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研究生:鍾依玲
研究生(外文):Yi-Ling Zhong
論文名稱:陰/陽離子液胞自發性形成之探討
論文名稱(外文):A Study on the Spontaneous Formation of Catanionic Vesicles
指導教授:張鑑祥張鑑祥引用關係馬哲儒馬哲儒引用關係
指導教授(外文):Chien-Hsiang ChangJer-Ru Maa
學位類別:碩士
校院名稱:國立成功大學
系所名稱:化學工程學系碩博士班
學門:工程學門
學類:化學工程學類
論文種類:學術論文
論文出版年:2002
畢業學年度:90
語文別:中文
論文頁數:85
中文關鍵詞:陰陽離子界面活性劑碳鏈對稱性陰/陽離子液胞
外文關鍵詞:catanionic surfactantalkyl chain length symmetrycatanionic vesicle
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本研究主要探討陰離子界面活性劑sodium dodecyl sulfate(SDS)與陽離子界面活性劑dodecyltrimethylammonium bromide(DTMAB),tetradecyltrimethylammonium bromide(TTMAB),或hexadecyl trimethylammonium bromide(HTMAB)所形成的三種具有不同碳鏈對稱性的陰/陽離子混合界面活性劑系統中,莫耳比例對自發性陰/陽離子液胞形成的影響。混合系統中微結構的生成,則是藉由粒徑及界面電位的測量與穿透式電子顯微鏡的觀察進行分析。
首先將陰、陽離子界面活性劑以等莫耳比例混合,並以威氏平板法測量在不同濃度下,混合溶液的平衡表面張力,測量結果顯示相較於單成份的界面活性劑而言,陰/陽離子混合界面活性劑降低表面張力的能力較佳。此外,在平衡表面張力對濃度的關係圖中所出現的明顯轉折點,應為由於混合界面活性劑的濃度超過其溶解度所造成。
在SDS/DTMAB混合系統中,易生成結晶物,自發性液胞的生成量較少,但SDS過量時,則有液胞或微胞生成。於SDS/TTMAB及SDS/HTMAB混合系統中,莫耳比例的改變使得混合系統形成透光度不等的混濁溶液,當陰、陽離子界面活性劑的混合比例遠離1/1時,混合溶液的濁度會降低,而粒徑量測結果顯示結晶的生成量減少,並轉而生成液胞。經過濾後的混合溶液中,自發性液胞的zeta 電位絕對值較大者,其粒徑亦較大,且SDS的莫耳比例增加時,液胞的zeta 電位會由正電位轉而變成負電位。在具有碳鏈對稱性的SDS/DTMAB混合系統中,則易有結晶出現,粒徑及界面電位測量結果顯示碳鏈對稱性不佳時,排列緊密如結晶的結構較不易產生,而會形成液胞或是微胞等微結構。
This study investigated the effects of composition on the spontaneous formation of catanionic vesicles in the mixed surfactant systems of an anionic surfactant, sodium dodecylsulfate (SDS), and a cationic surfactant, dodecyltrimethylammonium bromide (DTMAB), tetradecyltrimethyl- ammonium bromide (TTMAB), or hexadecyltrimethylammonium bromide (HTMAB). The formation of microstructures in the mixed surfactant systems was analyzed by the measurements of particle size and zeta potential and by the observation with transmission electron microscopy.
The mixed anionic/cationic surfactant systems with a molar ratio of 1:1 were prepared first, and their equilibrium surface tension behavior was studied by the Wilhelmy plate method. The results demonstrated that the mixed surfactants had a greater ability of lowering surface tension in comparison with that of single surfactants. Moreover, the significant slope changes in the equilibrium surface tension versus concentration curves were apparently due to the solubility limits of the mixed surfactants.
For the mixed SDS/DTMAB systems, crystallites easily formed over a wide range of compositions and the amount of spontaneously-formed vesicles was small. However, when the molar fraction of SDS was in excess of 0.5, only vesicles or micelles were detected. For the mixed systems of SDS with TTMAB or HTMAB, the turbidity of the mixtures strongly depended on the molar ratio of the single surfactants. When the molar fraction for one of the surfactants was higher than 0.5, the turbidity of the mixtures became lower and the transition from crystallites to vesicles or micelles was detected by particle size measurements. In the filtrated solutions of the mixtures, the spontaneously-formed vesicles with a higher absolute value of zeta potential were always found with a larger size. In addition, when the SDS molar fraction became higher, the zeta potential of the vesicles changed from positive values to negative ones. For the mixed SDS/DTMAB systems with symmetry in hydrocarbon chain length, it appears that compact structures, such as crystallites, could easily form. However, the particle size and zeta potential measurements indicated that for the mixed surfactants with asymmetry in hydrocarbon chain length, the dominant formation of vesicles or micelles resulted.
目 錄
中文摘要 I
Abstract II
誌 謝 IV
目 錄 V
表目錄 VII
圖目錄 VIII
符號說明 XIII
第一章 緒 論 1
1-1 前言 1
1-2文獻回顧 3
1-2-1 陰/陽離子界面活性劑的混合作用及特性 3
1-2-2 陰/陽離子液胞的形成 4
1-2-3 陰/陽離子液胞的穩定性 6
1-2-4 碳鏈對稱性對液胞形成的影響 8
1-3 研究動機與目的 9
第二章 實 驗 12
2-1 藥品 12
2-2 儀器及實驗裝置 12
2-2-1 威氏平板法表面張力儀(Wilhelmy plate tensiometer) 12
2-2-2 雷射光散射法粒徑測定儀 13
2-2-3雷射光散射法界面電位測定儀 14
2-2-4 穿透式電子顯微鏡(Transmission Electron Microscopy) 15
2-3 實驗步驟 16
2-3-1 混合界面活性劑溶液的平衡表面張力 16
2-3-2 液胞的粒徑分佈 17
2-3-3 液胞的界面電位 17
2-3-4 穿透式電子顯微鏡的觀察 18
第三章 結果與討論 25
3-1 陰/陽離子混合界面活性劑水溶液的界面特性 25
3-2 陰/陽離子液胞的形成 27
3-2-1 SDS/DTMAB混合系統 27
3-2-2 SDS/TTMAB混合系統 29
3-2-3 SDS/HTMAB混合系統 31
3-3 碳鏈對稱性對液胞形成的影響 34
第四章 結 論 76
參考文獻 78
自 述 85
Amante, J. C., Scamehorn, J. F. and Harwell, J. H., “Precipitation of mixtures of anionic and cationic surfactants: effect of surfactant structure, temperature, and pH,” J. Colloid Interface Sci. 144, 243, 1991.
Bergström, M. and Eriksson, J. C., “The energetics of forming equilibrated bilayer vesicles,” Langmuir 12, 624, 1996.
Blankschtein, D., Thurston, G. M. and Benedek, G. B., “Phenomenological theory of equilibrium thermodynamic properties and phase separation of micellar solutions,” J. Chem. Phys. 85, 7268, 1986.
Brasher, L. L., Herrington, K. L. and Kaler, E. W., “Electrostatic effects on the phase behavior of aqueous cetyltrimethylammonium bromide and sodium octyl sulfate mixtures with added sodium bromide,” Langmuir 11, 4267, 1995.
Chang, C. H. and Franses, E. I., “Adsorption dynamics of surfactants at the air/water interface: a critical review of mathematical models, data, and mechanisms,” Colloids and Surfaces A: Physicochem. Eng. Aspects 100, 1, 1995.
Chien C. L., Yang, Y. M., Chang, C. H. and Maa, J. R., “A study on cetyl pyridinium dodecyl sulfate and dodecyl trimethylammonium dodecyl sulfate catanionic surfactans,” J. Colloid Interface Sci., submitted, 2002.
Chiruvolu, S., Israelachvili, J. N., Naranjo, E., Xu, Z., Zasadzinski, J. A., Kaler, E. W. and Herrington, K. L., “Measurement of forces between spontaneous vesicle-forming bilayers,” Langmuir 11, 4256, 1995.
Crommelin, D. J. and Schreier, H., “Liposomes,” in Colloidal Drug Delivery Systems, J. Kreuter, Ed., Marcel Dekker, New York, 1994.
Day, H. D., Yang, Y. M. and Maa, J. R., “Synergism in SDDS-DDTMAC mixed surfactant system,” J. Chin. Inst. Chem. Engrs. 28, 229, 1997.
Dragćević, D., Bujan, M., Grahek, Ž. and Filipović-Vinceković, N., “Adsorption at the air/water Interface in dodecylammonium chloride/sodium dodecyl sulfate mixtures,” Colloid Polym. Sci. 273, 967, 1995.
Fattal, D. R., Andelman, D. and Ben-Shaul, A., “The vesicle-micelle transition in mixed lipid-surfactant systems: a molecular model,” Langmuir 11, 1154, 1995.
Fendler, J. H., Membrane Mimetic Chemistry, Wiley, New York, 1982.
Filipović-Vinceković, N. and Škrtić, D., “Counterion binding on mixed anionic/cationic micelles,” Colloid Polym. Sci. 266, 954, 1988.
Filipović-Vinceković, N. Bujan, M., Dragćević, D. and Nekić, N., “Phase behavior in mixtures of cationic and anionic surfactants in aqueous solution,” Colloid Polym. Sci. 273, 182, 1995.
Filipović-Vinceković, N., Bujan, M., Šmit, I., Tušek-Božić, Lj. and Štefanić, I., “Phase transitions from catanionic salt to mixed cationic/anionic vesicles,” J. Colloid Interface Sci. 201, 59, 1998.
Herrington, K. L. and Kaler, E. W., “Phase behavior of aqueous mixtures of dodecyltrimethylammonium bromide (DTAB) and sodium dodecyl sulfate (SDS),” J. Phys. Chem. 97, 13792, 1993.
Hsu, S. N. and Maa, J. R., “Foam Fractionation with Synergism,” Ind. Eng. Chem. Process Des. Dev. 24, 38, 1985.
Hua, X. Y. and Rosen, M. J., “Synergism in binary mixtures of surfactants. I. theoretical analysis,” J. Colloid Interface Sci. 90, 212, 1982.
Huang, J. B. and Zhao, G. X., “Formation and coexistence of the micelles and vesicles in mixed solution of cationic and anionic surfactant,” Colloid Polym. Sci. 273, 156, 1995.
Huang, J. B., Zhu, B. Y., Mao, M., He, P., Wang, J. and He, X., “Vesicle formation of 1:1 cationic and anionic surfactant mixtures in nonaqueous polar solvents,” Colloid Polym. Sci. 277, 354, 1999.
Huang, J. B., Yang, R., Zhu, B. Y., He, X. and Fu, H. L., “Vesicle formation of 1:1 cationic and anionic surfactant mixtures in N,N-dimethylformamide and tetrahydrofuran solutions,” Colloids and Surfaces A: Physicochem. Eng. Aspects 174, 403, 2000.
Israelachvili, J. N., “Aggregation of amphiphilic molecules into micelles, bilayers, vesicles and biological membranes,” in Intermolecular and surface forces, Academic Press, London, 1992.
Israelachvili, J. N., Mitchell, D. J. and Ninham, B. W., “Theory of self-assembly of hydrocarbon amphiphiles into micelles and bilayers,” J. Chem. Soc. Faraday Trans. 72, 1525, 1976.
Jeng, J. J., Maa, J. R. and Yang, Y. M., “Surface effects and mass transfer in bubble column,” Ind. Eng. Chem. Process Des. Dev. 25, 974, 1986.
Jönsson, B., Jokela, P., Khan, A., Lindman, B. and Sadaghiani, A., “Cataionic surfactants: phase behavior and microemulsions,” Langmuir 7, 889, 1991.
Kaler, E. W., Murthy, A. K., Rodriguez, B. E. and Zasadzinski, A. N., “Spontaneous vesicle formation in aqueous mixtures of single-tailed surfactants,” Science 245, 1371, 1989.
Kaler, E. W., Herrington, K. L. and Murthy, A. K., “Phase behavior and structures of mixtures of anionic and cationic surfactants,” J. Phys. Chem. 96, 6698, 1992.
Kondo, Y., Uchiyama, H., Yoshino, N., Nishiyama, K. and Abe, M., “Spontaneous vesicle formation from aqueous solutions of didodecyldimethylammonium bromide and sodium dodecyl sulfate mixtures,” Langmuir 11, 2380, 1995.
Lasic, D. D., “Liposome in drug delivery,” in Vesicles, M. Rosoff edited, Marcel Dekker, New York, 1996.
Lee, S. P., Yang, Y. M., Chang, C. H. and Maa, J. R., “The molecular interaction and synergism of a binary mixed surfactant system,” J. Chin. Colloid & Interface Soc. 20, 157, 1997.
Lianos, P. and Zana, R., “Micelle of tetradecyltriakylammonium bromides with fluorescent probes,”J. Colloid Interface Sci. 88, 594, 1982.
Lucassen-Reynders, E. H., Lucassen, J. and Giles, D., “Surface and bulk properties of mixed anionic/cationic surfactant systems,” J. Colloid Interface Sci. 81, 150, 1981.
Marques, E. F., “Size and stability of catanionic vesicles: effects of formation path, sonication, and aging,” Langmuir 16, 4798, 2000.
Meagher, R. J. and Hatton, T. A., “Enthalphy measurements in aqueous SDS/DTAB solutions using isothermal titration microcalorimetry,” Langmuir 14, 4081, 1998.
Mehreteab, A. and Loprest, F. J., “Formation of pseudo-nonionic complexes of anionic and cationic surfactants,” J. Colloid Interface Sci. 125, 602, 1988.
Mitsuishi, M. and Hashizume, M., “On the interaction of sodium alkyl sulfate with alkylpyridinium chloride and with alkyltrimethylammonium bromide in a solution,” Bull. Chem. Soc. Japan 46, 1946, 1973.
New, R. R. C., “Introduction,” in Liposomes: A Practical Approach, R.R.C. New, Ed., Oxford University Press, New York, 1990.
Regev, O. and Khan, A., “Alkyl chain symmetry effects in mixed cationic-anionic surfactant systems,” J. Colloid Interface Sci. 182, 95 1996.
Rosen, M. J., Surfactants and interfacial phenomena, Wiley, New York, 1989.
Salkar, R. A., Mukesh, D., Samant, S. D. and Nabigar, C., “Mechanism of micelle to vesicle transition in cationic-anionic surfactant mixtures,” Langmuir 14, 3778, 1998.
Stellner, K. L., Amante, J. C., Scamehorn, J. F. and Harwell, J. H., “Precipitation phenomena in mixtures of anionic and cationic surfactants in aqueous solutions,” J. Colloid Interface Sci. 123, 186, 1988.
Stokes, R. J. and Evans, D. F., “Amphiphilic systems-liquid-liquid interface,” in Fundamentals of Interfacial Engineering, Wiley-VCH, New York, 1997.
Sujatha, J. and Mishra, A. K., “Effect of ionic and neutral surfactants on the properties of phospholipid vesicles: investigation using fluorescent probes,” Journal of Photochemistry and Photobiology. A: Chemistry 104, 173, 1997.
Tajima, K., Nakamura, A. and Tsutsui, T., “Surface activity of complex in mixed surfactant solution,” Bull. Chem. Soc. Japan 52, 2060, 1979.
Talhout, R. and Engberts, B. F. N., “Self-assembly in mixtures of sodium alkyl sulfates and alkyltrimethylammonium bromides: aggregation behavior and catalytic properties,” Langmuir 13, 5001, 1997.
Tanford, C., “Micelle,” The hydrophobic effect: formation of micelles and biological membranes, Wiley Press, New York, 1980.
Tomašić, V., Filipović-Vinceković, N., Kojić-Prodić, B. and Kallay, N., “Precipitation and association in a mixture of dodecylammonium chloride and sodium dodecyl sulfate in aqueous medium,” Colloid Polym. Sci. 269, 1289, 1991.
Tomašić, V., Štefanić, I. and Filipović-Vinceković, N., “Adsorption, association and precipitation in hexadecyltrimethylammonium bromide/sodium dodecyl sulfate mixtures,” Colloid Polym. Sci. 277, 153, 1999.
Villeneuve, M., Kaneshina, S., Imae, T. and Aratono, M., “Vesicle-micelle equilibrium of anionic and cationic surfactant mixture studied by surface tension,” Langmuir 15, 2029, 1999.
Walker, S. A. and Zasadzinski, J. A., “Electrostatic control of spontaneous vesicle aggregation,” Langmuir 13, 5076, 1997.
Yatcilla, M. T., Herrington, K. L., Brasher, L. L. and Kaler, E. W., “Phase behavior of aqueous mixtures of cetyltrimethylammonium bromide (CTAB) and sodium octyl sulfate (SOS),” J. Phys. Chem. 100, 5874, 1996.
Yuet, P. K. and Blankschtein, D., “Molecular-thermodynamic modeling of mixed cationic/anionic vesicles,” Langmuir 12, 3802, 1996a.
Yuet, P. K. and Blankschtein, D., “Effect of surfactant tail-length asymmetry on the formation of mixed surfactant vesicles,” Langmuir 12, 3819, 1996b.
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