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研究生:陳奕安
研究生(外文):Yi-an Chen
論文名稱:心血管支架設計與分析之研究
論文名稱(外文):A Study on the Design and Analysis of Coronary Stents
指導教授:蔡穎堅
指導教授(外文):Ying-Chien, Tsai
學位類別:碩士
校院名稱:國立中山大學
系所名稱:機械與機電工程學系研究所
學門:工程學門
學類:機械工程學類
論文種類:學術論文
論文出版年:2004
畢業學年度:92
語文別:中文
論文頁數:54
中文關鍵詞:血管支架有限元素分析機構
外文關鍵詞:MechanismStentAnsys
相關次數:
  • 被引用被引用:12
  • 點閱點閱:466
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  • 下載下載:138
  • 收藏至我的研究室書目清單書目收藏:0
心血管支架是一種薄壁管狀裝置,利用其可擴張的特性,藉以支撐狹窄的部位來治療冠狀動脈的狹窄。本研究以機構設計的方法改良現有之血管支架,首先將薄壁管狀的支架視為一平面構造,並進一步將其視為撓性機構。血管支架有幾個設計重點,首先要能夠有足夠的強度來支撐血管壁,同時還要保有足夠的彈性,並且支架擴張時是否均勻以及會不會產生長度的改變也是影響支架置放的重要因素。本研究利用3D繪圖軟體Pro/Engineer以及有限元素分析軟體ANSYS建構並且分析所設計之血管支架,藉由分析的結果發現缺點並加以改良,設計出新型的血管支架構造。
本研究的新型設計在擴張的過程中,其在長軸方向不會有長度變化,克服血管支架在擴張時會產生的軸向縮短問題,使支架在置放時能夠更精確更可靠。
Coronary stents are generally tubular-shaped expandable devices which function to hold open a segment of a blood vessel. They are particularly suitable for use to support and hold back a dissected lumen. This study aims to improve the existing designs of coronary stents through geometry design. This study focuses on the flexible mechanism and planar strut of a thin wall tubular stent to design a new type of coronary stent. A good coronary stent has to meet various requirements. First of all, a coronary stent has to be strong enough to support the wall of the blood vessel. Secondly, it has to be elastic enough. Thirdly, the longitudinal length shorten with dilatation should be as less as possible, otherwise it is difficult to implant precisely. Computer aided design software Pro Engineer is used to build the solid model and then CAE software ANSYS is used to analyze the dilatation of the new stent. After several modifications, a new type of stent with no longitudinal shortening is designed.
謝誌
目錄
圖目錄
表目錄
表目錄
摘要
英文摘要
第一章 緒論
1.1 研究背景與研究動機
1.2 文獻回顧
1.3 研究目標與論文結構
第二章 血管支架的介紹
2.1 血管支架手術介紹
2.2 血管支架的歷史
2.3 血管支架的分類以及加工介紹
第三章 心血管支架設計之方法
3.1 研究方法與步驟
3.2 心血管支架之構造設計
第四章 心血管支架之模擬分析
4.1 商用支架實體特徵之建構與分析
4.2 本研究設計之模擬與分析
第五章 結論與建議
研究成果
本研究設計之加工建議
參考文獻
附錄 血管支架的基本性質
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[2] Cardon, A., Kerdiles, Y., Boliveau, M., Ansel, D., and Debuigne, J., 1995, “Stent for Transluminal Implantation,” US Patent 5,383,892.

[3] Rundnick, J. J. and Wiktor, D. M., 1996, “High Strength and High Density Intraluminal Wire Stent,” US Patent 5,575,816.

[4] Robert, E. F., David R. F., and Tim A. F., 1997, “Longitudinally Elongating Balloon Expandable Stent,” US Patent 5,695,516.

[5] Balcon, R., Beyar, R., Chierchia, S., Sheerder, I., Hugenholtz, P. G., Kiemeneij, F., Meier, B., Meyer, J., Monassier, J. P., and Wijns, W., 1997, “Recommendations on Stent Manufacture, Implantation and Utilization,” European Heart Journal, Vol.18, pp. 1536–1547.

[6] Dumoulin, C. and Colchelin, B., 2000, “Mechanical Behavior Modeling of Balloon-Expandable Stents,” Journal of Biomechanics, Vol. 33, pp 1461-1470.

[7] Etave, F., Finet, G., Boivin, M., Boyer, J. C., Riouful, G., and Thollet, G., 2001, “Mechanical Properties of Coronary Stents Determined by Using Finite Element Analysis,” Journal of Biomechanics, Vol. 34, pp 1065-1075.

[8] Migliavacca, F., Petrini, L., Colombo, M., Auricchio, F., and Pietrabissa, R., 2002, “Mechanical Behavior of Coronary Stents Investigated through the Finite Element Method,” Journal of Biomechanics, Vol 35, pp. 803-811.

[9] Dotter, C. T. and Judkins, M. P., 1964, “Transluminal Treatment of Arteriosclerotic Obstruction,” Circulation, Vol 30, pp. 654-70.

[10] Cragg, A., Lund, G., Rysavy, J., Casteneda, F., Casteneda, Z. W., and Amplatz, K., 1983, “Nonsurgical Placement of Arterial Endoprostheses: A New Technique Using Nitinol Wire,” Radiology, Vol. 147, pp. 261-63.

[11] Maass, D., Zollikofer, C. L., Largiader, F., and Senning, A., 1984, “Radiological Follow-Up of Transluminally Inserted Vascular Endoprostheses: An Experimental Study Using Expanding Spirals,” Radiology, Vol. 152, pp. 659-63.

[12] Wright, K. C., Wallace, S., Charnsangavej, C., Carrasco, C. H., and Gianturco, C., 1985, “Percutaneous Endovascular Stents: An Experimental Evaluation,” Radiology, Vol. 156, pp. 69-72.

[13] Palmaz, J. C., Sibbit, R. R., Reuter, S. R., Tio, F. O., and Rice, W. J., 1985, “Expandable Intraluminal Graft: A Preliminary Study,” Radiology , Vol. 156 pp. 73-77.

[14] Rousseau, H., Puel, J., and Joffre, F., 1987, “Self-Expanding Endovascular Prosthesis: An Experimental Study,” Radiology, Vol. 164, pp. 709-14.

[15] Sigwart, U., Puel, J., Mirkovitch, V., Joffre, F., and Kappenberger, L., 1987, “Intravascular Stents to Prevent Occlusion and Restenosis after Transluminal Angioplasty,” N Eng1 J Med, Vol. 316, pp 701-06.

[16] Roth, N. M., 2003, “Thin Film Stent,” US Patent 6,527,919.

[17] Her, I., and Midha, A., 1987, “A Compliance Number Concept for Compliant Mechanisms, and Type Synthesis,” ASME Journal of Mechanisms, Transmissions, and Thpe Synthesis, Vol. 109, pp. 348-355.

[18] Serruys, P. W. and Rensing, B. J., 2002, Handbook of Coronary Stents, Martin Dunitz, London, ISBN 1-84184-093-9.
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