跳到主要內容

臺灣博碩士論文加值系統

(3.236.23.193) 您好!臺灣時間:2021/07/24 12:23
字體大小: 字級放大   字級縮小   預設字形  
回查詢結果 :::

詳目顯示

我願授權國圖
: 
twitterline
研究生:郭睿宜
研究生(外文):Jui-yi Kuo
論文名稱:使用磁振相位對比影像針對矯正後法洛氏四重症之肺動脈血流其逆流與紊流之評估
論文名稱(外文):Evaluation of regurgitation and turbulence of flow in pulmonary arteries after repair of tetralogy of Fallot using phased-contrast MR imaging.
指導教授:柯正雯吳銘庭吳銘庭引用關係
指導教授(外文):Cheng-Wen KoMing-ting Wu
學位類別:碩士
校院名稱:國立中山大學
系所名稱:資訊工程學系研究所
學門:工程學門
學類:電資工程學類
論文種類:學術論文
論文出版年:2007
畢業學年度:95
語文別:英文
論文頁數:52
中文關鍵詞:法洛氏四重症磁振造影相位對比影像肺動脈
外文關鍵詞:Magnetic Resonance ImagingPulmonary ArteriesTetralogy of FallotPhase Contrast MR Imaging
相關次數:
  • 被引用被引用:0
  • 點閱點閱:167
  • 評分評分:
  • 下載下載:0
  • 收藏至我的研究室書目清單書目收藏:0
磁振影像(Magnetic Resonance Imaging, 簡稱MRI) 提供臨床上非侵入式的應用。法洛式四重症患者的心臟有四種主要的缺陷。在接受臨床手術後,患者的心臟仍不能提供和正常人一樣足夠的血流量。在本研究中,我們使用向位對比影像替矯正後患者的肺動脈做血流逆流和紊流評估,並使用參數coefficient of variance (CV), regurgitant fraction (RF), normalized area variation (NAV)分析患者和正常人的差異。結果顯示CV和regurgitant fraction相關性並不緊密。本篇研究也能許幫助醫生做臨床上的診斷。

我們也使用另外三個參數比較正常人和患者的差異。我們使用windkessel volume討論進血流和出血流的差值。使用pulse wave velocity (PWV)分析壓力波傳遞速度。使用pulmonary vascular resistance (PVR)分析血管壁阻力。雖然PWV和PVR因為於心臟週期內取點數的不足導致資訊的喪失,但研究的結果也可做為參考之用。
Magnetic resonance imaging nowadays supplies a noninvasive method in clinical applications. For tetralogy of Fallot (TOF) patients, after undergoing clinical operation, their cardiac anatomy still cannot supply sufficient blood flow in the pulmonary arteries with respect to the normal. In this study, we use phase contrast MR imaging to evaluate of regurgitation and turbulence of flow in pulmonary arteries after repair of TOF. We use parameters such as coefficient of variance (CV), regurgitant fraction (RF), and normalized area variation (NAV) to analyze the difference between repaired patients and normal controls. Our result also shows that CV and regurgitant fraction have loose relation. This study may provide more information to help doctors in clinical diagnosis.

In the meanwhile, another three parameters were used to evaluate patients and normal persons. We use windkessel volume to see the difference of flow volume between inlet and outlet in the pulmonary arteries. We use pulse wave velocity (PWV) to discuss the propagating velocity of pressure wave on the vascular wall. We use pulmonary vascular resistance (PVR) to analyze the resistance of blood wall. PWV and PVR may lose information by means of insufficient points in a cardiac cycle, but the result may still be a kind of reference.
Chapter 1 Introduction
1.1 Background
1.1.1 Magnetic Resonance Imaging
1.1.2 Phase Contrast Imaging
1.1.3 Tetralogy of Fallot (TOF)
1.2 Literature
1.2.1 Fontan
1.2.2 Regurgitant Fraction
1.2.3 Windkessel volume
1.2.4 Pulse Wave Velocity (PWV)
1.2.5 Pulmonary Vascular Resistance (PVR)
1.3 Motivation
1.4 Synopsis
Chapter 2 Materials and Methods
2.1 PC MR images
2.2 data pre-processing
2.2.1 ROI
2.2.2 vector projection
2.3 analysis parameters
2.3.1 CV
2.3.2 Net Flow
2.3.3 Regurgitant Fraction
2.3.4 Normalized Area Variation
2.3.5 Windkessel Volume
2.3.6 Pulse Wave Velocity (PWV)
2.3.7 Pulse Vascular Resistance (PVR)
Chapter 3 Results
3.1 Subjects
3.2 CV
3.3 Regurgitant Fraction
3.4 Normalized Area Variation
3.5 Correlation between CV-mean and RF
3.6 Correlation between Net Flow and CV
3.7 Correlation between NAV and RF
3.8 Correlation between NAV and CV-mean
3.9 Windkessel Volume
3.10 Pulse Wave Velocity (PWV)
3.11 Pulmonary Vascular Resistance (PVR)
Chapter 4 Discussion and Conclusions
4.1 Discussion
4.2 Conclusions
References
[1] Cornelius von Morze, D. X., Derk D. Purcell, Christopher P. Hess, Pratik Mukherjee, David Saloner, Douglas A.C. Kelley, Daniel B. Vigneron (2007). Intracranial Time-of-Flight MR Angiography at 7T with Comparison to 3T. ISMRM-ESMRMB. Berlin.

[2] Scott A. Mirowitz, M., Fernando R. Gutierrez, MD, Charles E. Canter, MD, Michael W. Vannier, MD (1989). "Tetralogy of Fallot: MR findings." Radiology 171: 207-212.

[3] Bushong, S. C. (2003). Magnetic Resonance Imaging: Physical and Biological Principles, Mosby.

[4] I-Seok Kang, M.D., Andrew N. Redington, M.D., Leland N. Benson, M.D., Christopher Macgowan, PhD, Emanuela R. Valsangiacomo, M.D., Kevin Roman, M. D.,Christian J. Kellenberger, M.D., Shi-Joon Yoo, M.D. (2003). "Differential Regurgitation in Branch Pulmonary Arteries After Repair of Tetralogy of Fallot: A Phase-Contrast Cine Magnetic Resonance Study." Circulation 107: 2938-2943.

[5] Joachim Lotz, M. D., Christian Meier, Ph. D., Andreas Leppert, M. D., Michael Galanski, M. D. (2002). "Cardiovascular Flow Measurement with Phase-Contrast MR Imaging: Basic Facts and Implementation." RadioGraphics 22: 651-671.

[6] Peng, H.-H. (2003). Estimation of Pulse Wave Velocity in Main Pulmonary Artery with Phase Contrast Imaging. Taipei, National Taiwan University. Master Dissertation.

[7] Karen I. Norton, M. D., Carrie Tong, M.D., Ronald B. J. Glass, M.D., James C. Nielsen, M.D. (2006). "Cardiac MR Imaging Assessment Following Tetralogy of Fallot Repair." RadioGraphics 26: 197-211.

[8] http://www.nhlbi.nih.gov/health/dci/Diseases/tof/tof_what.html

[9] Joseph G. Murphy, B. J. G., Douglas D. Mair, Valentin Fuster, Michael D. McGoon, Duane M. Ilstrup, Dwight C. McGoon, John W. Kirklin, and Gordon K. Danielson (1993). "Long-Term Outcome in Patients Undergoing Surgical Repair of Tetralogy of Fallot." N Engl J Med. 329: 593-599.

[10] Joseph Caspi, M. D., Eli Zalstein, M.D., Nili Zucker, M.D., Azi Applebaum, M.D., Lynn H. Harrison, Jr, M.D., Nabil A. Munfakh, M.D., Herman A. Heck, Jr, M.D., T. Bruce Ferguson, Jr, M.D., Aluizio Stopa, M.D., Michael White, M.D., Ph.D., Eudice E. Fontenot, M.D. (1999). "Surgical Management of Tetralogy of Fallot in the First Year of Life." Ann Thorac Surg 68: 1344-1348.

[11] Frank A. Pigula, P. N. K., John E. Mayer, Pedro J. del Nido and Richard A. Jonas (1999). "Repair of Tetralogy of Fallot in Neonates and Young Infants." Circulation 100: 157-161.

[12] http://www.bristol-inquiry.org.uk/final_report/annex_a/chapter_3_23.htm

[13] http://heart.health.ivillage.com/congenitalheartdisease/tetralogyoffallot5.cfm

[14] Eliezer Be''eri, M. D., Stephan E. Maier, M.D., Ph.D.; Michael J. Landzberg, M.D., Taylor Chung, M.D.; Tal Geva, M.D. (1998). "In Vivo Evaluation of Fontan Pathway Flow Dynamics by Multidimensional Phase-Velocity Magnetic Resonance Imaging." Circulation 98: 2873-2882.

[15] Jiun-Jr Wang, A. B. O. B., Nigel G. Shrive, Kim H. Parker, and John V. Tyberg (2003). "Time-domain representation of ventricular-arterial coupling as a windkessel and wave system." Am J Physiol Heart Circ Physiol 284: H1358-H1368.

[16] H-H. Peng, H.-Y. Y., H-W. Chung, W-Y. I. Tseng (2004). Estimation of pulmonary windkessel volume in patients with pulmonary hypertension using MR phase contrast imaging. ISMRM. Kyoto.

[17] Raad H. Mohiaddin, G. Z. Y., Philip J. Kilner (1994). "Visualization of Flow by Vector Analysis of Multidirectional Cine MR Velocity Mapping." J Comput Assist Tomogr 18: 383-392.

[18] Serge Vullie´moz, N. S., Reto Meuli (2002). "Estimation of Local Aortic Elastic Properties With MRI." Magnetic Resonance in Medicine 47: 649-654.

[19] Hsu-Hsia Peng, M. S., Hsiao-Wen Chung, Ph.D., His-Yu Yu, M.D., Wen-Yih I. Tseng, M.D., Ph.D. (2006). "Estimation of Pulse Wave Velocity in Main Pulmonary Artery With Phase Contrast MRI: Preliminary Investigation." Magnetic Resonance Imaging 24: 1303-1310.

[20] Elie Mousseaux, M. D., Ph.D., Jean Pierre Tasu, M.D., Ph.D., Odile Jolivet, Ph.D., Ge´rard Simonneau, M.D., Jacques Bittoun, M.D., Ph.D., Jean-Claude Gaux, M.D. (1999). "Pulmonary Arterial Resistance: Noninvasive Measurement with Indexes of Pulmonary Flow Estimated at Velocity-encoded MR Imaging-Preliminary Experience." Radiology 212: 896-902.

[21] Niu, S.-C. (2006). The quantitative analysis of in-plane flow speed in branch pulmonary arteries after repair of tetralogy of Fallot: A phase-contrast MR imaging study. Kaohsiung, National Sun Yat-sen University. Master Dissertation.

[22] Niu, S.-C. (2006). Comparison of regurgitation and variation of in-plane flow speed in branch pulmonary arteries after repair of tetralogy of Fallot: A phase-contrast MR imaging study. ISMRM. Seattle.

[23] PATRICK TURSKI, M. D. "SIGNA Application Guild: Vascular Magnetic Resonance Imaging." Second Edition.

[24] HAST, J. (2003). Self-mixing interferometry and its applications in noninvasive pulse detection, University of Oulu. Ph Dissertation.

[25] Valérie Marque; Pascal Kieffer, J. A., Isabelle Lartaud-Idjouadiene (1999). "Elastic Properties and Composition of the Aortic Wall in Old Spontaneously Hypertensive Rats." Hypertension 34: 415-422.

[26] Bruce R. Munson, D. F. Y., Theodore H. Okiishi (2002). Fundamentals of Fluid Mechanics, John Wiley & Sons, Inc.
QRCODE
 
 
 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                               
第一頁 上一頁 下一頁 最後一頁 top
無相關期刊