羅氏鹽膚木(Rhus semialata var. roxburghii)根部以甲醇萃取三次，用乙酸乙酯與水分配萃取，乙酸乙酯層濃縮後以重力管柱層析粗分，接著利用薄層分析、快速管柱層析、高效能液相層析法及再結晶等方法，分離純化得到四十個化合物。包括18個triterpenoids，5個固醇類，2個木酚素類，2個類黃酮類，9個芳香族類及4個其他類。分別為betulonic acid(LU 1), betulinic acid(LU 2), betulin(LU 3), lantabetulic acid(LU 4), lantabetulal(LU 5*), 3-oxoolean-18-en-28-oic acid(OL 1), 3b-hydroxyolean-18-en-28-oic acid(OL 2), 3-oxo-6b-hydroxyolean-18-en-28-oic acid(OL 3), semimoronic acid(OL 4), 3-O-methyl semimoronic acid (OL 5*), 3-oxo-olean-12-en-28-oic acid(OL 6), oleanolic acid(OL 7), lantanolic acid(OL 8), lantanolal (OL 9*), lantanolol (OL 10*), 3-oxotirucalla-7, 24-dien-21-oic acid (TI 1), dipterocarpol(DA 1), 3b-hydroxy-22,23,24,25,26,27-hexanordammarane-20-one(DA 2), b-sitosterol(ST 1) , stigmast-4-en-3-one(ST 2), stigmast-4-en-3,6-dione(ST 3), stigmastan-3,6-dione(ST 4), stigmast-7-en-3-ol(ST 5), pinoresinol(L 1), 2-oxopinoresinol(L 2), (2S)- 4’, 5, 7-trihydroxyflavanone (F 1), trans-3, 4’, 7-trihydroxyflavanone (F 2), vanillin(A 1), methyl ferulate(A 2), 3,5-dihydroxytoluene(A 3), 4-hydroxy-3,5-dimethoxybenzaldehyde(A 4), 3,5-dihydroxy-4-methoxybenzoic acid(A 5), 2,6-dimethoxy-[1,4]benzoquinone(A 6), 3,4,5-trimethoxybenzyl alcohol(A 7), gallic acid(A 8), ficusol(A 9), 2-hydroxy-6-(pentadec-8 Z-enyl) benzoic acid(OT 1), 5-formylmellein(OT 2), 5-hydroxymethylmellein(OT 3), alkyls caffeate(OT 4). 其中四個新化合物分別為lantabetulal (LU 5*), 3-O-methyl semimoronic acid (OL 5*) , lantanolal (OL 9*), and lantanolol (OL 10*)，其結構經由光譜及化學方法決定。
*：新化合物

Abstract
The roots of Rhus semialata var. roxburghii were extracted with methanol for three times. The extract was concentrated in vacuo to yield a residue which was suspended in H2O, and the suspension was then partitioned with ethyl acetate. The ethyl acetate soluble was chromatographied over silica gel column, thin layer plate, flash column, high performance liquid chromatography and recrystallized to afford forty compounds. They included 18 triterpenoids, 5 steroids, 2 lignans, 2 flavonoid, 9 aromatics and 4 others. These were betulonic acid (LU 1), betulinic acid(LU 2), betulin(LU 3), lantabetulic acid(LU 4), lantabetulal(LU 5*), 3-oxoolean-18-en-28-oic acid(OL 1), 3b-hydroxyolean-18-en-28-oic acid(OL 2), 3-oxo-6b-hydroxyolean-18-en-28-oic acid(OL 3), semimoronic acid(OL 4), 3-O-methyl semimoronic acid (OL 5*), 3-oxo-olean-12-en-28-oic acid(OL 6), oleanolic acid(OL 7), lantanolic acid(OL 8), lantanolal (OL 9*), lantanolol (OL 10*), 3-oxotirucalla-7, 24-dien-21-oic acid (TI 1), dipterocarpol(DA 1), 3b-hydroxy-22,23,24,25,26,27-hexanordammarane-20-one(DA 2), b-sitosterol(ST 1) , stigmast-4-en-3-one(ST 2), stigmast-4-en-3,6-dione(ST 3), stigmastan-3,6-dione(ST 4), stigmast-7-en-3-ol(ST 5), pinoresinol(L 1), 2-oxopinoresinol(L 2), (2S)- 4’, 5, 7-trihydroxyflavanone (F 1), trans-3, 4’, 7-trihydroxyflavanone (F 2), vanillin(A 1), methyl ferulate(A 2), 3,5-dihydroxytoluene(A 3), 4-hydroxy-3,5-dimethoxybenzaldehyde(A 4), 3,5-dihydroxy-4-methoxybenzoic acid(A 5), 2,6-dimethoxy-[1,4]benzoquinone(A 6), 3,4,5-trimethoxybenzyl alcohol(A 7), gallic acid(A 8), ficusol(A 9), 2-hydroxy-6-(pentadec-8 Z-enyl-)benzoic acid(OT 1), 5-formylmellein(OT 2), 5-hydroxymethylmellein(OT 3), alkyls caffeate(OT 4). Among these, four are new compounds, ie lantabetulal (LU 5*), 3-O-methyl semimoronic acid (OL 5*), lantanolal (OL 9*), and lantanolol (OL 10*).their structure were elucidated by spectroscopic and chemical methods.
*：new compound

目 錄
第一章緒論……………………………………. 1
第二章化合物結構解析…………………..14
第三章結果與討論………………………..112
第四章實驗部份…………………………..117
第五章參考文獻……………………………...123

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