|
1.Amin, A. R., M. G. Attur, G. D. Thakker, P. D. Patel, P. R. Vyas, R. N. Patel, I. R. Patel, and S. B. Abramson. 1996. A novel mechanism of action of tetracyclines: effects on nitric oxide synthases. Proc Natl Acad Sci U S A 93:14014-9. 2.Amin, A. R., R. N. Patel, G. D. Thakker, C. J. Lowenstein, M. G. Attur, and S. B. Abramson. 1997. Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines. FEBS Lett 410:259-64. 3.Boulares, A. H., A. J. Zoltoski, B. A. Stoica, O. Cuvillier, and M. E. Smulson. 2002. Acetaminophen induces a caspase-dependent and Bcl-XL sensitive apoptosis in human hepatoma cells and lymphocytes. Pharmacol Toxicol 90:38-50. 4.Chen, M., V. O. Ona, M. Li, R. J. Ferrante, K. B. Fink, S. Zhu, J. Bian, L. Guo, L. A. Farrell, S. M. Hersch, W. Hobbs, J. P. Vonsattel, J. H. Cha, and R. M. Friedlander. 2000. Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nat Med 6:797-801. 5.Chu, H. C., Y. L. Lin, H. K. Sytwu, S. H. Lin, C. L. Liao, and Y. C. Chao. 2005. Effects of minocycline on Fas-mediated fulminant hepatitis in mice. Br J Pharmacol 144:275-82. 6.Cornet, S., B. Spinnewyn, S. Delaflotte, C. Charnet, V. Roubert, C. Favre, H. Hider, P. E. Chabrier, and M. Auguet. 2004. Lack of evidence of direct mitochondrial involvement in the neuroprotective effect of minocycline. Eur J Pharmacol 505:111-9. 7.Dai, Y., and A. I. Cederbaum. 1995. Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells. J Pharmacol Exp Ther 273:1497-505. 8.Denicola, A., and R. Radi. 2005. Peroxynitrite and drug-dependent toxicity. Toxicology 208:273-88. 9.Du, Y., Z. Ma, S. Lin, R. C. Dodel, F. Gao, K. R. Bales, L. C. Triarhou, E. Chernet, K. W. Perry, D. L. Nelson, S. Luecke, L. A. Phebus, F. P. Bymaster, and S. M. Paul. 2001. Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Proc Natl Acad Sci U S A 98:14669-74. 10.Fernandez-Gomez, F. J., M. F. Galindo, M. Gomez-Lazaro, C. Gonzalez-Garcia, V. Cena, N. Aguirre, and J. Jordan. 2005. Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions. Neuroscience 133:959-67. 11.Fiorucci, S., E. Antonelli, A. Mencarelli, B. Palazzetti, L. Alvarez-Miller, M. Muscara, P. del Soldato, L. Sanpaolo, J. L. Wallace, and A. Morelli. 2002. A NO-releasing derivative of acetaminophen spares the liver by acting at several checkpoints in the Fas pathway. Br J Pharmacol 135:589-99. 12.Gabler, W. L., J. Smith, and N. Tsukuda. 1992. Comparison of doxycycline and a chemically modified tetracycline inhibition of leukocyte functions. Res Commun Chem Pathol Pharmacol 78:151-60. 13.Goldin, R. D., I. D. Ratnayaka, C. S. Breach, I. N. Brown, and S. N. Wickramasinghe. 1996. Role of macrophages in acetaminophen (paracetamol)-induced hepatotoxicity. J Pathol 179:432-5. 14.Gonzalez, F. J. 2005. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1. Mutat Res 569:101-10. 15.Gotoh, T., and M. Mori. 2006. Nitric Oxide and Endoplasmic Reticulum Stress. Arterioscler Thromb Vasc Biol. 16.Gyamlani, G. G., and C. R. Parikh. 2002. Acetaminophen toxicity: suicidal vs. accidental. Crit Care 6:155-9. 17.He, Y., S. Appel, and W. Le. 2001. Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Res 909:187-93. 18.Hengartner, M. O. 2000. The biochemistry of apoptosis. Nature 407:770-6. 19.Hinson, J. A., S. L. Pike, N. R. Pumford, and P. R. Mayeux. 1998. Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice. Chem Res Toxicol 11:604-7. 20.Jaeschke, H. 2006. How relevant are neutrophils for acetaminophen hepatotoxicity? Hepatology 43:1191-4. 21.Jaeschke, H., and M. L. Bajt. 2006. Intracellular signaling mechanisms of acetaminophen-induced liver cell death. Toxicol Sci 89:31-41. 22.Jaeschke, H., G. J. Gores, A. I. Cederbaum, J. A. Hinson, D. Pessayre, and J. J. Lemasters. 2002. Mechanisms of hepatotoxicity. Toxicol Sci 65:166-76. 23.Kim, R., M. Emi, K. Tanabe, and S. Murakami. 2006. Role of the unfolded protein response in cell death. Apoptosis 11:5-13. 24.Klein, N. C., and B. A. Cunha. 1995. Tetracyclines. Med Clin North Am 79:789-801. 25.Knight, T. R., and H. Jaeschke. 2002. Acetaminophen-induced inhibition of Fas receptor-mediated liver cell apoptosis: mitochondrial dysfunction versus glutathione depletion. Toxicol Appl Pharmacol 181:133-41. 26.Kon, K., J. S. Kim, H. Jaeschke, and J. J. Lemasters. 2004. Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes. Hepatology 40:1170-9. 27.Laskin, D. L., C. R. Gardner, V. F. Price, and D. J. Jollow. 1995. Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. Hepatology 21:1045-50. 28.Laskin, D. L., and K. J. Pendino. 1995. Macrophages and inflammatory mediators in tissue injury. Annu Rev Pharmacol Toxicol 35:655-77. 29.Lawson, J. A., M. A. Fisher, C. A. Simmons, A. Farhood, and H. Jaeschke. 1999. Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice. Toxicol Appl Pharmacol 156:179-86. 30.Li, C. H., S. L. Tzeng, Y. W. Cheng, and J. J. Kang. 2005. Chloramphenicol-induced mitochondrial stress increases p21 expression and prevents cell apoptosis through a p21-dependent pathway. J Biol Chem 280:26193-9. 31.Liu, Z. X., S. Govindarajan, and N. Kaplowitz. 2004. Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity. Gastroenterology 127:1760-74. 32.Liu, Z. X., D. Han, B. Gunawan, and N. Kaplowitz. 2006. Neutrophil depletion protects against murine acetaminophen hepatotoxicity. Hepatology 43:1220-30. 33.Macanas-Pirard, P., N. S. Yaacob, P. C. Lee, J. C. Holder, R. H. Hinton, and G. E. Kass. 2005. Glycogen synthase kinase-3 mediates acetaminophen-induced apoptosis in human hepatoma cells. J Pharmacol Exp Ther 313:780-9. 34.Malhi, H., G. J. Gores, and J. J. Lemasters. 2006. Apoptosis and necrosis in the liver: a tale of two deaths? Hepatology 43:S31-44. 35.Manov, I., M. Hirsh, and T. C. Iancu. 2004. N-acetylcysteine does not protect HepG2 cells against acetaminophen-induced apoptosis. Basic Clin Pharmacol Toxicol 94:213-25. 36.McCullough, K. D., J. L. Martindale, L. O. Klotz, T. Y. Aw, and N. J. Holbrook. 2001. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21:1249-59. 37.Mori, K. 2003. Frame switch splicing and regulated intramembrane proteolysis: key words to understand the unfolded protein response. Traffic 4:519-28. 38.Nakagawa, T., and J. Yuan. 2000. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 150:887-94. 39.Oyadomari, S., K. Takeda, M. Takiguchi, T. Gotoh, M. Matsumoto, I. Wada, S. Akira, E. Araki, and M. Mori. 2001. Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway. Proc Natl Acad Sci U S A 98:10845-50. 40.Ray, S. D., L. M. Kamendulis, M. W. Gurule, R. D. Yorkin, and G. B. Corcoran. 1993. Ca2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen. Faseb J 7:453-63. 41.Ray, S. D., V. R. Mumaw, R. R. Raje, and M. W. Fariss. 1996. Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment. J Pharmacol Exp Ther 279:1470-83. 42.Ray, S. D., C. L. Sorge, J. L. Raucy, and G. B. Corcoran. 1990. Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen-induced liver injury. Toxicol Appl Pharmacol 106:346-51. 43.Ryan, M. E., and R. A. Ashley. 1998. How do tetracyclines work? Adv Dent Res 12:149-51. 44.Salas, V. M., and G. B. Corcoran. 1997. Calcium-dependent DNA damage and adenosine 3',5'-cyclic monophosphate-independent glycogen phosphorylase activation in an in vitro model of acetaminophen-induced liver injury. Hepatology 25:1432-8. 45.Wang, J., Q. Wei, C. Y. Wang, W. D. Hill, D. C. Hess, and Z. Dong. 2004. Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria. J Biol Chem 279:19948-54. 46.Wang, X., S. Zhu, M. Drozda, W. Zhang, I. G. Stavrovskaya, E. Cattaneo, R. J. Ferrante, B. S. Kristal, and R. M. Friedlander. 2003. Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease. Proc Natl Acad Sci U S A 100:10483-7. 47.Whiteman, M., and B. Halliwell. 1997. Prevention of peroxynitrite-dependent tyrosine nitration and inactivation of alpha1-antiproteinase by antibiotics. Free Radic Res 26:49-56. 48.Xu, W., L. Liu, I. G. Charles, and S. Moncada. 2004. Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response. Nat Cell Biol 6:1129-34. 49.Yoshida, H., T. Matsui, A. Yamamoto, T. Okada, and K. Mori. 2001. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107:881-91. 50.Yrjanheikki, J., R. Keinanen, M. Pellikka, T. Hokfelt, and J. Koistinaho. 1998. Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc Natl Acad Sci U S A 95:15769-74. 51.Zhang, H., J. Cook, J. Nickel, R. Yu, K. Stecker, K. Myers, and N. M. Dean. 2000. Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis. Nat Biotechnol 18:862-7. 52.Zhu, S., I. G. Stavrovskaya, M. Drozda, B. Y. Kim, V. Ona, M. Li, S. Sarang, A. S. Liu, D. M. Hartley, C. Wu du, S. Gullans, R. J. Ferrante, S. Przedborski, B. S. Kristal, and R. M. Friedlander. 2002. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 417:74-8.
|