|
1.Hostetter, T.H. and M.E. Rosenberg, Hemodynamic effects of glomerular permselectivity. Am J Nephrol, 1990. 10 Suppl 1: p. 24-7.
2.Lapuz, M.H., Diabetic nephropathy. Med Clin North Am, 1997. 81(3): p. 679-88.
3.Korner, A., A.C. Eklof, G. Celsi, and A. Aperia, Increased renal metabolism in diabetes. Mechanism and functional implications. Diabetes, 1994. 43(5): p. 629-33.
4.Levy, J., J.R. Gavin, 3rd, and J.R. Sowers, Diabetes mellitus: a disease of abnormal cellular calcium metabolism? Am J Med, 1994. 96(3): p. 260-73.
5.Pugliese, G., F. Pricci, P. Mene, G. Romeo, I. Nofroni, S. Giannini, B. Cresci, G. Galli, C.M. Rotella, U. Di Mario, and F. Pugliese, High glucose level unmasks a genetic predisposition to enhanced extracellular matrix production in mesangial cells from the Milan normotensive strain. J Am Soc Nephrol, 1997. 8(3): p. 406-14.
6.Sharma, K., F.N. Ziyadeh, B. Alzahabi, T.A. McGowan, S. Kapoor, B.R. Kurnik, P.B. Kurnik, and L.S. Weisberg, Increased renal production of transforming growth factor-beta1 in patients with type II diabetes. Diabetes, 1997. 46(5): p. 854-9.
7.Craven, P.A., R.K. Studer, H. Negrete, and F.R. DeRubertis, Protein kinase C in diabetic nephropathy. J Diabetes Complications, 1995. 9(4): p. 241-5.
8.Kreisberg, J.I., J.A. Garoni, R. Radnik, and S.H. Ayo, High glucose and TGF beta 1 stimulate fibronectin gene expression through a cAMP response element. Kidney Int, 1994. 46(4): p. 1019-24.
9.Riser, B.L., M. Denichilo, P. Cortes, C. Baker, J.M. Grondin, J. Yee, and R.G. Narins, Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis. J Am Soc Nephrol, 2000. 11(1): p. 25-38.
10.Wolf, G. and F.N. Ziyadeh, Cellular and molecular mechanisms of proteinuria in diabetic nephropathy. Nephron Physiol, 2007. 106(2): p. p26-31.
11.Leehey, D.J., A.K. Singh, N. Alavi, and R. Singh, Role of angiotensin II in diabetic nephropathy. Kidney Int Suppl, 2000. 77: p. S93-8.
12.Price, D.A., L.E. Porter, M. Gordon, N.D. Fisher, J.M. De''Oliveira, L.M. Laffel, D.R. Passan, G.H. Williams, and N.K. Hollenberg, The paradox of the low-renin state in diabetic nephropathy. J Am Soc Nephrol, 1999. 10(11): p. 2382-91.
13.Wolf, G., A. Hamann, D.C. Han, U. Helmchen, F. Thaiss, F.N. Ziyadeh, and R.A. Stahl, Leptin stimulates proliferation and TGF-beta expression in renal glomerular endothelial cells: potential role in glomerulosclerosis [seecomments]. Kidney Int, 1999. 56(3): p. 860-72.
14.Fan, J.M., Y.Y. Ng, P.A. Hill, D.J. Nikolic-Paterson, W. Mu, R.C. Atkins, and H.Y. Lan, Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro. Kidney Int, 1999. 56(4): p. 1455-67.
15.Brodin, G., P. ten Dijke, K. Funa, C.H. Heldin, and M. Landstrom, Increased smad expression and activation are associated with apoptosis in normal and malignant prostate after castration. Cancer Res, 1999. 59(11): p. 2731-8.
16.Chen, R.H., R. Ebner, and R. Derynck, Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-beta activities. Science, 1993. 260(5112): p. 1335-8.
17.Carcamo, J., F.M. Weis, F. Ventura, R. Wieser, J.L. Wrana, L. Attisano, and J. Massague, Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin. Mol Cell Biol, 1994. 14(6): p. 3810-21.
18.Wrana, J.L., TGF-beta receptors and signalling mechanisms. Miner Electrolyte Metab, 1998. 24(2-3): p. 120-30.
19.Tsukazaki, T., T.A. Chiang, A.F. Davison, L. Attisano, and J.L. Wrana, SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor. Cell, 1998. 95(6): p. 779-91.
20.Massague, J., TGF-beta signal transduction. Annu Rev Biochem, 1998. 67: p. 753-91.
21.Shi, Y. and J. Massague, Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell, 2003. 113(6): p. 685-700.
22.Usui, T., M. Takase, Y. Kaji, K. Suzuki, K. Ishida, T. Tsuru, K. Miyata, M. Kawabata, and H. Yamashita, Extracellular matrix production regulation by TGF-beta in corneal endothelial cells. Invest Ophthalmol Vis Sci, 1998. 39(11): p. 1981-9.
23.Nakamura, T., D. Miller, E. Ruoslahti, and W.A. Border, Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-beta 1. Kidney Int, 1992. 41(5): p. 1213-21.
24.Oh, J.H., H. Ha, M.R. Yu, and H.B. Lee, Sequential effects of high glucose on mesangial cell transforming growth factor-beta 1 and fibronectin synthesis. Kidney Int, 1998. 54(6): p. 1872-8.
25.Baricos, W.H., S.L. Cortez, S.S. el-Dahr, and H.W. Schnaper, ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/MMP-2 cascade. Kidney Int, 1995. 47(4): p. 1039-47.
26.Schenk, O., H. Ling, K. Sebekova, S. Vamvakas, and A. Heidland, High-glucose media enhance the responsiveness of tubular cells to growth promoters: effect on lysosomal cathepsins and protein degradation. Miner Electrolyte Metab, 1998. 24(4): p. 254-60.
27.Schneider, A., U. Panzer, G. Zahner, U. Wenzel, G. Wolf, F. Thaiss, U. Helmchen, and R.A. Stahl, Monocyte chemoattractant protein-1 mediates collagen deposition in experimental glomerulonephritis by transforming growth factor-beta. Kidney Int, 1999. 56(1): p. 135-44.
28.Tada, H. and S. Isogai, The fibronectin production is increased by thrombospondin via activation of TGF-beta in cultured human mesangial cells. Nephron, 1998. 79(1): p. 38-43.
29.Ding, G., H. van Goor, S.D. Ricardo, J.M. Orlowski, and J.R. Diamond, Oxidized LDL stimulates the expression of TGF-beta and fibronectin in human glomerular epithelial cells. Kidney Int, 1997. 51(1): p. 147-54.
30.Kamata, T., E. Muso, M. Yashiro, T. Kawamura, A. Oyama, H. Matsushima, E. Takeuchi, H. Yoshida, and S. Sasayama, Up-regulation of glomerular extracellular matrix and transforming growth factor-beta expression in RF/J mice. Kidney Int, 1999. 55(3): p. 864-76.
31.Rider, V., M. Piva, M.E. Cohen, and D.L. Carlone, Alternative splicing and differential targeting of fibroblast growth factor receptor 1 in the pregnant rat uterus. Endocrinology, 1995. 136(7): p. 3137-45.
32.Mutsaers, S.E., I. Kalomenidis, N.A. Wilson, and Y.C. Lee, Growth factors in pleural fibrosis. Curr Opin Pulm Med, 2006. 12(4): p. 251-8.
33.Puligilla, C., F. Feng, K. Ishikawa, S. Bertuzzi, A. Dabdoub, A.J. Griffith, B. Fritzsch, and M.W. Kelley, Disruption of fibroblast growth factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairment. Dev Dyn, 2007. 236(7): p. 1905-17.
34.Khalil, N., Y.D. Xu, R. O''Connor, and V. Duronio, Proliferation of pulmonary interstitial fibroblasts is mediated by transforming growth factor-beta1-induced release of extracellular fibroblast growth factor-2 and phosphorylation of p38 MAPK and JNK. J Biol Chem, 2005. 280(52): p. 43000-9.
35.Hetzel, M., M. Bachem, D. Anders, G. Trischler, and M. Faehling, Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts. Lung, 2005. 183(4): p. 225-37.
36.Strutz, F., M. Zeisberg, A. Renziehausen, B. Raschke, V. Becker, C. van Kooten, and G. Muller, TGF-beta 1 induces proliferation in human renal fibroblasts via induction of basic fibroblast growth factor (FGF-2). Kidney Int, 2001. 59(2): p. 579-92.
37.Strutz, F., M. Zeisberg, F.N. Ziyadeh, C.Q. Yang, R. Kalluri, G.A. Muller, and E.G. Neilson, Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int, 2002. 61(5): p. 1714-28.
38.Kruithof, E.K., A. Gudinchet, and F. Bachmann, Plasminogen activator inhibitor 1 and plasminogen activator inhibitor 2 in various disease states. Thromb Haemost, 1988. 59(1): p. 7-12.
39.Hamsten, A., M.N. Mannila, and A. Silveira, Quest for genes regulating plasma fibrinogen concentration: still a long way to go. Arterioscler Thromb Vasc Biol, 2005. 25(6): p. 1100-1.
40.Hamsten, A., B. Wiman, U. de Faire, and M. Blomback, Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med, 1985. 313(25): p. 1557-63.
41.Kohler, H.P. and P.J. Grant, Plasminogen-activator inhibitor type 1 and coronary artery disease. N Engl J Med, 2000. 342(24): p. 1792-801.
42.Bradham, D.M., A. Igarashi, R.L. Potter, and G.R. Grotendorst, Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol, 1991. 114(6): p. 1285-94.
43.Grotendorst, G.R., Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts. Cytokine Growth Factor Rev, 1997. 8(3): p. 171-9.
44.Oemar, B.S. and T.F. Luscher, Connective tissue growth factor. Friend or foe? Arterioscler Thromb Vasc Biol, 1997. 17(8): p. 1483-9.
45.Igarashi, A., H. Okochi, D.M. Bradham, and G.R. Grotendorst, Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell, 1993. 4(6): p. 637-45. 46.Herbst, R.S., Review of epidermal growth factor receptor biology. Int J Radiat Oncol Biol Phys, 2004. 59(2 Suppl): p. 21-6.
47.Harris, R.C., E. Chung, and R.J. Coffey, EGF receptor ligands. Exp Cell Res, 2003. 284(1): p. 2-13.
48.Bogdan, S. and C. Klambt, Epidermal growth factor receptor signaling. Curr Biol, 2001. 11(8): p. R292-5.
49.Andl, C.D., T. Mizushima, K. Oyama, M. Bowser, H. Nakagawa, and A.K. Rustgi, EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes. Am J Physiol Gastrointest Liver Physiol, 2004. 287(6): p. G1227-37.
50.Baselga, J., Why the epidermal growth factor receptor? The rationale for cancer therapy. Oncologist, 2002. 7 Suppl 4: p. 2-8.
51.Hsieh, M.H., Y.F. Fang, W.C. Chang, H.P. Kuo, S.Y. Lin, H.P. Liu, C.L. Liu, H.C. Chen, Y.C. Ku, Y.T. Chen, Y.H. Chang, Y.T. Chen, B.L. Hsi, S.F. Tsai, and S.F. Huang, Complex mutation patterns of epidermal growth factor receptor gene associated with variable responses to gefitinib treatment in patients with non-small cell lung cancer. Lung Cancer, 2006. 53(3): p. 311-22.
52.Nouwen, E.J., W.A. Verstrepen, and M.E. De Broe, Epidermal growth factor in acute renal failure. Ren Fail, 1994. 16(1): p. 49-60.
53.Sayed-Ahmed, N., N. Besbas, J. Mundy, E. Muchaneta-Kubara, G. Cope, C. Pearson, and M. el Nahas, Upregulation of epidermal growth factor and its receptor in the kidneys of rats with streptozotocin-induced diabetes. Exp Nephrol, 1996. 4(6): p. 330-9.
54.Norman, J., B. Badie-Dezfooly, E.P. Nord, I. Kurtz, J. Schlosser, A. Chaudhari, and L.G. Fine, EGF-induced mitogenesis in proximal tubular cells: potentiation by angiotensin II. Am J Physiol, 1987. 253(2 Pt 2): p. F299-309.
55.Okada, S. and J.E. Pessin, Insulin and epidermal growth factor stimulate a conformational change in Rap1 and dissociation of the CrkII-C3G complex. J Biol Chem, 1997. 272(45): p. 28179-82.
56.Creely, J.J., S.J. DiMari, A.M. Howe, C.P. Hyde, and M.A. Haralson, Effects of epidermal growth factor on collagen synthesis by an epithelioid cell line derived from normal rat kidney. Am J Pathol, 1990. 136(6): p. 1247-57.
57.Flamant, M., P.L. Tharaux, S. Placier, D. Henrion, T. Coffman, C. Chatziantoniou, and J.C. Dussaule, Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice. Faseb J, 2003. 17(2): p. 327-9.
58.Gilbert, R.E., A. Cox, P.G. McNally, L.L. Wu, M. Dziadek, M.E. Cooper, and G. Jerums, Increased epidermal growth factor in experimental diabetes related kidney growth in rats. Diabetologia, 1997. 40(7): p. 778-85.
59.Kassab, E., S.I. McFarlane, and J.R. Sower, Vascular complications in diabetes and their prevention. Vasc Med, 2001. 6(4): p. 249-55.
60.Khan, A.J., S.E. Fligiel, L. Liu, R. Jaszewski, A. Chandok, and A.P. Majumdar, Induction of EGFR tyrosine kinase in the gastric mucosa of diabetic rats. Proc Soc Exp Biol Med, 1999. 221(2): p. 105-10.
61.Stocklin, E., F. Botteri, and B. Groner, An activated allele of the c-erbB-2 oncogene impairs kidney and lung function and causes early death of transgenic mice. J Cell Biol, 1993. 122(1): p. 199-208.
62.Del Castillo, G., M.M. Murillo, A. Alvarez-Barrientos, E. Bertran, M. Fernandez, A. Sanchez, and I. Fabregat, Autocrine production of TGF-beta confers resistance to apoptosis after an epithelial-mesenchymal transition process in hepatocytes: Role of EGF receptor ligands. Exp Cell Res, 2006. 312(15): p. 2860-71.
63.Francois, H., S. Placier, M. Flamant, P.L. Tharaux, D. Chansel, J.C. Dussaule, and C. Chatziantoniou, Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition. Faseb J, 2004. 18(7): p. 926-8. 64.Lautrette, A., S. Li, R. Alili, S.W. Sunnarborg, M. Burtin, D.C. Lee, G. Friedlander, and F. Terzi, Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach. Nat Med, 2005. 11(8): p. 867-74.
65.Uchiyama-Tanaka, Y., H. Matsubara, Y. Mori, A. Kosaki, N. Kishimoto, K. Amano, S. Higashiyama, and T. Iwasaka, Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells. Kidney Int, 2002. 62(3): p. 799-808.
66.Wakeling, A.E., S.P. Guy, J.R. Woodburn, S.E. Ashton, B.J. Curry, A.J. Barker, and K.H. Gibson, ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res, 2002. 62(20): p. 5749-54.
67.Douglass, E.C., Development of ZD1839 in colorectal cancer. Semin Oncol, 2003. 30(3 Suppl 6): p. 17-22.
68.Feng, F.Y., C.A. Lopez, D.P. Normolle, S. Varambally, X. Li, P.Y. Chun, M.A. Davis, T.S. Lawrence, and M.K. Nyati, Effect of epidermal growth factor receptor inhibitor class in the treatment of head and neck cancer with concurrent radiochemotherapy in vivo. Clin Cancer Res, 2007. 13(8): p. 2512-8.
69.Lorusso, P.M., Phase I studies of ZD1839 in patients with common solid tumors. Semin Oncol, 2003. 30(1 Suppl 1): p. 21-9.
70.Moasser, M.M., A. Basso, S.D. Averbuch, and N. Rosen, The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells. Cancer Res, 2001. 61(19): p. 7184-8.
71.Eddy, A.A., Molecular insights into renal interstitial fibrosis. J Am Soc Nephrol, 1996. 7(12): p. 2495-508.
72.Okada, H., F. Strutz, T.M. Danoff, and E.G. Neilson, Possible pathogenesis of renal fibrosis. Kidney Int Suppl, 1996. 54: p. S37-8.
73.Essawy, M., O. Soylemezoglu, E.C. Muchaneta-Kubara, J. Shortland, C.B. Brown, and A.M. el Nahas, Myofibroblasts and the progression of diabetic nephropathy. Nephrol Dial Transplant, 1997. 12(1): p. 43-50.
74.Saad, S., V.A. Stevens, L. Wassef, P. Poronnik, D.J. Kelly, R.E. Gilbert, and C.A. Pollock, High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule. Kidney Int, 2005. 68(3): p. 985-97.
75.Bach, L.A., M.A. Gallicchio, E.A. McRobert, A. Tikoo, and M.E. Cooper, Effects of advanced glycation end products on ezrin-dependent functions in LLC-PK1 proximal tubule cells. Ann N Y Acad Sci, 2005. 1043: p. 609-16.
76.Nouwen, E.J. and M.E. De Broe, EGF and TGF-alpha in the human kidney: identification of octopal cells in the collecting duct. Kidney Int, 1994. 45(5): p. 1510-21.
77.Muszynski, K.W., D. Thompson, C. Hanson, R. Lyons, A. Spadaccini, and S.K. Ruscetti, Growth factor-independent proliferation of erythroid cells infected with Friend spleen focus-forming virus is protein kinase C dependent but does not require Ras-GTP. J Virol, 2000. 74(18): p. 8444-51.
78.Han, D.C., M. Isono, B.B. Hoffman, and F.N. Ziyadeh, High glucose stimulates proliferation and collagen type I synthesis in renal cortical fibroblasts: mediation by autocrine activation of TGF-beta. J Am Soc Nephrol, 1999. 10(9): p. 1891-9.
79.Ziyadeh, F.N., Mediators of diabetic renal disease: the case for tgf-Beta as the major mediator. J Am Soc Nephrol, 2004. 15 Suppl 1: p. S55-7.
80.Carcamo, J., A. Zentella, and J. Massague, Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex. Mol Cell Biol, 1995. 15(3): p. 1573-81.
81.Virelizier, J.L., How HIV may escape the activating effects of TNF. Res Immunol, 1994. 145(8-9): p. 690-3; discussion 694-6.
82.Hatakeyama, D., O. Kozawa, M. Niwa, H. Matsuno, H. Ito, K. Kato, N. Tatematsu, T. Shibata, and T. Uematsu, Upregulation by retinoic acid of transforming growth factor-beta-stimulated heat shock protein 27 induction in osteoblasts: involvement of mitogen-activated protein kinases. Biochim Biophys Acta, 2002. 1589(1): p. 15-30.
83.Razzaque, M.S., C.S. Foster, and A.R. Ahmed, Role of collagen-binding heat shock protein 47 and transforming growth factor-beta1 in conjunctival scarring in ocular cicatricial pemphigoid. Invest Ophthalmol Vis Sci, 2003. 44(4): p. 1616-21.
84.Kutz, S.M., C.E. Higgins, R. Samarakoon, S.P. Higgins, R.R. Allen, L. Qi, and P.J. Higgins, TGF-beta 1-induced PAI-1 expression is E box/USF-dependent and requires EGFR signaling. Exp Cell Res, 2006. 312(7): p. 1093-105.
85.Anna, C.H., M. Iida, R.C. Sills, and T.R. Devereux, Expression of potential beta-catenin targets, cyclin D1, c-Jun, c-Myc, E-cadherin, and EGFR in chemically induced hepatocellular neoplasms from B6C3F1 mice. Toxicol Appl Pharmacol, 2003. 190(2): p. 135-45.
86.Lebeau, A., A. Unholzer, G. Amann, M. Kronawitter, I. Bauerfeind, A. Sendelhofert, A. Iff, and U. Lohrs, EGFR, HER-2/neu, cyclin D1, p21 and p53 in correlation to cell proliferation and steroid hormone receptor status in ductal carcinoma in situ of the breast. Breast Cancer Res Treat, 2003. 79(2): p. 187-98.
87.Guh, J.Y., T.D. Chuang, H.C. Chen, W.C. Hung, Y.H. Lai, S.J. Shin, and L.Y. Chuang, Beta-hydroxybutyrate-induced growth inhibition and collagen production in HK-2 cells are dependent on TGF-beta and Smad3. Kidney Int, 2003. 64(6): p. 2041-51.
88.Huang, J.S., L.Y. Chuang, J.Y. Guh, C.J. Chen, Y.L. Yang, T.A. Chiang, M.Y. Hung, and T.N. Liao, Effect of nitric oxide-cGMP-dependent protein kinase activation on advanced glycation end-product-induced proliferation in renal fibroblasts. J Am Soc Nephrol, 2005. 16(8): p. 2318-29.
89.Lee, C.I., J.Y. Guh, H.C. Chen, W.C. Hung, Y.L. Yang, and L.Y. Chuang, Advanced glycation end-product-induced mitogenesis and collagen production are dependent on angiotensin II and connective tissue growth factor in NRK-49F cells. J Cell Biochem, 2005. 95(2): p. 281-92.
90.Lee, C.I., J.Y. Guh, H.C. Chen, K.H. Lin, Y.L. Yang, W.C. Hung, Y.H. Lai, and L.Y. Chuang, Leptin and connective tissue growth factor in advanced glycation end-product-induced effects in NRK-49F cells. J Cell Biochem, 2004. 93(5): p. 940-50.
91.Chen, S.C., J.Y. Guh, H.C. Chen, Y.L. Yang, J.S. Huang, and L.Y. Chuang, Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells. Transl Res, 2007. 149(5): p. 274-81.
92.Guh, J.Y., Y.H. Lai, S.J. Shin, L.Y. Chuang, and J.H. Tsai, Epidermal growth factor in renal hypertrophy in streptozotocin-diabetic rats. Nephron, 1991. 59(4): p. 641-7.
93.Yang, M.L., J.Y. Guh, Y.H. Lai, Y.L. Yang, C.C. Chang, J.H. Tsai, and L.Y. Chuang, Effects of high glucose culture on EGF effects and EGF receptors in the LLC-PK1 cells. Am J Nephrol, 1997. 17(2): p. 193-8.
94.Cooper, M.E., Interaction of metabolic and haemodynamic factors in mediating experimental diabetic nephropathy. Diabetologia, 2001. 44(11): p. 1957-72.
95.Hayashida, T. and H.W. Schnaper, High ambient glucose enhances sensitivity to TGF-beta1 via extracellular signal--regulated kinase and protein kinase Cdelta activities in human mesangial cells. J Am Soc Nephrol, 2004. 15(8): p. 2032-41.
96.Chen, H.C., J.Y. Guh, J.M. Chang, M.C. Hsieh, S.J. Shin, and Y.H. Lai, Role of lipid control in diabetic nephropathy. Kidney Int Suppl, 2005(94): p. S60-2.
97.Thompson, K.L., R. Assoian, and M.R. Rosner, Transforming growth factor-beta increases transcription of the genes encoding the epidermal growth factor receptor and fibronectin in normal rat kidney fibroblasts. J Biol Chem, 1988. 263(36): p. 19519-24.
98.Kizaka-Kondoh, S., N. Akiyama, and H. Okayama, Role of TGF-beta in EGF-induced transformation of NRK cells is sustaining high-level EGF-signaling. FEBS Lett, 2000. 466(1): p. 160-4.
99.Docherty, N.G., O.E. O''Sullivan, D.A. Healy, M. Murphy, J. O''Neill A, J.M. Fitzpatrick, and R.W. Watson, TGF-beta1-induced EMT can occur independently of its proapoptotic effects and is aided by EGF receptor activation. Am J Physiol Renal Physiol, 2006. 290(5): p. F1202-12.
100.Kambhampati, S., G. Ray, K. Sengupta, V.P. Reddy, S.K. Banerjee, and P.J. Van Veldhuizen, Growth factors involved in prostate carcinogenesis. Front Biosci, 2005. 10: p. 1355-67.
101.Agarwal, R., C. Agarwal, H. Ichikawa, R.P. Singh, and B.B. Aggarwal, Anticancer potential of silymarin: from bench to bed side. Anticancer Res, 2006. 26(6B): p. 4457-98.
102.Ishikawa, T., S. Terai, Y. Urata, Y. Marumoto, K. Aoyama, T. Murata, Y. Mizunaga, N. Yamamoto, H. Nishina, K. Shinoda, and I. Sakaida, Administration of fibroblast growth factor 2 in combination with bone marrow transplantation synergistically improves carbon-tetrachloride-induced liver fibrosis in mice. Cell Tissue Res, 2007. 327(3): p. 463-70.
103.Battersby, S., K.J. Sales, A.R. Williams, R.A. Anderson, S. Gardner, and H.N. Jabbour, Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway. Hum Reprod, 2007. 22(1): p. 36-44.
104.Cao, H., N. Dronadula, and G.N. Rao, Thrombin induces expression of FGF-2 via activation of PI3K-Akt-Fra-1 signaling axis leading to DNA synthesis and motility in vascular smooth muscle cells. Am J Physiol Cell Physiol, 2006. 290(1): p. C172-82.
105.Park, S.H., M.J. Choi, I.K. Song, S.Y. Choi, J.O. Nam, C.D. Kim, B.H. Lee, R.W. Park, K.M. Park, Y.J. Kim, I.S. Kim, T.H. Kwon, and Y.L. Kim, Erythropoietin decreases renal fibrosis in mice with ureteral obstruction: role of inhibiting TGF-beta-induced epithelial-to-mesenchymal transition. J Am Soc Nephrol, 2007. 18(5): p. 1497-507.
106.Lin, S.L., R.H. Chen, Y.M. Chen, W.C. Chiang, C.F. Lai, K.D. Wu, and T.J. Tsai, Pentoxifylline attenuates tubulointerstitial fibrosis by blocking Smad3/4-activated transcription and profibrogenic effects of connective tissue growth factor. J Am Soc Nephrol, 2005. 16(9): p. 2702-13.
107.Tokuda, H., K. Kato, Y. Oiso, and O. Kozawa, Contrasting effects of triiodothyronine on heat shock protein 27 induction and vascular endothelial growth factor synthesis stimulated by TGF-beta in osteoblasts. Mol Cell Endocrinol, 2003. 201(1-2): p. 33-8.
108.Oldfield, M.D., L.A. Bach, J.M. Forbes, D. Nikolic-Paterson, A. McRobert, V. Thallas, R.C. Atkins, T. Osicka, G. Jerums, and M.E. Cooper, Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE). J Clin Invest, 2001. 108(12): p. 1853-63.
109.Masszi, A., L. Fan, L. Rosivall, C.A. McCulloch, O.D. Rotstein, I. Mucsi, and A. Kapus, Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelial-to-myofibroblast transition: role for beta-catenin. Am J Pathol, 2004. 165(6): p. 1955-67.
110.Chen, S.J., H. Ning, W. Ishida, S. Sodin-Semrl, S. Takagawa, Y. Mori, and J. Varga, The early-immediate gene EGR-1 is induced by transforming growth factor-beta and mediates stimulation of collagen gene expression. J Biol Chem, 2006. 281(30): p. 21183-97.
111.Wu, Y., X. Zhang, M. Salmon, X. Lin, and Z.E. Zehner, TGFbeta1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members. Biochim Biophys Acta, 2007. 1773(3): p. 427-39.
112.Martin, M.M., J.A. Buckenberger, J. Jiang, G.E. Malana, D.L. Knoell, D.S. Feldman, and T.S. Elton, TGF-{beta}1 Stimulates Human AT1 Receptor Expression in Lung Fibroblasts by Cross-Talk Between the Smad, p38 MAPK, JNK and PI3K Signaling Pathways. Am J Physiol Lung Cell Mol Physiol, 2007.
113.Galliher, A.J. and W.P. Schiemann, Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion. Cancer Res, 2007. 67(8): p. 3752-8.
114.Dong, J., S. Ramachandiran, K. Tikoo, Z. Jia, S.S. Lau, and T.J. Monks, EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1/2 are required for ROS-induced renal cell death. Am J Physiol Renal Physiol, 2004. 287(5): p. F1049-58.
115.Chuang, T.D., J.Y. Guh, S.J. Chiou, H.C. Chen, J.S. Huang, Y.L. Yang, and L.Y. Chuang, Phosphoinositide 3-kinase is required for high glucose-induced hypertrophy and p21WAF1 expression in LLC-PK1 cells. Kidney Int, 2007. 71(9): p. 867-74.
116.Chen, J., J.K. Chen, E.G. Neilson, and R.C. Harris, Role of EGF receptor activation in angiotensin II-induced renal epithelial cell hypertrophy. J Am Soc Nephrol, 2006. 17(6): p. 1615-23.
|