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研究生:陳禹銘
研究生(外文):Yu Ming Chen
論文名稱:顱內動脈與側向瘤脈動流場之數值模擬
論文名稱(外文):Numerical Simulations on Pulsatile Flow in an Intracranial Artery with a Sidewall Aneurysm
指導教授:劉通敏劉通敏引用關係丁大為
指導教授(外文):Tong Miin LiouTa-Wei David Ting
學位類別:碩士
校院名稱:國立清華大學
系所名稱:動力機械工程學系
學門:工程學門
學類:機械工程學類
論文種類:學術論文
論文出版年:2004
畢業學年度:92
語文別:中文
論文頁數:134
中文關鍵詞:顱內動脈瘤脈動流壁剪應力壓力
外文關鍵詞:Cerebrovascular side-wall aneurysmPulsatile flowWall shear stressPressure
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有關顱內直型與彎型母管側向動脈瘤之定量速度場量測文獻甚少,尤其缺乏重要但實驗上困難量測的瘤體壓力分佈以及流入瘤體之流量資訊,更無數值模擬相關文獻可說明導致動脈瘤破裂之機制。有鑑於此,本文乃以數值模擬計算探討脈動狀態下曲率半徑(Rm/D)為 與2.5之動脈母管與其上側向動脈瘤的脈動流場特性,旨在經由計算結果與文獻中之於實驗脈動波形(模擬人體內頸動脈,ICA)下的動脈瘤量測數據比較驗證後,進一步提供實驗之文獻中所缺乏的脈動流場特性、瘤體壓力分佈及流入瘤體流量;且因人體後腦循環上之動脈瘤病變對人體的非自律神經系統更為嚴重,故迨數值結果與實驗數據驗證無誤後,再將動脈母管內之流動現象設為人體後腦動脈(PCA)的脈動波形並進行運算。本文實驗脈動現象中之無因次參數,沃門斯理數 為3.9,雷諾數Re最大值為850、最小值為300且平均值為600;PCA脈動現象中之無因次參數,沃門斯理數 為3.9,雷諾數Re最大值為250、最小值為10且平均值為60;而所討論之血流動力因數與相關物理量為瘤內渦漩結構、瘤內活動力、流入瘤體之流量、瘤內速度向量與二次流、瘤璧面剪應力及瘤壁面壓力分佈。結果顯示本文之數值模擬能夠相當合理的重現先前文獻之定性與定量量測結果,而所計算之脈動流場特性除提供相關研究人員參考外,並配合臨床報告以板殼理論之拉普拉斯定理說明導致動脈瘤破裂之機制應為瘤體壓力隨脈動週期之劇烈變化,故減緩此影響動脈瘤破裂之危險因子乃為將來醫療人員以人工支架治癒動脈瘤之設計重點。
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