|
Anderson, R.J. (2007). Kidney in sepsis. Crit. Care Med. 35, 2223-2224. Baud, L., Oudinet, J.P., Bens, M., Noe, L., Peraldi, M.N., Rondeau, E., Etienne, J., and Ardaillou, R. (1989). Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide. Kidney Int. 35, 1111-1118. Beaulieu, J.M., Marion, S., Rodriguiz, R.M., Medvedev, I.O., Sotnikova, T.D., Ghisi, V., Wetsel, W.C., Lefkowitz, R.J., Gainetdinov, R.R., and Caron, M.G. (2008). A -arrestin 2 signaling complex mediates lithium action on behavior. Cell 132, 125-136. Beaulieu, J.M., Sotnikova, T.D., Yao, W.D., Kockertiz, L., Woodgett, J.R., Gainetdinov, R.R., and Caron, M.G. (2004). Lithium antagonizes dopamine-dependent behaviors mediated by an Akt/glycogen synthase kinase 3 signaling cascade. Proc. Natl. Acad. Sci. 101, 5099-5104. Bhat, R.V., Leonov, S., Luthman, J., Scott, C.W., and Lee, C.M. (2002). Interactions between GSK3beta and caspase signalling pathways during NGF deprivation induced cell death. J. Alzheimers Dis. 4, 291-301. Bijur, G.N., De Sarno, P., and Jope, R.S. (2000). Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium. J. Biol. Chem. 275, 7583-7590. Cohen, P., and Frame, S. (2001). The renaissance of GSK-3. Nat. Rev. Mol. Cell Biol. 2, 769-776. Cross, D.A., Alessi, D.R., Cohen, P., Andjelkovich, M., and Hemmings, B.A. (1995). Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378, 785-789. Cunningham, P.N., Dyanov, H.M., Park, P., Wang, J., Newell, K.A., and Quigg, R.J. (2002). Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney. J. Immunol. 168, 5817-5823. Cunningham, P.N., Wang, Y., Guo, R., He, G., and Quigg, R.J. (2004). Role of Toll-like receptor 4 in endotoxin-induced acute renal failure. J. Immunol. 172, 2629-2635. Cuzzocrea, S., Malleo, G., Genovese, T., Mazzon, E., Esposito, E., Muia, C., Abdelrahman, M., Di Paola, R., and Thiemermann, C. (2007a). Effects of glycogen synthase kinase-3beta inhibition on the development of cerulein-induced acute pancreatitis in mice. Crit. Care Med 35, 2811-2821. Cuzzocrea, S., Mazzon, E., Di Paola, R., Muia, C., Crisafulli, C., Dugo, L., Collin, M., Britti, D., Caputi, A.P., and Thiemermann, C. (2006). Glycogen synthase kinase-3beta inhibition attenuates the degree of arthritis caused by type II collagen in the mouse. Clin. Immunol. 120, 57-67. Cuzzocrea, S., Mazzon, E., Esposito, E., Muia, C., Abdelrahman, M., Di Paola, R., Crisafulli, C., Bramanti, P., and Thiemermann, C. (2007b). Glycogen synthase kinase-3beta inhibition attenuates the development of ischaemia/reperfusion injury of the gut. Intensive Care Med. 33, 880-893. de Visser, K.E., Eichten, A., and Coussens, L.M. (2006). Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 6, 24-37. Deng, J., Kohda, Y., Chiao, H., Wang, Y., Hu, X., Hewitt, S.M., Miyaji, T., McLeroy, P., Nibhanupudy, B., Li, S., et al. (2001). Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury. Kidney Int. 60, 2118-2128. Dugo, L., Abdelrahman, M., Murch, O., Mazzon, E., Cuzzocrea, S., and Thiemermann, C. (2006a). Glycogen synthase kinase-3beta inhibitors protect against the organ injury and dysfunction caused by hemorrhage and resuscitation. Shock 25, 485-491. Dugo, L., Collin, M., Allen, D.A., Murch, O., Foster, S.J., Yaqoob, M.M., and Thiemermann, C. (2006b). Insulin reduces the multiple organ injury and dysfunction caused by coadministration of lipopolysaccharide and peptidoglycan independently of blood glucose: role of glycogen synthase kinase-3beta inhibition. Crit. Care Med 34, 1489-1496. Dugo, L., Collin, M., Allen, D.A., Patel, N.S., Bauer, I., Mervaala, E., Louhelainen, M., Foster, S.J., Yaqoob, M.M., and Thiemermann, C. (2007a). Inhibiting glycogen synthase kinase 3beta in sepsis. Novartis Found. Symp. 280, 128-142; discussion 142-146, 160-164. Dugo, L., Collin, M., Allen, D.A., Patel, N.S., Bauer, I., Mervaala, E.M., Louhelainen, M., Foster, S.J., Yaqoob, M.M., and Thiemermann, C. (2005). GSK-3beta inhibitors attenuate the organ injury/dysfunction caused by endotoxemia in the rat. Crit. Care Med. 33, 1903-1912. Dugo, L., Collin, M., and Thiemermann, C. (2007b). Glycogen synthase kinase 3beta as a target for the therapy of shock and inflammation. Shock 27, 113-123. Endo, H., Nito, C., Kamada, H., Nishi, T., and Chen, P.H. (2006). Activation of the Akt/GSK3beta signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 26, 1479-1489. Frame, S., and Cohen, P. (2001). GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359, 1-16. Giannopoulou, M., Dai, C., Tan, X., Wen, X., Michalopoulos, G.K., and Liu, Y. (2008). Hepatocyte growth factor exerts its anti-inflammatory action by disrupting nuclear factor-B signaling. Am. J. Pathol. 173, 30-41. Gong, R., Rifai, A., and Dworkin, L.D. (2005). Activation of PI3K-Akt-GSK3beta pathway mediates hepatocyte growth factor inhibition of RANTES expression in renal tubular epithelial cells. Biochem. Biophys. Res. Commun. 330, 27-33. Gong, R., Rifai, A., and Dworkin, L.D. (2006a). Anti-inflammatory effect of hepatocyte growth factor in chronic kidney disease: targeting the inflamed vascular endothelium. J. Am. Soc. Nephrol. 17, 2464-2473. Gong, R., Rifai, A., and Dworkin, L.D. (2006b). Hepatocyte growth factor suppresses acute renal inflammation by inhibition of endothelial E-selectin. Kidney Int. 69, 1166-1174. Gong, R., Rifai, A., Ge, Y., Chen, S., and Dworkin, L.D. (2008). Hepatocyte growth factor suppresses proinflammatory NFkappaB activation through GSK3beta inactivation in renal tubular epithelial cells. J. Biol. Chem 283, 7401-7410. Guo, R., Wang, Y., Minto, A.W., Quigg, R.J., and Cunningham, P.N. (2004). Acute renal failure in endotoxemia is dependent on caspase activation. J. Am. Soc. Nephrol. 15, 3093-3102. Gupta, A., Berg, D.T., Gerlitz, B., Sharma, G.R., Syed, S., Richardson, M.A., Sandusky, G., Heuer, J.G., Galbreath, E.J., and Grinnell, B.W. (2007). Role of protein C in renal dysfunction after polymicrobial sepsis. J. Am. Soc. Nephrol. 18, 860-867. Henriksen, E.J. and Dokken, B.B. (2006). Role of glycogne synthase kinase-3 in insulin resisitance and type 2 diabetes. Curr. Drug Targets 7, 1435-1441. Hetman, M., Cavanaugh, J.E., Kimelman, D., and Xia, Z. (2000). Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal. J. Neurosci. 20, 2567-2574. Hetman, M., Hsuan, S.L., Habas, A., Higgins, M.J., and Xia, Z. (2002). ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. J. Bio. Chem. 277, 49577-49584. Hoeflich, K.P., Luo, J., Rubie, E.A., Tsao, M.S., Jin, O., and Woodgett, J.R. (2000). Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 406, 86-90. Hongisto, V., Smeds, N., Brecht, S., Herdegen, T., Courtney, M.J., and Coffey, E.T. (2003). Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3. Mol. Cell. Biol. 23, 6027-6036. Hooper, C., Killick, R., and Lovestone, S. (2008). The GSK3 hypothesis of Alzheimer's disease. J. Neurochem. 104, 1433-1439. Hotchkiss, R.S., and Karl, I.E. (2003). The pathophysiology and treatment of sepsis. N. Engl J. Med. 348, 138-150. Huang, H.C., and Klein, P.S. (2006). Multiple roles for glycogen synthase kinase-3 as a drug target in Alzheimer's disease. Curr. Drug Targets 7, 1389-1397. Ivaska, J., Nissinen, L., Immonen, N., Erikson, J.E., Kähäri, V.M., and Heino, J. (2002). Integrin alpha2beta1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta. Mol. Cell. Biol. 22, 1352-1359. Jo, S.K., Cha, D.R., Cho, W.Y., Kim, H.K., Chang, K.H., Yun, S.Y., and Won, N.H. (2002). Inflammatory cytokines and lipopolysaccharide induce Fas-mediated apoptosis in renal tubular cells. Nephron 91, 406-415. Jope, R.S., and Bijur, G.N. (2002). Mood stabilizers, glycogen synthase kinase-3beta and cell survival. Mol. Psychiatry 7 Suppl 1, S35-45. Jope, R.S., and Johnson, G.V. (2004). The glamour and gloom of glycogen synthase kinase-3. Trends Biochem. Sci. 29, 95-102. Jope, R.S., Yuskaitis, C.J., and Beurel, E. (2007). Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem. Res. 32, 577-595. Khan, R.Z., and Badr, K.F. (1999). Endotoxin and renal function: perspectives to the understanding of septic acute renal failure and toxic shock. Nephrol. Dial. Transplant. 14, 814-818. King, T.D., Bijur, G.N., and Jope, R.S. (2001). Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium. Brain Res. 919, 106-114. Klover, P.J., Zimmers, T.A., Koniaris, L.G., and Mooney, R.A. (2003). Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice. Diabetes 52, 2784-2789. Knotek, M., Rogachev, B., Wang, W., Ecder, T., Melnikov, V., Gengaro, P.E., Esson, M., Edelstein, C.L., Dinarello, C.A., and Schrier, R.W. (2001). Endotoxemic renal failure in mice: Role of tumor necrosis factor independent of inducible nitric oxide synthase. Kidney Int. 59, 2243-2249. Koide, N., Narita, K., Kato, Y., Sugiyama, T., Chakravortty, D., Morikawa, A., Yoshida, T., and Yokochi, T. (1999). Expression of Fas and Fas ligand on mouse renal tubular epithelial cells in the generalized shwartzman reaction and its relationship to apoptosis. Infect. and Immun. 67, 4112-4118. Li, X., Bijur, G.N., and Jope, R.S. (2002). Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection. Bipolar Disord. 4, 137-144. Lin, C.F., Chen, C.L., Chiang, C.W., Jan, M.S., Huang, W.C., and Lin, Y.S. (2007). Glycogen synthase kinase-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis. J. Cell Sci. 120, 2935-2943. Loberg, R.D., Vesely, E., and Brosius, F.C., 3rd (2002). Enhanced glycogen synthase kinase-3beta activity mediates hypoxia-induced apoptosis of vascular smooth muscle cells and is prevented by glucose transport and metabolism. J. Biol. Chem. 277, 41667-41673. Loisa, P., Rinne, T., Laine, S., Hurme, M., and Kaukinen, S. (2003). Anti-inflammatory cytokine response and the development of multiple organ failure in severe sepsis. Acta. Anaesth. Scand. 47, 319-325. Marshall, J.C., Vincent, J.L., Fink, M.P., Cook, D.J., Rubenfeld, G., Foster, D., Fisher, C.J., Jr., Faist, E., and Reinhart, K. (2003). Measures, markers, and mediators: toward a staging system for clinical sepsis. A report of the Fifth Toronto Sepsis Roundtable, Toronto, Ontario, Canada, October 25-26, 2000. Crit. Care Med. 31, 1560-1567. Martin, G.S., Mannino, D.M., Eaton, S., and Moss, M. (2003). The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med. 348, 1546-1554. Martin, M., Rehani, K., Jope, R.S., and Michalek, S.M. (2005). Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nat. Immunol. 6, 777-784. Martinez, A., Alonso, M., Castro, A., Perez, C., and Moreno, F.J. (2002). First non-ATP competitive glycogen synthase kinase 3 (GSK-3) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer’s disease. J. Med. Chem. 45, 1292-1299. Matsuoka, Y., Picciano, M., Malester, B., LaFrancois, J., Zehr, C., Daeschner, J.M., Olschowka, J.A., Fonseca, M.I., O'Banion, M.K., Tenner, A.J., et al. (2001). Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease. Am. J. Pathol. 158, 1345-1354. Messmer, U.K., Briner, V.A., and Pfeilschifter, J. (1999). Tumor necrosis factor-alpha and lipopolysaccharide induce apoptotic cell death in bovine glomerular endothelial cells. Kidney Int. 55, 2322-2337. Moore, K.W., de Waal Malefyt, R., Coffman, R.L., and O'Garra, A. (2001). Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19, 683-765. Nadiri, A., Wolinski, M.K., and Saleh, M. (2006). The inflammatory caspase: key players in the host response to pathogenic invasion and sepsis. J. Immunol. 177, 4239-4245. Neveu, H., Kleinknecht, D., Brivet, F., Loirat, P., and Landais, P. (1996). Prognostic factors in acute renal failure due to sepsis. Results of a prospective multicentre study. The French Study Group on Acute Renal Failure. Nephrol. Dial. Transplant. 11, 293-299. Obligado, S.H., Ibraghimov-Beskrovnaya, O., Zuk, A., Meijer, L., and Nelson, P.J. (2008). CDK/GSK-3 inhibitors as therapeutic agents for parenchymal renal diseases. Kidney Int. 73, 684-690. O'Farrell, A.M., Liu, Y., Moore, K.W., and Mui, A.L. (1998). IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J. 17, 1006-1018. Ortiz A, Justo P, Sanz A, Lorz C, and Egido J. (2003). Targeting apoptosis in acute tubular injury. Biochem. Pharmacol. 66, 1589-1594. Ortiz-Arduan, A., Danoff, T.M., Kalluri, R., Gonzalez-Cuadrado, S., Karp, S.L., Elkon, K., Egido, J., and Neilson, E.G. (1996). Regulation of Fas and Fas ligand expression in cultured murine renal cells and in the kidney during endotoxemia. Am. J. Physiol. 271, F1193-1201. Ougolkov, A.V., and Billadeau, D.D. (2006). Targeting GSK-3: a promising approach for cancer therapy? Future Oncol. 2, 91-100. Pap, M., and Cooper, G.M. (1998). Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-kinase/Akt cell survival pathway. J. Bio. Chem. 273, 19929-19932. Pap, M., and Cooper, G.M. (2002). Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway. Mol. Cell. Biol. 22, 578-586. Pickup, J.C. (2004). Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care 27, 813-823. Plotnikov, E.Y., Kazachenko, A.V., Vyssokikh M.Y., et al. (2007) The role of mitochondria in oxidative and nitrosative stress during ischemia/reperfusion in the rat kidney. Kidney Int. 72, 1493-1502. Poljakovic, M., Nygren, J.M., and Persson, K. (2003). Signalling pathways regulating inducible nitric oxide synthase expression in human kidney epithelial cells. Eur. J. Pharmacol. 469, 21-28. Polychronopoulos, P., Magiatis, P., Skaltsounis A.L., Myrianthopoulos, V., Mikros, E., Tarricone, A., Musacchio, A., Roe, S.M., Pearl, L., Leost, M., et al. (2004). J. Med. Chem. 47, 935-946. Reynolds, J.L., Ignatowski, T.A., Sud, R., and Spengler, R.N. (2005). An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-alpha production culminating in increases in noradrenergic neurotransmission. Neuroscience 133, 519-531. Ring, D. B., Johnson, K. W., Henriksen, E. J., Nuss J. M., Goff, D., Kinnick, T. R., Ma, S. T., Reeder, J. W., Samuels, I., Slabiak, T., et al. (2003). Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52, 588-595. Rossig, L., Badorff, C., Holzmann, Y., Zeiher, A.M., and Dimmeler, S. (2002). Glycogen synthase kinase-3 couples Akt-dependent signaling to the regulation of p21Cip1 degradation. J. Bio. Chem. 277, 9684-9689. Russell, J.A. (2006). Management of sepsis. N. Engl. J. Med. 355, 1699-1713. Ryves, W.J., and Harwood A.J. (2001). Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem. Biophys. Res. Commun. 280, 720-725. Sastre, M., Klockgether, T., and Heneka, M.T. (2006). Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. Int. J. Dev. Neurosci. 24, 167-176. Schiepers, O.J., Wichers, M.C., and Maes, M. (2005). Cytokines and major depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 29, 201-217. Schmidt, C., Hocherl, K., and Bucher, M. (2007a). Cytokine-mediated regulation of urea transporters during experimental endotoxemia. Am. J. Physiol. 292, F1479-F1489. Schmidt, C., Hocherl, K., and Bucher, M. (2007b). Regulation of renal glucose transporters during severe inflammation. Am. J. Physiol. 292, F804-F811. Schmidt, C., Hocherl, K., Schweda, F., and Bucher, M. (2007c). Proinflammatory cytokines cause down-regulation of renal chloride entry pathways during sepsis. Crit. Care Med. 35, 2110-2119. Schrier, R.W., and Wang, W. (2004). Acute renal failure and sepsis. N. Engl. J. Med. 351, 159-169. Seeling J.M., Miller, J.R., Gil, R., Moon, R.T., White, R., and Virshup, D.M. (1999). Regulation of beta-Catenin signaling by the B56 subunit of protein phosphatase 2A. Science. 283, 2089-2091. Somervaille, T.C., Linch, D.C., and Khwaja, A. (2001). Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax. Blood 98, 1374-1381. Song, G.Y., Chung, C.S., Chaudry, I.H., and Ayala, A. (1999). What is the role of interleukin 10 in polymicrobial sepsis: anti-inflammatory agent or immunosuppressant? Surgery 126, 378-383. Song, L., De Sarno, P., and Jope, R.S. (2002). Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation. J. Biol. Chem. 277, 44701-44708. Soos, T.J., Meijer, L., and Nelson, P.J. (2006). CDK/GSK-3 inhibitors as a new approach for the treatment of proliferative renal diseases. Drug News Perspect. 19, 325-328. Takada, Y., Fang, X., Jamaluddin, M.S., Boyd, D.D., and Aggarwal, B.B. (2004). Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor. J. Biol. Chem. 279, 39541-39554. Thadhani, R., Pascual, M., and Bonventre, J.V. (1996). Acute renal failure. N. Engl. J. Med. 334, 1448-1460. Trinchieri, G., and Sher, A. (2007). Cooperation of Toll-like receptor signals in innate immune defence. Nat. Rev. Immunol. 7, 179-190. Uchino, S., Kellum, J.A., Bellomo, R., Doig, G.S., Morimatsu, H., Morgera, S., Schetz, M., Tan, I., Bouman, C., Macedo, E., et al. (2005). Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294, 813-818. Uysal, K.T., Wiesbrock, S.M., Marino, M.W., and Hotamisligil, G.S. (1997). Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389, 610-614. van der Poll, T., Marchant, A., Buurman, W.A., Berman, L., Keogh, C.V., Lazarus, D.D., Nguyen, L., Goldman, M., Moldawer, L.L., and Lowry, S.F. (1995). Endogenous IL-10 protects mice from death during septic peritonitis. J. Immunol. 155, 5397-5401. Wan, L., Bagshaw, S.M., Langenberg, C., Saotome, T., May, C., and Bellomo, R. (2008). Pathophysiology of septic acute kidney injury: what do we really know? Crit. Care Med. 36, S198-S203. Wan, L., Bellomo, R., Di Giantomasso, D., and Ronco, C. (2003). The pathogenesis of septic acute renal failure. Curr. Opin. Crit. Care 9, 496-502. Watcharasit, P., Bijur, G.N., Song, L., Zhu, J., Chen, X., and Jope, R.S. (2003). Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the action of p53. J. Bio. Chem. 278, 48872-48879. Whittle, B.J., Varga, C., Posa, A., Molnar, A., Collin, M., and Thiemermann, C. (2006). Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta. Br. J. Pharmacol. 147, 575-582. Woodgett, J.R., and Ohashi, P.S. (2005). GSK3: an in-Toll-erant protein kinase? Nat. Immunol. 6, 751-752. Wu, X., Guo, R., Wang, Y., and Cunningham, P.N. (2007). The role of ICAM-1 in endotoxin-induced acute renal failure. Am. J. Physiol. 293, F1262-F1271.
|