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研究生:呂宜蓉
研究生(外文):Yi-Jung Lu
論文名稱:電致表面改質對新型鐵基微型骨釘之影響研究
論文名稱(外文):Effect of electro-discharging modifications on new Fe-based mini-implant alloy
指導教授:歐耿良
指導教授(外文):Keng-Liang Ou
學位類別:碩士
校院名稱:臺北醫學大學
系所名稱:生醫材料暨工程研究所
學門:工程學門
學類:生醫工程學類
論文種類:學術論文
論文出版年:2009
畢業學年度:97
語文別:英文
論文頁數:50
中文關鍵詞:鐵鋁錳重鑄層放電生物相容性
外文關鍵詞:Fe-Al-MnRecast layerElectro-dischargingBiocompatibility
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本研究以放電加工的方式使鐵鋁錳合金表面形成一層奈微米複合性孔洞的重鑄層,重鑄層為?蚻菑哅e0.6Mn5.4C2(κ相)之碳化物,此相對於生物相容性有著重要的意義。而再以物理及化學性的分析儀器測試表面之成分、元素、膜厚、孔洞大小及結構,之後將對符合要求的試片於無塵室加以清洗、消毒後,即以這些試片進行細胞培養,經特定時間分別對細胞的攀附、增殖作不同的測試, 並加以比較不同條件下測試的結果。
本研究主要是在探討鐵鋁錳合金植體表面經由放電加工方式製作出重鑄層,並以細胞實驗在不同條件下的生長情形,此外更進一步探討微奈米複合式孔洞的表面與骨整合的癒合機制並進行比較,此結果可對縮短植入於骨內的植體,如牙科植體的骨整合癒合時間有所助益。
This investigation elucidates the biocompatibility and microstructural variation of Fe-Al-Mn and electro-discharged Fe-Al-Mn alloys. A recast layer was formed on the alloy surface, following electro-discharged machining. ??-phase and Fe0.6Mn5.4C2 carbide (κ-carbide) were formed on the recast layer following electro-discharging. The ??-phase and κ-carbide are nanostructures. The nano-(??-phase + κ-carbide) have important roles in forming nanostructured oxide layer. In order to realize chemical composition, energy dispersive X-ray spectrometer (EDS) and X-ray photoelectron spectrometer (XPS) were performed. XPS was performed to detect the oxide film thickness by depth profile analysis. Pore sizes were observed by field emission scanning electron microscopy (FESEM). Microstructural variation was analyzed by cross-section transmission electron microscope (XTEM) and transmission electron microscope (TEM).Furthermore, electro-discharging not only generates a nanostructural recast layer, but also converts the alloy surface into a nanostructured oxide surface, increasing the alloy biocompatibility.
Contents
Contents……………………………………………………………………………1
Figure captions…………………………………………………………………….2
中文摘要…………………………………………………………………………...3
Abstract……………………………………………………………………………4
Chapter 1 Introduction………………………………………………...................5
1.1 General background…………………….………………………..5
1.2 Motivation of this study……………….…………………………6
1.3 Purpose of this study……………………………………………6
1.4 Hypothesis of this study……..…………………………………7
1.5 Organization of the thesis………………………………………7
Chapter 2 Literature Review…………...……………………………………….8
2.1 Property of Fe-Al-Mn alloys………….....…………………8
2.2Osseo/osetointegration of Fe-Al-Mn alloy…………11
2.3 Relationship of osseo/oseteointegration and oxide layer..…….12
Chapter 3 Experimental Procedure…………...………………………………..13
3.1 Fe-Al-Mn alloy implant preparation………………………….13
3.2 Physical and Chemical properties of dental implant with and without surface treatments...…………….…..…………………13
3.3 Fe-Al-Mn alloy implant biocompatibility …………………......15
Chapter 4 Results and Discussion………………………………………………17
Chapter 5 Conclusion……………………………………………………………25
Acknowledgement………………………………………………………………..26
Reference…………………………………………………………………………27


Figure captions
Figure 3.1 Energy Dispersive X-ray Spectroscopy (EDXS)………………...…34
Figure 3.2 Grazing-Incidence X-ray Diffraction (GIXRD)……………...……35
Figure 3.3 Transmission Electron Microscope(TEM)…………………………36
Figure 3.4 Field-Emission Scanning Electron Microscope(FE-SEM)……...…37
Figure 4.1 Fi Cross-sectional SEM morphology of electro-discharged Fe-Al-Mn alloy…………………………………………………………………….38
Figure 4.2 XRD spectra of treated and untreated Fe-Al-Mn alloy…………….39
Figure 4.3 TEM micrographs and selected area diffraction patterns (SADP) of treated and untreated Fe-Al-Mn alloy(a) without treatment, and (b) with treatment…………………………………………………………40
Figure 4.4 Highly magnified SEM image Fe-Al-Mn alloy: (a) without treatment, and (b) with treatment………………………………………………...42
Figure 4.5 Highly magnified SEM image of NIH3T3 cell cultured for three days on Fe-Al-Mn alloy: (a)、(c)、(e) without treatment, and (b)、(d)、(f) with treatment………………………………………………………………..44
Figure 4.6 Cell counting results for Fe-Al-Mn with and without EDM treatments……………………………………………………………….50
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