跳到主要內容

臺灣博碩士論文加值系統

(44.201.97.0) 您好!臺灣時間:2024/04/19 14:21
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果 :::

詳目顯示

我願授權國圖
: 
twitterline
研究生:黃士豪
研究生(外文):Shih-Hao Huang
論文名稱:評估OrangeII作為牙齒染色及漂白指示劑之可行性
論文名稱(外文):Evaluation of the feasibility of OrangeⅡ as a tooth staining and bleaching indicator
指導教授:林俊彬林俊彬引用關係
學位類別:碩士
校院名稱:國立臺灣大學
系所名稱:臨床牙醫學研究所
學門:醫藥衛生學門
學類:牙醫學類
論文種類:學術論文
論文出版年:2005
畢業學年度:93
語文別:中文
論文頁數:81
中文關鍵詞:OrangeII牙齒美白
外文關鍵詞:OrangeIITooth Bleaching
相關次數:
  • 被引用被引用:2
  • 點閱點閱:394
  • 評分評分:
  • 下載下載:0
  • 收藏至我的研究室書目清單書目收藏:0
在目前評估牙齒漂白效力的方法中,雖然隨機的臨床試驗可以得到比較直接的結果,但是如果在複雜、耗時的臨床試驗前,能有一套可以精確評估漂白效力的實驗方法,將會是非常有幫助的。在過去有學者使用刻意被全血或茶染色的口外牙齒,來評估牙齒漂白的效果。不過可能會因為所使用的染色源及牙齒本身存在著許多差異等因素的影響,而降低實驗的精確度。因此,本研究的目的為尋找一個適合的牙齒染色及漂白指示劑,用來評估牙齒漂白劑的效力。本實驗的研究方向可分為兩個部分,第一部份為選擇結構和臨床牙齒染色源相似的適合染色劑,且評估所選取染色劑能否確實造成牙齒的變色,並利用過氧化氫加以漂白,而後觀察此染色劑在試管中和過氧化氫的作用變化,以選出一個較適合應用在染色牙齒及試管中的牙齒染色及漂白指示劑。第二部份為利用所選取的染色劑,分別應用在染色牙齒及試管中,來評估不同過氧化氫催化劑的表現,以瞭解在這兩種環境中,對於區分過氧化氫活性的能力是否有所差異。 結果顯示:在所選的染色劑中,Rhodamine B、Fe(III) phthalocyanine、OrangeⅡ 皆可以造成牙齒變色,並可用過氧化氫加以漂白。其中Rhodamine B所造成的牙齒變色,較不容易觀察到時間跟顏色變化的相對關係,且較不易漂白;Fe (III) phthalocyanine 在試管中和過氧化氫作用過快,並不適合當作指示劑。而OrangeⅡ是一個可以應用在牙齒或是試管中的牙齒染色及漂白指示劑。在實驗的第二部份中,無論是在OrangeⅡ染色的牙齒上或是試管中,都可以觀察到加入催化劑後,過氧化氫活性的提升。但在本實驗中, 使用OrangeⅡ染色的牙齒無法區分Mn@sodium-Y及 Fe@sodium-Y 之間催化效力的差異。而OrangeⅡ在試管中,則可以區分出兩種催化劑的催化效力。經由本實驗的結果,OrangeⅡ由於:分子式和臨床上造成牙齒變色的染色源相似;可以造成牙齒的變色,並可藉由過氧化氫加以漂白;在試管中,可以區分出不同條件下過氧化氫的活性。因此,OrangeⅡ是一個適合應用在牙齒及試管中的牙齒染色及漂白指示劑。最後,我們建議可以在複雜、昂貴的臨床試驗前,先在試管中利用OrangeⅡ當作指示劑,對過氧化氫催化劑進行初步篩選。不過,由於在試管中無法完全模擬臨床上複雜的環境,所以對於兩者間結果的可能差異需要更進一步的研究。
Among current methods for estimating the effectiveness of tooth bleaching, randomized controlled clinical studies provided the most effective results. Nevertheless, there is still a need for an appropriate experiment method prior to complicated clinical studies. In the past, bleaching results were estimated by observations on tooth staining caused by blood or tea. However, because of the difference between stain intensity and the tooth itself, it was hard to gain accurate estimates from those experiments. Therefore, the purpose of this study was to search an appropriate indicator as well as to design an appropriate tooth staining and bleaching protocol, which can be used to assess the effectiveness of tooth bleaching with higher accuracy. Our study consisted of two parts. The first part was to select the appropriate dye that had similar structures to the chemical agents that normally cause tooth staining. The correlation with these artificial dyes and its liability to tooth staining and subsequent tooth bleaching was evaluated. The second part was to assess the effectiveness of two different hydrogen peroxide catalysts (Fe@Sodium-Y and Mn@Sodium-Y) in bleaching the stained tooth. This study gave us an insight into the difference in the characteristics of the two hydrogen peroxide catalysts. The results revealed that all selected dyes: Rhodamine B, Fe (III) phthalocyanine and Orange II, would cause the tooth discoloration and could be bleached with hydrogen peroxide. However, no relationship between color changes and time was noted when using Rhodamine B. Moreover, it was noted that the stain caused by Rhodamine B was more difficult to bleach. Fe (III) phthalocyanine reacted with hydrogen peroxides too quickly to be considered as an indicator. On the other hand, Orange II was the most appropriate indicator among those three selected dyes used in the stained tooth and test tube. In the second part of study, after adding in the catalyst, we observed an increase of hydrogen peroxide activity in both stained tooth and test tube methods. In the orange II stained tooth, it is difficult to distinguish the catalysis ability between Fe@Sodium-Y and Mn@Sodium-Y. But catalysis ability can be verified in the test tube of Orange II. In conclusion, Orange II was an appropriate dye considered as an indicator for tooth staining and bleaching not only because it had similar structure to clinical tooth stain, but also it did cause tooth staining and could be bleached. In addition, it was able to differentiate the activeness of hydrogen peroxide under the different conditions. Finally, we suggest tentatively screening out catalysts of hydrogen peroxide with application of Orange II before proceeding with complicated and expensive clinical studies. Unfortunately, this assessment may only act as a rough estimation as the chemical reactivity in vitro may not exactly imitate the complicated clinic environment. Therefore, more research is required to eliminate the potential differences between two results needs.
第一章、前言----------------------------------------------------------------------1
第二章、文獻回顧----------------------------------------------------------3
2.1牙齒的顏色----------------------------------------------------3
2.2牙齒變色的分類及原因--------------------------------------------4
2.3評估牙齒顏色的方式-----------------------------------------------8
2.4牙齒美白的方式----------------------------------------------11
2.5評估牙齒漂白效果的方法--------------------------------14
2.6牙齒漂白劑的成分及牙齒漂白的機制--------------------------16
2.7氫氧自由基的測定方式--------------------------------18
第三章、動機與目的----------------------------------------------------21
第四章、材料與方法---------------------------------------------------22
4.1選擇可以應用於牙齒及試管中,觀察過氧化氫作用的牙齒染色劑-----------------------------------------------22
4.1.1選擇適合的牙齒染色劑----------------------------------------22
4.1.2評估所選取染色劑應用在試管模型中的可行性---------25
4.2利用所選染色劑,應用在染色牙齒及試管中,分別來評估不同過氧化氫催化劑表現------------------------------------------26
4.2.1金屬離子催化劑的製備-------------------------------26
4.2.2不同過氧化氫催化劑在牙齒染色模型上的表現-----27
4.2.3 不同過氧化氫催化劑在Orange Ⅱ 試管模型中的表現--------28
第五章、結果---------------------------------------------------------------30
5.1選擇可以應用於牙齒及試管中,觀察過氧化氫作用的牙齒染色劑-----------------------------------------30
5.1.1選擇適合的牙齒染色劑------------------------------------------30
5.1.2評估所選取染色劑應用在試管模型中的可行性------------33
5.2利用所選染色劑,應用在染色牙齒及試管中,分別來評估不同過氧化氫催化劑表現------------------------------------------34
5.2.1不同過氧化氫催化劑在牙齒染色模型上的表現-------34
5.2.2 不同過氧化氫催化劑在Orange Ⅱ 試管模型中的表現--34
第六章、討論------------------------------------------------------------36
第七章、結論----------------------------------------------------------49
第八章、建議事項--------------------------------------------------------50
參考文獻-------------------------------------------------------51
Addy M, Moran J (1995). Mechanism of stain formation on teeth, in particular associated with metal ions and antiseptics. Advance Dental Research 9(4):450-456.

Addy M, Moran J, Griffiths A, Wills-Wood N J (1985). Extrinsic tooth discoloration by metals and chlorhexidine. Surface protein denaturation or dietary precipitation? British Dental Journal 159: 281-285.

Anitua E, Zabalegui B, Gil J, Gascon F (1990). Internal bleaching of severe tetracycline discolorations: four-year clinical evaluation. Quintessence International 21:783-8.

Attin T, Paque F, Ajam F, Lennon AM (2003). Review of the current status of tooth whitening with the walking bleach technique. International Endodontic Journal 36(5):313-29.

Ari H, Ungor M (2002). In vitro comparison of different types of sodium perborate used for intra-coronal bleaching of discolored teeth. International Endodontic Journal 35:433-6.

Baratieri LN, Ritter AV, Monteiro S (1995). Non-vital tooth bleaching: guideline for clinician. Quintessence International 28(5):305-13.

Bentley C, Leonard RH, Nelson CF, Bentley SA (1999). Quantitation of vital bleaching by computer analysis of photographic images. Journal of the American Dental Association 130:809-816.

Bolt RA, Ten Bosch JJ, Coops JC (1994). Influence of window size in small-window colour measurements, particularly of teeth. Physics in Medicine and Biology 39: 1133-1142.

Bowles WH. Ugwuneri Z (1987). Pulp chamber penetration by hydrogen peroxide following vital bleaching procedures. Journal of Endodontics 13(8):375-7.

Cheng M, Ma W, Li J, Huang Y, Zhao J, Wen YX, Xu Y(2004). Visible-Light-Assisted Degradation of Dye Pollutants over Fe(III)-Loaded Resin in the Presence of H2O2 at Neutral pH Values. Environmental Science & Technology 38(5):1569-1575.

Collins LZ, Maggio B, Liebman J, Blanck M, Lefort S, Waterfield P, Littlewood D, Naeeni M, Schafer F (2004). Clinical evaluation of a novel whitening gel, containing 6% hydrogen peroxide and a standard fluoride toothpaste. Journal of Dentistry 32 (Suppl) 1:13-7.

Cooper JS. Bokmeyer TJ. Bowles WH (1992). Penetration of the pulp chamber by carbamide peroxide bleaching agents. Journal of Endodontics 18(7):315-7.

Dabdin GH (1993). The water in human dental enamel and its diffusional exchange measured by clearance of tritiated water from enamel slabs of varying thickness. Caries Research 27:81-6.

Dayan D, Heifferman A, Gorski M, Begleiter A (1983). Tooth discoloration--extrinsic and intrinsic factors. Quintessence International 14(2):195-9.

Dean HT (1932). Chronic endemic dental fluorosis. Journal of the American Dental Association 107:1269.

Douglas RD (1997). Precision of in vivo colorimetric assessments of teeth. Journal of Prosthetic Dentistry 77:464-470.

Donoghue AM, Ferguson MM (1996). Superficial copper staining of teeth in a brass foundry worker. Occupational Medicine 46(3):233-4.

Eriksen HM, Nordbo H (1978). Extrinsic discoloration of teeth. Journal of Clinical Periodontology 5:229-36.

Feng J, Hu X, Yue PL, Zhu HY, Lu G.Q (2003). Degradation of Azo-dye Orange II by a Photoassisted Fenton Reaction Using a Novel Composite of Iron Oxide and Silicate Nanoparticles as a Catalyst. Industrial & Engineering Chemistry Research 42(10):2058-2066.

Freccia WF, Peters DD, Lorton L, Bernier WE (1982). An in vitro comparison of nonvital bleaching techniques in the discolored tooth. Journal of Endodontics 8(2):70-7.

Freccia WF, Peters DD (1982). A technique for staining extracted teeth: a research and teaching aid for bleaching. Journal of Endodontics 8(2):67-9.

Garberoglio R, Brannstrom M (1976). Scanning electron microscopic investigation of humen dentinal tubules. Archives of Oral Biology 21:355-62.

Gerlach RW, Barker ML, Sagel PA (2002). Objective and subjective whitening response of two self-directed bleaching systems. American Journal of Dentistry 15:7A-12A.

Goldstein RE, Garber DA (1995). Complete Dental Bleaching. Berlin: Quintessence.

Goodkind RJ, Keenan K, Schwabacher WB (1987). Use of a fiberoptic colorimeter for an in vivo color measurement of 2830 anterior teeth. Journal of Prosthetic Dentistry 58:535-542.

Hammad I A (2003). Intrarater repeatability of shade selections with two shade guides. Journal of Prosthetic Dentistry 89:50-53.

Hardman P K, Moore DL, Petteway GH (1985). Stability of hydrogen peroxide as a bleaching agent. General Dentistry 33:121-2.

Hasegawa A, Motonomi A, Ikeda I, Kawaguchi S (2000). Color of natural tooth crown in Japanese people. Color Research and Application 25:43-48.

Hayes PA, Full C, Pinkham J (1986). The etiology and treatment of intrinsic discolorations. Journal of Canada Dental Association 52:217-20.

Haywood VB (1997). Extended bleaching of tetracycline-stained teeth: a case report. Contemporary Esthetics Restoration Practical 1:14-21.

Haywood VB. Heymann HO (1989). Nightguard vital bleaching. Quintessence International 20(3):173-6.

Haywood VB (1992). History, safety, and effectiveness of current bleaching techniques and applications of the nightguard vital bleaching technique. Quintessence International. 23(7):471-88.

Haywood VB, Leonard RH, Nelson CF, Brunson WD (1994). Effectiveness, side effects and long term status of nightguard vital bleaching. Journal of the American Dental Association 125:1219-1226.

Ho S, Goerig AC (1989). An in vitro comparison of different bleaching agents in the discolored tooth. Journal of Endodontics 15(3):106-11.

Holmstrup G, Palm AM, Lambjerg-Hansen H (1988). Bleaching of discoloured root-filled teeth. Endodontics and Dental Traumatology 4:197-210.

Joiner A, Jones N M, Raven S J (1995). Investigation of influencing stain formation utilizing an in situ. Advances in Dental Research 9:471-476.

Joiner A (2004). Tooth colour: a review of the literature. Journal of Dentistry 32 (Suppl):3-12.

Jordan RE, Boksman L (1984). Conservative vital bleaching treatment of discolorated dentition. Compendium of Continuing Education in Dentistry 10:803-807.

Kashima-Tanaka M, Tsujimoto Y, Kawamoto K, Senda N, Ito K, Yamazaki M (2003). Generation of free radicals and/or active oxygen by light or laser irradiation of hydrogen peroxide or sodium hypochlorite. Journal of Endodontics 29:141-3.

Kaneko J, Inoue S, Kawakami S, Sano H (2000). Bleaching effect of sodium percarbonate on discolored pulpless teeth in vitro. Journal of Endodontics 26(1):25-8.

Kihn PW, Barnes DM, Romberg E, Peterson K (2000). A clinical evaluation of 10 percent vs. 15 percent carbamide peroxide tooth-whitening agents. Journal of the American Dental Association 131:1478-1484.

Ko CC, Tantbirojn D, Wang T, Douglas WH (2000). Optical scattering power for characterization of mineral loss. Journal of Dental Research 79:1584-1589.

Letter-Eckman HR (1975). Tetracycline and dental staining. Journal of Infectious Diseases 131(3):286-190.

Liang Li (2003). The biochemistry and physiology of metallic fluoride: action, mechanism, and implications. Critical Reviews in Oral Biology & Medicine 14: 100-114.

Lim MY, Lum SO, Poh RS, Lee GP, Lim KC (2004). An in vitro comparison of the bleaching efficacy of 35% carbamide peroxide with established intracoronal bleaching agents. International Endodontic Journal 37(7):483-8.

Lopez A, Kiwi J (2001). Modeling the performance of an innovative membrane-based reactor. Abatement of azo dye (Orange II) up to biocompatibility. Industrial & Engineering Chemistry Research 40:1852-1858.

Matis BA, Yousef M, Cochran MA, Eckert G J (2002). Degradation of bleaching gels in vivo as a function of tray design and carbamide peroxide concentration. Operative Dentistry 27:12-18.

McCaslin AJ, Haywood VB, Potter BJ, Dickinson GL, Russell CM (1999). Assessing dentin color changes from nightguard vital bleaching. Journal of the American Dental Association 130(10):1485-90.

Mokhlis GR, Matis BA, Cochran MA, Eckert GJ (2000). A clinical evaluation of carbamide peroxide and hydrogen peroxide whitening agents during daytime use. Journal of the American Dental Association 131:1269-1277.

Morley J (1997). The esthetics of anterior tooth aging. Current Opinion in Cosmetic Dentistry 4:35-39.

Nathoo SA (1997). The chemistry and mechanisms of extrinsic and intrinsic discoloration. Journal of the American Dental Association (Suppl) 124(4):6s-10s.

Nutting EB, Poe GS (1963). A new combination for bleaching teeth. Journal of the Southern Californian Dental Association. 31:289.

Nutting EB, Poe GS (1967). Chemical bleaching of discolored endodontically treated teeth. Dental Clinics of North America 11:655-62.

Odioso LL, Gibb RD, Gerlach RW (2000). Impact of demographic, behavioural, and dental care utilization parameters on tooth color and personal satisfaction. Compendium of Continuing Education in Dentistry 21(Suppl):S35-S41.

Okubo S R, Kanawati A, Richards M W, Childress S (1998). Evaluation of visual and instrument shade matching. Journal of Prosthetic Dentistry 80:642-648.

Parra S, Nadtotechenko V, Albers P, Kiwi J (2004). Discoloration of Azo-Dyes at Biocompatible pH-Values through an Fe-Histidine Complex Immobilized on Nafion via Fenton-like Processes. Journal of Physical Chemistry B 108:4439-4448

Paul S, Peter A, Pietroban N, Hammerle CHF (2002). Visual and spectrophotometer shade analysis of human teeth. Journal of Dental Research 81:578-582.

Ronald E. Goldstein, David A. Garber (1995), Complete Dental Bleaching. Quintessence Publishing Co, Inc.

Rosenstiel S F, Gegauff A G, McCafferty R J, Johnston W M (1991). In vitro tooth color change with repeated bleaching. Quintessence International 22:7-12.

Rotstein I (1993). Role of catalase in the elimination of residual hydrogen peroxide following tooth bleaching. Journal of Endodontics 19:567-9.

Rubino M, Barcia JA, Jimenez del Barco L, Romero J (1994). Colour measurement of human teeth and evaluation of a colour guide. Color Research and Application 19:19-22.

Russell MD, Gulfraz M, Moss BW (2000). In vivo measurement of colour changes in natural teeth. Journal of Oral Rehabilitation 27:786-792.

Sato RR, Shiraishi A, Ishibashi K (1994). Using a computer color matching system. A newly developed spectrophotometer designed for clinical application. International Journal of Prosthodontics 7:50-58.

Seghi RR, Johnston WM, O’Brien WJ (1989). Performance assessment of colorimetric devices on dental porcelains. Journal of Dental Research 68:1755-1759.

Spasser HF (1961). A simple bleaching technique using sodium perborate. NewYork State Dental Journal 27:332-4.

Spitzer D, Ten Bosch JJ (1975). The absorption and scattering of light in bovine and human enamel. Calcified Tissue Research 17:129-137.

Sulieman M, Addy M, Rees JS (2003). Development and evaluation of a method in vitro to study the effectiveness of tooth bleaching. Journal of Dentistry 31:415-422.

Sulieman M, Addy M, MacDonald E, Rees JS (2004). The effect of hydrogen peroxide concentration on the outcome of tooth whitening: an in vitro study. Journal of Dentistry 32(4):295-9.

Sulieman M, Addy M, Macdonald E, Rees JS (2005). The bleaching depth of a 35% hydrogen peroxide based in-office product: a study in vitro. Journal of Dentistry 33(1):33-40.

Swift EJ (1988). A method for bleaching discolored vital teeth. Quintessence International 19(9):607-611.

Ten Bosch JJ, Coops JC (1995). Tooth color and reflectance as related to light scattering and enamel hardness. Journal of Dental Research 74:374-380.

Tung FF, Goldstein GR, Jang S, Hittelman E (2002). The repeatability of an intraoral dental colorimeter. Journal of Prosthetic Dentistry 88:585-590.

Vaarkamp J, Ten Bosch JJ, Verdonschot EH (1995). Propagation of light through human dental enamel and dentine. Caries Research 29:8-13.

Vallittu PK, Vallittu ASJ, Lassila VP (1996). Dental aesthetics—a survey of attitudes in different groups of patients. Journal of Dentistry 24:335-338.

Van der Burgt TP, Ten Bosch JJ, Borsboom PCF, Kortsmit WJPM (1990). A comparison of new and conventional methods for quantification of tooth color. Journal of Prosthetic Dentistry 63:155-162.

Walling C, Goose A (1973). Mechanism of ferric ion catalyzed decomposition of hydrogen peroxide effect of organic substrates. Journal of the American Chemical Society 95:2987-2991.

Wallman IS, Hilton HB (1962). Teeth pigmented by tetracycline. Lancet I: 827-829.

Watts A, Addy M (2001). Tooth discolouration and staining: a review of the literature. British Dental Journal 190(6):309-16.

Zack L, Cohen G (1965). Pulp response to externally applied heat. Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics. 19:515-30.

Zijp JR, Ten Bosch JJ, Groenhuis RAJ (1995). HeNe-laser scattering by human dental enamel. Journal of Dental Research 74:1891-1898.
QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top