臺灣博碩士論文加值系統

本論文以長時間連續血壓量測為目的，發展出藉由低度壓力的量測方式加壓於手腕上，以偵測脈搏振幅訊號，進而將此訊號導入本研究當中推導出具有血壓動態追蹤功能之低壓轉換公式，實現低壓連續量測系統。
本系統的量測介面由LabVIEW 7.0規劃完成，並搭配National Instruments USB-6009資料擷取卡，做數位輸出以及類比輸入的工作。壓力感測器的輸出信號包括壓脈袋洩壓過程的信號，以及脈搏振盪的信號，這兩種信號必須透過濾波以及放大電路的設計與之分離，分別傳送到兩個類比輸入通道，以進行血壓參數的計算。
經過實際測試的數據分析，本系統證實了使用低度壓力方式，量測連續血壓的可行性，並且實現了具有血壓動態追蹤功能之低壓連續量測系統。未來可以本系統為基礎，加以改進發展出可攜式二十四小時連續血壓監測儀，以提供更多血壓資訊給學術研究以及臨床醫學上使用。

The main propose of the thesis is to acquire the continuous pulse vibration at the patient’s radial artery based on low cuff pressure approach. By introducing the pulse vibration to the low pressure translating formula of dynamic blood pressure tracking capability, continuous blood pressure measurement system based on low cuff pressure approach is achieved.

The interface of the system is completed by LabVIEW 7.0. The digital output and the analog input signals are operated by utilizing National Instruments Data Acquisition (USB-6009) Multifunction I/O Card. There are two kinds of signals at the output of the pressure sensor. They are the signal of cuff pressure and the signal of pulse vibration. A filtering and amplifying circuit is introduced to separate the two signals into two analog input channels of USB-6009. Hence, blood pressure can be calculated after acquiring the data.

According to the experimental results, it proves the feasibility of measuring continuous blood pressure by low pressure approach. Moreover, a continuous blood pressure measurement system based on low cuff pressure approach of dynamic blood pressure tacking capability is achieved. 24-hours portable continuous blood pressure measurement instrument could be developed to provide more information for research and medical uses in the future.

中文摘要
Abstract
誌謝
目錄...i
圖目錄...iv
表目錄...vii
第一章緒論...1
1.1引言...1
1.2研究動機與目的...2
1.3研究方法...3
1.4論文架構說明...4
第二章血壓量測分類與其工作原理...5
2.1侵入式血壓量測...6
2.2非侵入式血壓量測...7
2.2.1聽診法(Asculation Method)...7
2.2.2振盪法(Oscillation Method)...9
2.3非侵入式連續血壓量測...10
2.3.1脈波傳遞時間(Pulse Transit Time)...10
2.3.2脈波傳遞時間與振盪法間歇性校正...12
2.4低壓連續量測...13
2.4.1恆壓低壓法...13
2.4.2具有血壓動態功能之連續血壓量測...16
第三章系統架構與硬體設計...19
3.1壓力感測器...20
3.2濾波放大電路...22
3.3幫浦及洩壓閥控制...25
3.4NI USB-6009資料擷取卡...26
第四章動態追蹤血壓量測方法...28
4.1第一模式(Mode 1)量測流程...29
4.2第二模式(Mode 2)量測流程...34
第五章系統實測與結果討論...36
5.1硬體測試結果...38
5.1.1壓力感測器...38
5.1.2壓脈袋內維持恆壓性能...40
5.2操作介面...43
5.3系統實測結果...46
5.3.1第一模式振盪法實測...47
5.3.2第二模式低壓量測...50
5.4血壓動態追蹤...54
第六章結論與未來展望...59
6.1結論...59
6.2未來展望...61
參考文獻...63
List of Publications...68

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