臺灣博碩士論文加值系統

肥胖症 (obesity) 在獸醫臨床上，常以體態計分法 (body condition score, BCS) 或是形態測定法 (morphometric measurements) 作為貓隻肥胖症的診斷，而人類醫學則以生物電阻抗分析法 (bioelectrical impedance analysis, BIA) 為一常規、簡單且準確的方式來診斷肥胖症。目前發現電阻抗 (impedance, Z) 以及其乘以體重 (body weight, BW) 和身長 (length) 平方處理後所得之ZW/ length2值，皆會與體脂肪含量成正比。為開發適用於獸醫臨床上，測量貓隻體脂肪的BIA系統，本研究測量24隻健康貓隻之BCS，以形態測定法計算體脂肪含量，並比較不同意識狀態、姿勢以及電極位置下所測得之電阻抗值。再以相關係數分析找出電阻抗值以及ZW/ length2值分別與體脂肪含量間的相關性，並以線性迴歸分析建立BIA對體脂肪預測公式。最後以統計學方式將電阻抗值以及ZW/ length2值信賴區間5 - 95 % 的數值建立為參考值 (reference value)。本研究結果發現， BIA測定時會受意識以及姿勢不同所影響，而不同電極位置則不會影響。而相關系數分析的結果指出，電阻抗值能作為體脂肪含量百分比 (%BF) 的預測，ZW/ length2值能作為 %BF以及體脂肪值量組織 (BF) 的預測。BIA於臨床使用上，建議貓隻於清醒狀態下，呈現站立的姿勢，電極位置於同側，進行電阻抗值的測量，配合公式：BF = 1.4265 × ZW/length2 + 0.2473，可以有效測量出體脂肪含量；而此狀態之電阻抗正常參考值為168.67至365.59 Ω，ZW/ length2值之正常參考值為0.290至0.790 ΩKg/cm2，低於此正常值貓隻視為體脂肪含量不足，高於者視為含有過多的體脂肪。

目次
中文摘要 ……………………………………………………………i
英文摘要 ……………………………………………………………ii
目次 …………………………………………………………………v
表次 …………………………………………………………………vii
圖次 ……………………………………………………………………ix
第一章 緒論………………………………………………………… 1
第二章 文獻探討……………………………………………………4
第一節 肥胖症簡介………………………………………………4
第二節 肥胖症的診斷方式…………………………………… 10
第三節 生物電阻抗分析法之發展…………………………… 17
第四節 生物電阻抗分析法之原理……………………………18
第五節 生物電阻抗分析法在動物上的應用……………………20
第三章 材料與方法…………………………………………………22
第一節 研究問題與研究假設……………………………………22
第二節 研究設計…………………………………………… 23
第三節 研究對象…………………………………………………25
第四節 誘導及維持麻醉…………………………………………25
第五節 體態計分法………………………………………………26
第六節 形態測定法………………………………………………27
第七節 生物電阻抗分析法………………………………………28
第八節 資料整理與統計分析………………………………………30
第四章 研究結果……………………………………………………32
第一節 體態計分法測定結果……………………………………32
第二節 形態測定法測量結果……………………………………32
第三節 生物電阻抗法測量結果…………………………………33
第四節 ZW/length2值的計算結果………………………………34
第五節 相關係數與線性迴歸分析………………………………35
第六節 參考值之建立……………………………………………37
第五章 討論…………………………………………………………39
第一節 肥胖症臨床診斷方式比較………………………………39
第二節 不同狀況下測量所得之電阻抗值之比較………………40
第三節 電阻抗值與體脂肪含量的關係…………………………42
第四節 ZW/length2值與體脂肪含量的關係……………………43
第五節 生物電阻抗分析法作為體脂肪含量的測定……………44
第六節 生物電阻抗分析法之參考值…………………… 47
第六章 結論…………………………………………………………49
參考文獻……………………………………………………………51

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