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研究生:黃昭瑢
研究生(外文):Chao-Jung Huang
論文名稱:台北市社區中老年人不寧腿症候群與週期性肢體抽動障礙之危險因子與盛行率探討
論文名稱(外文):The risk factors and prevalence rate of restless legs syndrome (RLS) and periodic limb movement disorder (PLMD) in Taipei community middle-aged and elderly people.
指導教授:于漱于漱引用關係
指導教授(外文):Shu Yu
學位類別:碩士
校院名稱:國立陽明大學
系所名稱:社區護理研究所
學門:醫藥衛生學門
學類:護理學類
論文種類:學術論文
論文出版年:2006
畢業學年度:94
語文別:中文
論文頁數:100
中文關鍵詞:不寧腿症候群週期性肢體抽動障礙國際不寧腿症候群研究團體國際睡眠障礙分類盛行率
外文關鍵詞:Restless Legs Syndrome (RLS)Periodic Limb Movement Disorder (PLMD)International Restless Leg Syndrome Study Group (IRLSSG)International Classification of Sleep Disorders (ICSD)prevalence rate
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不寧腿症候群(Restless Legs Syndrome, RLS)與週期性肢體抽動障礙(Periodic Limb Movement Disorder, PLMD)是影響中老年人睡眠的因素之一,過去研究顯示此二個問題往往被低估,但在國內更是缺乏此方面研究。本研究主要目的為發展不寧腿症候群與週期性肢體抽動障礙篩檢工具,並探討不寧腿症候群與週期性肢體抽動障礙危險因子相關性,以及盛行率。發展篩檢工具量表方面,不寧腿症候群篩檢量表依據國際不寧腿症候群研究團體(International Restless Leg Syndrome Study Group, IRLSSG)提出的四個不寧腿症候群主要診斷所擬定的。週期性肢體抽動障礙篩檢量表則依據國際睡眠障礙分類(International Classification of Sleep Disorders, ICSD)對於週期性肢體抽動障礙診斷標準所擬定。不寧腿症候群篩檢工具其敏感性(sensitivity)為83.3%與特異性(specificity)為100.0%,效度方面專家效度指標(Content Validity Index;CVI)為1.0,信度方面內在一致性KR 20(Kuder-Richardson formula 20)為0.89。週期性肢體抽動障礙篩檢工具敏感性為56.7%與特異性為100.0%,效度方面專家效度指標為0.97,信度方面內在一致性KR 20為0.63。研究結果發現有飲酒、喝咖啡或茶習慣、沒有規律運動、患有精神疾病、服用鎮靜安眠藥,以及抗焦慮劑與不寧腿症候群有顯著相關(p < 0.05)。性別、年齡、教育程度、BMI、有飲酒、沒有規律運動習慣、患有高血壓、服用鎮靜安眠藥與週期性肢體抽動障礙有顯著的相關(p < 0.05)。台北市中老年人不寧腿症候群盛行率為1.2%,其中男性盛行率為0.8%,女性盛行率為1.3%。台北市中老年人週期性肢體抽動障礙盛行率為1.8%,女性盛行率為3.0%。本研究為國內首篇不寧腿症候群與週期性肢體抽動障礙初步探討研究,期待有更多的研究進一步來探討。
ABSTRACT
Restless Legs Syndrome (RLS) and Periodic Limb Movement Disorder (PLMD), defined as diseases affecting the elders' sleep, have been often underestimated, and related research reports are available in Taiwan. The purpose of this research is to develop screening tools for RLS and PLMD, and discuss the relatedness between risk factors of these two diseases as well as their prevalence. A scale to evaluate RLS was developed, according to the four major diagnoses of RLS, brought up by International Restless Leg Syndrome Study Group (IRLSSG), whereas the screening scale for PLMD was developed, based on the diagnostic criteria for the disease by International Classification of Sleep Disorders (ICSD). In the research, the sensitivity, specificity, content validity index (CVI) and internal consistency, KR20 (Kuder-Richardson formula 20) of RLS screening scale are respectively 83.3%, 100.0%, 1.0 and 0.89, and that of PLMD screening scale are 56.7%, 100.0%, 0.97 and 0.63 respectively. The research discovered that drinking alcohol, caffeine, a lack of regular exercise, mental disorder, and taking hypnotics and anxiolytics are significantly related to RLS (p < 0.05), and PLMD is significantly associated with gender, age, education, BMI, drinking alcohol, a lack of regular exercise, hypertension, and taking hypnotics (p < 0.05). RLS has a prevalence rate of 1.2% for the elders in Taipei, of whom the prevalence rate for men is 0.8% and 1.3% for women. The prevalence rate of PLMD for the elders in Taipei is 1.8% and 3.0% for women. The research report is the first initial research on RLS and PLMD, and future research will be required to study these two diseases further.

Keywords: Restless Legs Syndrome (RLS), Periodic Limb Movement Disorder (PLMD), International Restless Leg Syndrome Study Group (IRLSSG), International Classification of Sleep Disorders (ICSD), Prevalence rate.
目 錄
第一章 研究動機與重要性……………………………………………01
第二章 文獻探討………………………………………………………04
第一節 不寧腿症候群與週期性肢體抽動障礙之定義………………04
第二節 不寧腿症候群與週期性肢體抽動障礙診斷與症狀…………07
第三節 不寧腿症候群與週期性肢體抽動障礙之盛行率……………14
第四節 不寧腿症候群與週期性肢體抽動障礙診斷標準與篩檢工具18
第五節 不寧腿症候群與週期性肢體抽動障礙相關危險因子………24
第三章 研究架構與研究目的…………………………………………33
第一節 研究架構………………………………………………………33
第二節 名詞界定………………………………………………………34
第三節 研究目的與假設………………………………………………36
第四章 研究方法………………………………………………………37
第一節 研究設計………………………………………………………37
第二節 研究對象………………………………………………………37
第三節 研究工具………………………………………………………48
第四節 研究步驟………………………………………………………51
第五節 研究倫理考量…………………………………………………54
第六節 資料分析方法…………………………………………………55
第五章 研究結果 ……………………………………………………56
第一節 背景介紹…………………………………………………56
第二節 不寧腿症候群危險因子方面……………………………57
第三節 週期性肢體抽動障礙危險因子方面……………………61
第四節 不寧腿症候群篩檢工具檢測與盛行率調查方面………67
第五節 週期性肢體抽動障礙篩檢工具檢測與盛行率調查方面70
第六章 討論……………………………………………………………75
第一節 不寧腿症候群危險因子方面……………………………75
第二節 週期性肢體抽動障礙危險因子方面……………………81
第三節 不寧腿症候群之盛行率調查方面………………………86
第四節 週期性肢體抽動障礙之盛行率調查方面………………88
第七章 結論與建議……………………………………………………90
第一節 研究結論…………………………………………………90
第二節 研究限制與建議…………………………………………92
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