯正鞋之效益”，國立陽明大學醫學工程研究所碩士論文，民國88年。[44]石正偉， ”唐氏症兒童穿著具足弓墊之矯正鞋步行能力之效益評估”，國立陽明大學醫學工程研究所碩士論文，民國90年。[45]許盛發， ”鞋墊對減低足底壓力效益之生物力學分析”，國立陽明大學醫學工程研究所碩士論文，民國85年。[46]李豪政，” 活塞式鞋墊對減低足部壓力之效益研究” ，國立陽明大學醫學工程研究所碩士論文，民國89年。[47]長庚紀念醫院-復健科學及工程服務中心網頁資料，http://www.cgmh.org.tw/intr/intr2/c3390/re_en_sc.htm, 2002.[48]Don Anderson, “PCMCIA SYSTEM ARCHITECTURE”, 艾迪生維斯理出版有限公司， 台北市， 2000.[49] HandEra corp, “Development Kit for the TRGpro Handheld computer”, http://www.handera.com/, 2000.[50]Power Quotient International CO. ,Ltd. “PQI Flash Product Data sheet” , http://www.pqi.com.tw/, 2000.