臺灣博碩士論文加值系統

根據衛生署公佈的統計資料顯示，民國95年國人十大死因中，糖尿病在男性人口中為第四順位，女性人口中則為第三順位，可見糖尿病威脅台灣的人口之嚴重性。65歲以上的人幾乎每五個人就有一個是糖尿病患，更突顯問題之廣泛性。根據官方統計資料，有四到七成下肢截肢的病患與糖尿病有關；糖尿病的足部感染問題，是糖尿病患者最常見也最容易被忽視的併發症；其中有八成五的糖尿病患常常因而面臨必須截肢的命運。所以本研究擬建立一套人體手足末端血管紅外線影像擷取與量化分析系統，透過本系統可以輔助臨床醫師做血管影像之擷取、分析與個人資料庫之建立，方便觀察與長期追蹤；醫師亦可以透過血管影像之量化參數如不變矩、碎形維度及血管徑比率做為輔助臨床診斷之依據，以期達到「早期診斷、早期治療」的目的。

According to the reports from the Department of Health, the Executive Yuan, Taiwan, 2006, the mortality associated with diabetes are ranked the fourth in male and the third in female among the leading causes of mortality in Taiwan. The diabetes have become a very important health issue in Taiwan. One out of five the population aged over 65 are the patients with diabetes. There are 40% to 70% of the lower limb amputation patients associated with diabetes. The infection of diabetic foot has become an important clinical issue. How to develop an infrared system to quantify the blood vessel of diabetic foot is crucial reference for clinical amputation. Therefore, this thesis we try to establish a portable image acquisition system to quantify the parameters such as invariant moments, fractal dimension and ratio of blood vessel on diabetic extremity. The developed parameters of blood vessel image can provide a useful tool for clinical diagnosis. The earlier detection and earlier treatment has become an important clinical issue.

摘要 iv
英文摘要 v
致謝 vi
目次 vii
表目錄 viii
圖目錄 xi
第一章 緒論 1
1-1 研究動機 1
1-2 研究目的 2
1-3背景及文獻回顧 3
1-3-1人體的血管架構 3
1-3-2紅外線之簡介 6
1-3-3血管之紅外線影像 7
1-3-4文獻回顧 10
第二章 硬體架構與設備 13
2-1 系統架構 13
2-2 紅外線影像擷取系統 15
2-3 硬體系統校正 17
第三章 量化分析方法 20
3-1 研究流程 20
3-2 量化分析系統 20
3-2-1 影像前處理 21
3-2-2 不變矩 27
3-2-3 量化特徵參數 30
3-2-3-1 碎形維度 30
3-2-3-2 血管徑比率 34
3-3 使用者介面 37
第四章 結果與討論 40
4-1系統校正結果 40
4-1-1 光學系統校正 40
4-1-2 假體驗證 42
4-2人體手足末端血管影像 46
4-2-1 手指血管紅外線影像 46
4-2-2 腳趾血管紅外線影像 46
4-3量化參數分析 47
4-3-1 不變矩 47
4-3-2 碎形維度 48
4-3-3 血管徑比率 50
第五章 結論與未來研究方向 52
5-1 結論 52
5-2 未來研究方向 52
參考文獻 53

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