本研究旨在探討台灣地區老人代謝症候群組成因子與心血管疾病之間的相關性，以「第二次國民營養健康狀況變遷調查（NAHSIT Ⅱ）」為資料庫來源，排除無其他相關健康篩檢資料者後計1,543名(男性790人、女性753人)之65歲以上老年人為研究對象，進行斷面調查資料之分析。代謝症候群依定義之不同，分為代謝症候群Ⅰ及代謝症候群Ⅱ來探討檢視，代謝症候群Ⅰ依據美國國家膽固醇教育計劃（NECP ATP Ⅲ）之定義，代謝症候群Ⅱ依據國際糖尿病基金會(IDF) 之定義。
研究結果顯示：本研究樣本之心血管疾病盛行率為21.6％(其中女性佔11.6％、男性10.0％)，女性心血管疾病盛行率高於男性(p <.05)；代謝症候群Ⅰ之盛行率高達47.3％(其中女性佔26.1％、男性21.2％)，女性代謝症候群Ⅰ盛行率亦高於男性(p <.001)；代謝症候群Ⅱ之盛行率為32.1％(其中女性佔20.2％、男性11.9％)，女性代謝症候群Ⅱ盛行率亦是高於男性(p <.001)。在控制其他變項後，女性相對於男性，發生心血管疾病之危險性較大（p <.01）；75-79歲者相對於65-69歲者，發生心血管疾病之危險性也較大（p <.01）；有接受教育者相對於無接受教育者，發生心血管疾病之危險性較大（p <.01）；高密度脂蛋白膽固醇（HDL-C）數值較低者相對HDL-C數值高者，發生心血管疾病之危險性較大（p <.05）；有代謝症候群Ⅰ者相對於無代謝症候群Ⅰ者，發生心血管疾病之危險性亦較大（p <.05）。
結論：本研究探討代謝症候群組成因子與心血管疾病相關性，結果顯示代謝症候群與心血管疾病是存有高度相關之危險性，部分統計則顯示兩者間之關係，其明顯性並非一致。

The purpose of this study is to explore the relationship between cardiovascular disease and metabolic syndrome in the elders in Taiwan. This study design was cross-sectional and utilized database of Nutrition and Health Survey in Taiwan II (NAHSIT II) for analysis. We collected 1,543 elderly (790 men,753 women) aged 65 y/o and above. Those who did not have relevant data in health screening were excluded. The definition of metabolic syndrome type I was defined by the NCEP ATP Ⅲ criteria, and metabolic syndrome type II was defined by the IDF criteria.
The results showed that the prevalence of cardiovascular disease in our sample is 21.6 %, and amongst 11.6 % in females, and 10.0 % in males. The prevalence of cardiovascular disease is higher in female than in male (p<0.05). The prevalence of metabolic syndrome type 1 in general are 47.3 %, and 26.1 % for females, and 21.2 % for males respectively；and it is higher in females than in males (p<0.001). The prevalence of metabolic syndrome type II in general are 32.1%, and 20.2 % for females, 11.9 % for males respectively. It is also higher in females than in males (p<0.001). In univariant analysis, the higher risks in the incidence of cardiovascular disease included : female v.s. male (p<0.01), 75-79 y/o v.s. 65-69 y/o (p<0.01), educated v.s. uneducated (p<0.01), low HDL-C value v.s. high HDL-C value (p<0.05), and metabolic syndrome type I v.s. non-metabolic syndrome type I (p<0.05).
In conclusion, this study was to explore the relationship between the components of metabolic syndrome and cardiovascular disease. The results showed that those risk factors were associated highly between metabolic syndrome and cardiovascular disease. However, the significance was not uniformly evident.

目 錄
誌 謝………………………………………………………………………………Ⅰ
中文摘要……………………………………………………………………………Ⅱ
英文摘要……………………………………………………………………………Ⅲ
圖表索引……………………………………………………………………………Ⅳ
第一章 續論………………………………………………………………………1
第一節 研究背景及研究動機……………………………………………………1
第二節 研究的重要性……………………………………………………………4
第三節 研究目的…………………………………………………………………5
第二章 文獻查證…………………………………………………………………7
第一節 心血管疾病的定義及盛行率……………………………………………7
第二節 代謝症候群的歷史沿革、定義及盛行率………………………………10
第三節 影響心血管疾病之因子…………………………………………………15
第四節 代謝症候群及心血管疾病之相關研究…………………………………19
第三章 研究方法學………………………………………………………………22
第一節 研究架構…………………………………………………………………22
第二節 名詞解釋…………………………………………………………………25
第三節 研究對象…………………………………………………………………27
第四節 研究工具…………………………………………………………………27
第五節 資料處理與分析的方法…………………………………………………29
第四章 研究結果…………………………………………………………………31
第一節 基本資料分佈……………………………………………………………31
第二節 不同性別發生心血管疾病及代謝症候群之情形………………………33
第三節 男性發生心血管疾病及心血管疾病危險因子之單變項分析…………34
第四節 女性發生心血管疾病與心血管疾病危險因子之單變項分析…………36
第五節 代謝症候群及其個別組成因子與心血管疾病之多變項分析…………37
第五章 討論………………………………………………………………………45
第一節 心血管疾病及心血管疾病危險因子之相關性…………………………45
第二節 代謝症候群及其個別組成因子與心血管疾病之相關性………………48
第三節 研究限制…………………………………………………………………50
第六章 結論與展望………………………………………………………………51
第七章 參考文獻…………………………………………………………………74
中文部分 ………………………………………………………………………74
英文部分 ………………………………………………………………………75

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