跳到主要內容

臺灣博碩士論文加值系統

(3.231.230.177) 您好!臺灣時間:2021/08/04 06:12
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果 :::

詳目顯示

: 
twitterline
研究生:楊馨怡
研究生(外文):Yang Hsin Yi
論文名稱:食道癌病人的憂鬱對疾病預後的影響
論文名稱(外文):The impact of depression on disease prognosis in patient with esophageal cancer
指導教授:陳美伶陳美伶引用關係
指導教授(外文):Chen Mei Ling
學位類別:碩士
校院名稱:長庚大學
系所名稱:護理學研究所
學門:醫藥衛生學門
學類:護理學類
論文種類:學術論文
論文出版年:2003
畢業學年度:91
語文別:中文
論文頁數:194
中文關鍵詞:憂鬱狀態食道癌疾病預後
外文關鍵詞:Depression statusEsophageal cancerDisease prognosis
相關次數:
  • 被引用被引用:15
  • 點閱點閱:445
  • 評分評分:
  • 下載下載:128
  • 收藏至我的研究室書目清單書目收藏:2
本研究採前瞻性研究設計,目的在了解食道癌病人長期憂鬱狀態變化,並探討病人憂鬱狀態對疾病預後的影響。在北部某醫學中心,採方便取樣方式收取119 位食道癌病人參與研究,進行二年追蹤以收集相關資料。所得資料以描述性統計、廣義估計方程式、Kaplan-Meier存活分析、Cox比例危害模式等統計方法進行結果分析。
研究結果顯示:(1)90位病人在追蹤二年間死亡,存活時間中位數為12個月,一年、二年累積存活率各為48.27%、23.45%;(2)89位完成不同療程的食道癌病人,33位病人在追蹤二年間出現腫瘤復發,一年、二年累積無復發存活率各為63.42%、51.57%;(3)在各測量時間點病人不一的情況下,各時間點以老人憂鬱量表與醫院焦慮及憂鬱量表-憂鬱部分測得憂鬱盛行率為15.7∼21.1%、17.4∼41.6%,檢定各時間點病人憂鬱狀態並無不同;(4)預後因子單變量分析發現病人初診斷時體重減輕狀態、初診斷時功能狀態、第六個月功能狀態、第十二個月功能狀態,及以老人憂鬱量表與醫院焦慮及憂鬱量表-憂鬱部分測得第四、第六、第十二個月憂鬱狀態會影響病人存活,而僅老人憂鬱量表測得第六個月憂鬱狀態會影響病人疾病復發情形;(5)多變量模式下,調整其他預後因子後,如果病人存活超過四個月,以GDS或HADS-D確認第四個月為憂鬱病人發生死亡事件的風險是非憂鬱病人的1.7489∼3.3115倍,且達統計顯著(p<.05),如果病人存活超過六個月,以HADS-D確認第六個月為憂鬱病人發生死亡事件的風險是非憂鬱病人的2.7145倍,且達統計顯著(p<.05);(6)如果病人存活超過六個月,GDS確認第六個月為憂鬱病人發生復發事件的風險為非憂鬱病人的2.6044倍。
此研究結果提供臨床護理人員了解食道癌病人憂鬱長期變化及其對疾病預後的影響,建議在護理實務上,應加強評估食道癌病人憂鬱狀態,尤其是診斷後第四個月、第六個月的憂鬱狀態,及時確認出憂鬱病人,給予適切護理措施,藉由改善病人憂鬱,提昇病人存活及無復發存活時間。
關鍵字:憂鬱狀態、食道癌、疾病預後
A prospective study design was used. The purposes of this were to understand the long-term changes of depression status, and examine the impact of depression status on disease prognosis in patient with esophageal cancer. One hundred- nineteen esophageal cancer patients were recruited from a medical center in Northern Taiwan with convenient sampling, then two years follow-up to collect data. Data were analyzed by descriptive statistics, Generalized Estimating Equations, Kaplan-Meier survival analysis, Cox’s proportional hazard model.
The major findings of this study were: (1) Ninety patients were died in two years follow-up time, median survival time was 12 month, 1 and 2 year cumulative survival rate was 48.27% and 23.45%; (2) Among eighty-nine patients finished therapy, thirty-three patients had tumor recurrence in two years follow-up time, 1 and 2 year cumulative non recurrence survival rate was 63.42% and 51.57%; (3) Base on each measure time had different patients, depression in the Geriatric Depression Scale (GDS) prevalence rate was 15.7%-21.1% in each measure time, in the Hospital Anxiety and Depression Scale-Depression( HADS-D) was 17.4%-41.6% in each measure time. Compared with baseline date, the depression status did not change with time; (4) Univariate analysis showed that body weights loss level, functional status of diagnosis, functional status of 6th month, functional status of 12th month, depression status of 4th month, 6th month, 12th month in the GDS and HADS-D was significantly related to survival. Only depression status of 6th month in the GDS was significantly related to tumor recurrence; (5) Multivariate analysis, when other relevant covariates were controlled, if patient can survival 4 month, depression status of 4th month in the GDS and HADS-D was significantly related to survival, the increased risk of death during follow-up for the GDS and HADS-D category of depression, relative hazard ration was 1.7489-3.3115. If patient can survival 6 month, depression status of 6th month in the HADS-D was significantly related to survival, the increased risk of death during follow-up for the HADS-D category of depression, relative hazard ration was 2.7145; (6) if patient can survival 6 month, depression status of 6th month in the GDS was significantly related to tumor recurrence, the increased risk of tumor recurrence during follow-up for the GDS category of depression, relative hazard ration was 2.6044.
The findings of this study can help nurses understand the long-term changes of depression status and it’s impact on disease prognosis in esophageal cancer patients. Suggest nurses should assess depression status in esophageal cancer patients, especially 4th month and 6th month after diagnosis, find the depression patient, appropriate nursing interventions to help them improve patient’s depression status in order to increasing survival time and non recurrence survival time.
Key word: Depression status, Esophageal cancer, Disease prognosis
頁數
指導教授推薦書……………………………………………………
口試委員審定書……………………………………………………
博碩士論文授權書……………….……………………………… iii
致謝…………………………………………………………………iv
中文摘要…………………………………………………………… v
英文摘要…………………………………………………………… vii
目錄………………………………………………………………… ix
圖表目錄…………………………………………………………… xii
附件目錄…………………………………………………………… xv
第一章 緒論…………………………………………………………1
第一節 研究背景與重要性…………………………………… 1
第二節 研究動機……………………………………………… 2
第三節 研究目的……………………………………………… 3
第四節 研究問題……………………………………………… 3
第五節 名詞定義……………………………………………… 4
第二章 文獻查證……………………………………………………5
第一節 食道癌………………………………………………… 5
第二節 影響食道癌預後的因素……………………………… 9
第三節 癌症病人的憂鬱……………………………………… 15
第四節 憂鬱對疾病預後的影響……………………………… 28
第三章 研究方法……………………………………………………36
第一節 研究架構……………………………………………… 36
第二節 研究對象……………………………………………… 38
第三節 資料收集方法………………………………………… 39
第四節 研究工具……………………………………………… 41
第五節 資料分析分法………………………………………… 45
第六節 人權的考量…………………………………………… 46
第四章 研究結果與分析……………………………………………47
第一節 食道癌病人基本資料及疾病狀態………………… 47
第二節 食道癌病人各時間點憂鬱狀態變化情形………… 55
第三節 食道癌病人自診斷到追蹤二年間的存活情形……… 62
第四節 影響食道癌病人二年存活時間預後因子的單變量分析…………………………………………………… 65
第五節 影響食道癌病人二年存活時間預後因子的多變量分析…………………………………………………… 74
第六節 食道癌病人自診斷到追蹤二年間的復發情形…… 83
第七節 影響食道癌病人二年無復發存活時間預後因子的單變量分析……………………………………………… 88
第五章 討論…………………………………………………………94
第一節 食道癌病人各時間點憂鬱狀態變化分析…………… 94
第二節 食道癌病人自診斷到追蹤二年間的存活分析……… 97
第三節 憂鬱對食道癌病人存活的影響……………………… 100
第四節 食道癌病人自診斷到追蹤二年間的復發分析……… 110
第五節 憂鬱對食道癌病人疾病復發的影響………………… 111
第六章 結論與建議…………………………………………………113
第一節 結論…………………………………………………… 113
第二節 研究限制……………………………………………… 115
第三節 建議…………………………………………………… 116
參考資料…………………………………………………………… 118
中文部分……………………………………………………… 118
英文部分……………………………………………………… 119
王仁潔、李湘雄譯(2001).憂鬱症.於黎士鳴校閱,老人與健康(pp.210-232).台北:弘智文化。
王雅容(2002).白血病患者之希望、憂鬱與生活品質之相關性探討.未發表的碩士論文,台北:台北護理學院。
行政院衛生署(2002).資訊走廊-衛生統計資料(線上查詢)。摘自http://www.doh.gov.tw/lane/statist/90/we/come.html/.
行政院衛生署(2002).癌症登記年報(線上查詢)。摘自http://crs.cph.ntu.edu.tw/cr c/annual.html/.
李明濱(1997).醫學的人性面:情緒與疾病.台北:台大醫學院。
季匡華(1995).同時放射化學治療:食道癌患的另一選擇.臨床醫學,35(3),172-175。
林同森、黃敏雄(1992).食道癌.臨床醫學,29(1),31-39。
林玲華(1999).癌病住院病患憂鬱之篩檢.未發表的碩士論文,桃園:長庚大學。
洪莉竹(1996).憂鬱個案及輔導策略之探討.諮商與輔導,(121),13-17。
徐如維、李鶯喬(1996).照會精神醫學常見的問題及處理.臨床醫學,38(4),249-253。
張獻崑(2000).食道癌的診斷及治療現況.內科新知,3(2),58-63。
郭明勳(1993).食道癌的病理研究:預後因子評估.未發表的碩士論文,台北:台灣大學。
黃和美(1984).癌症末期病人心理反應之探討.未發表的碩士論文,台北:國防醫學院。
楊庸一(2000).輕型精神疾病(minor psychiatric disorder)的治療.當代醫學,27(5),392-394。
楊庸一(2000).輕型精神疾病之治療.當代醫學,27(6),476-478。
熊佩韋、許文林(1997).食道癌放射治療現況.國防醫學,24(3),186-190。
蔡琇文(1997).癌症疼痛特質、不確定感與心理困擾之相關性探討.未發表的碩士論文,台北:台北護理學院。
賴裕和、林佳靜、廖媛美、鄭素月、林美良、鄭綺、楊莉娌、魏玲玲、方薇芸(1998).拉克曼內外科護理學(第2版).台北:華杏。
簡明建(1999).憂鬱症的診斷及治療.諮商與輔導,165,8-11。
簡淑慧(2000).癌症病人的護理.於廖張京隸總校訂,最新內外科護理學(pp.165-279).台北:永大。
Adham, M., Baulieux, J., Mornex, F., de la Roche de Bransat, E., Ducerf, C., Souquet, J. C., & Gerard, J. P. (2000). Combined chemotherapy and radiotherapy followed by surgery in the treatment of patients with squamous cell carcinomaof esophagus. Cancer , 89(5), 946-954.
American Psychiatric Association. (1994). Diagnostic and stastistical manual of mental disorder(4th ed). Washington, DC: Auther.
Axon, P. R., Simo, R., Fergie, N., Temple, R. H., & Farrington, W. T. (2000). Carcinoma of the hypopharynx and cervical esophagus in young adults. Annals of Otology, Rhinology & Laryngology, 109(6), 590-593.
Barefoot, J. C., Brummett, B. H., Helms, M. J., Mark, D. B., Siegler, L.C., & Williams, R. B. (2000). Depressive symptoms and survival of patients with coronary artery disease. Psychosomatic Medicine, 62(6), 790-795.
Barsevick, A. M., Sweeney, C., Haney, E., & Chung, E. (2002). A systematic qualitative analysis of psychoeducational interventions for depression in patients with cancer. Oncology Nursing Forum, 29(1), 73-84.
Basso, A. M., Depiante-Depaoli, M., & Molina, V. A. (1992). Chronic variable stress facilitates tumoral growth: Reversal by impramine administration. Life Sciences, 50(23), 1789-1796.
Beckham, E. E., Leber, W. R., Youll, L. K. (1995). The diagnostic classifcation of depression. In Beckham, E. E. & Leber, W. R. (Eds), Handbook of depression(pp.36-60). New York: 72 Spring Street.
Billingsley, K. G., Maynard, C., Schwartz, D. L., & Dominitz, J. A. (2001). The use trimodaliity therapy for the treatment of operable esophageal carcinoma in the veteran population. Cancer, 92(5), 1272-1280.
Blewett, C. J., Miller, J. D., Ramlawi, B., Young, J. E. M., Bennett, W. F., & Urschel, J. D. (2001). Local recurrence after total or subtotal esophagectomy for esophageal cancer. Journal of Experimental & Clinical Cancer Research,20(1), 17-19.
Bogomoletz, W. V., Molas, G., Gayet, B., & Potet, F. (1989). Superficial squamous cell carcinoma of the esophagus. The American Journal of Surgical Pathology, 13(7), 535-546.
Bolt, W. J. (1994). Esophageal cancer trendsand risk factors. Seminars in Oncology, 21(4), 403-410.
Breitbart, W. (1994). Psych-oncology: Depression, anxiety, delirium. Seminars in Oncology, 21(6), 754-769.
Brink, T. L., Yesavage, J. A., Lum, O., Heersema, P. H., Adey, M., & Rose, T. L. (1982). Screening tests for geriatric depression. Clinical Gerontologist, 1, 37-43.
Brücher, B. L. D. M., Stein, H. J., Werner, M., & Siewert, J. R. (2001a). Lymphatic vessel invasion is an independent prognostic factor in patients with a primary resected tumor with esophageal squamous cell carcinoma. Cancer, 92(8), 2228-2233.
Brücher, B. L. D. M., Weber, W., Bauer, M., Fink, U., Avril, N., Stein, H. J., Werner, M., Zimmerman, F., Siewert, J. R., & Schwaiger, M. (2001b). Neoadjuvant therapy of esophageal squamous cell carcinoma: Response evalation by positron emission tomography. Annals of Surgery, 233(3), 300-309.
Buccheri, G. (1998). Depressive reactions to lung cancer are common and often followed by a poor outcome. European Respiratory Journal, 11(1), 173-178.
Büla, C. J., Wietlisbach, V., Burnand, B., & Yersin, B. (2001). Depressive symptoms as a predictor of 6-month outcomes and services utilization in elderly medical inpatients. Archives of Internal Medicine, 161(26), 2609-2615.
Calais, G., Dorval, E., Louisot, P., Bourlier, P., Klein, V., Chapet, S., Reynaud-Bougnoux, A., Huten, N., Calan, L. D., Aget, H., & Floch, O.L. (1997). Radiotherapy with high dose rate brachytherapy boost and concomitant chemotherapy for stages ⅡB andⅢ esophageal carcinoma: Results of a pilot study. International Journal of Radiation Oncology, Biology, Physics, 38(4), 769-775.
Cassileth, B. R., Lusk, E. J., Miller, D. S. Brown, L. L., & Miller, C. (1985). Psychosocial correlates of survival in advanced malignant disease? The New England Journal of Medicine, 312(24), 1551-1555.
Chen, M. L., Chang, H. K., & Yen, C. H. (2000). Anxiety and depression in Taiwanese cancer patients with and without pain. Journal of Advanced Nursing, 32(4), 944-951.
Ciaramella, A. & Poli, P. (2001). Assessment of depression among cancer patient: The role of pain, cancer type and treatment. Psycho-Oncology, 10(2), 156-165.
Clipp, E. C., Hollis, D. R., Cohen, H. J. (2001). Considerations of psychoscial illness phase in cancer survival. Psycho-Oncology, 10(2), 166-178.
Coia, L. R. (1994). Chemoradiation as primary management of esophageal cancer. Seminars in Oncology, 21(4), 483-492.
Cooper, J. S., Guo, M. D., Herskovic, A., Macdonald, J. S., Martenson, J. A., Al-Sarraf, M., Byhardt, R., Russell, A. H., Beitler, J. J., Spencer, S., Asbell, S. O., Graham, M. V., & Leichman, L. L. (1999). Chemoradiotherapy of locally advanced esophageal cancer: Long-term follow up of a prospective randomized trial(RTOG 85-01). Radiation Therapy Oncology Group. The Journal of the American Medical Association, 281(17), 1623-1627.
Covinsky, K. E., Kahana, E., Chin, M. H., Palmer, R. M., Fortinsky, R. H., & Landefeld, C. S. (1999). Depressive symptoms and 3-years mortality in older hospitalized medical patients. Annal of Internal Medicine, 130(7), 563-569.
De-Leeuw, J. R. J., Graeff, A. D., Ros. W. J. G., Hordijk, G. J., Blijham, G. H., & Winnubst, J. A. M. (2000). Negative and positive influences of social support on depression in patients with head and neck cancer: Prospective study. Psycho-Oncology, 9(1), 20-28.
Devine, E. C. & Westlake, S. K. (1995). The effects of psychoeducational care provided to adults with cancer: Meta-analysis of 116 studies. Oncology Nursing Forum, 22(9), 1369-1381.
Dugan, W., McDonald, M. V., Passik, S.D., & Rosenfeld, B. D. (1998). Use of Zung Self-Rating Depression Scale in cancer patients: Feasibility as a screening tool. Psycho-Oncology, 7(6), 489-493.
Dunne, B., Reynolds, J. V., Mulligan, E., Kelly, A., & Griffin, M. (2001). A pathological study of tumour regression in oesophageal adenocarcinoma treated with preoperative chemoradiotherapy. Journal of Clinical Pathology, 54(11), 841-845.
Faller, H., Bülzebruck, H., Drings, P., & Lang, H. (1999). Coping, distress, and survival among patients with lung cancer. Archives of General Psychiatry, 56(8), 756-762.
Fawzy, F. I., Fawzy, N. W., Hyun, C. S., Elashoff, D. G., Fahey, J. L., & Morton, D. L. (1993). Malignant Melanoma effects of an early structured psychiatric intervention, coping, and affective state on recurrence and survival 6 yers later. Archives of General Psychiatry, 50(9), 681-689.
Forastiere, A. A., Orringer, M. B., Perez-Tamayo, C., Urba, S. G., Husted, S., Takasugi, B. J., & Zahurak, M. (1990). Concurrent chemotherapy and radiation therapy followed by transhiatal esophagectomy for local-regional cancer of the esophagus. Journal of Clinical Oncology, 8(1), 119-127.
Goodwin, P. J., Leszcz, M., Ennis, M., Koopmans, J., Vincent, L., Guther, H., Drysdale, E.,Hundleby, M., Chochinov, H. M., Navarro, M., Speca, M., & Hunter, J. (2001). The effect of group psychosocial support on survival in metastatic breast cancer. The New England Journal of Medicine, 345(24), 1719-1726.
Gruzelier, J., Clow, A., Even, P., Lazar, I., & Walker, L. (1998). Mind-body influences on immunity: Lateralized control, stress,individual difference predictors, and prophylaxis. Annals New York Academy of Sciences, 851, 487-494.
Hambraeus, G. M., Mercke, C. E., Willen, R., Ranstam, J., Samuelsson, L., Lamm, I. L., & Landberg T. (1988). Prognostic factor influencing survival in combined radiotherapy and surgery of squamous cell carcinoma of the esophagus with special reference to a histopathologic grading system. Cancer, 62(5), 895-904.
Herrmann, C., Brand-Driehorst, S., Kaminsky, B. Leibing, E., Staats, H., & Rüger, U. (1998). Diagnostic groups and depressed mood as predictors of 22-month mortality medical inpatients. Psychosomatic Medicine, 60(5), 570-577.
Hilakivi-Clarke, L., Rowland, J., Clark, R., & Lippman, M. C. (1993). Psychosocial factors in the development and progression of breast cancer. Breast Cancer Research and Treament, 29(2), 141-160.
Hoeber, L. & Irwin, M. M. (1992). Gastrointestinal tract cancer: Current knowledge, medical treatment, and nursing management. Oncology Nursing Forum, 19(9), 1403-1415.
Holland, J. C., Romano, S. J., Heiligenstein, J. H., Tepner, R. G., & Wilson, M. G. (1998). A controlled trial of fluoxtine and despramine in depressed women with advanced cancer. Psycho-Oncology, 7(4), 291-300.
Hölscher, A. H., Bollschweiler, E., Schneider, P. M., & Siewert, R. (1995). Prognosis of early esophageal cancer comparison between adeno-and squamous cell carcinoma. Cancer, 76(2), 178-186.
Ikeda, G., Isaji, S., Das, B. C., Watanabe, M., & Kawarada, Y. (1999). Prognostic significance of biologic factors in squamous cell carcinoma of the esophagus. Cancer, 86(8), 1396-1405.
Ilson, D. H. & Kelsen, D. P. (1994). Combined modality therapy in the treatment of esophageal cancer, Seminars in Oncology, 21(4), 493-507
Jackson, R. & Baldwin, B. (1993). Detecting depression in elderly medically ill patients: The use of the Geriatric Depression Scale compared with medical and nursing observations. Age and Ageing, 22(5), 349-353.
Jamison, R. N., Burish, T. G., Wallston, K. A. (1987). Psychogenic factors in predicting survival of breast cancer patients. Journal of Clinical Oncology, 5(5), 768-772.
Kato, H., Tachimori, Y., Watanabe, H., & Iizuka, T. (1993). Evaluation of the new (1987) TNM classification for thoracic esophageal tumors. International Journal of Cancer, 53(2), 220-223.
Katz, R., Shaw, B. F., Vallis, T. M., & Kaiser, A. S. (1995). The assessment of severity and symptom patterns in depression. In Beckham, E. E. & Leber, W. R. (Eds), Handbook of depression(pp.61-85). New York: 72 Spring Street.
Kim, J. H., Choi, E. K., Kim, S. B, Park, S. I., Kim, D. K., Song, H. Y., Jung, H. Y., & Min, Y. I. (2001). Preoperative hyperfractionated radiotherapy with concurrent chemotherapy in resectable esophageal cancer. International Journal of Radiation Oncology, Biology, Physics, 50(1), 1-12.
Klimstra, D. S. (1994). Pathologic prognostic factors in esophageal carcinoma. Seminars in Oncology, 21(4), 425-430.
Kurlowicz, L. (1999). The Geriatric Depression Scale. Journal of Gerontological Nursing, 25(7), 8-9.
Lee, H. C. B., Chiu, H. F. K., Kwok, W. Y., Leung, C. M., Kwong, P. K., & Chung, D. W. S. (1993). Chinese elderly and the GDS short form: Apreliminary study. Clinical Gerontologist, 14, 37-42.
Lee, J. M., Wu, M. T., Hsu, H. H., Yang, P. W., Hsu, W. L., Yu, S. L., Chen, J. S., Luh, S. P., Lee, C. J., Chen, C. J., & Lee, Y. C.(2000). The etiology of esophageal cancer in Taiwan. Formosan Journal of Surgery, 33(6), 261-266.
Lesher, E. & Berryhill, J. S. (1994). Validation of the geriatric depression scale- short form among inpatients. Journal of Clinical Psychology, 50(2), 256-260.
Lew, J., Gooding, W. E., Ribeiro, U., Safatle-Ribeiro, A. V., & Posner, M. C. (2001). Long-term survival following induction chemoradiotherapy and esophagectomy for esophageal carcinoma. Archives Surgery, 136(7), 737-742.
Lieberman, M. D., Shriver, C. D., Bleckner, S., Burt, M., & the Thoracic and Gastric and Mixed Tumor Services. (1995). Carcioma of the esophagus prognostic significance of histologic type. The Journal of Thoracic and Cardiovascular Surgery, 109(1), 130-139.
Lovejoy, N. C., Tabor, D., & Deloney, P. (2000). Cancer-related depression: Part Ⅱ-neurologic alterations and evolving approaches to psychopharmacology. Oncology Nursing Forum, 27(5), 795-808.
Lovejoy, N. C., Tabor, D., Matteis, M., & Lillis, P. (2000). Cancer-related depression: Part Ⅰ-neurologic alterations and cognitive-behavioral therapy. Oncology Nursing Forum, 27(4), 667-677.
Machin, D. & Campell, M. J. (1987). Statistical tables for the design of clinical trials. Oxford: Blackwell Scientific Publication.
Maguire, G. P., Lee, E. G., Bevington, D. J., Küchemann, C. S., Crabtree, R. J., & Cornell, C. E. (1978). Psychiatric problems in the first year after mastectomy. British Medical Journal, 1(6118), 963-965.
Maguire, P. (1997). Depression and cancer. In Robertson, M. M. & Katona, C. L. E. (Eds), Deprression and Physical Illness(pp.429-441). New York: John Wiley & Sons.
McDonald, M. V., Passik, S. D., Dugan,W., Rosenfeld, B., Theobald, D., & Edgerton, S. (1999). Nurses’ recognition of depression in their patients with cancer. Oncology Nursing Forum, 26(3), 593-599.
Meara, J., Mitchelmore, E, & Hobson, P. (1999). Use of the GDS-15 geriatric depression scale as a screening instrument for depressive symptomtology in patients with parkinson’s disease and their carers in the community. Age and Ageing, 28(1), 35-38.
Miaskowski, C. & Dibble, S. L. (1995). The problem of pain in outpatients with breast cancer. Oncology Nursing Forum, 22(5), 791-797.
Middelboe, T., Ovesen, L., Mortensen, E. L., & Bech, P. (1994). Depressive symptoms in cancer patients undergoing chemotherapy: A psychometric analysis. Psychotherapy Psychosomatics, 61, 171-177.
Minsky, B. D., Pajak, T. F., Ginsberg, R. J., Pisansky, T. M., Martenson, J., Komaki, R., Okawara, G., Rosenthal, S. A., & Kelsen, D. P. (2002). INT 0123(radiation therapt oncology group 94-05) phaseⅢ trial of combined-modality therapy for esophageal cancer: High-dose versus standard-dose radiation therapy. Journal of Clinical Oncology, 20(5), 1167-1174.
Mock, V., Dow, K. H., Meares, C. J., Grimm, P. M., Dienemann, J. A., Haisfield-Wolfe, M. L., Quitasol, W., Mitchell, S., Chakavarthy, A., & Gage, I. (1997). Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer. Oncology Nursing Forum, 24(6), 991-1000.
Montazeri, A., Jarvandi, S., Haghligat, S., Vahdani, M., Sajadian, A.,Ebrahimi, M. & Haji-Mahmoodi, M. (2001). Anxiety and depression in breast cancer patients before and after participation in a cancer support group. Patient Education and Counseling, 45(2001), 195-198.
Montorio, I. & Izal, M. (1996). The Geriatric Depression Scale: Areview of its development and utility. International Psychogeriatrics, 8(1), 103-112.
Mor, V., Laliberte, L., Morris, J. N., & Wiemann, M. (1984). The Karnofsky Performance Status Scale: A examination of its reliability and validity in a research setting. Cancer, 53(9), 2002-2007.
Mui. A. C. (1996). Geriatric Depression Scale as a community screeninginstrument for elderly chineseimmigrants, International Psychogeriatrics, 8(3), 445-458.
Murberg, T. A., Bru, E., Svebak, S. Tveteras, R., & Aarsland, T. (1999). Depressed mood and subjective health symptoms as predictors of mortality in patients with congestive heart failure: A two-years follow-up study. International Journal of Psychiatry in Medivine, 29(3), 311-326.
Nakadi, I. E., Laethem, J. L.V., Houben, J. J., Gay, F., Closset, J., Houtte, P. V., Danhier, S., Limbosch, J. M., Lambilliotte, J. P., & Gelin, M. (2002). Squamous cell carcinoma of esophagus: Multimodal therapy in locally advanced disease. World Journal of Surgery, 26(1), 72-78.
National Cancer Institute.(1999). Common toxicity criteria, version 2.0. Available http://ctep.cancer.gov/forms/CTCv20 4-30-992.pdf
Nishimura, Y., Suzuki, M., Nakamatsu, K., Kanamori, S., Yagyu, Y., & Shigeoka, H. (2002). Prospective trial of concurrent chemoradiotherapy with protracted infusion of 5-fluorouracil and cisplatin for T4 esophageal cancer with or without fistula. International Journal of Radiation Oncology, Biology, Physics, 53(1), 134-139.
Nordgren, J. C. (1995). Instruments for assessing depression in adults. In Beckham, E. E. & Leber, W. R. (Eds), Handbook of depression(pp.147-199). New York: 72 Spring Street.
Nozoe, T., Kimura, Y., Ishida, M., Saeki, H., Korenaga, D., & Sugimachi, K. (2002). Correlation of pre-operative nutritional condition with post-operative complications in surgical treatment for oesophageal carcinoma. European Journal of Surgical Oncology, 28(4), 396-400.
O’Gorman, P., McMillan, D. C., & McArdle, C. S. (2000). Prognostic factors in advanced gastrointestinal cancer patients with weight loss. Nutrition and Cancer, 37(1), 36-40.
Ohga, T., Kimura, Y., Futatsugi, M., Miyazaki, M., Saeki, H., & Nozoe, T. (2002). Surgical and oncological advances in the treatment of esophageal cancer. Surgery, 131(1), S28-34.
Parle, M., Jones, B., & Maguire, P. (1996). Maladaptive coping and affective disorders among cancer patients. Psychological Medicine, 26(4), 735-744.
Pettingale, K. W., Morris, T., Greer, S., & Haybittle, J. L. (1985). Mental attitudes to cancer: Aadditional prognostic factor. Lancet, 1(8431), 750.
Rozzini, R., Sabatini, T., Frisoni, G. B., Trabucchi, M., & Italy, B. (2002). Depression and major outcomes in older patients with heart failure. Archives of Internal Medicine, 162(3), 362-363.
Rozzini, R., Sabatini, T., Frisoni, G. B., Trabucchi, M., & Italy, B. (2002). Depression symptoms and negative outcomes in older hospitalized patients. Archives of Internal Medicine, 162(8), 948-949.
Sarna, L. (1994). Functional status in women with lung cancer. Cancer Nursing, 17(2), 87-83.
Schulz, R., Beach, S. R., Ives, D. G., Martire, L. M., Ariyo, A. A., & Kop, W. J. (2000). Association between depression and mortality in older adults. Archives of Internal Medicine, 160(12), 1761-1768.
Schwenk, T. L. (1998). Cancer and depression. Oncology, 25(2), 505-513.
Segar, M. L., Katch, V. L., Roth, R. S., Garcia, A. W., Portner, T. I., Glickman, S. G., Haalanger, S., & Wilkins, E. (1998). The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncology Nursing Forum, 25(1), 107-113.
Sellick, S. M. & Crooks, D. L. (1999). Depression and cancer: An appraisal of the literature for prevalence, detection, and practice guideline development for psychological interventions. Psycho-Oncology, 8(4), 315-333.
Servellen, G. V, Sarna, L., Padilla, G., & Brecht, M. L. (1996). Emotional distress in men with life-threatening illness. Intnational Journal of Nursing Studies, 33(5), 551-565.
Sheikh, J. I. & Yesavage, J. A.(1986). Geriatric depression scale. Recent evidence and development of a shorter version. Clinical Gerontologist, 5, 165-173.
Spiegel, D., Bloom, J. R., Kraemer, H. C., & Gottheil, E. (1989). Effect of psychosocial treatment on survival of patients with metastatic breast cancer. Lancet, 2(8668), 888-891.
Stevens, D. E., Merikangas, K. R., & Merikangas, J. R. (1995). Comorbidity of depression and other medical conditions. In Beckham, E. E. & Leber, W. R. (Eds), Handbook of depression(pp.147-199). New York: 72 Spring Street.
Sugimachi, K., Ohno, S., Matsuda, H., Mori, M., Matsuoka, H., & Kuwano, H. (1989). Clinicopathologic study of early stage esophageal carcinoma. Surgery, 105(6), 706-710.
Tachibana, M., Dhar, D. K., Kinugasa, S., Kotoh, T., Shibakita, M., Ohno, S., Masunaga, R., Kubota, H., & Nagasue, N. (2000). Esophageal cancer wth distant lymph node metastasis: Prognostic significance of metastatic lymph node ratio. Journal of Clinical Gastroenterology, 31(4), 318-322.
Tachibana, M., Kinugasa, S., Dhar, D. K., Kotoh, T., Shibakita, M., Ohno, S., Masunaga, R., Kubota, H., Kohno, H., & Nagasue, N. (1999b). Prognostic factors after extended esophagectomy for squamous cellcarcinoma of the thoracic esophagus. Journal of Surgical Oncology - supplement, 72(2), 88-93.
Tachibana, M., Kinugasa, S., Dhar, D. K., Tabara, H., Masunaga, R., Kotoh, T., Kubota, H., & Nagasue, N. (1999a). Prognostic factor in T1 and T2 squamous cell carcinoma of the thoracic esophagus. Archives of Surgery, 134(1), 50-54.
Tasmuth, T., Estlanderb, A. M., & Kalso, E. (1996). Effect of present pain and mood on the memory of past postoperative pain in women treated surgically for breast cancer. Pain, 68(2-3), 343-347.
Theunissen, M. H., Borchard, F., & Poortvliet, D.C. J. (1991). Histopathological evaluation of oesophageal carcinoma: The significance of venous invasion. British Journal of Surgery, 78(8), 930-932.
Tjemsland, L., Søreide, J. A., Matre, R., & Malt, U. F. (1997). Properative psychologicial variables predict immunological status in patients with operable breast cancer. Psycho-Oncology, 6(4), 311-320.
Tross, S., HerndonⅡ, J., Korzun, A., Kornblith, A. B., Cella, D. F., Holland, J. F., Raich, P., Johnson, A., Kiang, D. T., Perloff, M., Norton, L., Wood, W., & Holland, J. C. (1996). Psychological symptoms and disease-free and overall survival in women with stageⅡ brease cancer. Journal of the National Cancer Institute, 88(10), 661-667.
Twillman, R. K. & Manetto, C. (1998). Concurrent psychotherapy and pharmacotherapy in the treatment of depression and anxiety in cancer patients. Psycho-Oncology, 7(4), 285-290.
Walsh, T. N., Noonan, N., Hollywood, D., Kelly, A., Keeling, N., & Hennessy, T. P. J. (1996). A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. The New England Journal of Medicine, 335(7), 462-467.
Watson, M., Haviland, J. S., Greer, S., Davidson, J., & Bliss, J. M. (1999). Influence of psychological response on survival in breast cancer: A population-based chort study. Lancet, 354(9187), 1331-1336.
Whooley, M. A. & Browner, W. S. (1998). Association between depressive symptoms and mortality in older women. Archives of Internal Medicine, 158(19), 2129-2135.
Wilkinson, G., Moore, B., & Moore, P. (1999). Treating people with depression: A practical guide for primary care. Oxan: Radcliffe Medical Press.
Wulsin, L. R. (2000). Does depression kill? Archives of Internal Medicine, 160(12), 1731-1732.
Yamamoto, H., Adachi, Y., Itoh, F., Iku, S., Matsuno, K., Kusano, M., Arimura, Y., Endo, T., Hinoda, Y., Hosokawa, M., & Imai, K. (1999). Association of matrilysin expression with recurrence and poor prognosis in human esophageal squqmous cell carcinoma. Journal of Cancer Research, 59(4), 3313-3316.
Yamamoto, H., Itoh, F., Iku, S., Hosokawa, M., & Imai, K. (2001). Expression of the γ2 chain of laminin-5 at the invasive front is associated with recurrence and poor prognosis in human esophageal squqmous cell carcinoma. Clinical Cancer Research, 7(4), 896-900.
Yates, J. W., Chalmer, B., & McKegney, F. P. (1980). Evaluation of patients with advanced cancer using the Karnofsky Performance Status. Cancer, 45(8), 2220-2224.
Yeh, T. L., Liao, I. C., Yang, Y. K., Ko, H. C., Chang, C. J., & Lu, F. H. (1995). Geriatric depression scale(Taiwanese and Mandarin translations). Clinical Gerontologist, 15, 58-60.
Yesavage, J. A., Brink, T. L., Rose, T. L., Lum, O., Huang, V. S. (1983). Development and validation of a geriatric depression screening scale: A preliminary report. Journal of Psychiatric Research, 17, 37-39.
Zimmerman, L., Story, K. T., Gaston-Johansson, F., & Rowles, J. R. (1996). Psychologicl variables and cancer pain. Cancer Nursing, 19(1), 44-53.
QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top