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研究生:王宣惠
研究生(外文):Hsuan-Hui Wang
論文名稱:3DRP正子造影影像重建之改良3DRP正子造影影像重建之改良
論文名稱(外文):An Improved 3DRP PET Image Reconstruction Method
指導教授:鄭為民鄭為民引用關係
指導教授(外文):Wei-Min Jeng
學位類別:碩士
校院名稱:東吳大學
系所名稱:資訊科學系
學門:工程學門
學類:電資工程學類
論文種類:學術論文
論文出版年:2006
畢業學年度:94
語文別:中文
論文頁數:34
中文關鍵詞:正子斷層掃瞄造影術3DRPSSRB影像重建
外文關鍵詞:PET3DRPSSRBimage reconstruction
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正子斷層掃瞄造影術(Positron Emission Tomography),簡稱PET,可以幫助醫師們及早發現初期腫瘤的徵兆,對於癌症的診斷有很大的幫助,在人類醫學上已為不可或缺的技術。
在PET的重建技術可分為兩大類:直接分析法(Direct Analytical Method)以及迭代式影像重組法(Iterative Reconstruction Method)。針對醫療影像的重建,三維的影像重建技術有效的改善傳統二維重建影像的品質,但影像品質與資料的敏感度仍受限於儀器物理性質的限制。在直接分析法中,3DRP對第一次影像估計對正向投影來估計未收集到的投影資料,但僅考慮正向投影資料,並未採用斜向投影資料。
本研究所提出的3DRP-SSRB方法中,使用SSRB來對第一次影像估計前之投影資料進行重分割,加入斜向投影資料的考量來提升了第一次影像估計的敏感度,以便提高整體機器收集資料的敏感度,而使得最後重建影像的品質獲得改善。對於影像品質及機器敏感度此兩大影像重建結果之因素作一詳細的分析與實驗,並取得具體的量化或實驗的數據。
本研究使用MATLAB所產生的影像,採用工具軟體進行模擬,對本研究方法3DRP-SSRB與二維的FBP、原3DRP兩方法的重建影像進行比較,所有重建的影像切面大部分皆呈現出較好的MSE值;而根據Axial Compression的壓縮概念,取不同的span值所重建的影像進行比較,發現採用不同span值對影像的品質並沒有太大的影響。
PET(Positron Emission Tomography) is an important technique in medical imaging. PET helps doctors to find the tumour early and is a great help for diagnosing cancer.
The image reconstruction in PET can be divided into two categories, direct analytical methods and iterative reconstruction methods. According to the image reconstruction in PET, the quality of traditional two-dimensional image reconstruction has been efficiently improved by three-dimensional image reconstruction, but the sensitivity of the data and the quality of the image are restricted by the limit of modality physics. In analytical image reconstruction algorithm, 3DRP method compensates the unmeasured events by forward projection based on the initial direct image estimate. However, the original 3DRP method merely depends on the parallel projections without taking into account the oblique projections.
In our proposed 3DRP-SSRB method, we improve the first image estimate by incorporating the rebinned oblique data. SSRB method was used to perform the rebinning operation to make use of the oblique projection data to improve the sensitivity information. And then project the improved image estimate forward and reconstruct the final image. Conflicting parameters of reconstructed image quality of 3DRP are experimented by simulated thee-dimensional phantom study with regard to both system sensitivity and image quality factors.
PET simulation software package was used to conduct the experiment along with the MATLAB software to evaluate the effectiveness of two-dimensional FBP, 3DRP, and our proposed 3DRP-SSRB methods. The result demonstrated its better image quality by having better mean squared error numbers in most of output image slices. According to the concept of axial compression, different span value does not have too great influence on the quality of the reconstructed image.
誌謝 i
摘要 ii
ABSTRACT iii
目錄 v
表目錄 vi
圖目錄 vii
1 研究動機 1
2 文獻探討 4
2.1 PET(Positron Emission Tomography) 4
2.2 PET影像重建機制 5
2.3 濾波反投影法 7
2.4 Colsher理論 8
2.5 3DRP影像重建法 11
3 研究方法 14
3.1 STIR程式 14
3.2 架構說明 18
3.3 實作說明 20
4 實驗分析 23
5 結論 31
參考文獻 33
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