臺灣博碩士論文加值系統

血糖感測器主要應用在糖尿病患者的血糖控制方面。糖尿病是目前社會上相當普遍的文明病，無法完全治癒只能加以控制，排名我國十大死因中的第5名，每年耗費大量醫療費用，降低經濟生產力。若能有效控制血糖與糖化血色素的濃度，糖尿病患者的併發症比例將可以降低50%至75%。而控制血糖的關鍵，就在於適時、密集而且準確地測量血糖，血糖計可能是繼血壓計與體溫計之後，最重要的居家醫療儀器。
吾人實驗室已利用微機電製程技術研發出可以同時檢測血液中不同成分含量的微型生醫檢測晶片，為了配合該血糖感測器的後續量測，並進一步達到感測器與放大電路結合，完成單一晶片系統製作出微血糖計的目標，本文設計微電流放大器，實際送國家晶片設計中心下線，使用TSMC 0.35μm 1p4m製程完成積體電路，晶片成品面積1.460mmX 1.761mm，操作電壓3.1V，負偏壓1.45V，可作用的範圍在輸入電流0~400nA之間，配合血糖感測器，換算出最高可量測的血糖濃度為73.8mM。解析度到0.538mM，可量測濃度範圍在0.538mM~73.8 mM。驗證在電路模擬與實際成品之間，誤差在能接受的程度，該晶片的效能可與血糖感測器搭配使用。

摘要.........................................................Ⅰ
誌謝.........................................................II
目錄........................................................III
圖目錄.......................................................VI
表目錄........................................................X
第一章 序論...................................................1
1.1 前言................................................2
1.3 文獻回顧............................................3
第二章 放大器原理............................................13
2.1 功率放大器.........................................13
2.2 放大器的分類.......................................13
2.2.1 A類功率放大器................................13
2.2.2 B類功率放大器................................15
2.2.3 AB類功率放大器...............................16
2.2.4 C類功率放大器................................18
2.2.5 D類功率放大器................................19
2.2.6 E類功率放大器................................20
2.2.7 F類功率放大器................................20
2.2.8 總結.........................................21
第三章 電流放大器設計........................................23
3.1 電流放大器設計.....................................23
3.2 電路設計考量.......................................25
3.3 電路設計一.........................................26
3.3.1 電路架構.....................................26
3.3.2 特性模擬.....................................28
3.3.3 佈局圖.......................................33
3.4 電路設計二.........................................34
3.4.1 電路架構.....................................34
3.4.2 特性模擬.....................................36
3.4.3 佈局圖.......................................39
3.5 電路設計三.........................................40
3.5.1 電路架構.....................................40
3.5.2 特性模擬.....................................42
3.5.3 佈局圖.......................................44
3.6 晶片完整佈局.......................................45
第四章 量測系統..............................................47
4. 1 微血糖感測器.....................................47
4. 2 量測架構.........................................52
第五章 晶片量測結果..........................................57
5. 1 晶片量測.........................................57
5. 2 設計一量測結果...................................57
5. 3 設計二量測結果...................................62
5. 4 設計三量測結果...................................65
第六章 結論..................................................68
5. 1 結論.............................................68
參考文獻.....................................................69

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