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研究生:傅彬豪
研究生(外文):Bin-Hau Fu
論文名稱:人工腰椎之設計與力學分析
論文名稱(外文):Design and mechanical analysis of vertebral body replacement
指導教授:蘇侃蘇侃引用關係
指導教授(外文):Hon So
學位類別:碩士
校院名稱:國立臺灣大學
系所名稱:機械工程學研究所
學門:工程學門
學類:機械工程學類
論文種類:學術論文
論文出版年:2004
畢業學年度:92
語文別:中文
論文頁數:162
中文關鍵詞:人工腰椎生物材料胸腰椎
外文關鍵詞:vertebral body replacementbiometrialthoracolumbar spine
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植入人體內的人工腰椎可以減輕病患疼痛、回復脊椎的弁鄔M幫助復原。通常須要使用人工腰椎的情狀是前方脊柱受到傷害而產生骨折或錯位、後方後凸的病變、胸腰椎的腫瘤或其它脊椎的病變。本研究詳細敘述人工腰椎的設計要點、生物材料選擇、技術上的難題和臨床上需要注意的部份。
新開發的人工脊椎替代物被臨床使用之前,必須先做過一連串的體外試驗以評估其是否適用於人體。因為人體的複雜性與目前眾說紛紜的脊椎負荷條件,因此無法比較各家不同人工腰椎性能的優劣好壞。本篇論文從不同的研究團隊整理歸納出邊界條件,並對在不同負荷模式使用不同材料與不同設計的人工腰椎進行比較。
結果對在本篇論文提出的腰椎替代物進行評估。本篇論文也提出對七種腰椎替代物的設計在使用四種不同的材料(鈦合金、鈷鉻鉬合金、不�袗�合金和超高分子量聚乙烯)在不同的負荷模式下(前彎、後彎、扭轉和側彎)的分析結果。
本論文提出設計人工腰椎應該注意的事項。依據此注意事項,發現大部分使用金屬材料的人工腰椎都可以輕易地通過應力分析的測試;經過適當的設計與分析後,也可選用高分子材料製作人工腰椎。
Vertebral body replacements(VBR) have been successfully used to be implanted into the body to relieve patients’ pain, to restore function and to facilitate healing for many years. Possible indications are fractures and dislocations with damage of the anterior column, posttraumatic kyphosis, tumors of the thoracolumbar spine and other spine diseases. The study detailed the design notes, biomaterial selection, technical obstacles and clinical concerns of VBR.
New VBR should be tested in vitro in order to decide whether the implant is accepted for clinical use. Due to the complex and still unknown loading of the spine in vivo, a variety of different test boundary conditions have been used, making comparison of the results of different VBR from different groups almost impossible. This paper using the boundary conditions developed from different working groups analyzes and compares different designs of VBR under different loading modes and biomaterials.
The results show evaluations of designs of VBR mentioned in this paper. The results of seven designs of VBR with four materials(Ti-6Al-4V, CoCrMo alloys, stainless steel 316LV and UHMWPE) under four loading modes(flexion, extension, rotation and lateral bending)are shown.
The conclusion of this study indicated criteria should be noticed in design of VBR. According to such design criteria, this study also indicated that metal VBR can easily satisfies the requirements in stress analysis. After appropriate design and stress analysis, polymer materials can also be used for VBR.
第一章、序論..........................................1
1-1 脊椎之基本解剖生理與生物力學特.................1
1-1-1 人體剖面與基本術語.............................1
1-1-2 脊柱...........................................4
1-1-3 典型脊椎骨的特徵...............................7
1-1-4 各部份脊椎之簡介...............................9
1-1-5 脊柱曲........................................17
1-1-6 小面關........................................20
1-1-7 椎間盤........................................22
1-1-8 韌帶..........................................23
1-2 脊柱病變簡介與人工替代物之使用緣由............25
1-3 文獻回顧......................................30
1-3-1 腰椎之相關文獻回顧............................30
1-3-2 有限元素法利用於腰椎之相關文獻回顧............32
1-3-3 脊椎人工植入物設計之相關文獻回顧..............36
第二章、方法.........................................37
2-1 設計方法......................................37
2-2 人工腰椎的設計重點…..........................43
2-3 人體腰椎的尺寸................................51
2-4 材料的選擇....................................53
2-5 分析方法......................................66
第三章、結果.........................................72
3-1 腰椎替代物設計之評估..........................72
3-1-1 腰椎替代物設計之評估方式......................72
3-1-2 腰椎替代物設計之評估結果......................75
3-2 腰椎替代物設計之有限元素分析模型..............99
3-3 腰椎替代物設計之應力分析.....................104
3-4 腰椎替代物設計之改良.........................118
第四章、討論........................................129
4-1 腰椎替代物設計之討論.........................129
4-2 腰椎替代物使用材料之討論.....................134
第五章、結論........................................138
參考文獻............................................139
附錄一:設計九工程圖................................145
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