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研究生:歐建志
論文名稱:乳酸鹽對心室肌及肺靜脈心肌的作用
論文名稱(外文):Effects of Lactate on Ventricular Muscle and Pulmonary Vein Myocardial Cells
指導教授:林正一林正一引用關係
指導教授(外文):Lin CI
學位類別:碩士
校院名稱:國防醫學院
系所名稱:藥理學研究所
學門:醫藥衛生學門
學類:藥學學類
論文種類:學術論文
論文出版年:2002
畢業學年度:90
語文別:中文
中文關鍵詞:乳酸鹽
相關次數:
  • 被引用被引用:0
  • 點閱點閱:145
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乳酸鹽對心室肌及肺靜脈心肌的作用

目錄
目錄------------------------------------------------------------------------------- Ⅰ
圖目錄---------------------------------------------------------------------------- Ⅲ
中文摘要------------------------------------------------------------------------- 1
英文摘要------------------------------------------------------------------------- 4
緒論
第一節 心肌缺血的產物:乳酸-------------------------------------- 7
第二節 心房性心律不整的主凶之一:肺靜脈異位節律點----- 8
第三節 乳酸的介紹----------------------------------------------------- 10
第四節 離子流的簡介-------------------------------------------------- 11
實驗目的-------------------------------------------------------------------------- 14
材料和方法
第一節 實驗動物-------------------------------------------------------- 15
第二節 離體組織實驗------------------------------------------------ 15
第三節 單一細胞實驗------------------------------------------------ 17
第四節 實驗用玻璃微電極之製備--------------------------------- 19
第五節 全細胞膜電位箝定法--------------------------------------- 19
第六節 電生理學研究方法------------------------------------------ 20
第七節 實驗溶液的配製--------------------------------------------- 21
第八節 實驗數據與統計--------------------------------------------- 21
實驗結果
第一節 肺靜脈壁心肌及心室肌組織實驗-------------------------- 23
第二節 單一心臟細胞實驗-------------------------------------------- 27
討論
第一節 乳酸鹽-------------------------------------------------------- 45
第二節 18 Hz自發性高頻波形電位------------------------------ 49
第三節 氫離子的影響----------------------------------------------- 49
結論------------------------------------------------------------------------------- 51
參考文獻------------------------------------------------------------------------- 52
圖目錄
(圖一) 倉鼠心室肌細胞圖--------------------------------------------- 31
(圖二) Acetylcholine對狗左下肺靜脈組織的作用--------------- 32
(圖三) 狗左下肺靜脈心肌組織動作電位-------------------------- 33
(圖四) 乳酸鹽對狗左下肺靜脈心肌組織快速動作電位的作用 34
(圖五) 乳酸鹽對狗左下肺靜脈壁心肌組織高頻不規則節律影響 35
(圖六) 左上與左下肺靜脈壁心肌組織高頻不規則節律比較-- 36
(圖七) 乳酸鹽對倉鼠心室乳突肌組織的影響---------------------- 37
(圖八) 乳酸鹽和乳酸對人類心室肌組織的影響------------------ 38
(圖九) 乳酸鹽對狗左下肺靜脈壁心肌細胞不同時間的影響-- 39
(圖十) 乳酸鹽對倉鼠心室肌細胞不同時間的影響---------------- 40
(圖十一) 乳酸鹽對倉鼠心室肌細胞transient inward current的影響 41
(圖十二) 乳酸鹽對倉鼠心室肌細胞不同去極化電位的影響------ 42
(圖十三) IK電流統計圖---------------------------------------------------- 43
(圖十四) 乳酸鹽對倉鼠心室肌細胞IK1電流的影響---------------- 44

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