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研究生:林麗娟
研究生(外文):Linda L.C. Lin
論文名稱:肌力和耐力性運動與身體活動程度對鈣離子調節激素及骨骼指標之影響
論文名稱(外文):The Effects of strength and endurance exercise on calcium-regulating hormones and bone markers between different levels of physical activity
指導教授:謝伸裕謝伸裕引用關係
指導教授(外文):Sandy Hsieh
學位類別:博士
校院名稱:國立臺灣師範大學
系所名稱:體育研究所
學門:教育學門
學類:專業科目教育學類
論文種類:學術論文
論文出版年:2002
畢業學年度:90
語文別:中文
論文頁數:112
中文關鍵詞:肌力性運動耐力性運動骨骼密度副甲狀腺素降鈣激素
外文關鍵詞:strength exerciseendurance exercisebone mineral densityparathyroid hormonecalcitonin
相關次數:
  • 被引用被引用:6
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  • 下載下載:196
  • 收藏至我的研究室書目清單書目收藏:3
身體活動(physical activity)對身體骨質保存的影響在機械性、物理性機制方面有相當大的貢獻,並可以預防骨質疏鬆症(osteoporosis)。人體中鈣質(Ca2+)為不可或缺的營養素,而人體內調節體內Ca2+濃度的激素,可維持體內Ca2+的恆定,包括副甲狀腺素(parathyroid hormone,PTH)和降血鈣激素(calcitonin,CT)。副甲狀線素使血液中Ca2+濃度升高,而降血鈣激素則使血鈣濃度下降;這二種激素主要作用在調控血液中游離鈣(free ionized calcium)的平衡。本研究目的在探討(1)不同身體活動對骨質密度的影響,(2)不同身體活動者從事急性高阻力的肌力運動和最大耐力運動時對人體血液酸鹼值、血鈣、血漿中游離鈣、副甲狀腺素和降鈣激素的影響。十九名受試者,其中九位為高身體活動組(實驗組),平均訓練年資為 5.93.4年,並維持每週三次以上的跑步訓練。另十名為為低身體活動量組(控制組),在一年內無規律運動習慣。本研究的受試者,分別接受耐力性與肌力性二種不同運動方式後,測量依變項的變化,並以二因子共變數分析(two-way ANCOVA)比較肌力性(離心收縮)和耐力性運動(最大峰值耗氧量)前後對不同身體活動者各依變項(副甲狀腺素、降鈣激素、游離鈣、血鈣濃度和血液pH值)的影響。結果如下:(1)長時間規律且較高的身體活動有助於增加心肺功能與肌肉力量。(2)持續長時間需要負載身體重量的運動有助於骨質的維持與增加。(3)平時活動量較低者,在從事運動時越偏向無氧性的運動(肌力性運動),對於血液中鈣離子增加的刺激越明顯。(4)不同運動型態與不同身體活動量對身體調節激素並無顯著的作用。(5)身體活動量的高低是影響骨質密度重要的因素,高強度肌力性運動對身體血清游離鈣、血液酸鹼度的刺激對於骨質密度的促進有加成的效果。結論:維持規律的高身體活動量有助於提高骨質密度。而肌力性運動對於身體骨質保存除物理性的機制外,肌力運動時血清游離鈣、血液酸鹼度的生化改變對於骨質保存亦有正面的影響。
Physical activity has been shown to maintain bone mineral density (BMD) through the effects of mechanical loading on bone metabolism. However, the effects of exercise on the calcium-regulating hormones and other metabolic variables are not known. The purpose of this study was to compare the effects of strength and endurance exercise on blood pH, total serum calcium, ionized calcium, parathyroid hormone (PTH) and calcitonin (CT) between males of different physical activity. Experimental group consisted of 9 very active males (runners) and the control group consisted of 10 males with no regular exercise within a year. Subjects were asked to perform both strength (eccentric action) and endurance exercises (VO2 peak). The blood pH, total serum calcium, ionized calcium, PTH and CT were measured before and after exercise. A two-way ANCOVA was used for data analysis. The results were as follow:(1)High physical activity with regular exercise can increase cardiovascular function and muscle strength.(2)Exercise with weights helps to maintain and increase bone density.(3)When low level of physical activity male did anaerobic exercise, the free ionized calcium will increase significantly (p<.o5).(4)Mode and intensity of physical activities have no significant effect on body’s regulating hormones.(5)Physical activity level is the major factor on bone density. High level of physical activity plus strength exercise can have additive effect on bone density. Conclusions: Regular high intensity exercise will help increase bone density. Strength exercise can maintain bone density not only through mechanical loading, but also through biochemical changes in free ionized calcium, blood pH which can positively affect bone density.
前序部份
中文摘要………………………………………………….Ⅰ
目次……………………………………………………….Ⅱ
表次……………………………………………………….Ⅳ
圖次……………………………………………………….Ⅴ
本文部份
第壹章 緒論
一、問題背景…………………………………………………….01
二、研究目的…………………………………………………….02
三、研究假設…………………………………………………….02
四、研究限制…………………………………………………….02
五、名詞操作性定義…………………………………………….03
六、研究的重要性……………………………………………….03
第貳章 相關文獻探討
一、前言………………………………………………………….05
二、鈣離子的生理作用………………………………………….05
三、鈣離子的儲存與代謝……………………………………….05
四、調節鈣離子恆定的激素與機轉…………………………….07
五、運動對調節鈣離子激素的影響…………………………….10
六、本章總結…………………………………………………….14
第參章 研究方法與步驟
一、受試對象…………………………………………………….16
二、先前研究…………………………………………………….17
三、實驗設計…………………………………………………….17
四、實驗時間…………………………………………………….18
五、實驗地點…………………………………………………….18
六、實驗步驟與儀器…………………………………………….18
五、資料處理…………………………………………………….29
第肆章 結果
一、 受試者基本資料……………………………………………30
二、 血液基本參數的變化………………………………………31
三、 骨骼生化指標的變化………………………………………38
四、 調節鈣離子激素的變化……………………………………42
第伍章 討論與結論
一、 受試者基本資料……………………………………………50
二、 血液基本參數值的變化……………………………………53
三、 骨質生化指標與調節鈣離子激素的適應…………………55
四、 相關因子的預測……………………………………………64
五、 討論與建議…………………………………………………65
引用文獻
一、中文部分……………………………………………………67
二、英文部份……………………………………………………68
附錄一、受試者須知及參與同意書……………………………76
附錄二、身體狀況與活動情形調查表…………………………77
附錄三、受試者同意書…………………………………………78
附錄四、骨質密度測量表………………………………………79
附錄五、副甲狀腺素與降鈣激素測量步驟……………………80
附錄六、受試者基本資料測量結果………………………….…83
附錄七、統計結果分析表………………………………………96
附錄八、順向選擇法逐步迴歸分析結果………………………108
引用文獻
一、 中文部分
方進隆。(民82)。健康體能的理論與實際。台北:漢文書局。
王正宏。(民83)。血液學。台北:藝軒圖書出版社。
王學中。(民85)。不同年齡層慢跑者與無規律運動者體適能之比較研究。未出版碩士論文,國立台灣師範大學體育研究所,台北市。
何敏夫。(89)。臨床化學(第三版)。台北:合記圖書出版社。
宋成忠、趙樹清譯。(1989)。從運動生化到運動處方。北京:北京體育學院出版社。
林正常。(民84)。運動生理學實驗指引。台北:師大書苑。
林正常。(民86)。運動生理學。台北:師大書苑。
林清山。(民81)。心理與教育統計學。台北:東華書局。
林麗娟。(民83)。不同比例之等速離心和向心聯合收縮訓練對肱二肌和肱三頭肌肌力之影響。未出版碩士論文,國立台灣師範大學體育研究所,台北市。
陳明豐。(民81)。冠狀動脈與心臟病。台北:健康世界雜誌社。
陳順宇、鄭碧娥。(民85)。迴歸分析。台北:華泰書局總經銷。
黃伯超、游素玲。(民79)。營養學精要(八版),台北:健康文化事業股份有限公司。
黃文俊。(民88)。國小五年級男童通學方式與身體活動在健康體適能之影響分析。未出版碩士論文,國立台灣師範大學體育研究所,台北市。
張瑞泰。(民90)。規律慢跑和桌球運動對中、老年人骨密度及生理特質的追蹤研究。中華民國體育學會九十年會員大會學術論文發表大會手冊。
馮煒權、翁慶章。(1990)。血乳酸與運動訓練-應用手冊。北京:人民體育出版社。
楊榮森總編譯。(民86)。骨質疏鬆症-病因,診斷和治療。台北市:合記圖書出版社。
謝伸裕。(民85)。基礎運動生物化學。台北市:力大圖書公司。
二、英文部份
Al-Hazzaa, H. M., & Sulaiman, M. A. (1993). Maximal oxygen uptake and daily physical activity in 7-12 years old boys. Pediatric Exercise Science, 5 , 357-366.
Albert, M.(1991). Eccentric muscle training in sports and orthopaedics. New York: Churchill Livingston Inc.
Aloia, J. F., Rasulo, P., Deftos, L. J., Vaswani, A., & Yeh, J. K. (1985). Exercise-induced hypocalcaemia and the calciotropic hormones. Journal of Laboratory and Clinical Medicine, 106 , 229-32.
Austin, L. A., & Health, H. H. (1981). Calciton: physiology and pathophysiology. New England Journal of Medicine, 304, 269-278.
Bailey, D. A., Faulkner, R. A., & Mckay, H. A. (1996). Growth, physical activity, and bone mineral acquisition. Exercise and Sport Sciences Reviews, 24: 233-266.
Brahm, H., Piehl-Aulin, K., & Ljunghall, S. (1997). Bone metabolism during exercise and recovery: the influence of plasma volume and physical fitness. Calcified Tissue International, 61(3), 192-8.
Brahm, H., Mallmin, H., Michaelsson, K., Strom, H., & Ljunghall, S. (1998). Relationships between bone mass measurements and lifetime physical activity in a Swedish population. Calcified Tissue International, 62(5), 400-12.
Brown, E. M.(1982). PTH secretion in vivo and in vitro regulation by calcium and other secretagogues. Mineral and Electrolyte Metabolism, 8, 130-7.
Brounds, F.(1995). Nutritional needs of athletes. New York: John Wiley & Sons, Inc.
Burdett, R., & Swearingen, J.(1987). Reliability of isokinetic muscle endurance tests. Journal of Orthopaedic Sports and Physical Therapy, 8, 484-488.
Clarke, D. H., Hunt, M. Q., & Dotson, C. O. (1992). Muscular strength and endurance as a function of age and activity level. Research Quarterly, 63(3), 302-310.
Collins, M. A., Cureton, K. J., Hill, D.W., & Ray, C. A. (1989). Relation of plasma volume change to intensity of weight lifting. Medicine & Science in Sports & Exercise, 21, 178-185.
Cunningham, J., Segre, G. V., Slatopolsky, E., & Avioli, L. V.(1985). Effect of heavy exercise on mineral metabolism and calcium regulating hormones in humans. Calcified Tissue International, 37, 598-601.
Dalen, N., & Olsson, K. E. (1974). Bone mineral cent and physical activity. Acta Orthopaedica Scandinavia , 45, 170-4.
Drinkwater, B. L. (1994). Does physical activity play a role in preventing osteoporosis? Research Quarterly for Exercise and Sport, 56, 197-206.
El-Sayed, M. S. (1996). Effects of exercise on blood coagulation, fibrinolysis and platelet aggregation. Sports Medicine, 22(5), 282-98.
Ganong, W. F.(1992). Review of medical physiology(16th ed).Connecticut: Appleton & Lange.
Garcia-Palmieri, M. R., Costas, R., & Cruz-Vidal, M. (1982). Increased physical activity: A protective factor against heart attack in Puerto Rico. American Journal of Cardiology, 50, 749-755.
Grimston, S. K., Tanguay, K. E., Gundberg, C. M., & Hanley, D. A.(1993). The calciotropic hormone response to changes in serum calcium during exercise in female long distance runners. Journal of Clinical Endocrinology and Metabolism, 76, 867-72.
Halioua, L., & Anderson, J. J. B. (1989). Lifetime calcium intake and physical activity habits: independent and combined effects on the radial bone of healthy premenopausal Caucasian women. American Journal of Clinical Nutrition, 49, 534-541.
Henderson, S. A., Graham, H. K., Mollan, R. A. B., Riddoch, C., Sheridan, B., & Johnston, H. (1989). Calcium homeostasis and exercise. International Orthopedics, 13, 69-73.
Holtrop, M. E. Raisz, L. G. (1979). Comparison of the effects of 1,25-dihyfroxycalciferol, prostaglandin E2. and osteoclast activating factor with parathyroid hormone on the ultrastructure of osteoclasts in cultured long bones of fetal rats. Calcified Tissue International, 29, 201-205.
Iacono, A., & Irace, L.(1996). Cardiovascular response to physical exercise. Cardiologia, 41(3), 241-50.
Jackson, J. A., & Kleerekoper, M. (1990). Osteoporosis in men: diagnosis, pathophyiology and preventation. Medicine, 69, 137-52.
Joborn, H., Bergstrom, R., Rastad, J., Wide, L. Akerstrom, G., & Ljunghall, S.(1988). Effects of propranolol and verapamil on plasma ionized calcium and parathyroid hormone in shortterm intense isokinetic leg exercise. Clinical Physiology,8,1-7.
Klausen, T., Breum, L. S.,*Rensen, H. A., Schifter, S., & Sonne, B.(1993). Plasma levels of parathyroid hormone, vitamin D, calcitonin, and calcium in association with endurance exercise. Calcified Tissue International, 52, 205-8.
Kream, B. E., Rowe, D. W., Gworek, S. C. & Raisz, L. G. (1980). Parathyroid hormone alter collage synthesis and procollagen mRNA levels in fetal rat calvaria. Proceedings of the National Academy of Science, 77, 5654-5658.
Kristoffersson, A., Hultdin, J., Thorsen, K., & Lorentzon, R.(1995). Effects of short-term maximal work on plasma calcium, parathyroid hormone, osteocalcin and biochemical markers of collagen metabolism. International Journal of Sports Medicine, 16(3), 145-9.
Maclntyre, I., Kehely, A., Zaidi, M., & Seth, R. (1990). Biological activity of calcitonin and its assessment. Experimental Gerontology, 25, 331-338.
Laforest, S., St-Pierre, M. M., Cyr, J., & Gayton, D. (1990). Effects of age and regular exercise on muscle strength and endurance. European Journal Applied Physiology, 60, 104-111.
Miller, S.C. (1978). Rapid activation of the medullary bone osteoclast cell surface by parathyroid hormone. Journal of Cell Biology, 76, 615-618.
Morris, F. L., Naughton, G. A., Gibbs, J. L., Carlson, J. S., & Wark, J. D. (1997). Prospective ten-month exercise interventioning premenarcheal Girls: positive effects on bone and lean mass. Journal of Bone & Mineral Research, 12(9), 1453-62.
Nishiyama, S., Tomoeda, S., Ohta, T., & Higuchi, A. (1988). Mathsuda I. Differences in basal and postexercise osteoclacin levels in athletic and nonathletic humans. Clacified Tissue International, 43, 150-4.
Nielsen, S. P., Christiansen, T. F., Hartling, O., & Trap-Jensen, J.(1977). Increase in serum ionized calcium during exercise. Clinical Science & Molecular Medicine, 53(6), 579-86.
Nielsen, H. K., Laurberg, P., Brixen, K. & Mosekilde, L.(1991). Relations between diurnal variations in serum osteocalcin, cortisol, parathyroid hormone and ionized calcium in normal individuals. Acta Endocrinologica, 124, 391-8.
O’Neill, M. E., Wilkison, M., Robinson, B. G., McDowall, D. B., Cooper, K. A., & Mihailidou, A. S.(1990).The effect of exercise on circulating immunoreactive calcitonin in men. Hormone and Metabolic Research, 22(10), 546-50.
Parisien, M., Silverberg, S. J., Shane, E., Dempster , D. W., & Bilezikian, J. P. (1990). Bone disease in primary hyperparathyroidism, Endocrinology and Metabolism Clinics of North American, 19, 19-34.
Pazzaglia, E., Zatti, G., Nucci, A. D., & Coci, A. (1993). Inhibitory effect of salmon calcitonin on bone resporption: morphological study of thetibial growth plate in rats. Calcified Tissue International, 52, 125-129.
Pocock, N. A., Eisman, J. A., Hoper, J. L., Yeates, M. G., Sambrook, P. N., & Eberl, S. (1987). Genetics determinants of bone mass in adults: a twin study. Journal of Clinical Nutrition, 80, 706-710.
Pors-Nielsen, S., Falch-Christiansen, T., Hartling, O., & TrapJensen, J. (1977). Increase in serum ionized calcium during exercise. Clinics Science and Medicine, 53, 579-86.
Porter, R.. W., Adams, M. A., & Hutton, W. C. (1989). Physical activity and the strength of the lumbar spine. Spine, 14(2), 201-3.
Prockop, D. J., Kivirkko, K. I., Tuderman, L., & Guzman, N. A.(1979). The biosynthesis of collagen and its disorders. New England Journal of Medicine, 301, 13-23.
Raisz, L. G. (1963). Stimulation of bone resorption by parathyroid hormone in tissue culture. Nature,197, 1015-1016.
Rantanen, T., Era, P., & Heikkinen, E. (1997). Physical activity and the changes in maximal isometric strength in men and women from the age of 75 to 80 years. Journal of the American Geriatrics Society, 45(12), 1439-45.
Resch, H., Pietschmann, P., & Willvonseder, R. (1989). Estimated long-term effect of calcitonin treatment in acute osteoporotic spine fracture. Calcified Tissue International,45, 209-214.
Riggs, B. L., & Melvin, L. J. (1986). Involutional osteporosis. New England Journal of Medicine, 314, 1676-1684.
Riggs, B. L. (1987). Pathogenesis of osteoporosis. American Journal of Obstetrics and Gynecology, 156, 1342-1346.
Rong, H., Berg, U., Torring, O., Sundberg, C. J., Granberg, B., & Bucht E.(1997). Effect of acute endurance and strength exercise on circulating calcium-regulating hormones and bone markers in young healthy males. Scandinavian Journal of Medicine & Science in Sports, 7(3), 152-9.
Rosenblantt, M., Callahan, E. N., & Mahaffey, J. E. (1977). Parathyroid hormone inhibitors: design, synthesis and biologic evaluation of hormone analogues. Journal of Biological Chemistry, 252, 5847-5851.
Rowell, L. B.(1980).What signals govern the cardiovascular responses to exercise?. Medicine & Science in Sports & Exercise, 12(5), 307-15.
Siscovick, D.S., Weiss, N. S., &Fletcher, R. H.(1984). Habitual vigorous exercise and primary cardiac arrest effect of other risk factor on the relationship. Journal Chronic Disease, 37, 625-631.
Takada, H., Washino, K., Nagashima, M. & Iwata, H. (1998). Response of parathyroid hormone to anaerobic exercise in adolescent female athletes. Acta Paediatrica Japonica, 40(1), 73-7.
Thorsen, K., Kristoffersson, A., Hultdin, J., & Lorentzon, R.(1997). Effects of moderate endurance exercise on calcium, parathyroid hormone, and markers of bone metabolism in young women. Calcified Tissue International,60, 16-20.
Tipton, C. M., Greenleaf, J. E. & Jackson, C. G. R.(1996). Neuroendocrine and immune system responses with spaceflights. Medicine and Science Sports and Exercise, 28(8), 988-998.
Torring, O., Bucht, E., & Sjoberg, H. E. (1985). Plasma calcitonin response to a calcium clamp. Influence of sex and age. Hormone and Metabolic Research, 17, 1536-9.
Viru, A.(1995). Adaptation in Sports Training. Boca Raton, Florida, CRC Press, Inc.
Vora, N. M., Kukreja, S. C., York, P. A., Bowser, E. N., Hargis, G. K., & Williams, G. A.(1983) . Effect of exercise on serum calcium and parathyroid hormone. Journal of Clinical Endocrinology and Metabolism, 57, 1067-9.
Vuori, I. (1969). Exercise and physical health: musculoskeletal hearth and functional capabilities. Research Quarterly for Exercise and Sport, 66, 276-285.
Zerath, E., Holy, X., Douce, P., Guezennec, C. Y., & Chatard, J. C. (1997).Effect of endurance training on postexercise parathyroid hormone levels in elderly men. Medicine & Science in Sports & Exercise, 29(9), 1139-45.
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