|
參考文獻 Achenbach TV., Slater EP., Brummerhop H., Bach T., and Muller R. Inhibition of cyclin-dependent kinase activity and induction of apoptosis by preussin in human tumor cells. Antimicrob. Agents Chemother. 44:2794-2801, 2000. Anthony MS. Soy and cardiovascular disease: cholesterol lowering and beyond. J Nutr., 130:662-663, 2000. Aden DP., Fogel A., Plotkin S., Damjanov I., and Knowles BB. Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature. 282:615-616, 1979. Adlercreutz H., Honjo H., Higashi A., Fotsis T., Hamalainen E., Hasegawa T., and Okada H. Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet. Am. J. Clin. Nutr. 54:1093-1100, 1991. Agarwal R. Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. Biochem Pharmacol., 60:1051-1059, 2000. Alnemri ES., Livingston DJ., Nicholson DW., Salvesen G., Thornberry NA., Wong WW., and Yuan J. Human ICE/CED-3 protease nomenclature. Cell. 87:171, 1996. Ando T., Kawabe T., Ohara H., Ducommun B., Itoh M., and Okamoto T. Involvement of the interaction between p21 and proliferating cell nuclear antigen for the maintenance of G2/M arrest after DNA damage. J Biol Chem., 276:42971-42977, 2001. Anderson HJ., Coleman JE., Andersen RJ., and Roberge M. Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation. Cancer Chemother. Pharmacol. 39:223-226, 1997. Beato M. Gene regulation by steroid hormones. Cell. 56:335-44, 1989 Blasina A., de Weyer IV., Laus MC., Luyten WH., Parker AE., McGowan Casagrande F., and Darbon JM. P21CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells. Exp Cell Res., 258:101-108, 2000. Blasina A., de Weyer IV., Laus MC., Luyten WH., Parker AE., and McGowan CH. A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase. Curr. Biol. 4: 1-10, 1999. Boise LH., Gonzalez-Garcia M., Postema CE., Ding L., Lindsten T., Turka LA., Mao X., Nunez G., and Thompson CB. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 74:597-608, 1993. Bruix J., and Llovet JM. Prognostic prediction and treatment strategy in hepatocellular carcinoma. Hepatology. 35:519-524, 2002. Brown A., Jolly P., and Wei H. Genistein modulates neuroblastoma cell proliferation and differentiation through induction of apoptosis and regulation of tyrosine kinase activity and N-myc expression. Carcinogenesis. 19:991-997, 1998. Bunz F., Dutriaux A., Lengauer C., Waldman T., Zhou S., Brown JP., Sedivy JM., Kinzler KW., and Vogelstein B. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science. 282:1497-1501, 1998. Busse PM., Bose SK., Jones RW., and Tolmach LJ. The action of caffeine on X-irradiated HeLa cells. III. Enhancement of X-ray-induced killing during G2 arrest. Radiat. Res. 76:292-307, 1978. Casagrande F., and Darbon JM. P21CIP1 is dispensable for the G2 arrest caused by genistein in human melanoma cells. Exp. Cell Res. 258:101-108, 2000. Chan TA., Hermeking H., Lengauer C., Kinzler KW., and Vogelstein B. 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature. 401:616-620, 1999. Chaturvedi P., Eng WK., Zhu Y., Mattern MR., Mishra R., Hurle MR., Zhang X., Annan RS., Lu Q., Faucette LF., Scott GF., Li X., Carr SA., Johnson RK., Winkler JD., and Zhou BB. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene . 18:4047-4054, 1999. Allred CD., Allred KF., Ju YH., Virant SM., and Helferich WG. Soy Diets Containing Varying Amounts of Genistein Stimulate Growth of Estrogen-dependent (MCF-7) Tumors in a Dose-dependent Manner. Cancer Res. 61:5045-5050, 2001. Clarke DJ., and Gimenez-Abian JF. Checkpoints controlling mitosis. Bioessays. 22:351-363, 2000. Cliby WA., Roberts CJ., Cimprich KA., Stringer CM., Lamb JR., Schreiber SL., and Friend SH. Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J. 17:159-169, 1998. Clark JW., Santos-Moore A., Stevenson LE., and Frackelton AR Jr. Effects of tyrosine kinase inhibitors on the proliferation of human breast cancer cell lines and proteins important in the ras signaling pathway. Int. J. Cancer. 65:186-189, 1996. Constantinou A., Kiguchi K., and Huberman E. Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein. Cancer Res. 50:2618-2624, 1990. Curman D., Cinel B., Williams DE., Rundle N., Block WD., Goodarzi AA., Hutchins JR., Clarke PR., Zhou BB., Lees-Miller SP., Andersen RJ, and Roberge M. Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine. J. Biol. Chem. 276:17914-17919, 2001. Cynthia M., Simbulan-Rosenthal., Dean S. Rosenthal, Sudha Iyer, A. Hamid Boulares., and Mark ES. Transient Poly(ADP-ribosyl) ation of Nuclear Proteins and Role of Poly(ADP-ribose) Polymerase in the Early Stages of apoptosis.J. Biol. Chem. 273:13703-13712, 1998. Dalu A., Haskell JF., Coward L., and Lamartiniere CA. Genistein, a component of soy, inhibits the expression of the EGF and ErbB2/Neu receptors in the rat dorsolateral prostate. Prostate. 37:36-43, 1998. Davidovic L., Vodenicharov M., Affar EB., and Poirier GG. : Importance of poly (ADP-ribose) glycohydrolase in the control of poly (ADP-ribose) metabolism. Exp. Cell. Res. 268:7-13, 2001. Darbon JM., Penary M., Escalas N., Casagrande F., Goubin-Gramatica F., Baudouin C., and Ducommun B. Distinct Chk2 activation pathways are triggered by genistein and DNA-damaging agents in human melanoma cells .J. Biol. Chem. 275:15363-15369, 2000. Davis JN., Kucuk O., and Sarkar FH.Genistein inhibits NF-kappa B activation in prostate cancer cells. Nutr. Cancer. 35:167-174, 1999. Ding Z., Parchment RE., LoRusso PM., Zhou JY., Li J., Lawrence TS., Sun Y., and Wu GS.The investigational new drug XK469 induces G(2)-M cell cycle arrest by p53-dependent and -independent pathways. Clin. Cancer Res. 7:3336-3342, 2001. Frey RS., Li., and Singletary KW. Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21 (waf/cip1), p27 (kip1), and Cdc25C expression. .Biochem. Pharmacol.61:979-789, 2001. Fotsis T., Pepper M., Adlercreutz H., Hase T., Montesano R., and Schweigerer L. Genistein, a dietary ingested isoflavonoid, inhibits cell Proliferation and in vitro angiogenesis. J. Nutr.125: 790-797, 1995. Frey RS., Li J., and Singletary KW. Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression. Biochem Pharmacol., 61:979-989, 2001. Guettier C., Ganne-Carrie N., Ziol M., Arotcarena R., Christidis C., and Beaugrand M. Looking for large-cell dysplasia in liver needle biopsies how and why? Ann Pathol., 21:137-144, 2001. Gomez-Angelats M., Bortner CD., and Cidlowski JA. Cell volume regulation in immune cell apoptosis.Cell Tissue Res. 301:33-42, 2000. Hall-Jackson CA., Cross DA., Morrice N., and Smythe C.ATR is a caffeine- sensitive, DNA-activated protein kinase with substrate specificity distinct from DNA-PK. Oncogene. 18:6707-6713, 1999. Hsu JT., Jean TC., Chan MA., and Ying C. Differential display screening for specific gene expression induced by dietary nonsteroidal estrogen. Mol Reprod Dev., 52:141-148, 1999. Hayashi A., Popovich KS., Kim HC., and de Juan E Jr. Role of protein tyrosine phosphorylation in rat corneal neovascularization. Graefes Arch Clin Exp Ophthalmol., 235:460-467, 1997. Harper JW., Elledge SJ., Keyomarsi K., Dynlacht B., Tsai LH., Zhang P., Dobrowolski S., Bai C., Connell-Crowley L., and Swindell E. Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell., 6:387-400, 1995. Hale AJ., Smith CA., Sutherland LC., Stoneman VE., Longthorne V., Culhane AC., and Williams GT. Apoptosis: molecular regulation of cell death. Eur. J. Biochem.237:884, 1996. Heneghan MA., and McFarlane IG. Current and novel immunosuppressive therapy for autoimmune hepatitis. Hepatology. 35:7-13, 2002. Hockenbery D., Nunez G., Milliman C., Schreiber RD., and Korsmeyer SJ. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature. 348:334-336, 1990. Jiang X.,Lim LY, Daly JW, Li AH, Jacobson KA, and Roberge M.Structure- activity relationships for G2 checkpoint inhibition by caffeine analogs. Int. J. Oncol. 16:971-978, 2000. Ji S., Willis GM., Frank GR., Cornelius SG., and Spurlock ME. Soybean isoflavones, genistein and genistin, inhibit rat myoblast proliferation, fusion and myotube protein synthesis. J Nutr., 129:1291-1297, 1999. Kim H., Peterson TG., and Barnes S. Mechanisms of action of the soy isoflavone genistein: emerging role for its effects via transforming growth factor beta signaling pathways. Am J Clin Nutr, 68:1418-1425, 1998. Kluck RM., Bossy-Wetzel E.,Green, DR., and Newmeyer DD.The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science. 275:1132-1136, 1997. Knowles BB., Howe CC., and Aden DP. Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science.209:497-499, 1980. Kondoh N., Wakatsuki T., Hada A., Shuda M., Tanaka K., Arai M., and Yamamoto M. Genetic and epigenetic events in human hepatocarcinogenesis. Int J Oncol., 18:1271-1278, 2001. Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 3:614-620, 1997. Kuida K., Zheng TS., Na S., Kuan C., Yang D., Karasuyama H., Rakic P., and Flavell RA. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature. 384:368-372, 1996. Lai MM. Hepatitis C virus proteins: direct link to hepatic oxidative stress, steatosis, carcinogenesis and more. Gastroenterology. 122:568-571, 2002. Le Rhun Y., Kirkland JB., and Shah GM. Cellular responses to DNA damage in the absence of Poly(ADP-ribose) polymerase. Biochem. Biophys. Res. Commun. 245:1-10, 1998. Lian F., Bhuiyan M., Li YW., Wall N., Kraut M., and Sarkar FH. Genistein-induced G2-M arrest, p21WAF1 upregulation, and apoptosis in a non-small-cell lung cancer cell line. Nutr. Cancer. 31:184-191, 1998. .Lowndes NF., and Murguia JR. Sensing and responding to DNA damage Curr. Opin. Genet. Dev. 10:17-25, 2000. Maya R., Balass M., Kim ST., Shkedy D., Leal JF., Shifman O., Moas M., Buschmann T., Ronai Z., Shiloh Y., Kastan MB., Katzir E., and Oren M. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. Genes Dev. 15:1067-1077, 2001. Matsuoka S., Huang M., and Elledge SJ. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science. 282:1893-1897, 1998. Martin-Cordero C., Lopez-Lazaro M., Pinero J., Ortiz T., Cortes F., and Ayuso MJ. Glucosylated isoflavones as DNA topoisomerase II poisons. J Enzyme Inhib., 15:455-460, 2000. Mesiano S., Katz SL., Lee JY., and Jaffe RB. Phytoestrogens alter adrenocortical function: genistein and daidzein suppress glucocorticoid and stimulate androgen production by cultured adrenal cortical cells. J Clin Endocrinol Metab., 84:2443-2448, 1999. Minemoto Y., Gannon J., Masutani M., Nakagama H., Sasagawa T., Inoue M., Masamune Y., and Yamashita K. Characterization of adriamycin-induced G2 arrest and its abrogation by caffeine in FL-amnion cells with or without p53. Exp. Cell. Res. 262:37-48, 2001. Miyashita T., and Reed JC. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood. 81:151-157, 1993. Neamati N., Fernandez A., Wright S., Kiefer J., and McConkey DJ. Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei. J. Immunol. 154:3788-3795, 1995. Nicholson DW., Ali A., Thornberry NA., Vaillancourt JP., Ding CK., Gallant M., Gareau Y., Griffin PR., Labelle M., and Lazebnik YA. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 376:37-43, 1995. Nunez G., London L., Hockenbery D., Alexander M., McKearn JP., and Korsmeyer SJ. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol. 144:3602-3610, 1990. O'Connell MJ., Walworth NC., and Carr AM. The G2-phase DNA-damage checkpoint.Trends Cell Biol. 10:296-303, 2000. O'Conner PM., Ferris DK., Pagano M., Draetta G., Pines J., Hunter T., Longo DL., and Kohn KW. G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently. J. Biol. Chem., 268:8298-8308, 1993. Oltvai ZN., Milliman CL., and Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 4:609-619, 1993. O'Dell TJ., Kandel ER., and Grant SG. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature. 353:558-560, 1991. Poon RYC., Chau SM.,Yamashita K., and Hunter T. The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells. Cancer Res., 57:5168-5178, 1997. Peterson G. Evaluation of the biochemical targets of genistein in tumor cells. J. Nutr. 125:784-789, 1995. Poon RY., Chau MS., Yamashita K., and Hunter T. The role of Cdc2 feed- back loop control in the DNA damage checkpoint in mammalian cells. Cancer Res. 57:5168-5178, 1997. Rowley R., Zorch M., and Leeper DB. Effect of caffeine on radiation-induced mitotic delay: delayed expression of G2 arrest. Radiat. Res. 97:178-185, 1984. Russell KJ., Wiens LW., Demers GW., Galloway DA., Plon SE., and, Groudine M. Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint- competent cells. Cancer Res.,55:1639-1642,1995. Salti GI., Grewal S., Mehta RR., Das Gupta TK., Boddie AW Jr., and Constantinou AI. Genistein induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer cells. Eur J Cancer., 36:796-802, 2000. Sarkaria JN., Busby EC., Tibbetts RS., Roos P., Taya Y., Karnitz LM., and Abraham RT. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res. 59:4375-4382, 1999. Sarkaria JN., Busby EC., Tibbetts RS., Roos P., Taya Y., Karnitz LM., and Abraham RT. Inhibition of ATM and ATR kinase activities by the radio- sensitizing agent, caffeine. Cancer Res. 59, 4375-4382, 1999. Sathyamoorthy N., Gilsdorf JS., and Wang TT. Differential effect of genistein on transforming growth factor beta 1 expression in normal and malignant mammary epithelial cells. Anticancer Res., 18:2449-2453, 1998. Sadowska-Krowicka H., Mannick EE., Oliver PD., Sandoval M., Zhang XJ., Eloby-Childess S., Clark DA., and Miller MJ. Genistein and gut in- flammation: role of nitric oxide. Proc Soc Exp Biol Med., 217:351-357, 1998. Sanchez Y., Wong C., Thoma R.S., Richman R., Wu Z., Piwnica-Worms H., and Elledge SJ. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science. 277: 1497-1501, 1997. Savitsky K., Bar-Shira A., Gilad S., Rotman G., Ziv Y., Vanagaite L., Tagle DA., Smith S., Uziel T., and Sfez S. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science. 268:1749-1753, 1995. Sargeant P., Farndale RW., and Sage SO. ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets. J Biol Chem., 268:18151-18166, 1993. Schlegel R., and Pardee AB. Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells. Science. 232:1264-1266, 1986. Shieh SY., Ahn J., Tamai K., Taya Y., and Prives C. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 14:289-300, 2000. Steinman HM. The Bcl-2 oncoprotein functions as a pro-oxidant. Biol. Chem. 270:3487-3490, 1995. Su SJ., Yeh TM., Lei HY., and Chow NH. The potential of soybean foods as a chemoprevention approach for human urinary tract cancer. Clin. Cancer Res. 6:230-6236, 2000. Yao SL., Akhtra AJ., McKenna KA., Bedi GC., Sidransky D., Mabry M., Ravi R., Collector MI., Jones RJ., Sharskis SJ., Fucks EJ., and Bedi A. Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase. Nat. Med., 2:1140-1143, 1996. Tamura K., Southwick EC., Kerns J., Rosi K., Carr BI., Wilcox C., and Lazo JS. Cdc25 inhibition and cell cycle arrest by a synthetic thioalkyl vitamin K analogue. Cancer Res. 60:1317-1325, 2000. Tewari M., Quan LT., O'Rourke K., Desnoyers S., Zeng Z., Beidler DR., Poirier GG., Salvesen GS., and Dixit VM. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly (ADP-ribose) polymerase. Cell. 81:801-809, 1995. Tsujimoto Y. Stress-resistance conferred by high level of bcl-2 alpha protein in human B lymphoblastoid cell. Oncogene. 4:1331-1336, 1989. van der Schouw YT, de Kleijn MJ, Peeters PH, Grobbee DE. Phyto-oestrogens and cardiovascular disease risk. Nutr Metab Cardiovasc Dis., 10:154-67, 2000. Vaux DL., Cory S., Adams JM. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature. 335:440-442, 1988. Wang Y., Zhang X., Lebwohl M., DeLeo V., and Wei H. Inhibition of ultraviolet B (UVB)-induced c-fos and c-jun expression in vivo by a tyrosine kinase inhibitor genistein. Carcinogenesis. 19:649-654, 1998. Wang W., Higuchi CM., and Zhang R. Individual and combinatory effects of soy isoflavones on the in vitro potentiation of lymphocyte activation. Nutr Cancer.,;29:29-34, 1997. Wang TT., Sathyamoorthy N., and Phang JM. Molecular effects of genistein on estrogen receptor mediated pathways. Carcinogenesis. 17:271-275, 1996. Walters RA., Gurley LR., and Tobey RA. Effects of caffeine on radiation- induced phenomena associated with cell-cycle traverse of mammalian cells. Biophys. J., 14:99-118, 1974. White E. Life, death, and the pursuit of apoptosis. Genes Dev., 10:1-15, 1996. Wright JA., Keegan KS., Herendeen DR., Bentley NJ., Carr AM., and Hoekstra M.F, Concannon P. Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. Proc. Natl. Acad. Sci. U S A. 95:7445-450, 1998. Yeung LT, King SM, Roberts EA. Mother-to-infant transmission of hepatitis C virus. Hepatology. 34:223-229, 2001. Zava DT., and Duwe G. Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro. Nutr. Cancer. 31-40, 1997. Zampetti-Bosseler F., and Scott D. The effect of caffeine on X-ray-induced mitotic delay in normal human and ataxia-telangiectasia fibroblasts. Mutat. Res. 143:251-256, 1985. Zhou BB., and Elledge SJ. The DNA damage response: putting checkpoints in perspective. Nature.408:433-439, 2000. Zhang ZH., and Wang Q. Modulation of a cloned human A-type voltage-gated potassium channel (hKv1.4) by the protein tyrosine kinase inhibitor genistein. Pflugers Arch., 440:784-792, 2000. Zhang Y., Wang GJ., Song TT., Murphy PA., and Hendrich S. Urinary disposition of the soybean isoflavones daidzein, genistein and glycitein differs among humans with moderate fecal isoflavone degradation activity. J Nutr., 129:957-962, 1999. Zhou BB., Chaturvedi P., Spring K., Scott SP., Johanson RA., Mishra R., Mattern MR., Winkler JD., and Khanna KK. Caffeine abolishes the mammalian G2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. J Biol Chem. 275:10342- 10348, 2000.
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