臺灣博碩士論文加值系統

本研究以原水母瓣的設計概念為基礎，提出一款外形較符合流體力學原理的修正型水母瓣(Modified Jellyfish Valve)。原水母瓣中央血流速度快，因此我們減少該區堿的輪輻數目，並將原水母瓣的梯型輪幅外形修改為較流線型的橢圓型，以降低瓣膜後方分離泡及紊流小渦產生的機會。為避免薄膜因輪幅減少而發生脫垂(Prolapse)，則在辦膜出口處增加一竇腔(Sinus)設計以增加薄膜支撐面積並協助薄膜提早關閉。在定常流場(Steady Flow)實驗中發現修正型水母瓣的有效孔徑面積(EOA)大於原水母瓣；分別為2.564 及1.612 (流量24l/min)。為了觀察心瓣在真實人體使用時的性能參數；故設計一脈動複製器(Pulse Duplicator)來產生與人體真實流場相仿的脈動流場，並比較機械瓣(Metronic Hall Valve)、修正型水母瓣與原水母瓣在脈動流場下之性能。我們發現在低流量(< 5L/min)下，機械瓣的EOA與迴流量均比兩款水母瓣大，而修正型水母瓣的有效孔徑面積較原水母瓣略大，約增加10%~80%，但迴流量則為原水母瓣的1.5~4倍。

A modified Jellyfish valve was designed based on the original Jellyfish valve and fluid dynamic consideration. The new design reduced the number of spokes positional in the central flow region and adopted elliptic cross sections to make the spokes more streamline shaped. In order not to make the valve membrane prolapse during the diastole phase, a sinus was added at the outlet of the Jellyfish valve. This idea not only increases the supporting area of the membrane, but helps the membrane to close earlier so that the regurgitation is minimized. Experiments were conducted to evaluate the homodynamic performances of the two Jellyfish valves. In the steady-state flow test, the Effective Orifice Area (EOA) has been shown almost doubled with the modified design for flowrate up to 24 L/min. Unsteady experiment using pulse duplicator were also performed for Medtronic Hall, Jellyfish and modified Jellyfish valves. It was found that , for flowrate less than 5 L/min , Medtronic Hall Valve has larger EOA and regurgitation flow as compared to the two Jellyfish valves . Moreover, in this low flowrate range, the modified Jellyfish valve enjoys larger EOA but comparable regurgitation flow as compared to those of the original design. As a result, it is justified in the present research that the strategies proposed to modify the Jellyfish valve are feasible and effective.

中文摘要…………………………………………………………………i
英文摘要…………………………………………………………………ii
誌謝………………………………………………………………………iii
目錄………………………………………………………………………iv
表目錄……………………………………………………………………vii
圖目錄……………………………………………………………………viii
符號說明…………………………………………………………………x
第一章 緒論……………………………………………………………1
1-1 前言………………………………………………………………1
1-2 人工心瓣簡介……………………………………………………2
1-3 水母瓣簡介………………………………………………………3
1-4 研究目的與方法…………………………………………………5
第二章 設計公式介紹…………………………………………………7
2-1 有效孔徑面積………………………………………………………7
2-2 順容器………………………………………………………………11
2-3 阻抗模擬裝置………………………………………………………12
2-4 脈動流場的資料分析………………………………………………14
第三章 修正型水母瓣的設計概念…………………………………17
3-1 輪幅根數與支撐面積……………………………………………17
3-2 輪幅外形與流場…………………………………………………18
3-3 薄膜厚度…………………………………………………………19
3-4 水母瓣製造過程…………………………………………………20
第四章 實驗儀器設備………………………………………………21
4-1 定常流實驗設備…………………………………………………21
4-1-1 整流段…………………………………………………………21
4-1-2 測試段…………………………………………………………22
4-1-3 人工心瓣………………………………………………………22
4-1-4 浮子流量計……………………………………………………23
4-1-5 壓差計…………………………………………………………23
4-1-6 資料擷取系統……………………………………………………23
4-1-7 實驗量測步驟與方法……………………………………………24
4-2 脈動複製器…………………………………………………………24
4-2-1 壓縮系統…………………………………………………………24
4-2-2 測試段……………………………………………………………25
4-2-3 壓力轉換計………………………………………………………26
4-2-4 超音波流量計……………………………………………………26
4-2-5 實驗量測步驟與方法……………………………………………26
第五章 實驗數據與討論………………………………………………28
5-1 測試瓣膜在定常流場下的特性曲線………………………………28
5-2 測試瓣膜在脈動流場下的數據分析………………………………29
第六章 結論與未來發展………………………………………………31
6-1結論 …………………………………………………………………31
6-1未來工作 ……………………………………………………………32
參考文獻…………………………………………………………………33
表…………………………………………………………………………37
圖………………………………………………………………………44
自述……………………………………………………………………68

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