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研究生:黃炳杰
研究生(外文):Bing-jie Huang
論文名稱:壓電式微混合器設計製作
論文名稱(外文):Design and Fabrication of piezoelectrical Micro-Mixer
指導教授:羅斯維
指導教授(外文):Sy-Wei Lo
學位類別:碩士
校院名稱:國立雲林科技大學
系所名稱:機械工程系碩士班
學門:工程學門
學類:機械工程學類
論文種類:學術論文
論文出版年:2004
畢業學年度:92
語文別:中文
論文頁數:66
中文關鍵詞:混沌理論微混合器壓電薄膜生醫晶片
外文關鍵詞:Chaos theorembiomedical chippiezoelectric membranemicro-mixer
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微混合器基本上可分為主動式混合器與被動式混合器兩種。主動式混合器較適用於雷諾數極低之流體,其致動機制包括電泳式、注射幫浦、熱氣泡、電磁式、記憶合金式等。本論文提出一體積小、電路簡單、成本低廉的主動式微混合器,以壓電薄膜取代體積龐大且價格昂貴的注射幫浦;既無熱氣泡式熱破壞之疑慮,且可應於非極性之流體,毋需複雜的電磁場設計。
壓電式微混合器係利用混沌理論之原理進行流體混合,由寬度200 �慆的十字形微流道搭配兩個4mm ╳ 4mm ╳ 0.9 mm之振動腔室所組成,整體混合器之大小可控制在 15 mm ╳ 15 mm ╳ 0.9 mm 以下。十字形微流道可分為進行混合之主流道與兩個連接腔室的次流道。當需要混合的兩種液體自主流道之入口端進入時,雙腔室內之薄膜開始交替協調作動,使已充塞在次流道中的液體小幅地往復震盪,藉以干擾主流道中的兩種流體而導致液體混合。腔室間薄膜的協調致動可使次流道的平均流量為零,不致造成主流道流量的變化而產生背壓,適用在雷諾數極低且對背壓敏感的生醫晶片上。而在壓電元件的取得上,則是將市售壓電蜂鳴器薄膜進行裁剪,搭配透明膠帶製成,價格低廉且製作簡單。實驗顯示已成功地以30伏特低電壓、3 赫茲之低頻振動對雷諾數低如0.249之流體完成混合。
Micro-mixers are categorized into active and passive types based on their principles of actuation. The active mixers, actuated by electrokinetical force, syringe pump, hot bubbling, electro-magnetic field, or memory alloys etc, are more suitable for fluidic systems of particularly low Reynolds numbers. This thesis proposes a low cost active micro-mixer of mini integrated size, operating with simple control circuit. It uses piezoelectric membranes to replace the large and expensive syringe pumps. Neither the risk of thermal damage to the reagents as that happens in the hot bubbling system, nor is the complex design of the electro-magnetic field working only for polar fluids involved.
The piezoelectric micro-mixer operating under chaotic mechanism consists of a 200 �慆 wide cross-type micro channel and two 4 mm x 4 mm x 0.9 mm vibrating chambers. The final integrated size less than 15 mm x 15 mm x 1mm can be achieved. The cross-type channel is composed of a main aqueduct where the mixing proceeds, and two branches connecting the chambers. The two reagents flowing into the main aqueduct from the inlet are perturbed by the transverse flow in the branches provoked by the membranes in the chambers and eventually lead to a complete mixing downstream. The vibrations of the membranes in the two chambers are coordinated to obtain a zero time-averaged mass flow across the main channel. Such a feature, together with its ability of active disturbance, makes the present design especially applicable to biomedical chips where minimum backpressure is required. The cost and the fabrication process have been cut down and simplified substantially by adopting the membrane of commercial beepers and transparent tape. Experiments show that mixing for flow of Reynolds number as low as 0.249 can be accomplished by operating voltage 30 V and vibration frequency 3 Hz.
目 錄
中文摘要 ------------------------------------------------------------------ i
英文摘要 ------------------------------------------------------------------ ii
誌謝 ------------------------------------------------------------------ iii
目錄 ------------------------------------------------------------------ iv
表目錄 ------------------------------------------------------------------ v
圖目錄 ------------------------------------------------------------------ vi
符號說明 ------------------------------------------------------------------ viii
第一章 緒論------------------------------------------------------------ 1
1.1 前言------------------------------------------------------------ 1
1.2 文獻回顧------------------------------------------------------ 3
1.3 本文目的------------------------------------------------------ 10
第二章 微混合器之設計及製造------------------------------------ 11
2.1 設計上的構想------------------------------------------------ 11
2.2 微混合器設計------------------------------------------------ 12
2.3 微混合器製作------------------------------------------------ 19
2.4 微流道的製作------------------------------------------------ 22
2.5 微混合器組立------------------------------------------------ 26
第三章 實驗步驟與過程--------------------------------------------- 30
3.1 實驗步驟說明------------------------------------------------ 30
3.2 實驗過程說明------------------------------------------------ 32
第四章 結果與討論--------------------------------------------------- 34
4.1 微混合實驗結果討論--------------------------------------- 34
第五章 結論------------------------------------------------------------ 44
參考文獻 ------------------------------------------------------------------ 46
附件一 ------------------------------------------------------------------ 49
附件二 ------------------------------------------------------------------ 53
自傳 ------------------------------------------------------------------ 51
參考文獻
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